JPH1157008A - Transfusion device and liquid atomizer - Google Patents

Abstract

PROBLEM TO BE SOLVED: To adjust accurately liquid delivery by providing a flexible membrane demarcating a liquid storing room and a pressure room in a pressure container, measuring internal pressure of the pressure room, introducing a fluid into the pressure room in accordance with the internal pressure and supplying the liquid from an outlet valve by pressing the liquid storing room through the flexible membrane. SOLUTION: A drug solution bag 11 is stored in a pressure container 10, and the interior of the drug solution bag 11 is connected to a micro solenoid valve 12. A check valve 14 is attached to the wall of the pressure container 10, and an air supply tube connected to a pressure pump 15 is connected thereto. A flow rate control plug 22 is connected to an injection needle 24 through an air bubble detection unit 23 by a transfusion tube 21. During operation, the internal pressure of the pressure container 10 is kept constant at all times by operating the pressure pump 15 in accordance with the internal pressure of the pressure container 10 that is detected from a pressure sensor 17 and feeding air into the pressure container 10 through the check valve 14. Drug injection is made from an injection needle 24 by opening and closing the micro solenoid valve 12 in a prescribed opening and closing cycle corresponding with transfusion speed.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an infusion device and a liquid atomizing device, and more particularly to an infusion device for delivering a medical solution to the body of a patient and a device for atomizing the solution for treatment of asthma and the like. The present invention relates to a device structure suitable for use as a liquid atomizing device for inhaling liquid into a device.

[0002]

2. Description of the Related Art Conventionally, various devices for handling liquids have been sold in the medical field in order to send medical liquids for medical use in fixed amounts and to spray the liquids as needed. Have been. In these devices,
There is a need for high certainty and safety when supplying chemicals.

[0003] As a medical infusion device, it is necessary to continue to send a medical solution accurately and safely to a patient. Therefore, in a medical solution tank section, an infusion pump, an infusion nozzle, etc., the shape accuracy, operation accuracy, durability and hygiene are not considered. High attention is needed. In the infusion device, various controlled infusion pumps are used in order to continuously send a drug solution to a human body at a predetermined speed for a long time.

For example, a chemical solution is passed through a flexible tube, and the tube is squeezed by a rotary (tube pump) or finger type actuator such as a rotor or a roller. There is an infusion pump called a peristaltic type that sends it out. Further, an infusion controller that measures the inflow speed of the chemical solution, stops the chemical solution passing through the inside of the chemical solution tube with a clamp or the like according to the inflow speed, and controls the supply speed of the chemical solution is also used. Further, there is also a syringe-type infusion device called a syringe type in which a rod inserted into a syringe is sent at a predetermined speed by a drive mechanism, and a drug solution is forcibly sent out of the syringe. In addition, there is one in which a chemical solution is extruded using a diaphragm pump.

[0005] In contrast to the infusion device provided with the above-described infusion pump, a drug solution bag containing a drug solution is deformed to push out the drug solution from the drug solution bag, or a small drug solution balloon is elastically powered by a small drug solution balloon. Infusion cartridges that extrude liquid medicines have also been put to practical use.

[0006] On the other hand, a drug nebulizer called a jet nebulizer is used for the purpose of inhaling a drug solution to a patient for treatment of asthma, emphysema, chronic bronchitis and the like.
As the chemical liquid atomizing device, a cylinder type combining a pressurized container and a spray nozzle, a spray type supplying a chemical solution put in a chemical solution tank to a spray nozzle by a pump driven by a lever, an ultrasonic wave, etc. Various types have been put to practical use, such as those atomized by high frequency vibration.

[0007]

In the above-mentioned conventional infusion device, a device provided with a syringe type, a tube type and a finger type pump has a complicated structure, so that it becomes expensive and difficult to miniaturize. There is a problem that there is. Also, those using a diaphragm pump are:
Since a negative pressure is applied to the drug solution when the drug solution is inhaled by the operation of the diaphragm, bubbles are easily generated in the drug solution, and additional mechanisms and considerations for safety are required. Furthermore, in the method using extrusion by a balloon or the like, although the structure is relatively simple, the extrusion pressure for the chemical is liable to change, and the extrusion pressure gradually decreases as time elapses from the beginning of the supply of the chemical. In addition, there is a problem that the discharge amount decreases.

