JPH1183726A - Examination apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an apparatus for outputting the past processing results and the advance progress up to the present at a glance during examination, by simultaneously displaying the image data of a certain specimen, the examination advance progress of a predetermined number of specimens to be processed, and the examination result up to that time on one screen during the examination of the certain specimen. SOLUTION: At a time of the start of examination, the setting of an examination condition at every cassette, the setting of an examination condition at every slide, the setting of the examination condition of a system and the start of examination are designated. As the output from the system of a leucocyte automatic classifying apparatus, at first, there is intermediate classifying data. The automatically classified result data of the system, that is, the image of automatically classified leucocyte cells, automatically classified results, the image of erythrocytes and totalized results are outputted to an image at every slide. An operator performs review on the basis of these results. As final classified data, the classified result data after the operator performs review, concretely, classified data at every blood corpuscle kind, operator's comment or the like are outputted.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an apparatus for testing a blood sample or the like.

[0002]

2. Description of the Related Art Conventionally, as an apparatus for testing a blood sample, a plurality of specimens stored in a cassette are automatically conveyed to an imaging section, and the specimens are imaged by mounting the specimens one by one on the imaging section. There is an automatic blood cell analyzer that performs white blood cell classification, red blood cell morphological analysis, platelet count, and reticulocyte count. This automatic blood cell analyzer automatically prints test results on a printer, records the results on a floppy disk,
U. Also, up to which sample (specimen) of the planned number of cassettes the processing has progressed, and the progress of the inspection processing are displayed on a screen different from the image under inspection. Further, the processing state of the cassette that collectively stores the samples and the sample processing state are separate screens, and are switched and displayed by key operation.

[0003]

In the conventional blood sample testing apparatus described above, the past processing results are described only in the printer paper, floppy disk, or the transmitted host CPU, and the progress of the processing up to the present is described. In order to check, it is necessary to press the key to switch to another screen.In addition, since the cassette processing state and the sample processing state can not be viewed at once There was a problem that it was difficult to check the progress.

SUMMARY OF THE INVENTION The present invention has been made in view of the above problems, and has as its object to provide an inspection apparatus that allows the user to know at a glance the result of past processing and the progress of progress up to the present during inspection.

[0005]

According to a first aspect of the present invention, there is provided an inspection apparatus in which a specimen stored in a cassette is sequentially imaged by an imaging section, and the specimen is automatically analyzed. In an apparatus for displaying an image of a sample that has been taken, an analysis result and an image of the taken sample are stored, and a display progress display unit for a sample to be processed, a sample image information display unit for the test, And a result display unit.

[0006] In this test apparatus, during the test of a certain sample,
The image information of the sample, the progress of the test for the number of samples to be processed in advance, and the test results up to that time are simultaneously displayed on one screen. The inspection device according to claim 2 is the inspection device according to claim 1, wherein the inspection progress display unit includes:
The cassette number is set on one side of the matrix, and the sample number of each cassette is set on the other side of the matrix, and displayed on the matrix.
Since the progress of the test of the sample is displayed in a matrix, the processing status of each sample can be checked at a glance.

According to a third aspect of the present invention, in the inspection apparatus according to the second aspect, the inspection progress matrix display section specifies and inputs an arbitrary point on the matrix display to specify a sample. The setting relating to the sample can be changed. By specifying an arbitrary sample, setting conditions relating to the sample are displayed, and for example, the count number, the method of smearing the sample, and the like can be changed.

According to a fourth aspect of the present invention, in the inspection apparatus according to the second or third aspect, the inspection progress progress matrix display section displays the progress information in a distinguishing manner, for example, by color coding according to a processing situation. I do. Because they are distinguished,
You can see at a glance what the processing status is. According to a fifth aspect of the present invention, in the inspection apparatus according to the first aspect, the sample image information display unit enables the change of the sample number and the test condition that can be changed at that time. In this test device, for example, when the planned count of a certain cell is planned to be 100 and the current count is 65, the planned number can be changed to 80. However, it has already counted 65 and cannot change the setting to 50.

According to a sixth aspect of the present invention, in the inspection apparatus according to the first aspect, the inspection result display section can perform a re-inspection by designating a sample in the inspection result. When an arbitrary sample is designated from the test results, a series of cell images of the sample is displayed, and the operator can visually inspect the sample again.

[0010]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, the present invention will be described in more detail with reference to embodiments. FIG. 1 is a block diagram showing a configuration of an automatic leukocyte classification apparatus according to an embodiment of the present invention. The automatic white blood cell classification apparatus of this embodiment includes an automatic microscope control unit 1, an image processing unit 2 for blood cell classification, and an external device 3. The external device 3 is a monitor, a keyboard, a mouse, a dedicated keyboard, a printer, or the like. The image display unit 4 for the batch review is a computer dedicated to the review, and by attaching the portable medium 25,
Each image can be reproduced like a monitor.

The automatic microscope control unit 1 includes a camera 11 for imaging a sample, and a stage Z for raising and lowering a lens of the camera 11.
12. Stage X holding the sample and moving it back and forth, left and right,
Optical system 10 including Y13 and MC unit 14 for mechanical control
And an MS section 15 for controlling the camera 11, a cassette transport section 16, an MC section power supply 17, a lamp power supply 18, and a camera power supply 19.

