JPS5338617A - Preparation of hepatitis-b vaccine - Google Patents

Preparation of hepatitis-b vaccine

Info

Publication number
JPS5338617A
JPS5338617A JP11273376A JP11273376A JPS5338617A JP S5338617 A JPS5338617 A JP S5338617A JP 11273376 A JP11273376 A JP 11273376A JP 11273376 A JP11273376 A JP 11273376A JP S5338617 A JPS5338617 A JP S5338617A
Authority
JP
Japan
Prior art keywords
vaccine
hepatitis
preparation
treatkng
infectivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11273376A
Other languages
Japanese (ja)
Other versions
JPS5840930B2 (en
Inventor
Satoru Funakoshi
Yatsuhiro Kamimura
Tsunekazu Fukushima
Toshihiko Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Priority to JP11273376A priority Critical patent/JPS5840930B2/en
Publication of JPS5338617A publication Critical patent/JPS5338617A/en
Publication of JPS5840930B2 publication Critical patent/JPS5840930B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To prepare high purity hepatitis-B vaccine having high antigenicity and free of infectivity, by heat-treatkng human blood-plasma containing hepatitisB virus, and purifying by the ammonium sulfate fractionation and gel filtration.
COPYRIGHT: (C)1978,JPO&Japio
JP11273376A 1976-09-20 1976-09-20 Manufacturing method for hepatitis B vaccine Expired JPS5840930B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11273376A JPS5840930B2 (en) 1976-09-20 1976-09-20 Manufacturing method for hepatitis B vaccine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11273376A JPS5840930B2 (en) 1976-09-20 1976-09-20 Manufacturing method for hepatitis B vaccine

Publications (2)

Publication Number Publication Date
JPS5338617A true JPS5338617A (en) 1978-04-08
JPS5840930B2 JPS5840930B2 (en) 1983-09-08

Family

ID=14594172

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11273376A Expired JPS5840930B2 (en) 1976-09-20 1976-09-20 Manufacturing method for hepatitis B vaccine

Country Status (1)

Country Link
JP (1) JPS5840930B2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59101426A (en) * 1982-11-29 1984-06-12 Green Cross Corp:The Preparation of vaccine for preventing infection of b-type hepatitis
JPS6136228A (en) * 1984-07-09 1986-02-20 ジエネンテク，インコーポレイテツド Purification of hepatitis surface antigen and product
US7038016B2 (en) * 2001-08-21 2006-05-02 Apex Bioscience, Inc. Methods for purification of an activated PEG solution and for the synthesis of a modified hemoglobin solution

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59101426A (en) * 1982-11-29 1984-06-12 Green Cross Corp:The Preparation of vaccine for preventing infection of b-type hepatitis
US4565697A (en) * 1982-11-29 1986-01-21 Green Cross Corporation Process for producing a hepatitis B infection preventing vaccine
JPH0585526B2 (en) * 1982-11-29 1993-12-07 Green Cross Corp
JPS6136228A (en) * 1984-07-09 1986-02-20 ジエネンテク，インコーポレイテツド Purification of hepatitis surface antigen and product
US7038016B2 (en) * 2001-08-21 2006-05-02 Apex Bioscience, Inc. Methods for purification of an activated PEG solution and for the synthesis of a modified hemoglobin solution

Also Published As

Publication number Publication date
JPS5840930B2 (en) 1983-09-08

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