JPS5283435A - Preparation of prostaglandin analogs - Google Patents
Preparation of prostaglandin analogsInfo
- Publication number
- JPS5283435A JPS5283435A JP15659775A JP15659775A JPS5283435A JP S5283435 A JPS5283435 A JP S5283435A JP 15659775 A JP15659775 A JP 15659775A JP 15659775 A JP15659775 A JP 15659775A JP S5283435 A JPS5283435 A JP S5283435A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- prostaglandin analogs
- hydroxymethyl
- carboxyl
- protected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003180 prostaglandins Chemical class 0.000 title abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: Prostaglandin analogs expressed by the formula I: (Z1 is carboxyl or protected carboxyl; Z2 is hydroxyl, etc.; Z3 is hydroxymethyl which is protected hydroxy, etc.; Z4 is alkyl, etc.; Z5 is H, etc.). For example, (oα, 11α, 13E, 15S)-9,15-dihydroxy-11-hydroxymethyl-prosta-13-ene-1 acid.
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15659775A JPS5852993B2 (en) | 1975-12-30 | 1975-12-30 | Prostaglandin Luijikagoubutsuno Seizouhouhou |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15659775A JPS5852993B2 (en) | 1975-12-30 | 1975-12-30 | Prostaglandin Luijikagoubutsuno Seizouhouhou |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5283435A true JPS5283435A (en) | 1977-07-12 |
JPS5852993B2 JPS5852993B2 (en) | 1983-11-26 |
Family
ID=15631225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15659775A Expired JPS5852993B2 (en) | 1975-12-30 | 1975-12-30 | Prostaglandin Luijikagoubutsuno Seizouhouhou |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5852993B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022270344A1 (en) | 2021-06-23 | 2022-12-29 | 株式会社ランドビジネス | Massaging device |
-
1975
- 1975-12-30 JP JP15659775A patent/JPS5852993B2/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022270344A1 (en) | 2021-06-23 | 2022-12-29 | 株式会社ランドビジネス | Massaging device |
Also Published As
Publication number | Publication date |
---|---|
JPS5852993B2 (en) | 1983-11-26 |
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