JPH1147261A - Medical instrument - Google Patents
Medical instrumentInfo
- Publication number
- JPH1147261A JPH1147261A JP9208739A JP20873997A JPH1147261A JP H1147261 A JPH1147261 A JP H1147261A JP 9208739 A JP9208739 A JP 9208739A JP 20873997 A JP20873997 A JP 20873997A JP H1147261 A JPH1147261 A JP H1147261A
- Authority
- JP
- Japan
- Prior art keywords
- vinyl chloride
- chloride resin
- resin composition
- phosphite
- antibacterial agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、銀イオン担持無機
系抗菌剤を含有する塩化ビニル樹脂組成物からなる医療
用具に関し、詳しくは、経時的な変色の改善された前記
医療用具に関する。The present invention relates to a medical device comprising a vinyl chloride resin composition containing a silver ion-carrying inorganic antibacterial agent, and more particularly, to a medical device improved in discoloration over time.
【０００２】[0002]
【従来の技術】従来より無機系抗菌剤を各種の樹脂に混
練もしくはコーティングし、抗菌性の成形物を得ること
が行われている。しかしながら、樹脂として塩化ビニル
樹脂を用い、無機系抗菌剤として抗菌効果の高い銀イオ
ン担持無機系抗菌剤を用いた場合には、成形物が経時的
に茶褐色に変色する傾向が見られ、問題であった。そこ
で、このような変色を改善するために、ゼオライト担体
中に含有させる銀イオン等の抗菌性金属イオンをアンモ
ニア錯体やアミン錯体として導入し、ゼオライト担体表
面に過剰な抗菌性金属イオンが存在しないようにしたも
のや（特公平５−６７６６７号公報）、ゼオライト担体
中に銀イオンと共にアンモニウムイオンを担持させたも
の（特公平４−２８６４６号公報）などが提案されてい
る。しかしながら、これらの無機系抗菌剤を塩化ビニル
樹脂組成物に含有させた場合には、成形品の顕著な経時
的変色の改善が困難であり、成形品の商品価値を著しく
損なうものであった。2. Description of the Related Art Conventionally, an inorganic antibacterial agent has been kneaded or coated with various resins to obtain an antibacterial molded product. However, when a vinyl chloride resin is used as the resin and a silver ion-carrying inorganic antibacterial agent having a high antibacterial effect is used as the inorganic antibacterial agent, the molded article tends to turn brown over time, which is a problem. there were. Therefore, in order to improve such discoloration, an antibacterial metal ion such as silver ion to be contained in the zeolite carrier is introduced as an ammonia complex or an amine complex so that there is no excess antibacterial metal ion on the zeolite carrier surface. And Japanese Patent Publication No. 5-28667, and a zeolite carrier in which ammonium ions are supported together with silver ions in a zeolite carrier (Japanese Patent Publication No. 4-28646). However, when these inorganic antibacterial agents are contained in the vinyl chloride resin composition, it is difficult to improve the remarkable discoloration of the molded article with time, which significantly impairs the commercial value of the molded article.
【０００３】[0003]
【発明が解決しようとする課題】本発明は、如上の事情
に鑑みてなされたもので、銀イオン担持無機系抗菌剤を
含有する塩化ビニル樹脂組成物からなる医療用具におい
て、抗菌効果を損なうことなく経時的変色を改善するこ
とを目的とする。SUMMARY OF THE INVENTION The present invention has been made in view of the above circumstances, and is intended to impair the antibacterial effect of a medical device comprising a vinyl chloride resin composition containing a silver ion-carrying inorganic antibacterial agent. Without discoloration over time.
