JPH1160423A - Antibacterial agent and antibacterial fibrous material - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an antibacterial agent and an antibacterial fibrous material utilizing thereof, capable of suppressing the generation and propagation of fungi and bacteria without polluting an environment. SOLUTION: This antibacterial agent is obtained by dispersing or dissolving 20-30 wt.% powder of Ganoderma lucidum extract extracted from the natural Ganoderma lucidum, a starch or a starch-based mixed solution obtained by mixing the starch and an enzyme (cyclodextringlucanotransferase) and as necessary a water soluble resin into water, spray drying to form a fine particles. It is possible to impart an antibacterial property not easily disappeared by a washing, etc., to a fibrous material by applying the above agent due to a surface active emulsifying activity and an adhesion after drying of the starch material, and a property of containing much oil components and a further strong adhesion after drying, of the enzyme.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an antibacterial agent capable of suppressing the occurrence and reproduction of fungi and fungi without polluting the environment, and an antibacterial fiber material using the same.

[0002]

2. Description of the Related Art Conventionally, an antibacterial agent (sterilizing agent) has been used as a fiber material for suppressing or killing mold and fungi. For example, the inorganic antibacterial agent includes Zeomic and the like, and the organic antibacterial agent includes Biosil and the like.

[0003]

However, since the above-mentioned conventional antibacterial agents are poor in water solubility, it is basically impossible to attach (fix) them to hydrophilic fiber materials such as natural fibers. Since the antibacterial agent is not sufficiently fixed even if the immersion treatment is performed for a long time, the antibacterial agent is easily washed off when the fiber material is washed with water.
Therefore, maintenance and sustainability of the antibacterial property of the fiber material was hardly achieved. Volatile or sublimable fungicides are also known, but their effect is low unless the space is sufficiently sealed. Furthermore, the antibacterial agent used is required to be non-toxic to the human body or plants and not to have an adverse effect on purified bacteria in wastewater, etc., and to have both these properties and the above-mentioned adhesion. Such antibacterial agents have been desired.

[0004]

DISCLOSURE OF THE INVENTION The present invention has been proposed in view of the above, and it has been proposed that 20 to 40% of reishi extract powder extracted from natural reishi (Ganoderma Iucidum ganoderma fruit body; hereinafter referred to as reishi) is used. An antibacterial agent characterized in that starch, or a starchy mixture of 60 to 80% of cyclodextrin glucanotransferase mixed with water is dispersed or dissolved in water and spray-dried into fine granules. It is. The antimicrobial agent may contain a water-soluble resin.

[0005] The present invention also proposes an antibacterial fiber material characterized in that the above antibacterial agent is dissolved in water, impregnated with fibers and dried.

[0006]

BEST MODE FOR CARRYING OUT THE INVENTION The ganoderma extract powder used in the present invention is obtained by washing and drying ganoderma with hot water or water, steaming it with steam, wrapping it in a fine cloth, and extracting the extract, followed by drying. This extract powder is now marketed as a health food.

[0007] The above reishi extract powder is added to starch or cyclodextrin glucanotransferase (starch degrading enzyme produced by B. Macerans,
(Hereinafter simply referred to as "enzyme") and dispersed or dissolved in water together with a starchy mixed solution. If necessary, a water-soluble resin such as methylcellulose, carboxymethylcellulose, or polyvinyl alcohol may be contained.
The above-mentioned starchy liquid mixture obtained by mixing an enzyme with starch is characterized by the fact that starch is decomposed into starchy cyclic oligosaccharides by the action of the enzyme, and specifically, α-cyclodextrin in which six glucoses are linked in a cyclic manner, Cyclically linked β-cyclodextrin, eight cyclically linked γ-cyclodextrins, 6
The mixed solution containing cyclodextrin or the like in which the number is less than or equal to the number is formed. In addition, Reishi extract powder,
The temperature at the time of dispersing or dissolving in water together with the starch or the starch mixture may be appropriately set in the range of -10 to 120 ° C. The same applies when a water-soluble resin is contained. Furthermore, Reishi extract powder is 20-40% of the total amount.
However, if it is less than 20%, the antibacterial effect is not sufficient, and if it is attempted to produce it in a proportion less than 10%, the proportion rate is difficult to measure accurately due to the production of small lots, and the quality varies. Further, even if it is more than 40%, there is no further improvement of the antibacterial effect, and not only does the component become excessive, so that not only the embossing occurs, but also the economic efficiency becomes worse. In addition, the color of the fiber material,
In particular, whiteness is impaired.