The image processing section 2 includes an FE section 21 which is an image feature extraction / processing section, an FE section power supply 22, a PC section 23 which is a system control computer, and a PC section power supply 24.
, A portable medium 25, and an entire power supply 26. In this automatic leukocyte classification apparatus, an input to the system is that a slide glass (specimen) on which blood is smeared as a test object (sample), that is, a specimen, is set in a dedicated cassette and set in the system. Numbers 1 to 15 (15) are assigned to the special cassettes, and the numbers (called cassette numbers) are read by sensors,
It is memorized. Also, the slide storage units in one dedicated cassette are numbered 1 to 20, and the numbers correspond to the positions of the shelves of the slide storage units of the cassette (referred to as slide numbers).

At the start of the inspection, an instruction for the inspection is issued. The inspection instruction includes setting of inspection conditions for each cassette, setting of inspection conditions for each slide, setting of inspection conditions of the system,
And an instruction to start the inspection. Each instruction is input to the system by transmission from a full keyboard, a mouse, a dedicated keyboard, and a host CPU. After the system is automatically classified, the operator performs a retest (review) based on the classification result, and inputs the cell type of the designated cell to the system. The input method uses a mouse or a dedicated keyboard. This review is described in more detail below.

In this automatic leukocyte classification apparatus, the output from the system first includes intermediate classification data. The automatic classification result data of the system, that is, the image of the white blood cell automatically classified, the automatic classification result, the image of the red blood cell, and the total result are output to the screen for each slide. The operator
A retest (review) is performed based on the results. As final classification data, classification result data after the operator has performed a review, specifically, classification results for each blood cell type, comments from the operator, and the like are output.

FIG. 2 shows a display screen at the time of the "count" operation of the automatic leukocyte classification apparatus of the embodiment. The display screen includes a cassette / slide information display section 31, a count cell image display section 32, and a count log display section 33.
In addition, a slide operation input selection display unit 34 and a cassette operation input selection display unit 35 are arranged. The cassette / slide display unit 31 includes a matrix display unit 31a and a processing status color display unit 31b. Matrix display section 31
“a” takes the cassette numbers 1 to 15 vertically and the slide numbers 1 to 20 horizontally, and displays the processing status of all slides in color. The colors correspond to unprocessed, no slide, counting, reviewing, processed, counting completed, and error in the processing state, and the color display of each status on the processing status color display section 31b and each slide display on the matrix display section 31a are as follows. , In the colors shown in FIG.

The counting cell image display section 32 displays information during counting and classified cell images. Specifically, in addition to the cell image, cassette numbers 1 to 15 and
The slide number from 1 to 20, the PID of the sample being counted, and the number of counts, ie, the WBC being counted
The number and the set WBC number are displayed. Count log display section 33
Shows a count log of the slides for which counting has been completed. If the value deviates from the set normal value range, PI
"." Is displayed to the right of D and its blood cell type item.

The delete (button) 36 deletes the selected log data. It is enabled when the system is ready, and if you select it, a message box asking if you want to execute it will be displayed.If you select "Yes", the displayed message box will be erased and the selected log data will be deleted. . If "No" is selected, the displayed message disappears and the display returns to the original display. When the print (button) 37 is pressed, the count log data is printed out by the printer.

The count (button) of the slide operation selection button display section 34 is a button for starting the count operation. When this button is pressed, the cassette is automatically loaded, and the slide count operation in the cassette is performed. To start. During the counting operation, the operation of this button is prohibited (displayed in gray). The pause (button) is a button for temporarily stopping the count operation. When this button is pressed, the current count operation is temporarily stopped. Then, when the pause button is pressed again, the counting operation is started from the point where the pause was made. This button is prohibited (displayed in gray) except during the counting operation.

The stop (button) is a button for stopping the counting operation. When this button is pressed, the current mechanical operation or counting operation is stopped. Then, press the necessary buttons according to the desired operation. When the count button is pressed, the counting operation is resumed from the point where it was interrupted.
Pressing the recount button resets the count result so far and starts counting again. When you press the next sample,
Cancels the count operation of the current slide and starts the count operation of the next sample. Pressing the next cassette cancels the count operation of the current cassette,
The count operation of the next cassette is started. When the user presses the eject button, the current cassette counting operation is canceled, the cassette is ejected, and the system is brought into a ready state. This button is prohibited (grayed out) when the system is ready (mechanism is not operating).

The recount (button) is a button for restarting the count operation, and when the slide is loaded,
When this button is pressed in the stop state, the count result thus far is reset and the count is restarted. When the slide is loaded and not in the stop state,
This button is prohibited (grayed out). The next sample (button) is a button for loading the next slide. When this button is pressed while the slide is loaded and in the stop state, the counting operation of the current slide is canceled and the next sample is loaded. Starts counting operation. This button is disabled (grayed out) except when the slide is loaded and stopped.

