JPH11354A - Heating element - Google Patents

Abstract

PROBLEM TO BE SOLVED: To check and restrain the propagation of bacteria and the true fungi by housing a heating composition heating under the existence of air in a gas permeable housing bag, constituting a heating element by sealing this housing bag in an airtight bag, and holding an antibacterial agent in the housing bag. SOLUTION: At least a part of a flat gas permeable inner bag 1 having gas permeable small holes or a micropore group is formed as a gas permeable surface, and a heating composition 2 composed of metallic powder such as iron powder, activated carbon, water, a water retentive agent, salt or the like is sealed in this inner bag 1. An organic compound, an antibacterial agent derived from a natural material and an antibacterial agent such as an inorganic compound are also included in the inner bag 1. This inner bag 1 is sealed in an airtight outer bag 3, and a necessary heating element is constituted. In this case, a nontransferable pressure sensitive adhesive layer 4 composed of an ordinary pressure sensitive adhesive substance mainly composed of rubber or the like is formed on a surface of the inner bag 1 when necessary, and this is covered with releasable paper 5, or an antislipping layer may be formed on the surface of the inner bag 1 instead of the pressure sensitive adhesive layer.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a heating element holding an antibacterial agent. More specifically, the present invention relates to a heating element capable of inhibiting and suppressing the growth of bacteria and fungi (mold). As used herein, the term “antibacterial agent” is a concept meaning a substance that inhibits or suppresses the growth of bacteria and / or fungi.

[0002]

2. Description of the Related Art Conventionally, a heat-generating composition which generates heat in the presence of air is housed in an air-permeable storage bag (inner bag), and the inner bag is impermeable to air. bag)
Heating elements packaged with are known. As this heating element, a non-transferable pressure-sensitive adhesive layer is provided on one side of the inner bag, so that it can be used as a disposable body warmer of the so-called pasting type, and other than those that warm the limbs and waist, a small size for warming the soles of the feet A light-weight disposable body warmer has been proposed.

[0003] When these heating elements are applied, they are heated and sweating and metabolism are promoted, so that an environment where bacteria and fungi easily grow in terms of temperature, humidity and nutrient sources is created. The optimal growth temperature of bacteria is 30-38 ° C, and the optimal growth temperature of fungi is 2
0-35 ° C. Bacteria are, for example, sweat attached to fibers,
Using sebum, dirt, etc. as a nutrient source, generally every 20 minutes
Cell division is repeated at a rapid rate of twice and proliferates in a short time. It is known that decomposition products produced during this growth cause malodor, and about 50 types of pathogenic bacteria that cause disease among bacteria have been discovered. Fungi are easy to grow in high humidity (about 60-90%). When proliferated, the fungi not only impair the aesthetic appearance, but also cause fungal infections such as fungal infections, fungal allergy, and fungal intoxication on the human body. May have adverse effects. No measures against such bacteria and fungi have been taken in conventional heating elements.

[0004] In view of the above circumstances, an object of the present invention is to provide a heating element having an antibacterial and deodorant action and an antifungal action.

[0005]

The heating element of the present invention contains a heat-generating composition which generates heat in the presence of air in a gas-permeable storage bag, and the storage bag is sealed in an air-tight bag. The heating element is characterized in that the storage bag holds an antibacterial agent.

[0006]

BEST MODE FOR CARRYING OUT THE INVENTION The heating element of the present invention is a disposable body warmer (for example, a warmer for warming limbs, waist, etc., which may be used as a warmer for sticking or not sticking, or a thin type warmer for soles of feet). Medical heating elements having a heating effect (including, for example, a dry hot compress method such as a medical heating element of a sticking or non-sticking type which is used for heating and / or keeping a local portion of a human or an animal, etc.) ), And a heating element used for food, beverage, etc. for the purpose of keeping warm.

Hereinafter, a heating element of the present invention will be described with reference to the accompanying drawings.

FIG. 1 is a cross-sectional view of one embodiment of an antibacterial agent-containing heating element of the present invention, FIG. 2 is a cross-sectional view of another embodiment, and FIG. 3 is a cross-sectional view of another embodiment. is there.

