JPH1160474A - Substrate for plaster - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject substrate exhibiting excellent application operability and applied feeling and capable of decreasing the generation of fiber scraps in case of half-cutting by laminating a resin film layer on a specific nonwoven fabric in such a manner as to get an impregnation depth of the film layer into the nonwoven fabric to be larger than a specific value. SOLUTION: The objective substrate is produced by laminating at least one surface of (A) a nonwoven fabric having an areal density of >=40 g/m<2> and a bulk density of <=0.4 g/cm<3> (e.g. spun-lace type fabric made of rayon, palyolefin or polyester) with (B) a resin film layer (e.g. a layer of polyethylene, ethylene-vinyl acetate copolymer and ethylene-methyl acrylate capolymer) in such a manner as to get the impregnation depth of the component B into the component A to be >=8 μm.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a patch support having excellent sticking properties, and more particularly, to a patch support having good half-cut properties and sticking operability.

[0002]

2. Description of the Related Art The required quality of a patch is that the intended effect (treatment, prevention, test, etc.) is first exhibited, but from the viewpoint of sticking to the skin, the ease of the sticking operation is further improved. There is a demand for adhesiveness to the skin, followability to the movement of the skin, low irritation to the skin, a feeling of sticking without discomfort, pain relief at the time of peeling, and the like.

[0003] In particular, in the case of sticking for a long time, low irritation is important as a whole. Therefore, a thin and flexible material or a thin and elastic material is used as a support. It is necessary to reduce the physical irritation to the skin by the body edge, and to provide a patch that does not show resistance to the deformation of the skin and has a little uncomfortable feeling.

However, making the support thin and flexible, or thin and elastic,
This impairs the ease of the sticking operation, which is one of the required qualities. That is, the self-supporting property is insufficient at the time of operation, so that the patch is easily deformed, and the adhesive surface is bent and sticks to each other, wrinkles are generated, and there is a problem that the patch cannot be stuck neatly.

[0005] Therefore, as one of the methods for solving the above problems, a non-woven fabric is used as a support. Since the nonwoven fabric has a porous structure, even if a nonwoven fabric having a basis weight or thickness that exhibits self-supporting properties is selected, it has flexibility and can follow the skin. However, since the nonwoven fabric is porous, when the adhesive layer and the nonwoven fabric are directly laminated when used as a patch, low-molecular-weight materials that are easily moved in the adhesive layer during the storage period migrate into the nonwoven fabric, When the pressure-sensitive adhesive layer itself sinks into the nonwoven fabric, and this tendency becomes more severe, phenomena such as the seepage of the pressure-sensitive adhesive layer on the back surface of the nonwoven fabric may occur, resulting in a decrease in performance.

In order to solve such problems, it is necessary to impregnate the nonwoven fabric with a resin, coat the surface in contact with the pressure-sensitive adhesive layer with the resin, or laminate a resin film to impart barrier properties. Is being done. For example, Japanese Patent Publication No. 61-24366 discloses an example in which a barrier layer for a drug in an adhesive is provided.

On the other hand, apart from the problem in product performance, the patch using the nonwoven fabric as a support also has a problem in production. One of the problems is that the workplace is contaminated by fiber waste generated from the nonwoven fabric. As a solution to this,
For example, a method of laminating a resin film on both sides of a nonwoven fabric can be considered. However, in this method, it is possible to prevent the generation of fiber waste in the nonwoven fabric conveying step,
When the patch is punched into a certain size, the effect of preventing the generation of fiber waste from the cross section of the cut portion is small.

In particular, for the purpose of improving the handleability as a patch, a half-cut process (cutting the support layer and the pressure-sensitive adhesive layer while leaving the protective layer) as shown in FIGS.
It has been empirically found that in the case of applying nonwoven fabric, the generation of fiber waste from the cross section of the cut portion of the nonwoven fabric increases. in this way,
Regarding measures against the support itself using nonwoven fabric,
At present it is not implemented at all.

[0009]

SUMMARY OF THE INVENTION In view of the above, it is an object of the present invention to provide a nonwoven fabric which is flexible, self-supporting, and excellent in sticking operability. An object of the present invention is to provide a patch support that can reduce the generation of waste.

[0010]

The patch support of the present invention has a basis weight of 40 g / m ² or more and a bulk density of 0.4 g.
/ Cm ³ or less, a resin film layer is laminated on at least one surface of the nonwoven fabric, and the impregnation thickness of the resin film layer into the nonwoven fabric is 8 μm or more.

