JPS5481282A - Novel quinazoline compound*its manufacture and heart blood vessel regulating agent made from it - Google Patents

Novel quinazoline compound*its manufacture and heart blood vessel regulating agent made from it

Info

Publication number
JPS5481282A
JPS5481282A JP14094678A JP14094678A JPS5481282A JP S5481282 A JPS5481282 A JP S5481282A JP 14094678 A JP14094678 A JP 14094678A JP 14094678 A JP14094678 A JP 14094678A JP S5481282 A JPS5481282 A JP S5481282A
Authority
JP
Japan
Prior art keywords
manufacture
blood vessel
regulating agent
agent made
heart blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14094678A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5623991B2 (xx
Inventor
Fureizaa Kiyanberu Saimon
Kurisutofuaa Daniruuitsu Jiyon
Uiriamu Guriingurasu Korin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPS5481282A publication Critical patent/JPS5481282A/ja
Publication of JPS5623991B2 publication Critical patent/JPS5623991B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
JP14094678A 1977-11-16 1978-11-15 Novel quinazoline compound*its manufacture and heart blood vessel regulating agent made from it Granted JPS5481282A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4758377 1977-11-16
GB7844533A GB2010824B (en) 1977-11-16 1978-11-15 Therapeutic agents

Publications (2)

Publication Number Publication Date
JPS5481282A true JPS5481282A (en) 1979-06-28
JPS5623991B2 JPS5623991B2 (xx) 1981-06-03

Family

ID=26266083

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14094678A Granted JPS5481282A (en) 1977-11-16 1978-11-15 Novel quinazoline compound*its manufacture and heart blood vessel regulating agent made from it

Country Status (12)

Country Link
JP (1) JPS5481282A (xx)
AT (1) AT365183B (xx)
AU (1) AU509348B2 (xx)
BE (1) BE872023A (xx)
CA (1) CA1088068A (xx)
CH (1) CH637131A5 (xx)
DE (1) DE2849392A1 (xx)
FR (1) FR2409267A1 (xx)
GB (1) GB2010824B (xx)
LU (1) LU80531A1 (xx)
NL (1) NL174646C (xx)
SE (1) SE7811770L (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55104278A (en) * 1979-01-31 1980-08-09 Pfizer Cardiovascular regulating agent quinazoline

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2481278A1 (fr) * 1980-04-28 1981-10-30 Synthelabo Nouveaux derives de piperidine, leur procede de preparation et leur application en therapeutique
FR2514353A2 (fr) * 1980-04-28 1983-04-15 Synthelabo Derives de piperidine et leur application en therapeutique
JPS62212385A (ja) * 1986-03-13 1987-09-18 Kotobuki Seiyaku Kk キナゾリン誘導体並びに血圧降下剤及びその製法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55104278A (en) * 1979-01-31 1980-08-09 Pfizer Cardiovascular regulating agent quinazoline
JPS5728711B2 (xx) * 1979-01-31 1982-06-18

Also Published As

Publication number Publication date
FR2409267A1 (fr) 1979-06-15
CH637131A5 (de) 1983-07-15
NL174646B (nl) 1984-02-16
FR2409267B1 (xx) 1981-02-27
AU509348B2 (en) 1980-05-08
LU80531A1 (fr) 1980-06-05
ATA816678A (de) 1981-05-15
SE7811770L (sv) 1979-05-17
AU4157678A (en) 1979-05-24
AT365183B (de) 1981-12-28
CA1088068A (en) 1980-10-21
GB2010824A (en) 1979-07-04
GB2010824B (en) 1982-06-16
JPS5623991B2 (xx) 1981-06-03
BE872023A (fr) 1979-05-14
NL174646C (nl) 1984-07-16
NL7811236A (nl) 1979-05-18
DE2849392A1 (de) 1979-05-23

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