JPS5492967A - Alpha-tocopherol-13-cis-vitamin a acid ester - Google Patents

Alpha-tocopherol-13-cis-vitamin a acid ester

Info

Publication number
JPS5492967A
JPS5492967A JP15763077A JP15763077A JPS5492967A JP S5492967 A JPS5492967 A JP S5492967A JP 15763077 A JP15763077 A JP 15763077A JP 15763077 A JP15763077 A JP 15763077A JP S5492967 A JPS5492967 A JP S5492967A
Authority
JP
Japan
Prior art keywords
tocopherol
vitamin
cis
acid ester
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15763077A
Other languages
Japanese (ja)
Other versions
JPS6056156B2 (en
Inventor
Yasuhiro Komatsu
Michiko Nagai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Priority to JP15763077A priority Critical patent/JPS6056156B2/en
Priority to US06/154,415 priority patent/US4320141A/en
Priority to PCT/JP1978/000055 priority patent/WO1979000401A1/en
Priority to EP79900025A priority patent/EP0008573A1/en
Publication of JPS5492967A publication Critical patent/JPS5492967A/en
Publication of JPS6056156B2 publication Critical patent/JPS6056156B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:α-Tocopherol-13-cis-vitamin A acid ester of the formula.
USE: Very low-toxicity antitumorigenic agent, it is effective in remedy and prevention of tumor production on epithelial cells
PREPARATION: The esterifecation of 13-cis-vitamin A acid with a natural mixture of tocopherol containing α-tocopherol, (dl-α-tocopherol, d-α-tocopherol, and 1-α- tocopherol) by a conventional method, or the esterification of all-trans vitamin A acid with α-tocopherol and subsequent isomerization of the resulting all-trans vitamin A acid ester by conventional methods give the objective α-tocopherol-13- cis-vitamin A acid ester.
COPYRIGHT: (C)1979,JPO&Japio
JP15763077A 1977-12-16 1977-12-29 α-tocopherol-13-cis-vitamin A acid ester Expired JPS6056156B2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP15763077A JPS6056156B2 (en) 1977-12-29 1977-12-29 α-tocopherol-13-cis-vitamin A acid ester
US06/154,415 US4320141A (en) 1977-12-16 1978-12-14 Antitumor agent
PCT/JP1978/000055 WO1979000401A1 (en) 1977-12-16 1978-12-14 Anti-tumor agent
EP79900025A EP0008573A1 (en) 1977-12-16 1978-12-14 Anti-tumor agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15763077A JPS6056156B2 (en) 1977-12-29 1977-12-29 α-tocopherol-13-cis-vitamin A acid ester

Publications (2)

Publication Number Publication Date
JPS5492967A true JPS5492967A (en) 1979-07-23
JPS6056156B2 JPS6056156B2 (en) 1985-12-09

Family

ID=15653912

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15763077A Expired JPS6056156B2 (en) 1977-12-16 1977-12-29 α-tocopherol-13-cis-vitamin A acid ester

Country Status (1)

Country Link
JP (1) JPS6056156B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2859961B2 (en) * 1991-06-04 1999-02-24 マリゲン ソシエテ アノニム Novel biosurfactant esters and phosphatides of vitamin D and vitamin E compounds, methods for their preparation, natural dispersants containing these compounds, and their use in treating tumors
JP2005068011A (en) * 2003-06-24 2005-03-17 Nihon Green & Garden Corp Mixed microgranule for weeding

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2859961B2 (en) * 1991-06-04 1999-02-24 マリゲン ソシエテ アノニム Novel biosurfactant esters and phosphatides of vitamin D and vitamin E compounds, methods for their preparation, natural dispersants containing these compounds, and their use in treating tumors
JP2005068011A (en) * 2003-06-24 2005-03-17 Nihon Green & Garden Corp Mixed microgranule for weeding

Also Published As

Publication number Publication date
JPS6056156B2 (en) 1985-12-09

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