The above solution is formed into a fine granular powder by a known spray drying method.
What is necessary is just to set suitably in the range of 20-160 degreeC. In addition, when using Reishi extract powder, Reishi extract does not completely dissolve in water and a part of the extract floats on the liquid surface. By spray drying, a fine granular antibacterial agent is produced.

The antibacterial agent thus prepared is water-soluble and is a natural material, so it is harmless to the human body and plants and plants. There is no effect on

In order to fix the antibacterial agent to the fiber material, the antibacterial agent is dissolved in water at a ratio of 0.5 to 30%, and this solution is applied to the fiber material, sprayed, or Immersed in the above solution for 2 seconds to 30 minutes.
What is necessary is just to dry suitably in the range of 60 degreeC. This fiber material
It may be a fibrous fibrous material or a woven fiber product.
Also, cotton is suitable as a material.

The fiber material thus produced has an antibacterial property, and even after washing several tens of times, the antibacterial agent is hardly washed away and adheres to and remains in the fiber material, so that the antibacterial effect is maintained for a long period of time. It became something to do. Although the detailed reason is not clear, this is because the antibacterial agent is water-soluble and penetrates into the interior of the fiber. It is presumed that it firmly adheres to the surface of the fiber material due to the function and the adhesiveness after drying. In addition, it is presumed that they were denatured by heat or other factors and became insoluble in water.

In addition, when the antibacterial agent is dissolved in the dye solution in the dyeing step, the antibacterial agent can be fixed together with the dyeing in the fiber material having antibacterial properties. Moreover, it has extremely high practical value.

[0013]

Embodiments of the present invention will be described below.

Example 1 Production of antibacterial agent; Reishi extract powder (Showa Pharmaceutical Co., Ltd.) 200 g and starch 800 g, water 10,000
Dispersed and dissolved in cc, and stirred sufficiently. This solution (dispersion liquid) is spray-dried.
And dried at 90 ° C. to obtain 1000 g of an antibacterial agent.

Production of antibacterial fiber material: 25 g of the antibacterial agent obtained above was dissolved in 5000 cc of warm water for 5 minutes, and 1210 g of vegetable fiber (towel cloth) and 1210 g of rayon (fukin) were added to this solution for 5 minutes. Impregnated, 80
After drying at 30 ° C. for 30 minutes, the antibacterial agent was attached to the fiber surface.

Antibacterial effect test of antibacterial fiber material; antibacterial fiber material (towel, fukin, etc.) manufactured as described above
The Japan Chemical Fiber Inspection Association's antibacterial and deodorant processing evaluation test manual and shake flask method (test bacteria: Klebsiella pneumoniae klebsiella pneumoniaeATCC 4352, shaking conditions:
List action 330 rpm × 1 hour, test piece mass: 0.75
The sterilization rate was measured in g). The results are shown in Table 1. still,
The measurement results of the unprocessed product are also described.

[0017]

[Table 1]

Safety test of antibacterial fiber material: The cotton fabric and the towel fabric treated with the 0.1% aqueous solution of the antibacterial agent obtained above were examined for the Ministry of Health and Welfare No. 34 (Showa 49).
Year), the amount of free formaldehyde (formalin content of baby products) was tested according to the test method for baby products. The results are shown in Table 2.

[0019]

[Table 2]

Example 2 Production of antibacterial agent; Reishi extract powder (Showa Yakuhin Co., Ltd.) 200 g, starch 350 g, and cyclodextrin glucanotransferase 550 g were added to water 1
Dispersed and dissolved in 0000 cc, and sufficiently stirred. This solution (dispersion) was formed into fine granules by a spray drier (powder manufacturing machine, Saltwater Mining Sugar Co., Ltd.) and dried at 90 ° C.
25 g of the antibacterial agent were obtained.

Production of antibacterial fiber material: 25 g of the antibacterial agent obtained above was dissolved in 5000 cc of warm water for 5 minutes, and 1205 g of vegetable fiber (towel cloth) and rayon (fukin) was added to this solution for 5 minutes. Impregnated, 80
After drying at 30 ° C. for 30 minutes, the antibacterial agent was attached to the fiber surface.

Antibacterial effect test of antibacterial fiber material; antibacterial fiber material produced as described above (plain cloth, fukin, etc.)
The Japan Chemical Fiber Inspection Association's antibacterial and deodorant processing evaluation test manual and shake flask method (test bacteria: Klebsiella pneumoniae klebsiella pneumoniaeATCC 4352, shaking conditions:
List action 330 rpm × 1 hour, test piece mass: 0.75
The sterilization rate was measured in g). The results are shown in Table 3. still,
The measurement results of the unprocessed product are also described.

