JPS51149234A - Process for preparation of novel carboxylic acid dervatives - Google Patents

Process for preparation of novel carboxylic acid dervatives

Info

Publication number
JPS51149234A
JPS51149234A JP50074014A JP7401475A JPS51149234A JP S51149234 A JPS51149234 A JP S51149234A JP 50074014 A JP50074014 A JP 50074014A JP 7401475 A JP7401475 A JP 7401475A JP S51149234 A JPS51149234 A JP S51149234A
Authority
JP
Japan
Prior art keywords
carboxylic acid
preparation
novel carboxylic
dervatives
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP50074014A
Other languages
Japanese (ja)
Other versions
JPS549183B2 (en
Inventor
Hiroshi Murai
Katsuya Ohata
Hiroshi Enomoto
Shoichi Jokai
Mitsuhiro Maehara
Katsuhide Saito
Takayuki Ozaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Priority to JP50074014A priority Critical patent/JPS51149234A/en
Priority to PT65159A priority patent/PT65159B/en
Priority to GB22541/76A priority patent/GB1493756A/en
Priority to DE19762624569 priority patent/DE2624569A1/en
Priority to US05/692,878 priority patent/US4064252A/en
Priority to CH754776A priority patent/CH622492A5/de
Priority to NLAANVRAGE7606380,A priority patent/NL169584C/en
Priority to AT431776A priority patent/AT345797B/en
Priority to LU75170A priority patent/LU75170A1/xx
Priority to ES448932A priority patent/ES448932A1/en
Priority to CA254,950A priority patent/CA1056839A/en
Priority to SE7606857A priority patent/SE429962B/en
Priority to DK269876A priority patent/DK146363C/en
Priority to FR7618294A priority patent/FR2314710A1/en
Priority to ZA763612A priority patent/ZA763612B/en
Priority to BE168031A priority patent/BE843075A/en
Priority to AR263657A priority patent/AR221468A1/en
Priority to DD193421A priority patent/DD125654A5/xx
Priority to AR265750A priority patent/AR221324A1/en
Publication of JPS51149234A publication Critical patent/JPS51149234A/en
Priority to US05/762,021 priority patent/US4162331A/en
Priority to US05/761,721 priority patent/US4094991A/en
Priority to AR270411A priority patent/AR219931A1/en
Publication of JPS549183B2 publication Critical patent/JPS549183B2/ja
Priority to CH299080A priority patent/CH623805A5/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/06—Aluminium compounds
    • C07F5/069—Aluminium compounds without C-aluminium linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: Carboxylic acid derivatives of formula I[where R1 is OR'(R' is H, OH, lower alkyl, etc.) or formula II(R'', R''', are H, lower alkyl, allyl, aralkyl or hydroixyalkyl, R'' and R''' together may form heterocyclic ring such as Yis H, hologen, lower alkyl, OH, aralkyloxy, etc.].
COPYRIGHT: (C)1976,JPO&Japio
JP50074014A 1975-06-17 1975-06-17 Process for preparation of novel carboxylic acid dervatives Granted JPS51149234A (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
JP50074014A JPS51149234A (en) 1975-06-17 1975-06-17 Process for preparation of novel carboxylic acid dervatives
PT65159A PT65159B (en) 1975-06-17 1976-05-31 New carboxylic acid derivatives and their production
GB22541/76A GB1493756A (en) 1975-06-17 1976-06-01 Carboxylic acid derivatives and their production
DE19762624569 DE2624569A1 (en) 1975-06-17 1976-06-01 NEW CARBONIC ACID DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION
US05/692,878 US4064252A (en) 1975-06-17 1976-06-04 Substituted N-(carboxymethyl)-3-aminopropan-2-ol derivatives