On the other hand, in the nebulizer, there is a problem that the replenishing and replacement of the chemical cannot be performed in the cylinder type or the spray type, or the use posture is limited, and spraying is impossible in a tilted or upside down posture. . In addition, in a device of a type that atomizes by ultrasonic vibration or the like, the use posture is limited, such as a tabletop type, and there is a limit in miniaturization. Furthermore, although there is a large type using an air compressor, there is a problem that the use condition is limited such that the use place is limited to a room because the air compressor is stationary and the portability is poor.

Accordingly, the present invention has been made to solve the above-mentioned problems, and has as its object to stably supply a chemical solution and to make it compact and relatively inexpensive because its structure is relatively simple. It is an object of the present invention to provide an infusion device and a liquid atomizing device having characteristics such as a limited use posture.

[0010]

In order to solve the above-mentioned problems, the present invention has been made to solve the above problems by providing a closed pressurized container, a liquid storage chamber for storing a liquid in the pressurized container, and a pressurized container. A flexible membrane defining a chamber, an outlet valve attached to the liquid storage chamber, an internal pressure measuring means for measuring an internal pressure of the pressurizing chamber, and A fluid supply means for introducing a fluid.

According to this means, the liquid storage chamber in the pressurized container is pressurized through the flexible membrane by introducing a fluid into the pressurized chamber by the fluid supply means. In this pressurized state, the outlet valve is opened. It is configured to supply liquid to the outside via a liquid, so it is possible to send out the liquid stably and reliably despite its simple structure that can be reduced in size, and the liquid is not affected by the posture of the device. It is also possible to adjust the delivery amount or the delivery speed of the sheet with high precision.

Here, it is preferable that a control means for controlling the internal pressure to be substantially constant is provided.

According to this means, fluctuations in the liquid delivery pressure can be reduced by controlling the internal pressure of the pressurized vessel to be substantially constant, so that the generation of bubbles in the liquid can be suppressed and the liquid can be stabilized. And the liquid can be sent out, and the liquid sending speed can be easily controlled.

It is preferable that the apparatus further comprises control means for opening and closing the outlet valve to control a supply speed of the liquid contained in the liquid containing chamber.

According to this means, by controlling the liquid supply speed by opening and closing the outlet valve, the liquid supply speed can be reliably controlled even if the supply amount is very small.

Further, while controlling the internal pressure to be substantially constant by the internal pressure measuring means and the fluid supply means,
It is preferable that a control means for controlling the opening / closing cycle or the opening degree of the outlet valve is provided.

According to this means, the opening / closing cycle and the opening degree of the outlet valve are controlled while controlling the internal pressure of the pressurized vessel substantially constant. It can be set with high accuracy.

Next, a sealed pressurized container, a flexible film defining a liquid storage chamber and a pressurized chamber for storing a liquid in the pressurized container, Outlet valve, an internal pressure measuring means for measuring the internal pressure of the pressurizing chamber, a fluid supply means for introducing a fluid into the pressurizing chamber according to the internal pressure, and the liquid passing through the outlet valve. An atomizing unit for supplying and atomizing the liquid.

According to this means, the liquid storage chamber in the pressurized container is pressurized through the flexible membrane by introducing a fluid into the pressurized chamber by the fluid supply means, and in this pressurized state, the outlet valve is opened. It is configured to supply the liquid to the outside via the atomization unit and to atomize the liquid, so that the liquid can be sprayed stably and reliably while having a simple structure that can be miniaturized. A spray state with little change over time can be obtained without being affected by the posture.

Here, it is preferable that a gas tank for supplying a gas blown for atomizing the liquid to the atomizing section is provided.

According to this means, by spraying the gas from the gas tank to the atomizing section, the liquid can be easily atomized without being pushed out from the liquid storage bag at a high pressure. A low pressure is sufficient, the liquid can be reliably atomized, and the spray amount can be adjusted with high precision.

In this case, it is preferable that a control means for controlling the internal pressure to be substantially constant is further provided.

According to this means, the liquid can be sent out more stably by controlling the internal pressure of the pressurized container to be substantially constant, so that the spray amount of the liquid can be controlled more reliably.

[0024]

Next, an embodiment according to the present invention will be described with reference to the accompanying drawings.