In FIG. 1, reference numeral 1 denotes a flat gas-permeable inner bag having small holes or fine holes. The inner bag 1
At least a part thereof is a breathable surface. That is, one surface (the lower surface in FIG. 1) may be a gas-permeable surface and the other surface may be a gas-impermeable surface, or both surfaces may be gas-permeable surfaces. Further, of the one surface, a part may be a permeable surface and the rest may be a non-permeable surface.

The air permeability of the inner bag 1 is not particularly limited, but the size of the air hole may be any size as long as the contents are not spilled, for example, about 0.5 mm or less. As long as the exothermic composition can generate heat, it is not particularly limited in the present invention,
Usually, the value measured by the method A (humidity sensor method) defined in JIS K 7129 is 50 to 3000 g /
m ² · day, preferably 200 to 1300 g /
m ² · day, particularly preferably 300 to 1000 g /
m ² · day.

The material of the inner bag 1 is not particularly limited, but it is preferable that the material is not fuzzy, soft, strong, has a stable quality, and has heat sealability.
For example, a laminate (laminate) of a nonwoven fabric and a polyethylene film is usually used.

The antibacterial agents contained in the inner bag 1 are roughly classified into organic compounds, antibacterial agents derived from natural products, and inorganic compounds. Specific examples of the organic compound include, for example, cationic and betaine-type (carboxybetaine, sulfobetaine) including quaternary ammonium salts such as benzalkonium chloride and benzethonium chloride, aminocarboxylate, imidazolium Surfactants such as amphoteric surfactants including imidazoline derivatives such as betaine and lecithin; aldehydes such as formaldehyde (formalin) and glutaraldehyde; phenol (carbonic acid), cresol, picric acid, xylenol, resorcinol, pyrogallol, β -Phenolic compounds such as naphthol, thymol, biosol (isopropylmethylphenol), and catechol; imidazole fungicides such as thiazolylbenzimidazole; chlorhexidine diacetate, chlorhexidi Dihydrochloride, chlorhexidine 2 gluconate, guanidine fungicide such as polyhexamethylene biguanide hydrochloride; and benzoic acid, sorbic acid, dehydroacetic acid, propionic acid, and organic acids such as p-hydroxybenzoic acid esters.
Specific examples of the antibacterial agent derived from the natural product, for example,
Wasabi essential oil or mustard extract containing allyl isothiocyanate as a main component; hinokitiol; chitosan; pectin hydrolyzate; polylysine; protamine (mushroom protein); bamboo extract such as moso bamboo containing quinone derivative; Bamboo-derived antibacterial substances such as bamboo; combination of nisin and a hydrophilic surfactant; bakchiol;
I proteins, bactericidal peptides such as CAP57, CAP37, azurosin, defensin, etc .; barley extract; coffee plant. Specific examples of the inorganic compound include, for example, a silver-supported inorganic antibacterial agent in which silver is supported on an inorganic carrier such as zeolite, hydroxyapatite, zirconium phosphate, silica, alumina, and aluminum polyphosphate; a copper compound; Zinc; a cobalt alloy; and a photocatalyst such as a semiconductor (eg, titanium oxide).

The antibacterial agent may be used alone or in combination, and is contained in one or both surfaces of the inner bag 1 partially or entirely.

[0014] The antimicrobial agent is contained in the inner bag in a manner commonly practiced in the art. Examples of the inner bag or a layer constituting the inner bag holding an antibacterial agent include, for example, a nonwoven fabric immersed in an antibacterial agent-containing liquid and dried or a laminated body of a nonwoven fabric coated with an antibacterial agent and dried with a polyethylene film; A laminate of a polyethylene film and a nonwoven fabric coated with an agent and dried, or a laminate of a polyethylene film and a nonwoven fabric obtained by mixing or kneading an antibacterial agent and polyethylene are exemplified.

The content of the antibacterial agent may be an amount usually used in the art, but is preferably 0.1 to 5 parts by weight, more preferably 0.5 part by weight, per 100 parts by weight of the inner bag.
３3 parts by weight.

