JPS4943990A - - Google Patents

Info

Publication number
JPS4943990A
JPS4943990A JP48082493A JP8249373A JPS4943990A JP S4943990 A JPS4943990 A JP S4943990A JP 48082493 A JP48082493 A JP 48082493A JP 8249373 A JP8249373 A JP 8249373A JP S4943990 A JPS4943990 A JP S4943990A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP48082493A
Other languages
Japanese (ja)
Other versions
JPS5331158B2 (US20020167097A1-20021114-C00005.png
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4943990A publication Critical patent/JPS4943990A/ja
Publication of JPS5331158B2 publication Critical patent/JPS5331158B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP8249373A 1972-07-20 1973-07-20 Expired JPS5331158B2 (US20020167097A1-20021114-C00005.png)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2235597A DE2235597A1 (de) 1972-07-20 1972-07-20 1-eckige klammer auf 3-(5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl eckige klammer zu -piperazin-derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
JPS4943990A true JPS4943990A (US20020167097A1-20021114-C00005.png) 1974-04-25
JPS5331158B2 JPS5331158B2 (US20020167097A1-20021114-C00005.png) 1978-08-31

Family

ID=5851155

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8249373A Expired JPS5331158B2 (US20020167097A1-20021114-C00005.png) 1972-07-20 1973-07-20

Country Status (14)

Country Link
US (1) US3947446A (US20020167097A1-20021114-C00005.png)
JP (1) JPS5331158B2 (US20020167097A1-20021114-C00005.png)
AR (1) AR196775A1 (US20020167097A1-20021114-C00005.png)
AT (1) AT330188B (US20020167097A1-20021114-C00005.png)
CA (1) CA1003836A (US20020167097A1-20021114-C00005.png)
CH (2) CH583721A5 (US20020167097A1-20021114-C00005.png)
DD (1) DD106842A5 (US20020167097A1-20021114-C00005.png)
DE (1) DE2235597A1 (US20020167097A1-20021114-C00005.png)
ES (1) ES416929A1 (US20020167097A1-20021114-C00005.png)
FR (1) FR2193598B1 (US20020167097A1-20021114-C00005.png)
GB (1) GB1376588A (US20020167097A1-20021114-C00005.png)
HU (1) HU165887B (US20020167097A1-20021114-C00005.png)
NL (1) NL149168B (US20020167097A1-20021114-C00005.png)
ZA (1) ZA734811B (US20020167097A1-20021114-C00005.png)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL175059C (nl) * 1974-02-23 Boehringer Mannheim Gmbh Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.
DE2658762A1 (de) * 1976-12-24 1978-06-29 Hoechst Ag Neue o-alkylierte oxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB1583372A (en) * 1977-04-04 1981-01-28 Degussa 1-(3-(3,4,5-trimethoxyphenoxy)-2-hydroxypropyl)-4-aryl piperazine derivatives
US4101723A (en) * 1977-04-05 1978-07-18 E. R. Squibb & Sons, Inc. Substituted piperazinopropanols
US4259327A (en) * 1979-04-02 1981-03-31 Merck & Co., Inc. Substituted aminoalkoxypyridines, compositions and use thereof
US4255426A (en) * 1979-07-09 1981-03-10 Pfizer Inc. 1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted-piperazines and piperidines
DE3918542A1 (de) * 1989-06-07 1990-12-13 Boehringer Mannheim Gmbh Hydroxylierte 1-phenyl-4-(3-(napthth-1-yl-oxy)-2-hydroxy -propyl)-piperazine, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
FR2658818B1 (fr) * 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
IT1255178B (it) * 1992-06-26 1995-10-20 Pierrel Spa N(eter0)-aril-n(etero)-tetralinalchil piperazine aventi attivita' serotoninergica,dopaminergica e adrenergica
CA2332275A1 (en) * 1998-05-14 1999-11-18 Zoltan Tamas Nagy Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
EP1425261A2 (de) * 2001-08-31 2004-06-09 Bayer Chemicals AG Verfahren zur herstellung von 4-amino-1-naphtholethern

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1317034A (en) * 1970-11-06 1973-05-16 Pfizer Ltd 1-2-hydroxy-3-phenoxy- or -phenylthiopropyl-piperazine derivatives

Also Published As

Publication number Publication date
US3947446A (en) 1976-03-30
FR2193598A1 (US20020167097A1-20021114-C00005.png) 1974-02-22
DD106842A5 (US20020167097A1-20021114-C00005.png) 1974-07-05
FR2193598B1 (US20020167097A1-20021114-C00005.png) 1977-07-15
HU165887B (US20020167097A1-20021114-C00005.png) 1974-12-28
AR196775A1 (es) 1974-02-19
ES416929A1 (es) 1976-03-01
CH583722A5 (US20020167097A1-20021114-C00005.png) 1977-01-14
AT330188B (de) 1976-06-25
ZA734811B (en) 1974-07-31
NL149168B (nl) 1976-04-15
CA1003836A (en) 1977-01-18
DE2235597A1 (de) 1974-01-31
NL7310041A (US20020167097A1-20021114-C00005.png) 1974-01-22
GB1376588A (en) 1974-12-04
CH583721A5 (US20020167097A1-20021114-C00005.png) 1977-01-14
JPS5331158B2 (US20020167097A1-20021114-C00005.png) 1978-08-31
ATA636673A (de) 1975-09-15

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