(First Embodiment) FIG. 1 shows a first embodiment according to the present invention.
It is an expanded sectional view showing the structure of the operation part of the infusion device as an embodiment. The present embodiment includes a pressurized container 10 formed of a hard synthetic resin and having hermeticity,
And a liquid medicine bag 11 made of a thin flexible bag made of synthetic rubber or the like completely contained in the inside. The inside of the drug solution sac 11 is connected to a micro solenoid valve 12 which is an outlet valve fixed to the wall surface of the pressurized container 10, and also connected to a drug solution injection valve 13 similarly fixed to the wall surface of the pressurized container 10. Have been.

The liquid medicine bag 11 must be formed of a material having flexibility and liquid sealing properties, for example, a thin and flexible polymer material. As this material, a material which is rich in elasticity, follows without any change even when the volume changes greatly, and does not generate wrinkles or breakage even when the volume is reduced is desirable.

A check valve 14 is attached to the wall surface of the pressurized container 10 to allow only the flow into the pressurized container 10. Tube is attached. An air filter is attached to an intake port of the pressurizing pump 15 so as to remove dust from outside air and send the dust into the pressurizing container 10. Other parts of the wall of the pressurized container 10
The emergency release valve 16 configured to release the internal pressure when the internal pressure of the pressure vessel exceeds a normal pressure range, and the pressurized container 1
A pressure sensor 17 for detecting an internal pressure of 0 is fixed.

At the tip of the emergency release valve 16 inside the pressurized container 10, a remaining amount sensor 18 for detecting the remaining amount of the liquid medicine inside the liquid medicine sac 11 is attached. The remaining amount sensor 18 optically or acoustically detects the distance to the surface of the liquid sac 11, and sends a signal proportional to the distance to a control system described later.

The micro solenoid valve 12 is connected to an infusion tube 21, which is connected to a flow control plug 22 having an orifice therein. An air bubble detection unit 23 is attached to the tip of the flow control plug 22,
An injection needle 24 is connected to the tip of the bubble detection unit 23.

FIG. 2 is a schematic diagram showing the overall configuration of the present embodiment. Micro solenoid valve 12 and pressurizing pump 1 described above
5, the pressure sensor 17, the remaining amount sensor 18, and the bubble detection unit 23 are connected to the control unit 27 via the input / output circuit 26.
It is connected to the. An alarm output unit 28, a display unit 29, and a setting operation unit 30 are connected to the control unit 27. The control unit 27 may be a circuit including a wired logic circuit designed in advance,
It may be constituted by a microprocessor unit (MPU) including an arithmetic processing unit (CPU), ROM, RAM and the like.

The control unit 27 is configured to control the above-described operation parts according to a preset program and the setting contents and operation contents of the setting operation unit 30. Normally, during operation, the control unit 27 operates the pressurizing pump 15 in accordance with the internal pressure of the pressurized container 10 detected by the pressure sensor 17, and supplies air into the pressurized container 10 via the check valve 14. , The pressurized container 10
Is always kept constant. For example, when this infusion device is used for the human body, a pressure slightly higher than the internal pressure of about 1.2 atm (when the natural environment is 1 atm) (about 1.3 to 1.5 atm: natural environment (When the pressure is 1 atm), the internal pressure of the pressurized container 10 is maintained.

When a start operation is performed on the setting operation unit 30, the control unit 27 opens and closes the micro solenoid valve 12 in a predetermined opening / closing cycle according to a preset infusion rate in the setting operation unit 30. Micro solenoid valve 12
Has, for example, a predetermined opening and closing cycle,
By increasing the ratio (duty ratio) of the time during which the valve is open in this opening / closing cycle in proportion to the set value of the infusion speed, it is possible to obtain an almost infusion speed as set.

The control of the supply amount of the chemical solution by the outlet valve can be performed by controlling the opening degree of the outlet valve instead of controlling the opening / closing timing of the micro solenoid valve as described above.

When the supply of the drug solution from the micro solenoid valve 12 is started, the volume of the drug solution sac 11 gradually decreases, and the internal pressure of the pressurized container 10 decreases. Control unit 27
When the pressure sensor 17 detects that the internal pressure has decreased, the pressure pump 17 is operated to feed air into the interior of the pressure vessel 10, and when the internal pressure is restored, the pressure pump 15 is stopped. By this repetition, the supply of the chemical is continued while the internal pressure of the pressurized container 10 is always maintained at the predetermined pressure value. The control unit 27 displays the supply speed of the chemical on the display unit 29 during the supply of the chemical.