The bacteria and fungi whose growth is inhibited or suppressed depend on the antibacterial agent used, and include, for example, Gram-positive bacteria such as Staphylococcus aureus, and Gram-negative bacteria such as Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae. Fungi such as black mold and blue mold.

As a method of adjusting the air permeability of the air permeable surface of the inner bag 1, there can be mentioned a method of subjecting a sheet or a film having fine continuous pores to an appropriate heat-sealing treatment. Specifically, for example, the heat-sealed portion can be evenly dispersed in a sheet or a film having uniform continuous pores of 1 to 50 μm, or the whole can be applied to limit the air permeability. The air permeability may be adjusted by performing a perforation process.

In addition, a resin film provided with fine air holes can be laminated on the nonwoven fabric to restrict air permeability.

The size of the inner bag 1 is not particularly limited in the present invention, but usually, a size in the range of 4 × 6 cm to 15 × 20 cm can be used.

The exothermic composition 2 sealed in the inner bag 1 includes:
For example, metal powder such as iron powder (preferably metal powder treated with sulfur or a sulfur-containing compound), activated carbon, water, water retention agent (wood flour, vermiculite, diatomaceous earth, perlite, silica gel, alumina, water absorbent resin, etc.) ), Salt and the like, but are not limited thereto.

FIG. 2 shows another embodiment of the heating element according to the present invention, in which a non-transferable pressure-sensitive adhesive layer made of a normal pressure-sensitive adhesive material mainly composed of rubber or the like is formed on the surface of the inner bag 1. 4 are formed.

The pressure-sensitive adhesive layer 4 may be provided on one entire surface of the inner bag 1 or partially provided so as to form an appropriate pattern such as a stripe pattern, a lattice pattern, a polka dot pattern, or the like. Is also good. The non-transferable pressure-sensitive adhesive layer 4 is formed after the heat generating composition 2 is filled in the inner bag 1.

In the embodiment shown in FIG.
A release paper 5 is coated on the top, and when used, the release paper 5 is peeled off, and the inner bag 1 is attached to a desired portion using the non-transferable adhesive layer 4.

FIG. 3 shows still another embodiment of the heating element of the present invention. In the inner bag 1, the surface on which the anti-slip layer 6 described later is formed has a thickness of 10 μm to 100 μm.
A laminate of a film made of polyester or polypropylene such as polyethylene terephthalate to a certain degree and a woven fabric, nonwoven fabric or paper can be suitably used.
When this laminate is used, the non-slip layer 6 is formed on the surface of the nonwoven fabric or the like as an outer layer.

[0025] The size of the inner bag 1 is not particularly limited in the present invention, but a size that can be inserted into shoes can be used. The shape may be circular, elliptical, or rectangular, but it is preferable to adopt a tongue or horseshoe shape corresponding to the shape of the sole of the foot.

The non-slip layer 6 may be formed on the entire surface of one side, or may be partially formed so as to exhibit various patterns such as a polka dot pattern or a striped pattern in order to enhance the slip prevention effect.

Examples of the anti-slip layer 6 include the following.

(1) A solution or dispersion of a resin or elastomer, or a plastisol is applied uniformly or in a pattern on the surface of the material of the inner bag 1, and dried.

Examples of the resin and elastomer include soft vinyl chloride resin, natural rubber, styrene-butadiene rubber, isoprene rubber, chloroprene rubber, urethane rubber and the like.

(2) A hot melt type resin material is applied uniformly or in a pattern to the surface of the material of the inner bag 1 by a hot melt coating method.

Examples of the hot melt type resin material include ethylene-vinyl acetate copolymer, hydrolyzate of ethylene-vinyl acetate copolymer, ethylene-acrylic acid copolymer, ethylene acrylate copolymer,
A hot melt adhesive mainly composed of a polyamide resin, a polyester resin or the like can be used.

(3) A hot-melt resin is extruded and laminated on the surface of the material of the inner bag 1.

The heat-meltable resin is preferably a resin having good tackiness, such as ethylene-methyl methacrylate copolymer (EMMA).

(4) The surface of the material of the inner bag 1 is uniformly or patterned coated or impregnated with a foamable resin composition, and then foamed to form a resin foam layer.