CH754776A CH622492A5 (en) 1975-06-17 1976-06-14
NLAANVRAGE7606380,A NL169584C (en) 1975-06-17 1976-06-14 PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE 1-PHENOXY-3-CARBONYL METHYLAMINO-2-OXYPROPANES IN A METHOD KNOWN FOR ANALOGIC COMPOUNDS.
AT431776A AT345797B (en) 1975-06-17 1976-06-14 METHOD FOR THE PRODUCTION OF NEW N, N-DISUBSTITUTED AMINO ACETIC DERIVATIVES
LU75170A LU75170A1 (en) 1975-06-17 1976-06-15
SE7606857A SE429962B (en) 1975-06-17 1976-06-16 SET TO MAKE NEW CARBOXYLIC ACID DERIVATIVES AND CERTAIN SALTS THEREOF, WHICH DERIVATIVES AND SALTS HAVE SERUM LIPID-UNDERSTANDING PROPERTIES
CA254,950A CA1056839A (en) 1975-06-17 1976-06-16 Carboxylic acid derivatives and their production
ES448932A ES448932A1 (en) 1975-06-17 1976-06-16 Process for preparation of novel carboxylic acid dervatives
DK269876A DK146363C (en) 1975-06-17 1976-06-16 ANALOGY PROCEDURE FOR THE PREPARATION OF N, N-DISUBSTITUTED GLYCIN DERIVATIVES
FR7618294A FR2314710A1 (en) 1975-06-17 1976-06-16 PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID DERIVATIVES, NEW PRODUCTS THUS OBTAINED AND THEIR USE FOR THE PREVENTION OR TREATMENT OF ARTERIOSCLEROSIS
ZA763612A ZA763612B (en) 1975-06-17 1976-06-17 New carboxylic acid derivatives and their production
BE168031A BE843075A (en) 1975-06-17 1976-06-17 NEW CARBOXYLIC ACIDS AND THEIR PRODUCTION FROM MORPHOLINONES
AR263657A AR221468A1 (en) 1975-06-17 1976-06-17 A PROCEDURE FOR PREPARING NEW DERIVATIVES OF 1-PHENOXY-3- (N-PHENYL (CARBAMOYL METHYL) -AMINO) -2-PROPANOL
DD193421A DD125654A5 (en) 1975-06-17 1976-06-17
AR265750A AR221324A1 (en) 1975-06-17 1976-12-07 PREPARATION METHOD FOR NEW DERIVATIVES OF 1-PHENOXI-3-N-PHENYLAMINO-N-CARBOALQUIL (CARBOALQUILOXIALQUILO) -2-PROPANOL
US05/762,021 US4162331A (en) 1975-06-17 1977-01-24 Substituted N-(carboxymethyl)-3-aminopropan-2-ol derivatives
US05/761,721 US4094991A (en) 1975-06-17 1977-01-24 Substituted n-(carboxymethyl)-3-aminopropan-2-ol derivatives
AR270411A AR219931A1 (en) 1975-06-17 1977-12-19 PROCEDURE FOR PREPARING NEW DERIVATIVES OF PHENOXI-3- (N-PHENYLAMINE ALCOXICARBONIL) -2-PROPANOL AND ITS ALKALINE, ALKALINE TERRAIN AND ALUMINUM METAL SALTS
CH299080A CH623805A5 (en) 1975-06-17 1980-04-17

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50074014A JPS51149234A (en) 1975-06-17 1975-06-17 Process for preparation of novel carboxylic acid dervatives

Publications (2)

Publication Number Publication Date
JPS51149234A true JPS51149234A (en) 1976-12-22
JPS549183B2 JPS549183B2 (en) 1979-04-21

Family

ID=13534807

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50074014A Granted JPS51149234A (en) 1975-06-17 1975-06-17 Process for preparation of novel carboxylic acid dervatives

Country Status (8)

Country Link
JP (1) JPS51149234A (en)
AT (1) AT345797B (en)
BE (1) BE843075A (en)
DD (1) DD125654A5 (en)
ES (1) ES448932A1 (en)
LU (1) LU75170A1 (en)
PT (1) PT65159B (en)
ZA (1) ZA763612B (en)

Also Published As

Publication number Publication date
DD125654A5 (en) 1977-05-11
AT345797B (en) 1978-10-10
ATA431776A (en) 1978-02-15
BE843075A (en) 1976-10-18
JPS549183B2 (en) 1979-04-21
PT65159B (en) 1977-10-13
LU75170A1 (en) 1977-01-26
PT65159A (en) 1976-06-01
ZA763612B (en) 1977-05-25
ES448932A1 (en) 1977-07-01

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