JPS5416422A - 11fluoromethyl substitutedd alkylamine and process for preparing same - Google Patents

11fluoromethyl substitutedd alkylamine and process for preparing same

Info

Publication number
JPS5416422A
JPS5416422A JP6501478A JP6501478A JPS5416422A JP S5416422 A JPS5416422 A JP S5416422A JP 6501478 A JP6501478 A JP 6501478A JP 6501478 A JP6501478 A JP 6501478A JP S5416422 A JPS5416422 A JP S5416422A
Authority
JP
Japan
Prior art keywords
substitutedd
alkylamine
preparing same
preparing
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6501478A
Other languages
Japanese (ja)
Other versions
JPS6123177B2 (en
Inventor
Koronitsushiyu Jiyanosu
Aran Pachietsuto Aasaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5416422A publication Critical patent/JPS5416422A/en
Publication of JPS6123177B2 publication Critical patent/JPS6123177B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
JP6501478A 1977-06-01 1978-06-01 11fluoromethyl substitutedd alkylamine and process for preparing same Granted JPS5416422A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80235077A 1977-06-01 1977-06-01

Publications (2)

Publication Number Publication Date
JPS5416422A true JPS5416422A (en) 1979-02-07
JPS6123177B2 JPS6123177B2 (en) 1986-06-04

Family

ID=25183471

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6501478A Granted JPS5416422A (en) 1977-06-01 1978-06-01 11fluoromethyl substitutedd alkylamine and process for preparing same

Country Status (6)

Country Link
EP (1) EP0000036B1 (en)
JP (1) JPS5416422A (en)
DE (1) DE2861148D1 (en)
DK (1) DK240578A (en)
IE (1) IE46910B1 (en)
IT (1) IT1104712B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5466676A (en) * 1977-10-19 1979-05-29 Merrell Toraude & Co Alphaahalomethylderivative of histamine and relative compounds
JPS6210070A (en) * 1985-07-03 1987-01-19 マイルズ　ラボラトリ−ス　インコ−ポレ−テッド Histamine derivative, immunogenic conjugate and antibody raised against same

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3872678A (en) * 1977-09-01 1980-02-14 Merrell Toraude & Co Alpha-halomethyl amines
US4326071A (en) * 1977-09-28 1982-04-20 Merrell Toraude Et Compagnie Halomethyl derivatives of gamma-aminobutyric acid and related compounds
NZ194348A (en) * 1979-07-26 1982-09-14 Merrell Toraude & Co Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions
US4542802A (en) * 1982-04-02 1985-09-24 Woodward Governor Company Engine and transmission control system for combines and the like

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL270984A (en) * 1960-11-05
GB1218135A (en) * 1967-07-28 1971-01-06 Abbott Lab Substituted phenethylamine derivatives
US3839170A (en) * 1970-08-03 1974-10-01 Merck & Co Inc Process for the preparation of 3-fluoro-d-alanine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5466676A (en) * 1977-10-19 1979-05-29 Merrell Toraude & Co Alphaahalomethylderivative of histamine and relative compounds
JPS6223753B2 (en) * 1977-10-19 1987-05-25 Merrell Toraude & Co
JPS6210070A (en) * 1985-07-03 1987-01-19 マイルズ　ラボラトリ−ス　インコ−ポレ−テッド Histamine derivative, immunogenic conjugate and antibody raised against same

Also Published As

Publication number Publication date
IE46910B1 (en) 1983-11-02
EP0000036A1 (en) 1978-12-20
EP0000036B1 (en) 1981-10-14
IE781076L (en) 1978-12-01
DK240578A (en) 1978-12-02
IT1104712B (en) 1985-10-28
IT7849634A0 (en) 1978-05-31
DE2861148D1 (en) 1981-12-24
JPS6123177B2 (en) 1986-06-04

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