JPS53148536A - Carcinostatic agent containing trans-4-aminomethylcyclohexane-1-carboxylic acid derivative - Google Patents

Carcinostatic agent containing trans-4-aminomethylcyclohexane-1-carboxylic acid derivative

Info

Publication number
JPS53148536A
JPS53148536A JP4514677A JP4514677A JPS53148536A JP S53148536 A JPS53148536 A JP S53148536A JP 4514677 A JP4514677 A JP 4514677A JP 4514677 A JP4514677 A JP 4514677A JP S53148536 A JPS53148536 A JP S53148536A
Authority
JP
Japan
Prior art keywords
aminomethylcyclohexane
carboxylic acid
acid derivative
agent containing
carcinostatic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4514677A
Other languages
Japanese (ja)
Other versions
JPS6011685B2 (en
Inventor
Yoshiro Asano
Akira Iizuka
Takami Fujii
Satoshi Enomoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Priority to JP52045146A priority Critical patent/JPS6011685B2/en
Priority to DE19782857555 priority patent/DE2857555C3/en
Priority to DE2817558A priority patent/DE2817558C2/en
Priority to FR7811910A priority patent/FR2387650A1/en
Publication of JPS53148536A publication Critical patent/JPS53148536A/en
Publication of JPS6011685B2 publication Critical patent/JPS6011685B2/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To provide a carcinostatic agent having reduced side effects, containing trans-4-aminomethylcyclohexane-1-carboxylic acid as an effective component.
COPYRIGHT: (C)1978,JPO&Japio
JP52045146A 1977-04-21 1977-04-21 Trans-4-aminomethylcyclohexane-1-carboxylic acid derivative cancer drug Expired JPS6011685B2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP52045146A JPS6011685B2 (en) 1977-04-21 1977-04-21 Trans-4-aminomethylcyclohexane-1-carboxylic acid derivative cancer drug
DE19782857555 DE2857555C3 (en) 1977-04-21 1978-04-21 Trans-4-palmitoylaminomethyl-cyclohexane-1-carboxylic acid and salts thereof and anti-tumor agents containing the same
DE2817558A DE2817558C2 (en) 1977-04-21 1978-04-21 Antitumor agents containing derivatives of trans-4- (aminomethyl) cyclohexane-1-carboxylic acid
FR7811910A FR2387650A1 (en) 1977-04-21 1978-04-21 Antitumour N-acyl-tranexamic acid derivs. - prepd. by reacting trans-4-aminomethyl-cyclohexane-carboxylic acid with a fatty acid halide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52045146A JPS6011685B2 (en) 1977-04-21 1977-04-21 Trans-4-aminomethylcyclohexane-1-carboxylic acid derivative cancer drug

Publications (2)

Publication Number Publication Date
JPS53148536A true JPS53148536A (en) 1978-12-25
JPS6011685B2 JPS6011685B2 (en) 1985-03-27

Family

ID=12711132

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52045146A Expired JPS6011685B2 (en) 1977-04-21 1977-04-21 Trans-4-aminomethylcyclohexane-1-carboxylic acid derivative cancer drug

Country Status (3)

Country Link
JP (1) JPS6011685B2 (en)
DE (1) DE2817558C2 (en)
FR (1) FR2387650A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108976146A (en) * 2017-05-31 2018-12-11 首都医科大学 The positive positive hexanoyl ArAA of hexanoyl ammonia first cyclic amide base of amino, synthesis, activity and application
CN109081790A (en) * 2017-06-13 2018-12-25 首都医科大学 The positive positive hexanoyl basic amino acid of hexanoyl amino first cyclic amide base of amino, synthesis, activity and application

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2280365A1 (en) * 1974-08-01 1976-02-27 Rorer Italiana Spa ALKANOYLIC DERIVATIVES OF AMINOMETHYLCYCLOHEXANECARBOXYLIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108976146A (en) * 2017-05-31 2018-12-11 首都医科大学 The positive positive hexanoyl ArAA of hexanoyl ammonia first cyclic amide base of amino, synthesis, activity and application
CN108976146B (en) * 2017-05-31 2020-11-27 首都医科大学 Amino n-hexanoyl methyl cyclamido n-hexanoyl aromatic amino acid, synthesis, activity and application thereof
CN109081790A (en) * 2017-06-13 2018-12-25 首都医科大学 The positive positive hexanoyl basic amino acid of hexanoyl amino first cyclic amide base of amino, synthesis, activity and application
CN109081790B (en) * 2017-06-13 2021-02-12 首都医科大学 Amino n-hexanoyl amido methyl-n-hexanoyl basic amino acid, synthesis, activity and application thereof

Also Published As

Publication number Publication date
DE2817558A1 (en) 1978-10-26
FR2387650A1 (en) 1978-11-17
JPS6011685B2 (en) 1985-03-27
DE2817558C2 (en) 1984-01-26
FR2387650B1 (en) 1982-01-29

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