【０００４】[0004]
【課題を解決するための手段】銀イオン担持無機系抗菌
剤を含有する塩化ビニル樹脂組成物の変色は、光、温
度、水分などにより加速される。本発明者等は、鋭意検
討の結果、塩化ビニル樹脂に一般的に配合される添加
剤、特に亜リン酸エステル系添加剤を添加しない場合、
経時的な変色が顕著に改善されることを見出し、本発明
に到達した。すなわち、本発明は、無機担体に銀イオン
を担持させてなる抗菌剤を含有し、かつ亜リン酸エステ
ルを含有しない、塩化ビニル樹脂組成物からなる医療用
具である。ここで、塩化ビニル樹脂は、５０重量％以上
の塩化ビニル構造単位を有するものが好ましく、無機担
体は、ゼオライト、アルミノケイ酸、リン酸ジルコニウ
ム、多孔質ガラス、多孔質シリカ、アルミナ、ポリリン
酸アルミニウム、ヒドロキシアパタイト、チタニア、シ
リカゲルの群から選ばれる少なくとも１つが好ましい。
以下、本発明を詳しく説明する。The discoloration of a vinyl chloride resin composition containing a silver ion-carrying inorganic antibacterial agent is accelerated by light, temperature, moisture and the like. The present inventors, as a result of intensive studies, additives not generally added to the vinyl chloride resin, especially when not adding a phosphite-based additive,
The present inventors have found that discoloration over time is remarkably improved, and have reached the present invention. That is, the present invention is a medical device comprising a vinyl chloride resin composition containing an antibacterial agent having silver ions carried on an inorganic carrier and containing no phosphite. Here, the vinyl chloride resin preferably has a vinyl chloride structural unit of 50% by weight or more, and the inorganic carrier includes zeolite, aluminosilicate, zirconium phosphate, porous glass, porous silica, alumina, aluminum polyphosphate, At least one selected from the group consisting of hydroxyapatite, titania and silica gel is preferred.
Hereinafter, the present invention will be described in detail.
【０００５】塩化ビニル樹脂に配合される添加剤として
は、可塑剤、エポキシ化合物、金属石鹸、亜リン酸エス
テル化合物、フェノール系酸化防止剤、着色剤、充填剤
等が挙げられる。可塑剤としては、フタル酸エステル
類、ジアルキルチオジプロピオン酸エステル類、リン酸
エステル類が挙げられ、これらの中、ジアルキルチオジ
プロピオン酸エステル類、リン酸エステル類が軽度の変
色原因物質である。また、フェノール系酸化防止剤も軽
度の変色原因物質であり、特に強い変色原因物質は亜リ
ン酸エステル化合物である。このような変色原因となる
亜リン酸エステル化合物としては、トリオクチルホスフ
ァイト、トリイソオクチルホスファイト、トリノニルホ
スファイト、トリラウリルホスファイト、トリオクタデ
シルホスファイト、ジオクチルアシットホスファイト、
トリラウリルトリチオホスファイト、ジステアリルペン
タエリスリトールジホスファイト等のアルキルホスファ
イト類、トリフェニルホスファイト、トリクレジルホス
ファイト、トリノニルフェニルホスファイト、ジフェニ
ルデシルホスファイト、４．４, −ブチリデン−ビス
（３−メチル−６−ｔ−ブチルフェニル）ジトリデシル
ホスファイト等のアリールホスファイト類およびアルキ
ルアリールホスファイト類の１種または２種以上の混合
物を挙げることができる。[0005] Examples of additives to be added to the vinyl chloride resin include a plasticizer, an epoxy compound, a metal soap, a phosphite compound, a phenolic antioxidant, a coloring agent, a filler and the like. Examples of the plasticizer include phthalates, dialkylthiodipropionates, and phosphates, and among these, dialkylthiodipropionates and phosphates are substances causing slight discoloration. . Phenolic antioxidants are also mild discoloration causing substances, and particularly strong discoloration causing substances are phosphite compounds. Examples of the phosphite compound causing such discoloration include trioctyl phosphite, triisooctyl phosphite, trinonyl phosphite, trilauryl phosphite, trioctadecyl phosphite, dioctyl acid phosphite,
Alkyl phosphites such as trilauryl trithio phosphite, distearyl pentaerythritol diphosphite, triphenyl phosphite, tricresyl phosphite, trinonyl phenyl phosphite, diphenyl decyl phosphite, 4.4 , -butylidene-bis One or a mixture of two or more of aryl phosphites such as (3-methyl-6-t-butylphenyl) ditridecyl phosphite and alkylaryl phosphites can be mentioned.