[0023]

[Table 3]

[Example 3] Production of antibacterial agent; Reishi extract powder (Showa Yakuhin Co., Ltd.) (200 g), starch (1000 g), and polyvinyl alcohol (20 g) were dispersed and dissolved in 10,000 cc of water and sufficiently stirred. . This solution (dispersion) was made into fine granules by a spray drier (powder manufacturing machine, Saltwater Mineral Sugar Co., Ltd.) and dried at 90 ° C. to obtain 1005 g of an antibacterial agent.

Production of antibacterial fiber material: 25 g of the antibacterial agent obtained above was dissolved in 5000 cc of warm water for 5 minutes, and 1220 g of vegetable fiber (towel cloth) and 1220 g of rayon (fukin) were added to this solution for 5 minutes. Impregnated, 80
After drying at 30 ° C. for 30 minutes, the antibacterial agent was attached to the fiber surface.

Antibacterial effect test of antibacterial fiber material; antibacterial fiber material produced as described above (plain cloth, fukin, etc.)
The Japan Chemical Fiber Inspection Association's antibacterial and deodorant processing evaluation test manual and shake flask method (test bacteria: Klebsiella pneumoniae klebsiella pneumoniaeATCC 4352, shaking conditions:
List action 330 rpm × 1 hour, test piece mass: 0.75
The sterilization rate was measured in g). The results are shown in Table 3.

[Example 4] Production of antibacterial agent; Reishi extract powder {Seiwa Pharmaceutical Co., Ltd.} 200 g, starch 1000 g, cyclodextrin glucanotransferase 10 g, and polyvinyl alcohol 10 g are dispersed in 10,000 cc of water. , Dissolved and stirred well. This solution (dispersion liquid) was made into fine granules by a spray drier (powder manufacturing machine, Shiosui Minato Sugar Co., Ltd.) and dried at 90 ° C. to obtain 1010 g of an antibacterial agent.

Production of antibacterial fiber material: 25 g of the antibacterial agent obtained above was dissolved in 5000 cc of warm water for 5 minutes, and 1210 g of vegetable fiber (towel cloth) and 1210 g of rayon (fukin) were added to this solution for 5 minutes. Impregnated, 80
After drying at 30 ° C. for 30 minutes, the antibacterial agent was attached to the fiber surface.

Antibacterial effect test of antibacterial fiber material; antibacterial fiber material produced as described above (plain cloth, fukin, etc.)
The Japan Chemical Fiber Inspection Association's antibacterial and deodorant processing evaluation test manual and shake flask method (test bacteria: Klebsiella pneumoniae klebsiella pneumoniaeATCC 4352, shaking conditions:
List action 330 rpm × 1 hour, test piece mass: 0.75
The sterilization rate was measured in g). The results are shown in Table 3.

[0030]

As described above, since the antibacterial agent of the present invention is made from Ganoderma lucidum extract powder extracted from natural Ganoderma lucidum, the antibacterial agent can inhibit the generation and reproduction of mold and fungi, or kill it. When it is disposed of in water and sewage systems, it does not affect bacteria that are purified in wastewater and does not pollute the environment.

Further, since the above-mentioned antibacterial agent is water-soluble, it has a high permeability when it is fixed to the fiber material, and the antibacterial agent reaches and adheres to the inside of the fibrin. And, due to the action of starch or starch cyclic oligosaccharide or water-soluble resin contained in the antibacterial agent, the fiber material which has been sufficiently dried can hardly be washed away even after several tens of times of washing with water, The antibacterial effect can be maintained for a long time.

Further, when producing the above-mentioned fiber material having antibacterial properties, for example, an antibacterial agent may be added to the dyeing solution and immersion treatment may be performed. In this case, a step added to the conventional processing step is substantially eliminated, so that it has extremely high practical value in industrial production.

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁶ Identification code FI D06M 13/00 D06M 13/00 // (A01N 65/00 63:00)

Claims (3)

[Claims] 1. A method in which 20 to 40% of Ganoderma lucidum extract powder extracted from natural Ganoderma lucidum and 60 to 80% of starch or a starchy mixture of cyclodextrin glucanotransferase mixed with starch are dispersed in water. An antibacterial agent characterized by being dissolved and spray-dried into fine granules. 2. Ginseng extract powder 20 to 40% extracted from natural ginseng, starch or a starchy mixture of starch mixed with cyclodextrin glucanotransferase, and a water-soluble resin in a total amount of 60 to 80. % By dispersing or dissolving in water and spray-drying to obtain fine granules. 3. An antibacterial fiber material, wherein the antibacterial agent according to claim 1 or 2 is dissolved in water, impregnated with the fiber, and dried.