Hereinafter, the present invention will be described in detail. When a nonwoven fabric is used as a support for the patch, it is flexible and easy to bend, and is not easily creased even when bent, so that it does not become difficult to apply, it is easy to apply along the skin, and the weight can be reduced compared to the apparent volume. Since it has a small bulk density, it has advantages such as being light in spite of its thickness and providing self-supporting properties that do not hang down under its own weight. Furthermore, there is also an advantage that when peeled off from the skin after application, it can be easily removed because it is easily picked.

When the thickness of the nonwoven fabric used in the present invention is reduced, the self-supporting property and the ease of picking are lost, and when the thickness is increased, the bulk density increases, so that the weight of the nonwoven fabric increases according to the thickness.
The bulk density is not more than 0.4 g / cm ³ , preferably not more than 0.3 g / cm ³ , because it hangs down and makes it difficult to stick, or the flexibility is impaired, making it difficult to stick.

Considering the relationship between thickness and bulk density,
If the bulk density is small when the thickness is small, it becomes too flexible and self-supporting is lost. Conversely, if the bulk density is large when the thickness is large, the flexibility is lost and the applicability to the skin is impaired. Therefore, the basis weight is limited to 40 g / m ² or more (the bulk density when the thickness is 80 μm is 0.2 g / cm ³ or more).

As the nonwoven fabric satisfying the above conditions, a type called spunlace is preferable, and a nonwoven fabric made of rayon, polyolefin, polyester or a mixture of these materials is used.

The bulk density is a value obtained by dividing the weight per unit area by the unit volume calculated from the measured thickness, and the thickness is 130 g / c using a dial gauge.
It is measured under a load of m ² .

The support for a patch of the present invention is obtained by laminating a resin film on at least one surface of the nonwoven fabric. This resin film is used to impart barrier properties to the nonwoven fabric and to suppress generation of fiber waste during half-cut processing. When a patch is manufactured using the above-mentioned patch support, an adhesive layer is formed on the resin film side, and a release paper is laminated on the adhesive layer.

When the patch is subjected to half-cut processing, the depth of penetration of the punching blade (die-cut roll) is restricted so as not to cut off the release paper. It is considered that a sufficient amount of uncut fibers has been generated. Therefore,
When removing unnecessary parts after half-cutting, the uncut fibers are pulled and pulled out of the non-woven fabric, and at the same time, the cut and shortened fibers around the uncut fibers are pulled out at the same time. It is considered to be.

According to the present invention, the resin film is adhered to the non-woven fabric portion where the uncut fibers are liable to be generated, for example, by heat-pressing and impregnating to bond the fibers together, and the cut and shortened fiber is pulled out of the non-woven fabric. To prevent

The larger the impregnation amount of the resin film layer, the wider the range of adhesion between fibers and the generation of fiber debris is suppressed. Therefore, the impregnation amount of the nonwoven fabric is limited to 8 μm or more as the impregnation thickness. However, if the impregnation amount is too large, the flexibility of the nonwoven fabric may be lost, and in extreme cases, pinholes may be formed in the resin film, and the barrier property may be impaired. Therefore, the impregnation thickness is preferably 2/3 or less of the total thickness of the resin film layer.

The impregnation thickness was measured by taking an electron micrograph of a cross section of the support for a patch and measuring the thickness of the coexisting region of the nonwoven fabric and the resin film layer.

The resin film laminated on at least one surface of the nonwoven fabric is preferably thin and flexible so as not to impair the flexibility of the nonwoven fabric, and the thickness of the resin film is preferably 20 to 60 μm. If the thickness of the resin film is less than 20 μm, the impregnation thickness of the nonwoven fabric becomes small, and if it exceeds 60 μm, the flexibility is lost and the flexibility of the nonwoven fabric is impaired.

When laminated on both sides of the nonwoven fabric,
The resin films on both sides need not necessarily be the same material, and may be different.

The resin film is preferably a flexible or rubber-like resin film. For example, resin films of polyethylene, ethylene-vinyl acetate copolymer and ethylene-methyl acrylate copolymer are preferably used. These may be used alone or in combination of two or more.

In addition to the above, resin films such as a styrene-isoprene-styrene copolymer, a soft vinyl chloride resin, and a polyurethane are also used. In addition, as a resin film that can be imparted with flexibility by reducing its thickness even if it is somewhat hard, for example, a resin film of polyethylene terephthalate, polypropylene, polyvinyl alcohol, or the like can be used.

When a polyethylene terephthalate film is used as the resin film, it is difficult to impregnate the nonwoven fabric, and it is preferable to laminate the film through an adhesive. When an adhesive is used, it is considered that the adhesive itself plays the role of the resin film layer.