【０００６】本発明における塩化ビニル樹脂としては、
ポリ塩化ビニルあるいはエチレン−塩化ビニル共重合
体、プロピレン−塩化ビニル共重合体、塩化ビニル−酢
酸ビニル共重合体、ステアリン酸ビニル−塩化ビニル共
重合体、ラウリルビニルエーテル−塩化ビニル共重合体
等の共重合体、およびエチレンビニルアルコール共重合
体とポリ塩化ビニルのグラフト重合体、ポリ塩化ビニル
と塩素化ポリエチレン、メチルメタクリレート−ブタジ
エン−スチレン共重合体等とのポリマーブレンド等であ
って、塩化ビニル構造単位を５０重量％以上有するもの
を挙げることができる。In the present invention, the vinyl chloride resin includes
Polyvinyl chloride or copolymers of ethylene-vinyl chloride copolymer, propylene-vinyl chloride copolymer, vinyl chloride-vinyl acetate copolymer, vinyl stearate-vinyl chloride copolymer, lauryl vinyl ether-vinyl chloride copolymer, etc. A polymer blend of a polymer, an ethylene-vinyl alcohol copolymer and a polyvinyl chloride, a polyvinyl chloride and a chlorinated polyethylene, a methyl methacrylate-butadiene-styrene copolymer, etc. Having 50% by weight or more.
【０００７】本発明における銀イオンの無機担体として
は、ゼオライト、アルミノケイ酸、リン酸ジルコニウ
ム、多孔質ガラス、多孔質シリカ、アルミナ、ポリリン
酸アルミニウム、ヒドロキシアパタイト、チタニア、シ
リカゲル等を挙げることができる。これらの担体は、２
種以上の複合体にすることもでき、その粒径は５ミクロ
ン以下、好ましくは１ミクロン以下である。The inorganic carrier for silver ions in the present invention includes zeolite, aluminosilicate, zirconium phosphate, porous glass, porous silica, alumina, aluminum polyphosphate, hydroxyapatite, titania, silica gel and the like. These carriers are 2
Composites of more than one species can also be formed, the particle size of which is less than 5 microns, preferably less than 1 micron.
【０００８】[0008]
【発明の実施の形態】本発明の医療用具は、塩化ビニル
樹脂に銀イオン担持無機系抗菌剤、可塑剤、エポキシ化
合物、金属石鹸および必要により着色剤を配合した、亜
リン酸エステルを含まない組成物を成形してなるもので
あり、各種カテーテルやチューブ、輸液バッグ、血液バ
ッグ等の形成に採用される。以下に実施例を示すが、本
発明はこれによって限定されるものではない。BEST MODE FOR CARRYING OUT THE INVENTION The medical device of the present invention does not contain a phosphite in which a vinyl chloride resin is mixed with an inorganic antibacterial agent carrying silver ions, a plasticizer, an epoxy compound, a metal soap and, if necessary, a coloring agent. It is formed by molding a composition and is used for forming various catheters, tubes, infusion bags, blood bags and the like. Examples will be shown below, but the present invention is not limited thereto.
