JPS54109990A - Crystals of cyclophosphamide - Google Patents
Crystals of cyclophosphamideInfo
- Publication number
- JPS54109990A JPS54109990A JP1630478A JP1630478A JPS54109990A JP S54109990 A JPS54109990 A JP S54109990A JP 1630478 A JP1630478 A JP 1630478A JP 1630478 A JP1630478 A JP 1630478A JP S54109990 A JPS54109990 A JP S54109990A
- Authority
- JP
- Japan
- Prior art keywords
- cyclophosphamide
- formula
- preparation
- room temperature
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:Water-free crystals of cyclophosphamide given as the formula.
USE: Remedy for giant follicular lymphoma, Hodgkin's disease, lymphatic leukaemia and reticulo sarcoma. The anhydrous crystal form improves the shelf stability and processability on preparation.
PREPARATION: An anhydrous oil of cyclophosphamide of the formula is dissolved in an ether solvent at room temperature to 100°C and crystal seeds of cyclophosphamide are added to the solution. Then the solution is stood at 0°C to room temperature to crystallize out the objective compound.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1630478A JPS54109990A (en) | 1978-02-14 | 1978-02-14 | Crystals of cyclophosphamide |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1630478A JPS54109990A (en) | 1978-02-14 | 1978-02-14 | Crystals of cyclophosphamide |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54109990A true JPS54109990A (en) | 1979-08-29 |
Family
ID=11912791
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1630478A Pending JPS54109990A (en) | 1978-02-14 | 1978-02-14 | Crystals of cyclophosphamide |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54109990A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114437130A (en) * | 2022-02-18 | 2022-05-06 | 安徽普利药业有限公司 | Method for refining cyclophosphamide |
-
1978
- 1978-02-14 JP JP1630478A patent/JPS54109990A/en active Pending
Non-Patent Citations (1)
Title |
---|
JOURNAL OF THE AMERICAN SOCIETY=1977 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114437130A (en) * | 2022-02-18 | 2022-05-06 | 安徽普利药业有限公司 | Method for refining cyclophosphamide |
CN114437130B (en) * | 2022-02-18 | 2024-05-17 | 安徽普利药业有限公司 | Process for purifying cyclophosphamide |
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