Since polypropylene and polyvinyl alcohol films are harder than polyethylene films, they are preferably used when special performance is required. Examples of the special performance include, for example, easy adhesion to the pressure-sensitive adhesive layer and barrier properties to components of the pressure-sensitive adhesive layer.

The resin film of a polyurethane or ethylene-methyl acrylate copolymer has the advantage that it is easy to exhibit elasticity and does not impair the flexibility of the nonwoven fabric. Among them, the ethylene-methyl acrylate copolymer is inexpensive and more preferable.

Thermoplastic resins suitable for melt extrusion lamination, such as polyethylene, ethylene-vinyl acetate copolymer, ethylene-methyl acrylate copolymer, etc., can be impregnated by adjusting the lamination pressure during processing. This is preferable from the viewpoint of production because the increase and decrease can be easily adjusted.

Here, the patch is a patch containing a drug that is absorbed percutaneously and acts locally or systemically to exert a pharmacological effect for treatment and prevention; it reacts with secretions from the body and from the body surface. Including substances used for examination of diseases, odors, etc .; for the purpose of slimming, beautiful skin, protection, decoration, deodorization, fragrance, etc .; Auxiliary tools such as protection and fixation of affected parts, electrode terminals and catheters And any other sheet-like material to be stuck to the skin, and generally includes a laminate comprising a support, an adhesive layer and a protective layer.

The adhesive is obtained by applying the adhesive to the adhesive support of the present invention by a roll coater, knife coater, bar coater, die coater, spray coating or the like and drying to form an adhesive layer. be able to. Alternatively, a pressure-sensitive adhesive may be once applied to a release paper and dried to form a pressure-sensitive adhesive layer, and then the pressure-sensitive adhesive layer may be laminated on the above-mentioned patch support to obtain a patch. The release paper may be used as it is as a protective layer.

The pressure-sensitive adhesive is not particularly limited as long as it has been conventionally used for a patch.
Acrylic adhesives, rubber adhesives, and the like are preferably used.

The resin film laminated on the nonwoven fabric may be printed or embossed, or may have a multilayer structure in which a plurality of resin films are laminated.

[0033]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in more detail with reference to Examples and Comparative Examples.

(Example 1) Release-treated thickness 75 μm
Acrylic pressure-sensitive adhesive solution is applied to the release-treated surface of the polyethylene terephthalate film to a thickness of 35 μm after drying, dried to form a pressure-sensitive adhesive layer, and then laminated and laminated on a patch support. I got a body. Next, only the support and the pressure-sensitive adhesive layer of this laminate were punched out to a size of 63 mm × 63 mm using a die cut roll, and unnecessary portions around the periphery were removed.
A patch was obtained by punching into a size of 1 mm x 71 mm.
The patch support had a basis weight of 40 g / m ² and a thickness of 24 g / m ² .
0 μm rayon / polyester non-woven fabric with a thickness of 2 on one side
After laminating 0 μm of polyethylene, use a material in which polyethylene is impregnated in the non-woven fabric by heating and pressing,
An adhesive layer was laminated on the polyethylene side of the support.

(Example 2) As a support, a basis weight of 40 g /
m ^2, using what was laminated to polyethylene film of thickness 30μm on one side of rayon / polyester nonwoven fabric having a thickness of 240 .mu.m, obtained by further laminating a polyethylene film having a thickness of 30μm thereon, the total thickness 60
A patch was obtained in the same manner as in Example 1, except that an adhesive layer was laminated on the polyethylene side of μm.

(Example 3) As a support, a basis weight of 70 g /
m ² , using a laminate of an ethylene-methyl acrylate copolymer having a thickness of 45 μm on one side of a polypropylene non-woven fabric having a thickness of 300 μm, and laminating an adhesive layer on the ethylene-methyl acrylate copolymer side, A patch was obtained in the same manner as in 1.

Example 4 As a support, a basis weight of 40 g /
m ² , on one side of a polyester nonwoven fabric with a thickness of 220 μm,
After laminating a 30 μm-thick ethylene-vinyl acetate copolymer, heat-press bonding is used to impregnate the ethylene-vinyl acetate copolymer into the non-woven fabric, and the support is placed on the ethylene-vinyl acetate copolymer side of the support. A patch was obtained in the same manner as in Example 1, except that the pressure-sensitive adhesive layer was laminated.

(Example 5) As a support, a basis weight of 40 g /
m ² , on one side of a 130 μm thick polyester nonwoven fabric,
After laminating polyethylene having a thickness of 30 μm, a non-woven fabric was impregnated with polyethylene by heating and pressing, and the same procedure as in Example 1 was carried out, except that an adhesive layer was laminated on the polyethylene side of the support. A patch was obtained.