【０００９】〔実施例１〕ポリ塩化ビニルにフタル酸ジ
オクチル（ＤＯＰ）、エポキシ化大豆油（ＥＯＰ）、Ca
-Zn ステアレート、銀イオン担持無機抗菌剤（ゼオミッ
ク：（株）シナネン製）を配合した表１に示すような塩
化ビニル樹脂組成物を混練してペレットを得、このペレ
ットをポリテトラフルオロエチレン製のシートの間で１
５０℃、１００ｋｇ／ｃｍ2 でポットプレスして厚さ
１．５ｍｍのシートに成形した。このシートを６０℃、
相対湿度７５％の雰囲気で１０日間および４０日間放置
後、白色濾紙を裏面に当て、日本電色社製Ｅ５１００型
色差計で色を測定したところ、表２に示すような結果が
得られた。結果はＣＩＦ１９７６によるＬ* ａ* ｂ* 表
色系（ｂ* は省略）で表している。[Example 1] Dioctyl phthalate (DOP), epoxidized soybean oil (EOP), Ca
-Zn stearate, a vinyl chloride resin composition as shown in Table 1 blended with silver ion-carrying inorganic antibacterial agent (Zeomic: manufactured by Sinanen Co., Ltd.) was kneaded to obtain pellets, and the pellets were formed of polytetrafluoroethylene. One among the sheets of
It was formed into a 1.5 mm thick sheet by pot pressing at 50 ° C. and 100 kg / cm 2 . 60 ° C
After standing for 10 days and 40 days in an atmosphere at a relative humidity of 75%, the white filter paper was applied to the back surface, and the color was measured using a color difference meter E5100 manufactured by Nippon Denshoku Co., Ltd. The results shown in Table 2 were obtained. The results are expressed in the L * a * b * color system (b * is omitted) according to CIF1976.
【００１０】〔実施例２〕実施例１においてゼオミック
の配合量を少なくした表１に示すような塩化ビニル樹脂
組成物を混練してペレットを得、このペレットから実施
例１と同様のシートを成形し、実施例１と同様の色測定
を行ったところ、表２に示すような結果が得られた。Example 2 A vinyl chloride resin composition as shown in Table 1 in which the amount of Zeomic was reduced in Example 1 was kneaded to obtain pellets, and a sheet similar to that of Example 1 was formed from the pellets. Then, when the same color measurement as in Example 1 was performed, the results shown in Table 2 were obtained.
【００１１】〔比較例１〕ポリ塩化ビニルにＤＯＰ、Ｅ
ＯＰ、Ca-Zn ステアレート、ゼオミック、ＴＮＰＰを配
合した表１に示すような塩化ビニル樹脂組成物を混練し
てペレットを得、このペレットから実施例１と同様のシ
ートを成形し、実施例１と同様の色測定を行ったとこ
ろ、表２に示すような結果が得られた。Comparative Example 1 DOP and E were added to polyvinyl chloride.
A vinyl chloride resin composition as shown in Table 1 containing OP, Ca-Zn stearate, zeomic and TNPP was kneaded to obtain pellets, and a sheet similar to that of Example 1 was formed from the pellets. When the same color measurement was performed, the results shown in Table 2 were obtained.
【００１２】〔比較例２〕ポリ塩化ビニルにＤＯＰ、Ｅ
ＯＰ、Ca-Zn ステアレートを配合した表１に示すような
塩化ビニル樹脂組成物を混練してペレットを得、このペ
レットから実施例１と同様のシートを成形し、実施例１
と同様の色測定を行ったところ、表２に示すような結果
が得られた。Comparative Example 2 DOP and E were added to polyvinyl chloride.
A vinyl chloride resin composition as shown in Table 1 containing OP and Ca-Zn stearate was kneaded to obtain pellets, and a sheet similar to that of Example 1 was formed from the pellets.
When the same color measurement was performed, the results shown in Table 2 were obtained.
【００１３】〔比較例３〕ポリ塩化ビニルにＤＯＰ、Ｅ
ＯＰ、Ca-Zn ステアレート、ＴＮＰＰを配合した表１に
示すような塩化ビニル樹脂組成物を混練してペレットを
得、このペレットから実施例１と同様のシートを成形
し、実施例１と同様の色測定を行ったところ、表２に示
すような結果が得られた。Comparative Example 3 DOP and E were added to polyvinyl chloride.
A vinyl chloride resin composition containing OP, Ca-Zn stearate, and TNPP as shown in Table 1 was kneaded to obtain pellets, and a sheet similar to that of Example 1 was formed from the pellets. When the color measurement was performed, the results shown in Table 2 were obtained.