When the liquid medicine is supplied through the micro solenoid valve 12 and the liquid medicine sac 11 is gradually reduced, the distance measured by the remaining amount sensor 18 is gradually increased, and the control unit 27 uses this distance to perform a predetermined conversion. The remaining amount of the liquid medicine in the liquid medicine sac 11 is calculated based on the table and displayed on the display unit 29. Since the distance detected by the remaining amount sensor 18 and the remaining amount of the liquid medicine are usually not completely inversely proportional, the relationship between the distance and the remaining amount is calculated in advance in consideration of the shape change of the liquid medicine sac 11, or Experimentally determine the relationship between distance and remaining amount
The result is incorporated in the control unit 27 in the form of a conversion table or a conversion formula.

Note that instead of providing the remaining amount sensor 18,
The air volume supplied into the pressurized container 10 by the pressurized pump 15 is roughly integrated in the control unit 27,
It is also possible to obtain the remaining amount of the drug solution by subtracting this integrated amount from the volume of the drug solution initially filled in the drug solution sac 11.

If the temperature of the device rises during operation or the like due to outside air temperature, body temperature or some other cause, the internal pressure of the pressurized container 10 may become abnormally high and hinder infusion control. For this reason, an emergency release valve 16 for releasing the internal pressure of the pressurized container 10 before the internal pressure does not reach the dangerous pressure is provided. Even if it is not such an abnormal situation, it is also possible to release the internal pressure in order to control the internal pressure of the pressurized container 10.

A known bubble detector such as an optical type or an ultrasonic vibration type is incorporated in the bubble detecting unit 23. When bubbles are present in the chemical solution sent from the chemical tube 21 to the injection needle 24, the control unit 27 is activated. Report that effect. The control unit 27 issues an alarm from the alarm output unit 28 and executes processing such as stopping the infusion.

When the amount of the drug solution in the drug solution sac 11 decreases, the tube connected to the drug solution supply device can be connected to the drug solution injection valve 13 to replenish the drug solution. In this case, the pressurized container 10 may be configured to be openable, so that the liquid capsule 11 itself can be replaced.

In the present embodiment, the liquid medicine is continuously supplied by extruding the liquid medicine from the liquid medicine sac, similarly to the conventional liquid medicine bag or balloon type, so that the structure is relatively simple and the size is small. It is also possible to make the configuration, and at the same time, it can be constructed at a low cost.

Further, in this embodiment, since the liquid medicine bag 11 is completely contained in the inside of the pressurized container 10 and the pressure applied by the pressurized container 10 is controlled, the instability of the liquid medicine supply is avoided. And highly accurate, stable and reliable infusion can be performed with high reliability.

Also, since the liquid medicine bag 11 is pressurized in the closed pressurized container 10, there is little energy loss, and it can be driven with small power and energy consumption.

Further, since the chemical is always supplied in the most suitable pressurized state without pressure fluctuation, the generation of bubbles is small,
It is safe.

In the present embodiment, the supply and cutoff of the chemical solution can be reliably controlled by the micro solenoid valve 12 serving as the outlet valve, and the pushing force of the chemical solution can be set only by the internal pressure of the pressurized container 10. Therefore, the operation depends on the posture of the device. It does not change and can be used without being restricted by the posture.

Second Embodiment Next, a second embodiment according to the present invention will be described.
A jet nebulizer as an embodiment will be described with reference to FIG. In this embodiment, the first
It is provided with a pressurized container 10, a liquid medicine bag 11, a micro solenoid valve 12, a liquid medicine injection valve 13, a check valve 14, a pressure pump 15, an emergency discharge valve 16, a pressure sensor 17, and a remaining amount sensor 18 which are completely the same as those of the embodiment. I have. Although not shown, a control unit connected to the micro solenoid valve 12, the pressure pump 15, the pressure sensor 17, and the remaining amount sensor 18 is provided, and the control unit maintains the internal pressure of the pressure vessel 10 at a predetermined pressure. It is configured to be able to.

In this embodiment, a chemical solution tube 31 is connected to the micro solenoid valve 12, and a spray nozzle 32 is connected to the tip of the chemical solution tube 31.

In this embodiment, when an operation button (not shown) is pressed in a state where the inside of the pressurized container 10 is maintained at a predetermined internal pressure, the micro solenoid valve 12 is opened for a predetermined time, and the liquid capsule 11 is opened by the internal pressure of the pressurized container 10. The chemical is extruded from the mist, is atomized by the spray nozzle 32, and is blown out in the form of mist. Such an operation is the same as that of a normal spray-type or cylinder-type nebulizer.
Since the internal pressure of 0 can be controlled at all times, the internal pressure does not need to be extremely high as in the cylinder type, which is safe, and the pressure change over time can be eliminated. On the other hand, in the case of the spray type, the operation force of the lever for sucking up the chemical solution is not required, and the elderly person without muscle strength can easily use it.