(Comparative Example 1) As a support, a basis weight of 40 g /
A patch was obtained in the same manner as in Example 1 except that a rayon / polyester nonwoven fabric having an m ² of 240 μm and a 15-μm-thick polyethylene laminated on one surface was used, and an adhesive layer was laminated on the polyethylene side. .

Comparative Example 2 As a support, a basis weight of 40 g /
After laminating a 40 μm-thick polyethylene film on one side of a rayon / polyester nonwoven fabric having a thickness of m ² and 240 μm, a polyethylene film having a thickness of 40 μm is further laminated thereon, and an adhesive layer is formed on the polyethylene side having a total thickness of 80 μm. Except for the lamination, a patch was obtained in the same manner as in Example 1.

(Comparative Example 3) As a support, a basis weight of 20 g /
m ² , using a laminate of a 20 μm thick ethylene-methyl acrylate copolymer on one side of a polyester non-woven fabric having a thickness of 70 μm and a pressure-sensitive adhesive layer laminated on the ethylene-methyl acrylate copolymer side, A patch was obtained in the same manner as in 1.

(Comparative Example 4) As a support, a basis weight of 50 g /
m ² , 120 μm-thick polyester non-woven fabric was used only on one side, and a 20 μm-thick ethylene-methyl acrylate copolymer was used, except that an adhesive layer was laminated on the ethylene-methyl acrylate copolymer side. A patch was obtained in the same manner as in Example 1.

With respect to the adhesive patches obtained in the above Examples and Comparative Examples, the performance was evaluated in the following items, and the results are shown in Table 1. (1) Ease of sticking After sticking to 10 volunteers, "easiness of sticking" was scored according to the following criteria, and the total score of the ten people was:
４０ for 40 points or more, Δ for 30 to 39 points, × for 29 points or less,
Displayed with. 5 points: Easy to apply, could be applied neatly 4 points: Difficult to apply, but could be applied cleanly 3 points: Easy to apply, but slightly wrinkled 2 points: Hard to apply, slightly wrinkled 1 point: It is difficult to paste, failed to paste

(2) Sticking comfort After sticking to 10 volunteers, the "sticking comfort" was scored according to the following criteria, and the total score of the 10 people was:
30 points or more: ○, 20 to 29 points: Δ, 19 points or less: X,
Displayed with. 4 points: did not feel discomfort in particular 3 points: felt discomfort somewhat 2 points: felt discomfort quite a bit, but could not endure 1 point: discomfort was large and could not stand

(3) The state of generation of fiber waste The state of generation of fiber waste in the support transport line of the coating and drying machine used in the patch preparation process was evaluated by visual observation.

[0046]

[Table 1]

[0047]

The support for a patch of the present invention is constituted as described above. By using a nonwoven fabric having a basis weight of 40 g / m ² or more and a bulk density of 0.4 g / cm ² or less,
Since it has self-supporting property during handling, the adhesive layers do not stick together or bend, and it does not become difficult to stick, so it has excellent sticking properties and it has flexibility during sticking, so it has a good sticking feeling give. Further, by setting the impregnated thickness of the resin film layer to 8 μm or more, it is possible to reduce the generation of fiber waste at the time of half cutting.

[Brief description of the drawings]

FIG. 1 is a schematic cross-sectional view showing an example of a patch support of the present invention.

FIG. 2 is a schematic cross-sectional view showing one example of a patch using the patch support of the present invention.

FIG. 3 (a) is a schematic cross-sectional view showing a state in which half-cut processing is performed on the patch support.
(B) is a schematic cross-sectional view showing a patch that has been subjected to half-cut processing.

FIG. 4 is a perspective view showing a state in which an unnecessary portion is peeled off after half-cut processing.

Claims (4)

[Claims] 1. A resin film layer is laminated on at least one surface of a nonwoven fabric having a basis weight of 40 g / m ² or more and a bulk density of 0.4 g / cm ³ or less, and the impregnation thickness of the resin film layer into the nonwoven fabric. Is 8 μm or more. 2. The patch support according to claim 1, wherein the material of the nonwoven fabric is at least one selected from rayon, polyester and polyolefin. 3. The resin film having a thickness of 20 to 60.
The patch support according to claim 1, wherein the support has a thickness of μm. 4. The resin film according to claim 1, wherein a material of the resin film is at least one selected from polyethylene, ethylene-vinyl acetate copolymer and ethylene-methyl acrylate copolymer. The support for a patch according to claim 1 or 2.