【００１４】[0014]
【表１】 [Table 1]
【００１５】[0015]
【表２】 [Table 2]
【００１６】〔抗菌効果の評価試験〕実施例１〜２、比
較例１〜３で得られたペレットを、一軸押出機を用いて
外径１．５５ｍｍ、内径１．０５ｍｍのカテーテル用チ
ューブを成形し、それらのチューブについて抗菌効果の
評価試験を行ったところ、表３のような結果が得られ
た。抗菌効果の評価試験は、大腸菌（Ｅ．Ｃｏｌｉ：Ｉ
ＦＯ−３３０１）を対称菌株として次に示すシェークフ
ラスコ改法により行った。対称菌株をニュートリエント
ブロス培地溶液中で３７℃、１８時間震盪培養（振幅４
ｃｍ、震盪数１２０回／分）し、次いでこの培養菌液を
ニュートリエントブロス培地に１／１００容量加え、同
様に６時間震盪培養し、得られた対数増殖期の菌液をニ
ュートリエントブロス培地を１／５００容量含む生理食
塩水（稀釈液）により１０4 個／ｍｌオーダーに稀釈し
て試験菌液を作成した。次に、この試験菌液１０ｍｌを
１００ｍｌ三角フラスコに採り、この三角フラスコに各
チューブを長さ２ｃｍに切断して表面積が５０ｃｍ2 に
なる量を投入する。次に、三角フラスコを２５℃の恒温
水槽中で３時間および２４時間震盪（振幅４ｃｍ、震盪
数１２０回／分）した後、これを混釈平板培養法により
培養し、生菌数を測定した。測定結果を表３に示す。表
２、３から銀イオン担持無機抗菌剤を含有し、かつ亜リ
ン酸エステルを含有しない塩化ビニル樹脂組成物からな
る実施例１、２の成形品は、経時的な変色が著しく改善
されるとともに、抗菌効果も維持されていることが分か
る。[Evaluation Test of Antibacterial Effect] The pellets obtained in Examples 1 and 2 and Comparative Examples 1 to 3 were molded into a catheter tube having an outer diameter of 1.55 mm and an inner diameter of 1.05 mm using a single screw extruder. Then, when an evaluation test of the antibacterial effect was performed on those tubes, the results shown in Table 3 were obtained. The evaluation test of the antibacterial effect was performed by using E. coli (I.
FO-3301) as a symmetric strain by the following shake flask modification. The symmetric strain is shake-cultured in a nutrient broth medium solution at 37 ° C. for 18 hours (amplitude: 4).
cm, shaking rate: 120 times / min), then add 1/100 volume of this culture to a nutrient broth medium, shake culture in the same manner for 6 hours, and transfer the resulting logarithmic growth phase bacterial solution to a nutrient broth medium. Was diluted to the order of 10 4 cells / ml with a physiological saline solution (diluent) containing 1/500 volume to prepare a test bacterial solution. Next, 10 ml of the test bacterial solution is taken in a 100 ml Erlenmeyer flask, and each tube is cut into a length of 2 cm and an amount having a surface area of 50 cm 2 is put into the Erlenmeyer flask. Next, the Erlenmeyer flask was shaken (amplitude: 4 cm, shaking rate: 120 times / minute) in a constant temperature water bath at 25 ° C. for 3 hours and 24 hours, and then this was cultured by the pour plate culture method, and the number of viable bacteria was measured. . Table 3 shows the measurement results. From Tables 2 and 3, the molded articles of Examples 1 and 2 comprising the vinyl chloride resin composition containing the silver ion-carrying inorganic antibacterial agent and not containing the phosphite ester have significantly improved discoloration over time, and It can be seen that the antibacterial effect is also maintained.
【００１７】[0017]
【表３】 [Table 3]
【００１８】[0018]
【発明の効果】以上説明してきたことから明らかなよう
に、本発明の医療用具は、抗菌効果が損なわれることな
く、経時的な変色が著しく改善されている。As is apparent from the above description, the medical device of the present invention has significantly improved discoloration with time without impairing the antibacterial effect.