In this embodiment, the size and size can be relatively reduced, and the reliability and stability are excellent while being inexpensive.
In addition, the spraying of the chemical liquid does not become impossible depending on the posture as in the spray type and the cylinder type, so that the chemical liquid can be surely sprayed in any posture.

(Third Embodiment) Next, the structure of a third embodiment according to the present invention will be described with reference to FIG. This embodiment is configured as a nebulizer similarly to the second embodiment. In this embodiment, as shown in FIG. 4, an accumulator 33 as a gas tank for storing compressed air in advance is prepared separately from the pressurized container 10, and the accumulator 33 is provided with a micrometer for discharging compressed air. A micro solenoid valve 34 with a regulator is connected. In addition to the accumulator 33, a check valve 35 with an opening / closing mechanism connected to the pressurizing pump 15 via an air supply tube, and a pressure sensor 36 for detecting the internal pressure of the accumulator 33 are attached.

In this embodiment, the same components as those in the first and second embodiments are denoted by the same reference numerals, and the description thereof will be omitted. However, the check valve 14 connected to the pressurized container 10
Is provided with an opening / closing mechanism similarly to the check valve 35.

A liquid supply pipe 37 extending straight is connected to the micro solenoid valve 12 connected to the pressurized container 10, and the micro solenoid valve 34 of the accumulator 33 is bent in the middle to supply the liquid supply pipe 37. An air supply pipe 38 having an open end is connected near the tip of 37. The open end of the air supply pipe 38 is arranged so that air can be blown against the tip of the liquid supply pipe 37.

In this embodiment, the pressurized container 10 is constantly controlled to a predetermined internal pressure as in the previous embodiments, and by opening the micro solenoid valve 12, the drug solution contained in the drug solution sac 11 is opened. Can be discharged from the liquid supply pipe 37 to the outside. Here, the check valve 14
When the internal pressure of the pressurized container 10 reaches a predetermined internal pressure, if the pressurized pump cannot be stopped, in order to prevent air from flowing in from the pressurized pump 15 further, it is forcibly based on a command from the control unit 27. It is configured to be closed.

On the other hand, in the accumulator 33, the compressed air supplied from the pressurizing pump 15 is always stored.
Usually, about 2 to 5 atm higher than the internal pressure of the pressurized container 10,
Preferably, the internal pressure is maintained at about 2 to 3 atm. The internal pressure of the accumulator 33 is maintained by introducing air supplied by the pressurizing pump 15 through a check valve 35, detecting the internal pressure by a pressure sensor 36, and, when the internal pressure reaches a predetermined pressure, by the control unit 27. Is stopped, or the check valve 35 is forcibly closed by a control signal from the control unit 27.

The air supply to the pressurized container 10 and the accumulator 33 is automatically performed at an appropriate time according to the respective needs. Since the pressurizing pump 15 sends compressed air to both the pressurizing container 10 and the accumulator 33, the control unit 27 forces the check valve 35 when only the pressurizing container 10 is supplied with air. Close and accumulator 33
When air is supplied only to the check valve 14, the check valve 14 is forcibly closed.

When a predetermined operation is performed in the setting operation section 30, the micro solenoid valve 12 is opened for a predetermined time and a predetermined amount of the chemical flows into the liquid supply pipe 37. Next, the micro solenoid valve 34 is opened for a predetermined time, and the compressed air is pushed out from the accumulator 33 to the air supply pipe 38. At this time, the micro-regulator provided along with the micro-electromagnetic valve 34 adjusts the pressure of the air discharged from the accumulator 33 to the air supply pipe 38 to a predetermined pressure based on a control signal from the control unit 27. The air blown out from the air supply pipe 38 is blown against the chemical solution coming out from the tip of the liquid supply pipe 37,
Atomize chemical solution. The air blown from the air supply pipe 38 atomizes the chemical at the tip of the liquid supply pipe 37 and simultaneously sucks up the chemical at the back of the liquid supply pipe 37, so that all the chemicals in the liquid supply pipe 37 are completely atomized. Be transformed into

In this embodiment, since the chemical solution can be forcibly atomized by high air pressure by providing the accumulator 33, the atomization efficiency can be increased and the amount of atomization can be increased. Relatively easy. In addition, since the pressure of atomization and blowing can be applied from the accumulator 33, the pressure vessel 1
On the 0 side, it is possible to extrude the chemical at a low pressure, so that the discharge amount of the chemical can be set with high accuracy.