The cassette operation selection display section 35 is a button display for operating the operation of the cassette. The next cassette (button) is a button for loading the next cassette. When this button is pressed in the stop state, Then, the counting operation of the current cassette is canceled, and the counting operation of the next cassette is started. Except in the stop state, this button is prohibited (displayed in gray) (however, if there is no next cassette, a message to that effect is displayed).

The eject button is a button for ejecting the current cassette. When this button is pressed, the current cassette counting operation is canceled, the cassette is ejected, and the system is brought into a ready state.
However, if there is another cassette at cassette position 2, when this operation is performed, that cassette is loaded into the elevator (the slide counting operation of that cassette is not automatically started). In that case, press the eject button again to eject the cassette (or use the count button to
The counting operation of the cassette is started).

Although the screen of FIG. 2 is a color screen as described above, it is black and white only, and the color cannot be identified. However, in the cassette / slide information display section 31, the screen shown in FIG. Is displayed. In the figure, Band, Seg,..., Ebl indicate the automatic classification of leukocytes. In the automatic leukocyte classification apparatus of the above-described embodiment, when any of the samples in the matrix display unit 31a is designated and input, the process proceeds as shown in the flowchart of FIG. That is, when an operation of designating a sample is performed, the determination of “whether there is an input” in step ST (hereinafter abbreviated as ST) 1 is YES, and then it is determined whether the processing status of the sample is unprocessed. (ST2). If the processing status is "unprocessed", the inspection condition for processing is displayed (ST
3) It is determined whether the condition has been changed (ST4). If there is no change, the process returns without doing anything. If there is a condition change, the changing unit is reset (ST5) and the process returns.

The processing status of the specified sample is "no slide"
If it is determined that there is no slide in ST6, YE
It is S, and it is determined that the slide is not detected (ST7).
In this case, the process returns. If the determination of ST7 as to whether or not the slide has not been detected is NO, and if the process is changed (ST8), the inspection condition is set to be processed and the process returns.

If the processing status of the specified sample is "under review" this time, the determination in ST10 becomes YES, and the screen shifts to the review screen (see FIG. 7). If the processing of the sample is "processed", the determination of whether or not the processing has been completed in ST12 is YES, and the screen shifts to the final classification screen (ST13).
If the processing status is "end of count", ST14
Is YES, the count log is displayed (ST15), and the routine returns. If the processing status is "error", the determination of "error" in ST16 is YES, and the content of the error is displayed (ST17).

The display screen of the final classification is shown in FIG. 6 (the image is red blood cells). When the review button is pressed here, a review screen is displayed as shown in FIG.

[0027]

According to the present invention, an analysis result and an image of an imaged sample are stored, and a display screen of a test progress of a predetermined sample, a sample image information display unit under test is displayed on a display screen. , And an inspection result display unit, so that even during inspection, past processing results and progress to the present can be seen at a glance.

The retest / test information can be changed by designating a sample based on the progress or test results. During the test, test information that can be changed for the sample can be set. The effect is obtained.

[Brief description of the drawings]

FIG. 1 is a block diagram showing a configuration of an automatic leukocyte classification apparatus according to an embodiment of the present invention.

FIG. 2 is a diagram showing an example of a display screen at the time of counting of the automatic white blood cell classification apparatus of the embodiment.

FIG. 3 is a diagram showing display colors corresponding to the processing status of the display screen.

FIG. 4 is a diagram showing an example of a processing status for each slide of a cassette / slide display unit on the display screen.

FIG. 5 is a flowchart for explaining processing according to the processing status in the automatic white blood cell classification apparatus of the embodiment.

FIG. 6 is a diagram showing a screen example of a final classification display of the automatic white blood cell classification apparatus of the embodiment.

FIG. 7 is a diagram showing an example of a display screen at the time of re-review of the automatic white blood cell classification apparatus of the embodiment.

[Explanation of symbols]

 31 cassette / slide information display section 31a matrix display section 31b processing status color display section 32 cell image display section 33 inspection result display section

Claims (6)

[Claims] 1. An inspection apparatus which sequentially captures an image of a sample stored in a cassette by an imaging section and automatically analyzes the sample, and displays an analysis result and an image of the sampled image in an inspection apparatus for displaying an image of the sampled image. In addition, an inspection apparatus characterized in that a display screen includes an inspection progress display unit for a sample to be processed, a sample image information display unit under inspection, and an inspection result display unit. 2. The inspection apparatus according to claim 1, wherein the inspection progress display section takes a cassette number in one of the rows and a sample number of each cassette in the other row, and displays them in a matrix. 3. The test progress progress matrix display unit according to claim 2, wherein the setting relating to the sample can be changed by designating and inputting an arbitrary point of the matrix display and designating the sample. Inspection equipment. 4. The inspection apparatus according to claim 2, wherein the inspection progress progress matrix display section displays the progress information in a color, a numerical value, a shape, a symbol, or the like according to a processing situation. . 5. The test apparatus according to claim 1, wherein the sample image information display section enables the change of the sample number and the test condition which can be changed at that time. 6. The test apparatus according to claim 1, wherein the test result display section is capable of retesting by specifying a sample in the test result.