Claims (3)
菌剤を含有し、かつ亜リン酸エステルを含有しない、塩
化ビニル樹脂組成物からなる医療用具。1. A medical device comprising a vinyl chloride resin composition containing an antibacterial agent comprising silver ions carried on an inorganic carrier and containing no phosphite.
ビニル構造単位を有する請求項１に記載の医療用具。2. The medical device according to claim 1, wherein the vinyl chloride resin has a vinyl chloride structural unit of 50% by weight or more.
酸、リン酸ジルコニウム、多孔質ガラス、多孔質シリ
カ、アルミナ、ポリリン酸アルミニウム、ヒドロキシア
パタイト、チタニア、シリカゲルの群から選ばれる少な
くとも１つである請求項１に記載の医療用具。3. The inorganic carrier is at least one selected from the group consisting of zeolite, aluminosilicate, zirconium phosphate, porous glass, porous silica, alumina, aluminum polyphosphate, hydroxyapatite, titania, and silica gel. 2. The medical device according to 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9208739A JPH1147261A (en) | 1997-08-04 | 1997-08-04 | Medical instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9208739A JPH1147261A (en) | 1997-08-04 | 1997-08-04 | Medical instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH1147261A true JPH1147261A (en) | 1999-02-23 |
Family
ID=16561289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9208739A Pending JPH1147261A (en) | 1997-08-04 | 1997-08-04 | Medical instrument |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH1147261A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006120135A1 (en) * | 2005-05-10 | 2006-11-16 | Ciba Specialty Chemicals Holding Inc. | Antimicrobial porous silicon oxide particles |
| JP2008023071A (en) * | 2006-07-21 | 2008-02-07 | Kaneka Corp | Medical drain tube and production method thereof |
| JP2009513203A (en) * | 2005-10-28 | 2009-04-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Inhaler with mouthpiece having microbiological protection function |
| US9005355B2 (en) | 2010-10-15 | 2015-04-14 | Bunge Amorphic Solutions Llc | Coating compositions with anticorrosion properties |
| US9078445B2 (en) | 2012-04-16 | 2015-07-14 | Bunge Amorphic Solutions Llc | Antimicrobial chemical compositions |
| JP2015520732A (en) * | 2012-04-16 | 2015-07-23 | ブンゲ アモルプヒク ソルトイオンス エルエルシー | Antibacterial chemical composition |
| US9155311B2 (en) | 2013-03-15 | 2015-10-13 | Bunge Amorphic Solutions Llc | Antimicrobial chemical compositions |
| US9371454B2 (en) | 2010-10-15 | 2016-06-21 | Bunge Amorphic Solutions Llc | Coating compositions with anticorrosion properties |
| US9611147B2 (en) | 2012-04-16 | 2017-04-04 | Bunge Amorphic Solutions Llc | Aluminum phosphates, compositions comprising aluminum phosphate, and methods for making the same |
| CN108976664A (en) * | 2018-07-20 | 2018-12-11 | 王晚秀 | A kind of food fresh keeping preparation method for packing membrane material |
-
1997
- 1997-08-04 JP JP9208739A patent/JPH1147261A/en active Pending
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008544953A (en) * | 2005-05-10 | 2008-12-11 | チバ ホールディング インコーポレーテッド | Antibacterial porous silicon oxide particles |
| WO2006120135A1 (en) * | 2005-05-10 | 2006-11-16 | Ciba Specialty Chemicals Holding Inc. | Antimicrobial porous silicon oxide particles |
| JP2009513203A (en) * | 2005-10-28 | 2009-04-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Inhaler with mouthpiece having microbiological protection function |
| JP2008023071A (en) * | 2006-07-21 | 2008-02-07 | Kaneka Corp | Medical drain tube and production method thereof |
| US9371454B2 (en) | 2010-10-15 | 2016-06-21 | Bunge Amorphic Solutions Llc | Coating compositions with anticorrosion properties |