In this embodiment, the compressed air can be stored in the accumulator 33 in advance, so that the pressure pump can be downsized.

(Fourth Embodiment) Next, referring to FIG.
A fourth embodiment showing an example of a specific device configuration that can be applied to the infusion device or the liquid atomizing device of the first to third embodiments will be described. In this embodiment, a pressurized container 10 containing a liquid medicine bag 11 is made detachable in a cassette type. Hereinafter, a structure based on the infusion device of the first embodiment will be described.

As described above, the liquid container 11 is housed in the pressurized container 10, and the micro solenoid valve 12, the liquid inlet 13, the check valve 14, the emergency release valve 16, the pressure sensor 17, and the remaining The quantity sensor 18 is fixed. Here, the micro solenoid valve 12, the pressure sensor 17, and the remaining amount sensor 18
Has one or more electrodes for transmitting signals on its respective outer surfaces.

On the other hand, the apparatus 40 is provided with a housing chamber 40a for receiving the pressurized container 10, and the inside thereof is in contact with a joint portion connectable to the micro solenoid valve 12 and the above-mentioned electrode of the micro solenoid valve 12. An electromagnetic valve connecting portion 41 having a counter electrode, a joint portion 42 connectable to the check valve 14, a counter electrode 43 for contacting the electrodes provided on the pressure sensor 17 and the remaining amount sensor 18, respectively;
44 are arranged.

When the liquid medicine inside the liquid capsule 11 is exhausted as described above, the pressurized container 10 is removed from the accommodation chamber 40a, and the pressurized liquid after refilling the liquid container 11 with a new pressurized container 10 or liquid liquid bag 11 is removed. The container 10 is mounted inside the accommodation chamber 40a as shown by the arrow in the figure. When the pressurized container 10 is completely mounted, the micro solenoid valve 12 is connected to the solenoid valve connection part 41, and the outlet side of the micro solenoid valve 12 is connected to the chemical tube 2.
Communicated with 1. Similarly, the check valve 14 is
2 and connected to a pressure pump (not shown) in the device 40. Furthermore, the micro solenoid valve 1 of the pressurized container 10
2. The electrodes provided on the pressure sensor 17 and the remaining amount sensor 18 come into contact with the counter electrode provided on the solenoid valve connecting portion 41 and the counter electrodes 43 and 44,
The pressure sensor 17 and the remaining amount sensor 18 are electrically connected to a control unit (not shown).

In the present embodiment, the pressurized container 10 is
In this case, the cartridge type is detachably configured, so that the replenishment or replacement of the chemical solution is facilitated, and the workability can be greatly improved.

In each of the above embodiments, air is introduced into the pressurized container. However, what is introduced may be a gas other than air, for example, an inert gas or a fluid other than gas. You may. For example, it is possible to indirectly adjust the internal pressure by gradually putting a liquid or a powdery substance into a pressurized container into which gas has been introduced, and to make the entire surface of the liquid storage bag uniform. Although it is not possible to pressurize the liquid container, it is possible to pressurize the liquid storage bag and operate in substantially the same manner as in the above-described embodiment even when only the liquid or powdery substance is put into the pressurized container.

In each of the above-described embodiments, the liquid container such as a liquid medicine bag is completely contained in the pressurized container, and the liquid container is pressurized by introducing a fluid into the pressurized container. However, a structure in which a flexible film is attached in the form of a partition inside the pressurized container and the liquid storage chamber and the pressurized chamber are partitioned may be adopted. Both of these have a structure in which a liquid storage chamber and a pressurized chamber are defined by a flexible film inside a pressurized container, and the present invention makes it possible for the first time to stably deliver a liquid by such a structure. This is a very remarkable effect that has not been achieved in the past.

[0065]

As described above, according to the present invention, the following effects can be obtained.

According to the first aspect, the liquid storage chamber in the pressurized container is pressurized through the flexible membrane by introducing a fluid into the pressurized chamber by the fluid supply means. It is configured to supply the liquid to the outside via the, so it is possible to send out the liquid stably and reliably despite the simple structure that can be miniaturized, without being affected by the posture of the device, The amount or speed at which the liquid is delivered can also be adjusted with high precision.

