JPS4956992A - - Google Patents

Info

Publication number
JPS4956992A
JPS4956992A JP48093220A JP9322073A JPS4956992A JP S4956992 A JPS4956992 A JP S4956992A JP 48093220 A JP48093220 A JP 48093220A JP 9322073 A JP9322073 A JP 9322073A JP S4956992 A JPS4956992 A JP S4956992A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP48093220A
Other languages
Japanese (ja)
Other versions
JPS5911589B2 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4956992A publication Critical patent/JPS4956992A/ja
Publication of JPS5911589B2 publication Critical patent/JPS5911589B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP48093220A 1972-08-21 1973-08-20 Method for producing benzodiazepine derivatives Expired JPS5911589B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28221772A 1972-08-21 1972-08-21
US35981473A 1973-05-14 1973-05-14
US359814 1973-05-14
US282217 1994-07-28

Publications (2)

Publication Number Publication Date
JPS4956992A true JPS4956992A (en) 1974-06-03
JPS5911589B2 JPS5911589B2 (en) 1984-03-16

Family

ID=26961312

Family Applications (1)

Application Number Title Priority Date Filing Date
JP48093220A Expired JPS5911589B2 (en) 1972-08-21 1973-08-20 Method for producing benzodiazepine derivatives

Country Status (24)

Country Link
JP (1) JPS5911589B2 (en)
AR (1) AR198108A1 (en)
AT (1) AT341527B (en)
AU (1) AU472777B2 (en)
CA (1) CA1012535A (en)
CH (1) CH578544A5 (en)
DD (1) DD107040A5 (en)
DE (1) DE2340159A1 (en)
DK (1) DK155326C (en)
ES (1) ES418014A1 (en)
FI (1) FI57939C (en)
FR (1) FR2197003B1 (en)
GB (1) GB1392681A (en)
HU (1) HU170153B (en)
IE (1) IE38091B1 (en)
IL (1) IL42947A (en)
LU (1) LU68269A1 (en)
NL (1) NL179582C (en)
NO (1) NO139481C (en)
PH (1) PH13640A (en)
PL (1) PL99162B1 (en)
SE (1) SE408302B (en)
SU (1) SU550980A3 (en)
YU (1) YU219873A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5334792A (en) * 1976-09-13 1978-03-31 Scherico Ltd Production of 1*44 benzodiazepines and 1*44 benzodiazepinee22ones

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113149915B (en) * 2021-03-01 2024-03-15 中国科学院成都有机化学有限公司 Method for synthesizing clonazepam compound
CN116023342B (en) * 2021-10-26 2024-06-25 江苏昱林生物科技有限公司 Preparation method of high-purity clonazepam

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2016084A1 (en) * 1969-10-16 1971-04-29 CRC Compagnia dl Ricerca Chimica S A, Chiasso(Schweiz) 1,4-benzodiazepines prepn

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1136709B (en) * 1959-12-10 1962-09-20 Hoffmann La Roche Process for the preparation of 2-oxo-1, 2-dihydro-1, 4-benzodiazepines
BE785962A (en) * 1971-07-08 1973-01-08 Hoffmann La Roche PROCESS FOR THE PREPARATION OF BENZODIAZEPINE DERIVATIVES

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2016084A1 (en) * 1969-10-16 1971-04-29 CRC Compagnia dl Ricerca Chimica S A, Chiasso(Schweiz) 1,4-benzodiazepines prepn

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5334792A (en) * 1976-09-13 1978-03-31 Scherico Ltd Production of 1*44 benzodiazepines and 1*44 benzodiazepinee22ones
JPS6214552B2 (en) * 1976-09-13 1987-04-02 Scherico Ltd

Also Published As

Publication number Publication date
NO139481C (en) 1979-03-21
ATA720773A (en) 1977-06-15
JPS5911589B2 (en) 1984-03-16
LU68269A1 (en) 1975-05-21
DE2340159C2 (en) 1989-01-19
NO139481B (en) 1978-12-11
AR198108A1 (en) 1974-05-31
NL179582B (en) 1986-05-01
FI57939B (en) 1980-07-31
IL42947A0 (en) 1973-11-28
GB1392681A (en) 1975-04-30
DK155326B (en) 1989-03-28
ES418014A1 (en) 1976-03-16
FR2197003A1 (en) 1974-03-22
CA1012535A (en) 1977-06-21
SE408302B (en) 1979-06-05
FI57939C (en) 1980-11-10
HU170153B (en) 1977-04-28
PL99162B1 (en) 1978-06-30
AU5918073A (en) 1975-02-13
DD107040A5 (en) 1974-07-12
AT341527B (en) 1978-02-10
IL42947A (en) 1977-01-31
YU219873A (en) 1982-06-30
IE38091B1 (en) 1977-12-21
AU472777B2 (en) 1976-06-03
CH578544A5 (en) 1976-08-13
NL7311507A (en) 1974-02-25
DK155326C (en) 1989-08-14
SU550980A3 (en) 1977-03-15
DE2340159A1 (en) 1974-03-07
IE38091L (en) 1974-02-21
FR2197003B1 (en) 1978-01-13
NL179582C (en) 1986-10-01
PH13640A (en) 1980-08-18

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