(5) A synthetic resin film is laminated on the surface of the material of the inner bag 1.

Examples of the foamable resin composition include a polyurethane resin composition using water or a low-boiling point neutral liquid as a foaming agent. A capsule obtained by mixing a capsule containing a foaming agent (a volatile solvent such as isobutane) in a resin core such as an acrylic resin (eg, a thermosetting acrylic resin such as a vinylidene chloride-acrylonitrile copolymer) with a binder resin. When this mixture is applied and foamed, an uneven surface can be formed.

In the above, a gravure coater or the like can be used to apply each resin material in a pattern.

In the case of a hot-melt adhesive or a soft vinyl chloride resin, the granular material is evenly sprayed on the surface of the material of the inner bag 1, and then heated to fix the material. Many protrusions can be formed on the surface of the material.

If such an anti-slip layer 6 is attached so as to be in contact with the inner surface of the shoe (the surface on which the sole of the foot is in contact), the desired portion can be warmed without the foot warmer moving.

The inner bag 1 is sealed in an air-tight or air-impermeable outer bag 3 made of a non-porous film such as polyethylene or polypropylene.

Hereinafter, the present invention will be described in more detail with reference to examples. However, the examples are for explanation, and do not limit the scope of the present invention.

[0042]

【Example】

Example 1 2.0 parts by weight of silver-carrying inorganic particles were added to 100 parts by weight of nylon 6 polymer, and sufficiently stirred with a biaxial kneader to obtain a master polymer chip. A nonwoven fabric having a basis weight of 40 g / m ² and a fiber diameter of 2.1 denier was prepared from this chip by a spun bond method, and used as an inner bag for a warmer.

Test Example 1 (Bacterial Counting Method) Using the manual of the processing effect evaluation test for the antibacterial and deodorant processed product and the bacterial count measuring method (Textile Sanitation Processing Council, 1988), the bacterial count was determined as follows. Was performed.

The following bacteria were suspended in a sterilized liquid broth, and 0.2 ml of this solution was placed on a test piece taken from the nonwoven fabric of the inner bag for a warmer prepared by the method described in Example 1 in an amount of 0.2 g.
After inoculation and culturing at a temperature of 37 ° C. for 18 hours, the number of viable bacteria on the test piece before and after the taken out culture was measured, and the increase / decrease of the number of bacteria and the difference between the increase / decrease were calculated by the following formula.

Test organism: Staphylococcus aureus ( Staphylococcus aureus)
aureus ) ATCC 6538P (IFO 127
32) Klebsiella pneumoniae Klebsiella pneumoniae (Klebs
iellapneumoniae ) ATCC 4352 Escherichia coli ( Escherichia)
coli (IFO 3301) Pseudomonas aeruginosa ( Pseudo )
monasaeruginosa ) (IFO 308)
0) Test piece mass: 0.2 g Culture temperature / time: 37 ° C x 18 hours

[0046]

(Equation 1)

Criteria for Establishing the Test The difference between the logarithmic value of the number of bacteria after 18 hours of cultivation of the unprocessed sample and the logarithmic value of the number of bacteria immediately after inoculation is 2 or more.

Evaluation Criteria The difference between the logarithmic value of the number of bacteria after culturing for 18 hours of the unprocessed sample and the logarithmic value of the number of bacteria after culturing for 18 hours of the processed sample is 1.6 or more. That is, the difference in the increase / decrease in the number of bacteria is 1.6 or more.

[0049]

[Table 1]

[0050]

[Table 2]

[0051]

[Table 3]

[0052]

[Table 4]

Test Example 2 (Shake Flask Method) The antibacterial property was tested as follows by applying the shake flask method described in the processing evaluation test manual for antibacterial and deodorized products.

A suspension of the test bacteria (the number of bacteria is 1 billion or more / 1 ml) was poured into 0.75 g of the sample, and 330 rpm at 37 ° C.
m for 1 hour. The viable cell count after shaking and the viable cell count before shaking were measured. The rate of decrease in the number of bacteria after shaking (the rate of bacteria reduction) with respect to the number of bacteria before shaking was determined by the following formula. The inner bag of the present invention used as a sample was the same as in Test Example 1.

