JPS54128564A - Preparation of gamma-alkyl-gamma-lactone - Google Patents
Preparation of gamma-alkyl-gamma-lactoneInfo
- Publication number
- JPS54128564A JPS54128564A JP3413478A JP3413478A JPS54128564A JP S54128564 A JPS54128564 A JP S54128564A JP 3413478 A JP3413478 A JP 3413478A JP 3413478 A JP3413478 A JP 3413478A JP S54128564 A JPS54128564 A JP S54128564A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- lactone
- hcl
- gamma
- dihalo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000005695 dehalogenation reaction Methods 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 239000002304 perfume Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000686 lactone group Chemical group 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- -1 trichloroacetic acid ester Chemical class 0.000 abstract 1
- 239000004711 α-olefin Substances 0.000 abstract 1
Landscapes
- Furan Compounds (AREA)
Abstract
PURPOSE: To prepare the title compound useful as a raw material of perfumes, pharmaceuticals, pesticides, etc., and as a perfume, easily, by the dehalogenation of α-halo or α,α-dihalo-γ-alkyl-γ-lactone in the presence of Zn-HCl in acetic acid.
CONSTITUTION: An α-halo or α,α-dihalo-γ-alkyl-γ-lactone of formula I (R is alkyl; X1 is halogen; X2 is halogen, H) is dehalogenated by Zn-HCl treatment in acetic acid to afford γ-alkyl-γ-lactone of formula I. The compound I is easily prepared by the reaction of an α-olefin with di- or trichloroacetic acid ester. The equivalent ratio of Zn to the compound I is 1.5W3 to 1, and the HCl is pref. conc HCl of a concentration of ≥12N.
EFFECT: The dehalogenation reaction is selectively carried out without cleavage or reduction of the lactone ring.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3413478A JPS54128564A (en) | 1978-03-27 | 1978-03-27 | Preparation of gamma-alkyl-gamma-lactone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3413478A JPS54128564A (en) | 1978-03-27 | 1978-03-27 | Preparation of gamma-alkyl-gamma-lactone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS54128564A true JPS54128564A (en) | 1979-10-05 |
Family
ID=12405745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3413478A Pending JPS54128564A (en) | 1978-03-27 | 1978-03-27 | Preparation of gamma-alkyl-gamma-lactone |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS54128564A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4954623A (en) * | 1989-03-20 | 1990-09-04 | Eli Lilly And Company | Recovery of difluoro sugar |
-
1978
- 1978-03-27 JP JP3413478A patent/JPS54128564A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4954623A (en) * | 1989-03-20 | 1990-09-04 | Eli Lilly And Company | Recovery of difluoro sugar |
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