| US9005355B2 (en) | 2010-10-15 | 2015-04-14 | Bunge Amorphic Solutions Llc | Coating compositions with anticorrosion properties |
| US9840625B2 (en) | 2010-10-15 | 2017-12-12 | Bunge Amorphic Solutions Llc | Coating compositions with anticorrosion properties |
| JP2015520732A (en) * | 2012-04-16 | 2015-07-23 | ブンゲ アモルプヒク ソルトイオンス エルエルシー | Antibacterial chemical composition |
| US9611147B2 (en) | 2012-04-16 | 2017-04-04 | Bunge Amorphic Solutions Llc | Aluminum phosphates, compositions comprising aluminum phosphate, and methods for making the same |
| US9801385B2 (en) | 2012-04-16 | 2017-10-31 | Bunge Amorphic Solutions Llc | Antimicrobial chemical compositions |
| US9078445B2 (en) | 2012-04-16 | 2015-07-14 | Bunge Amorphic Solutions Llc | Antimicrobial chemical compositions |
| US9155311B2 (en) | 2013-03-15 | 2015-10-13 | Bunge Amorphic Solutions Llc | Antimicrobial chemical compositions |
| US9955700B2 (en) | 2013-03-15 | 2018-05-01 | Bunge Amorphic Solutions Llc | Antimicrobial chemical compositions |
| CN108976664A (en) * | 2018-07-20 | 2018-12-11 | 王晚秀 | A kind of food fresh keeping preparation method for packing membrane material |
| CN108976664B (en) * | 2018-07-20 | 2020-11-24 | 东莞世皓新材料生物科技有限公司 | Preparation method of packaging film material for food preservation |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4663077A (en) | Microbiocidal compositions comprising an aryl alkanol and a microbiocidal compound dissolved therein | |
| JPH1147261A (en) | Medical instrument | |
| US4761247A (en) | Phenol-stabilized microbiocidal compositions | |
| AU678609B2 (en) | A novel antifungal composition | |
| EP0168949B2 (en) | Microbiocidal compositions and processes for imparting microbiocidal properties to polymer compositions | |
| EP0732052B1 (en) | An antimicrobial polymer composition | |
| US6294183B1 (en) | Antimicrobial resin composition and antimicrobial resin molded article comprising same | |
| EP0138147B1 (en) | Citrate-ester plasticized pvc blood containers | |
| US5468738A (en) | Fungicide and its use | |
| JP3880157B2 (en) | Antibacterial nonwoven fabric | |
| IL75116A0 (en) | Beta-carboline-3-carboxylic acid derivatives,process for the preparation thereof and pharmaceutical compositions containing the same | |
| US3833520A (en) | Method of controlling microbial growth in polyvinyl halide resin compositions | |
| EP0400454A2 (en) | Stabilized phosphite compositions | |
| US4711914A (en) | Microbiocidal compositions comprising an aryl alkanol and a microbiocidal compound dissolved therein | |
| JPH08157637A (en) | Antimicrobial porous polymer membrane | |
| JPS5933343A (en) | Vinyl chloride resin composition | |
| US4758609A (en) | Microbiocidal compositions comprising an aryl alkanol and a microbiocidal compound dissolved therein | |
| JP2001040273A (en) | Antibacterial coating and antibacterial product | |
| US4895877A (en) | Microbiocidal compositions comprising an aryl alkanol and a microbiocidal compound dissolved therein | |
| EP0330151A2 (en) | Bag for the storage of blood platelets | |
| US4721736A (en) | Microbiocidal compositions comprising an aryl alkanol and a microbiocidal compound dissolved therein | |
| US5028619A (en) | Microbiocidal compositions comprising an aryl alkanol and a microbiocidal compound dissolved therein | |
| JP3154365B2 (en) | Antibacterial resin molding | |
| HU182535B (en) | Process for preparing bacterial cell aggregates | |
| KR20010106752A (en) | Film having antibacterial agent and deodorizer |