JPS5285177A - Synthesis of 3-(methylmercapto)propylamino-bleomycin - Google Patents

Synthesis of 3-(methylmercapto)propylamino-bleomycin

Info

Publication number
JPS5285177A
JPS5285177A JP15298975A JP15298975A JPS5285177A JP S5285177 A JPS5285177 A JP S5285177A JP 15298975 A JP15298975 A JP 15298975A JP 15298975 A JP15298975 A JP 15298975A JP S5285177 A JPS5285177 A JP S5285177A
Authority
JP
Japan
Prior art keywords
methylmercapto
propylamino
bleomycin
synthesis
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15298975A
Other languages
Japanese (ja)
Other versions
JPS6039680B2 (en
Inventor
Tomohisa Takita
Akio Fujii
Takeyo Fukuoka
Hiroko Ito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Priority to JP15298975A priority Critical patent/JPS6039680B2/en
Publication of JPS5285177A publication Critical patent/JPS5285177A/en
Publication of JPS6039680B2 publication Critical patent/JPS6039680B2/en
Expired legal-status Critical Current

Links

Abstract

PURPOSE: Title compound, an excellent carcinostatic antibiotic, is prepared in good yield by pyrolysis of the corresponding S,S-dimethylmercapto compound in the presence of a sulfur compound.
COPYRIGHT: (C)1977,JPO&Japio
JP15298975A 1975-12-22 1975-12-22 Method for producing 3-(methylmercapto)propylaminobleomycin Expired JPS6039680B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15298975A JPS6039680B2 (en) 1975-12-22 1975-12-22 Method for producing 3-(methylmercapto)propylaminobleomycin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15298975A JPS6039680B2 (en) 1975-12-22 1975-12-22 Method for producing 3-(methylmercapto)propylaminobleomycin

Publications (2)

Publication Number Publication Date
JPS5285177A true JPS5285177A (en) 1977-07-15
JPS6039680B2 JPS6039680B2 (en) 1985-09-06

Family

ID=15552516

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15298975A Expired JPS6039680B2 (en) 1975-12-22 1975-12-22 Method for producing 3-(methylmercapto)propylaminobleomycin

Country Status (1)

Country Link
JP (1) JPS6039680B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0035374A2 (en) * 1980-03-01 1981-09-09 JOHN WYETH & BROTHER LIMITED Piperidyl - urea, - thiourea and - guanidine derivatives, and intermediates therefor, processes for preparing them and pharmaceutical compositions containing the derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0035374A2 (en) * 1980-03-01 1981-09-09 JOHN WYETH & BROTHER LIMITED Piperidyl - urea, - thiourea and - guanidine derivatives, and intermediates therefor, processes for preparing them and pharmaceutical compositions containing the derivatives

Also Published As

Publication number Publication date
JPS6039680B2 (en) 1985-09-06

Similar Documents

Publication Publication Date Title
JPS5285177A (en) Synthesis of 3-(methylmercapto)propylamino-bleomycin
JPS53134060A (en) Novel polysaccharide
JPS5227782A (en) Preparation of uridine derivatives
JPS5233624A (en) Preparation of leucylnitroagmatines
JPS52106860A (en) Synthesis of 2-oxy substituted tetrahydrofurans
JPS52100483A (en) Isoleucomycin a5
JPS5211913A (en) Floating head security structure
JPS52108092A (en) Preparation of bicyclomycin
JPS5416451A (en) 3,5-dichloro-4-fluoropheyl isocyanate and its preparation
JPS5210240A (en) Preparation of novel antibiotics derivatives
JPS5265281A (en) Preparation of n4-dimethylamino methylene-arabinofuranosil cytosine
JPS5414953A (en) 1-aminocarbonyltricyclo(4,3,1,12,5)undecane
JPS5223067A (en) Novel synthesis of 2-aminomethyl-1- ethylpyrrolidine
JPS5414954A (en) 1-cyanotricylco(4,3,1,12,5)undecane
JPS5271458A (en) Synthesis of 1alpha-acyloxyprovitamine d compounds
JPS5422353A (en) 2-chloro-2-cyano-7-alkylidene-bicyclo(2,2,1)-5-heptene and its preparation
JPS52118461A (en) Thiophene-silylenole-ether
JPS532476A (en) Synthesis of 4-substituted-dithio-2-azetidinone derivatives
JPS5346955A (en) Polyoxypregnane type compound
JPS5285172A (en) 2-pyridylthio-zincoxy complex
JPS52131590A (en) Bis-trimethoxybenzylpiperazino-alkanes
JPS5321169A (en) Novel lactone derivatives
JPS5412354A (en) Cyclohexyldichlorosilane
JPS53111052A (en) 4-endo-hydroxy-4-homoisotwistane
JPS53108958A (en) Tricyclo(5,2,2,0 4,8)undecane