JPS5077355A - - Google Patents
Info
- Publication number
- JPS5077355A JPS5077355A JP49116992A JP11699274A JPS5077355A JP S5077355 A JPS5077355 A JP S5077355A JP 49116992 A JP49116992 A JP 49116992A JP 11699274 A JP11699274 A JP 11699274A JP S5077355 A JPS5077355 A JP S5077355A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40596473A | 1973-10-12 | 1973-10-12 | |
| US05/492,943 US4006180A (en) | 1973-10-12 | 1974-07-31 | [1,3-Dihydroxy-2-substituted and 2,2-disubstituted-indanyloxy(or thio)]alkanoic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5077355A true JPS5077355A (ja) | 1975-06-24 |
Family
ID=27019306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP49116992A Pending JPS5077355A (ja) | 1973-10-12 | 1974-10-11 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4006180A (ja) |
| JP (1) | JPS5077355A (ja) |
| DE (1) | DE2448393A1 (ja) |
| DK (1) | DK506774A (ja) |
| FR (1) | FR2247217B1 (ja) |
| GB (1) | GB1480239A (ja) |
| NL (1) | NL7412830A (ja) |
| SE (1) | SE7412047L (ja) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5001255A (en) * | 1984-12-04 | 1991-03-19 | Sandoz Pharm. Corp. | Idene analogs of mevalonolactone and derivatives thereof |
| US20060258581A1 (en) * | 2001-11-21 | 2006-11-16 | Reed John C | Methods and composition for derepressions of IAP-inhibited caspase |
| CN101029080A (zh) * | 2001-11-21 | 2007-09-05 | 伯纳姆研究院 | 用于对iap抑制卡斯蛋白酶进行去阻遏的方法及组合物 |
| US20050119176A1 (en) * | 2001-11-21 | 2005-06-02 | The Burnham Institute | Methods and compositions for derepression of IAP-inhibited caspase |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6858614B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenolic guanidine sodium channel blockers |
| US20060089400A1 (en) * | 2002-05-03 | 2006-04-27 | The Vernalis Group Of Companies | Novel spiro ketone and carboxylic acid derivatives as specific inhibitors for (po3h2) ser/(po3h2)thr-pro-specific peptidyl-prolylcis/trans-isomerases |
| US6903105B2 (en) * | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US20050090505A1 (en) * | 2003-08-18 | 2005-04-28 | Johnson Michael R. | Methods of reducing risk of infection from pathogens |
| US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| US20090253714A1 (en) * | 2003-08-20 | 2009-10-08 | Johnson Michael R | Methods of reducing risk of infection from pathogens |
| US20110183358A1 (en) * | 2005-03-17 | 2011-07-28 | The Burnham Institute | Methods and compositions for derepression of iap-inhibited caspase |
| WO2006102068A2 (en) * | 2005-03-17 | 2006-09-28 | The Burnham Institute | Methods and compositions for derepression of iap-inhibited caspase |
| US20070003535A1 (en) * | 2005-03-17 | 2007-01-04 | Reed John C | Methods and compositions for derepression of IAP-inhibited caspase |
| US20070021439A1 (en) * | 2005-07-25 | 2007-01-25 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers |
| US20090043099A1 (en) * | 2006-03-17 | 2009-02-12 | The Burnham Institute | Methods and compositions for derepression of IAP-inhibited caspase |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| RU2018138195A (ru) | 2012-12-17 | 2018-12-18 | Пэрион Сайенсиз, Инк. | Соединения 3,5-диамино-6-хлор-n-(n-(4- фенилбутил)карбамимидоил)пиразин-2-карбоксамида |
| PE20151054A1 (es) | 2012-12-17 | 2015-08-07 | Parion Sciences Inc | Derivados de cloro-pirazin carboxamida con actividad bloqueadora sobre los canales de sodio epiteliales |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1498459A (ja) * | 1965-07-30 | 1968-01-08 | ||
| US3668241A (en) * | 1968-11-25 | 1972-06-06 | Merck & Co Inc | Substituted 1-oxoinden-5-yloxy alkanoic acids |
| US3704314A (en) * | 1968-11-25 | 1972-11-28 | Merck & Co Inc | (1-oxo-2-alkylideneindanyloxy) and (1-oxo - 2 - alkylideneindanylthio) alkanoic acids |
| US3776944A (en) * | 1971-09-16 | 1973-12-04 | Warner Lambert Co | Tetraloneoxy acetic acids and esters thereof |
| US3906032A (en) * | 1972-11-10 | 1975-09-16 | Squibb & Sons Inc | Dihydroxy-tetrahydronaphthyoxyisobutyric acids and alkyl esters and salts thereof |
-
1974
- 1974-07-31 US US05/492,943 patent/US4006180A/en not_active Expired - Lifetime
- 1974-09-25 SE SE7412047A patent/SE7412047L/xx unknown
- 1974-09-26 DK DK506774A patent/DK506774A/da unknown
- 1974-09-27 NL NL7412830A patent/NL7412830A/xx not_active Application Discontinuation
- 1974-10-07 GB GB43375/74A patent/GB1480239A/en not_active Expired
- 1974-10-08 FR FR7433812A patent/FR2247217B1/fr not_active Expired
- 1974-10-10 DE DE19742448393 patent/DE2448393A1/de active Pending
- 1974-10-11 JP JP49116992A patent/JPS5077355A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2247217B1 (ja) | 1978-02-03 |
| GB1480239A (en) | 1977-07-20 |
| DE2448393A1 (de) | 1975-04-17 |
| FR2247217A1 (ja) | 1975-05-09 |
| DK506774A (ja) | 1975-06-09 |
| US4006180A (en) | 1977-02-01 |
| NL7412830A (nl) | 1975-04-15 |
| SE7412047L (ja) | 1975-04-14 |