Test strain: Staphylococcus aureus ( Staphylococcus aureus)
aureus ) ATCC 6538P (IFO 127
32) Bacteria reduction rate (%) = (BA) / B × 100 A: Number of bacteria per ml in Erlenmeyer flask after shaking B: Number of bacteria per ml in Erlenmeyer flask before shaking The sterilization rate of the test (test with only the bacterial solution without adding the sample) is ±
Within 10%, the sterilization rate of unprocessed cloth is 30% or less. Evaluation criteria The difference between the sterilization rate of processed cloth and the sterilization rate of unprocessed cloth is 26% or more.

[0056]

[Table 5]

Test Example 3 (Hello Test, Fungal Resistance) A test (halo test method) for antibacterial properties was carried out as follows according to JIS L 1902.

A PDA agar medium was prepared by inoculating a bacterial dish with a 90-mm-diameter plate petri dish so as to have a bacterial concentration of 10 ⁶ cells / ml. A sterilized circular sample cloth having a diameter of 28 mm was gently pressed against the agar medium to bring it into close contact. 3 flat plates
The cells were cultured at 7 ° C for 18 to 24 hours. The band of inhibition around the sample cloth was observed from the back through the bottom of the plate medium, and the width of the band of inhibition was determined by the following formula. The test was performed on the inner bag of the present invention (same as in Test Example 1) and a non-processed cloth (data not shown).

Test bacterium: Trichophyton mentaglophides ( Trichophyton mentagroph)
ytes ) (IFO 6202) Inhibition band width = (diameter of inhibition band including sample cloth−diameter of sample cloth) / 2 Evaluation The inhibition band is observed in comparison with the control cloth.

[0060]

[Table 6]

A test was conducted for fungal resistance according to the JIS Z 2911 6.2.2 wet method.

A test piece cut to a size larger than 50 × 50 mm was placed in a 1000 ml beaker having a rubber tube inserted at the bottom, and water was poured at 500 to 1000 ml / min for 24 hours. The test piece was taken out, further cut to 50 × 50 mm, shaken in purified water in another 1000 ml beaker, and washed again by replacing the purified water. The washed test piece was removed and placed so as to adhere to the center of the plate medium. 1 ml of the mixed spore suspension containing the following fungal spores is evenly spread on the culture surface and the test piece surface,
With the lid closed, the cells were cultured at a temperature of 28 ± 2 ° C. for 2 weeks, and the growth state of the bacterial system was observed. The inner bag of the present invention used as a test piece was the same as in Test Example 1.

Test bacterium: Aspergillus niger (FERM) (FERM)
S-1) Blue mold Penicillium citrinium ( Penicil)
limcitrinum ) (FERM S-5) Chaetomium globosum ( Chaetomium g )
lobosum ) (FERM S-11) Myrothecium bercaria ( Myrothecium )
verrucaria ) (FERM S-13) Medium used: JIS inorganic salt agar medium

[0064]

[Table 7]

[0065]

As described above, in the heating element of the present invention, since the antibacterial agent is held in the inner bag, the growth of bacteria and fungi can be inhibited and suppressed.

[Brief description of the drawings]

FIG. 1 is an explanatory sectional view of one embodiment of a heating element of the present invention.

FIG. 2 is an explanatory sectional view of another embodiment of the heating element of the present invention.

FIG. 3 is an explanatory sectional view of still another embodiment of the heating element of the present invention.

[Description of Signs] 1 Inner bag 2 Exothermic composition 3 Outer bag 4 Adhesive layer 5 Release paper 6 Non-slip layer

Claims (3)

[Claims] 1. A heating element in which a heat-generating composition that generates heat in the presence of air is stored in a breathable storage bag, and wherein the storage bag is sealed in an airtight bag. A heating element characterized in that an antibacterial agent is held in a bag. 2. The heating element according to claim 1, wherein an adhesive layer is formed on at least one side of the storage bag. 3. The heating element according to claim 1, wherein an anti-slip layer is formed on at least a part of the storage bag.