JPS5013371A - - Google Patents
Info
- Publication number
- JPS5013371A JPS5013371A JP49048871A JP4887174A JPS5013371A JP S5013371 A JPS5013371 A JP S5013371A JP 49048871 A JP49048871 A JP 49048871A JP 4887174 A JP4887174 A JP 4887174A JP S5013371 A JPS5013371 A JP S5013371A
- Authority
- JP
- Japan
- Prior art keywords
- cyclised
- acetic acids
- compounds
- indenyl acetic
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Rheumatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Cyclised benzylidene indenyl acetic acids and pharmaceutically acceptable salts, amides and esters thereof. The cyclised benzylidene indenyl acetic acids have anti-inflammatory, anti-pyretic and analgesic activity. The invention also includes methods for the preparation of these compounds, pharmaceutical compositions and methods of treating inflammation by administering these particular compounds to patients.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US357314A US3867433A (en) | 1973-05-04 | 1973-05-04 | Cyclopenta{8 j,k{9 -phenanthrene-4-acetic acids and related compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5013371A true JPS5013371A (en) | 1975-02-12 |
Family
ID=23405100
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP49048871A Pending JPS5013371A (en) | 1973-05-04 | 1974-05-02 |
Country Status (7)
Country | Link |
---|---|
US (1) | US3867433A (en) |
JP (1) | JPS5013371A (en) |
CH (1) | CH592597A5 (en) |
DE (1) | DE2421541A1 (en) |
FR (1) | FR2236488B1 (en) |
GB (1) | GB1453885A (en) |
NL (1) | NL7405118A (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4692545A (en) * | 1986-12-12 | 1987-09-08 | Stauffer Chemical Company | Method for preparation of mercaptobenzoates |
US4704467A (en) * | 1986-12-12 | 1987-11-03 | Stauffer Chemical Company | Method for preparation of mercaptobenzoates |
MX168606B (en) * | 1986-12-12 | 1993-06-01 | Ici American Ine | METHOD FOR THE PREPARATION OF MERCAPTOBENZOATES. |
GB9714302D0 (en) | 1997-07-07 | 1997-09-10 | Rhone Poulenc Agrochimie | Process |
US6180629B1 (en) | 1998-08-14 | 2001-01-30 | Cell Pathways, Inc. | [4,5]-Fused-1,3-disubstituted-1,2-diazine-6-one derivatives with nitrogen containing substitutents in position one for the treatment of neoplasia |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB330916A (en) * | 1929-02-01 | 1930-06-19 | Ig Farbenindustrie Ag | Manufacture of aryl-acetic acids and substitution products thereof |
US3766259A (en) * | 1970-05-01 | 1973-10-16 | Merck & Co Inc | Preparation of 1-aryl-3-indenyl acetic acids |
US3654349A (en) * | 1970-05-01 | 1972-04-04 | Merck & Co Inc | Substituted indenyl acetic acids |
-
1973
- 1973-05-04 US US357314A patent/US3867433A/en not_active Expired - Lifetime
-
1974
- 1974-04-16 NL NL7405118A patent/NL7405118A/xx not_active Application Discontinuation
- 1974-04-26 CH CH576874A patent/CH592597A5/xx not_active IP Right Cessation
- 1974-04-29 GB GB1857874A patent/GB1453885A/en not_active Expired
- 1974-05-02 JP JP49048871A patent/JPS5013371A/ja active Pending
- 1974-05-02 FR FR7415225A patent/FR2236488B1/fr not_active Expired
- 1974-05-03 DE DE2421541A patent/DE2421541A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
FR2236488A1 (en) | 1975-02-07 |
DE2421541A1 (en) | 1974-11-21 |
GB1453885A (en) | 1976-10-27 |
US3867433A (en) | 1975-02-18 |
NL7405118A (en) | 1974-11-06 |
FR2236488B1 (en) | 1978-02-03 |
CH592597A5 (en) | 1977-10-31 |
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