According to the second aspect, by controlling the internal pressure of the pressurized container to be substantially constant, it is possible to reduce the fluctuation of the liquid delivery pressure, thereby suppressing the generation of bubbles in the liquid and the like. The liquid can be sent out stably, and the control of the liquid sending speed can be easily performed.

According to the third aspect, by controlling the supply speed of the liquid by opening and closing the outlet valve, the supply speed of the liquid can be reliably controlled even if the supply amount is very small.

According to the fourth aspect, while controlling the opening / closing cycle and opening degree of the outlet valve while controlling the internal pressure of the pressurized vessel substantially constant, the supply amount and the supply speed of the liquid are controlled. Can be set with high precision.

According to the fifth aspect, the liquid storage chamber in the pressurized container is pressurized through the flexible membrane by introducing a fluid into the pressurized chamber by the fluid supply means. It is configured to supply the liquid to the outside via the atomization unit and atomize in the atomization unit, so that the liquid can be sprayed stably and reliably while having a simple structure that can be miniaturized, A spray state with little change over time can be obtained without being affected by the attitude of the apparatus.

According to the sixth aspect, by spraying the gas from the gas tank to the atomizing section, the liquid can be easily atomized without being pushed out from the liquid storage bag at a high pressure. The internal pressure is low enough, and the atomization of the liquid can be reliably performed, and the spray amount can be adjusted with high precision.

According to the seventh aspect, since the internal pressure of the pressurized container is controlled to be substantially constant, the liquid can be sent out more stably, so that the spray amount of the liquid can be controlled more reliably.

[Brief description of the drawings]

FIG. 1 is an enlarged sectional view of a main part showing a structure of a first embodiment according to the present invention.

FIG. 2 is a schematic configuration diagram illustrating an overall configuration of the first embodiment.

FIG. 3 is an enlarged sectional view of a main part showing a structure of a second embodiment according to the present invention.

FIG. 4 is a schematic configuration diagram showing an overall configuration of a third embodiment according to the present invention.

FIG. 5 is a schematic partial sectional view showing a fourth embodiment according to the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 10 Pressurized container 11 Chemical sac 12,34 Micro solenoid valve 14,35 Check valve 15 Pressure pump 16 Emergency release valve 17,36 Pressure sensor 18 Remaining amount sensor 21,31 Infusion tube 22 Flow control plug 23 Bubble detection unit 24 Injection needle 26 Input / output circuit 27 Control unit 28 Alarm output unit 29 Display unit 30 Setting operation unit 32 Spray nozzle 33 Accumulator 37 Liquid supply pipe 38 Air supply pipe 40 Device 40a Storage chamber 42 Joint unit 43, 44 Counter electrode

Claims (7)

[Claims] 1. A sealed pressure vessel, a flexible film defining a liquid chamber and a pressure chamber for accommodating a liquid in the pressure vessel, and a flexible film attached to the liquid chamber. An infusion device, comprising: an outlet valve, an internal pressure measuring means for measuring an internal pressure of the pressurizing chamber, and a fluid supply means for introducing a fluid into the pressurizing chamber according to the internal pressure. . 2. The infusion device according to claim 1, further comprising control means for controlling the internal pressure to be substantially constant. 3. The infusion device according to claim 1, further comprising control means for opening and closing the outlet valve to control a supply speed of the liquid stored in the liquid storage chamber. 4. The control device according to claim 1, further comprising control means for controlling the opening / closing cycle or opening degree of the outlet valve while controlling the internal pressure to be substantially constant by the internal pressure measuring means and the fluid supply means. An infusion device characterized by the above-mentioned. 5. A closed pressurized container, a flexible film defining a liquid storage chamber and a pressurized chamber for storing a liquid in the pressurized container, and attached to the liquid storage chamber. An outlet valve, an internal pressure measuring means for measuring an internal pressure of the pressurizing chamber, a fluid supply means for introducing a fluid into the pressurizing chamber according to the internal pressure, and the liquid supplied through the outlet valve. And an atomizing section for atomizing the liquid. 6. The liquid atomizing apparatus according to claim 5, further comprising a gas tank for supplying a gas blown to atomize the liquid to the atomizing section. 7. The infusion device according to claim 5, further comprising control means for controlling the internal pressure to be substantially constant.