JPS5283379A - Synthesis of carbostyril derivatives - Google Patents
Synthesis of carbostyril derivativesInfo
- Publication number
- JPS5283379A JPS5283379A JP15714075A JP15714075A JPS5283379A JP S5283379 A JPS5283379 A JP S5283379A JP 15714075 A JP15714075 A JP 15714075A JP 15714075 A JP15714075 A JP 15714075A JP S5283379 A JPS5283379 A JP S5283379A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- carbostyril derivatives
- synthesis
- formula
- bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: 5-(α-Substd. aminoalkanoyl- carbostyril derivatives of formula I (R1 is H, 1W4C alkyl, aralkyl bearing 1W4C alkyl; R2 is H, 1W3C alkyl; A is 1W4C alkyleneoxy, satd. bond; B is phenyl, radical of formula III, IV, or V; dotted line at 3, 4-bond represents satd. or double bond) and 5- [(2-substd. amino-1-hydroxy) alkyl] carbostyril derivatives of formula II; for example, 5-[(1-methyl-2-phenylethyl) amnioacetyl] -8-hydroxycarbostyril hydrochloride.
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50157140A JPS5913510B2 (en) | 1975-12-26 | 1975-12-26 | Calbostyril Yudou Tainoseizohou |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50157140A JPS5913510B2 (en) | 1975-12-26 | 1975-12-26 | Calbostyril Yudou Tainoseizohou |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5283379A true JPS5283379A (en) | 1977-07-12 |
JPS5913510B2 JPS5913510B2 (en) | 1984-03-30 |
Family
ID=15643057
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP50157140A Expired JPS5913510B2 (en) | 1975-12-26 | 1975-12-26 | Calbostyril Yudou Tainoseizohou |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5913510B2 (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57154129A (en) * | 1981-03-16 | 1982-09-22 | Otsuka Pharmaceut Co Ltd | Cardiotonic drug |
JPS60208965A (en) * | 1983-12-24 | 1985-10-21 | Tanabe Seiyaku Co Ltd | Novel carbostyril derivative and its preparation |
US6653323B2 (en) | 2001-11-13 | 2003-11-25 | Theravance, Inc. | Aryl aniline β2 adrenergic receptor agonists |
US6670376B1 (en) | 2001-11-13 | 2003-12-30 | Theravance, Inc. | Aryl aniline β2 adrenergic receptor agonists |
US7399863B2 (en) | 2003-09-22 | 2008-07-15 | Theravance, Inc. | Amino-substituted ethylamino β2 adrenergic receptor agonists |
US7402673B2 (en) | 2004-06-03 | 2008-07-22 | Theravance, Inc. | Diamine β2 adrenergic receptor agonists |
US7566785B2 (en) | 2004-09-10 | 2009-07-28 | Theravance, Inc. | Amidine substituted aryl aniline compounds |
US7582765B2 (en) | 2003-05-08 | 2009-09-01 | Theravance, Inc. | Aryl aniline β2 adrenergic receptor agonists |
US7622467B2 (en) | 2004-01-12 | 2009-11-24 | Theravance, Inc. | Aryl aniline derivatives as β2 adrenergic receptor agonists |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0453380Y2 (en) * | 1985-05-28 | 1992-12-15 |
-
1975
- 1975-12-26 JP JP50157140A patent/JPS5913510B2/en not_active Expired
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57154129A (en) * | 1981-03-16 | 1982-09-22 | Otsuka Pharmaceut Co Ltd | Cardiotonic drug |
JPH0153248B2 (en) * | 1981-03-16 | 1989-11-13 | Otsuka Pharma Co Ltd | |
JPS60208965A (en) * | 1983-12-24 | 1985-10-21 | Tanabe Seiyaku Co Ltd | Novel carbostyril derivative and its preparation |
JPS6354362A (en) * | 1983-12-24 | 1988-03-08 | Tanabe Seiyaku Co Ltd | Carbostyril compound |
USRE33024E (en) * | 1983-12-24 | 1989-08-15 | Tanabe Seiyaku Co. Ltd. | Bronchodilating 8-hydroxy-5-(1R)-1-hydroxy-2-(N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)-amino)ethyl) carbostyril and intermediates thereof |
JPH0446950B2 (en) * | 1983-12-24 | 1992-07-31 | Tanabe Seiyaku Co | |
US6949568B2 (en) | 2001-11-13 | 2005-09-27 | Theravance, Inc. | Aryl aniline β2 adrenergic receptor agonists |
US6670376B1 (en) | 2001-11-13 | 2003-12-30 | Theravance, Inc. | Aryl aniline β2 adrenergic receptor agonists |
US6653323B2 (en) | 2001-11-13 | 2003-11-25 | Theravance, Inc. | Aryl aniline β2 adrenergic receptor agonists |
US7125892B2 (en) | 2001-11-13 | 2006-10-24 | Theravance, Inc. | Aryl aniline β2 adrenergic receptor agonists |
US7582765B2 (en) | 2003-05-08 | 2009-09-01 | Theravance, Inc. | Aryl aniline β2 adrenergic receptor agonists |
US7399863B2 (en) | 2003-09-22 | 2008-07-15 | Theravance, Inc. | Amino-substituted ethylamino β2 adrenergic receptor agonists |
US7964730B2 (en) | 2003-09-22 | 2011-06-21 | Theravance, Inc. | Amino-substituted ethylamino β2 adrenergic receptor agonists |
US7622467B2 (en) | 2004-01-12 | 2009-11-24 | Theravance, Inc. | Aryl aniline derivatives as β2 adrenergic receptor agonists |
US7994165B2 (en) | 2004-01-12 | 2011-08-09 | Theravance, Inc. | Aryl aniline derivatives as β2 adrenergic receptor agonists |
US7402673B2 (en) | 2004-06-03 | 2008-07-22 | Theravance, Inc. | Diamine β2 adrenergic receptor agonists |
US7566785B2 (en) | 2004-09-10 | 2009-07-28 | Theravance, Inc. | Amidine substituted aryl aniline compounds |
Also Published As
Publication number | Publication date |
---|---|
JPS5913510B2 (en) | 1984-03-30 |
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