JPH11349603A - Glycogen colloid particle aggregate - Google Patents

Abstract

PROBLEM TO BE SOLVED: To improve excellent properties of imparting cloud, sliding, or the like, by aggregating glycogen with a nonionic surfactant. SOLUTION: This particle aggregate is obtd. by coexisting a glycogen colloid particle and a nonionic surfactant in a medium. As the medium, usually an aq. medium is used. As the glycogen, a glycogen derived from a plant (phytoglycogen) such as corn, or the like, is pref. As the nonionic surfactant, a polyalkylene glycol type is pref. and among others, a polyethylene glycol type is pref. As glycogen concn. in the aq. medium, not higher than 30 wt.% is pref. This aggregate is used as a clouding agent and a sliding agent, e.g. cosmetics, quasi-drugs medicines, drinks, food, or the like.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

[0001] The present invention relates to an aggregate of glycogen colloid particles. This aggregate has the potential to be used in many fields including, for example, use in cosmetics, quasi-drugs, food and drink products.

[0002]

2. Description of the Related Art Glycogen is a nonionic polysaccharide, which is dispersed in an aqueous medium as extremely stable colloid particles (some states are described as "dissolved").
It is known that this dispersion is slightly turbid or cloudy depending on the concentration, and exhibits an elegant opal color that looks blue or red depending on the viewing angle. The dispersion has a viscosity (20 ° C.) of about 100 (mPa · s) or less even when the glycogen concentration is as high as about 20% by weight, for example, and is lower than that of a normal water-soluble polymer compound. It also has the characteristic that the viscosity is extremely low and, for that reason, almost no tackiness is felt.

[0003] In general, articles used, displayed, and stored in liquid or gel form, such as cosmetics (including quasi-drugs) and foods and drinks, are given a luxurious appearance by giving the articles various turbidities. In order to enhance the commercial value of the product, to give an image of natural nature, and to further emphasize it.
Specifically, in cosmetics (lotion, bath agent, etc.), food and drink (juice, powdered shellfish absorptives, etc.), for example, water-insoluble inorganic fine particles, metallic soap, oils and fats emulsion, synthetic resin emulsion, etc. A method of appropriately selecting according to the use, blending in the above-described article, and dispersing and suspending the article is performed to impart turbidity. All of these methods can be carried out at low cost and are economical, but sedimentation and roughening due to high specific gravity, aggregation and large particles, remaining on skin with a slimy feeling, coarse droplets due to coalescence of particles, Many problems are likely to occur, such as separation, oxidative deterioration, and odor caused by raw materials or raw materials remaining in trace amounts, and the field of application is sometimes restricted by law.

When glycogen having the above-mentioned preferable characteristics is used, the turbidity agent is excellent without causing the above-mentioned problems, but in order to impart the same degree of turbidity, it is necessary to use the conventional turbidity. The disadvantage is that a larger amount (higher concentration) is required than the method of turbidity. In addition, for example, pressurization for an electric razor is usually performed by using a spherical plastic fine powder (nylon, cross-linked polymethyl methacrylate, etc.) or an insoluble inorganic fine powder (talc, calcium carbonate, etc.) as a slipping agent in a water-ethanol medium. And the like are suspended therein, and have a quick drying property. This lotion is intended to be applied to a portion where a beard is to be shaved to smooth the electric razor during the shaving by the electric razor and to improve the feel of the skin after shaving. When glycogen is used as a slip agent for this pressurized lotion, the lotion is almost as good as the one using spherical plastic fine powder as a slip agent in almost all aspects such as slipping and shaving during shaving, and feeling after shaving. However, there is a disadvantage that the skin slips after shaving is slightly lower.

[0005]

SUMMARY OF THE INVENTION It is an object of the present invention to provide a glycogen colloid particle aggregate having excellent properties such as turbidity imparting property and slipperiness.

[0006]

The present inventors have conducted various studies on the behavior of glycogen colloid particles and dispersions thereof. As a result, the present inventors have found that glycogen colloid particles form aggregates with a nonionic surfactant, and that the formation of aggregates is improved. The present inventor has found that the aggregate has excellent properties and has completed the present invention.
That is, the present invention provides a glycogen colloid particle aggregate obtained by aggregating glycogen with a nonionic surfactant, and a turbidity agent and a slipping agent containing the aggregate.

[0007]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail.
The glycogen colloid particle aggregate of the present invention is obtained by allowing glycogen colloid particles and a nonionic surfactant to coexist in a medium. As the medium, an aqueous medium is usually used. Depending on the ratio of glycogen to nonionic surfactant and the concentration of each in a system containing these, the aggregates can be in various states, for example, from a state of being stably dispersed and suspended in a medium to a state of sedimentation. There are things. These agglomerates may be separated from the medium and dried, but may be used in a state of being dispersed and suspended in the medium or in a state of sedimentation separation, or in a state of a dried undried cake or a concentrated dispersion suspension. It is often convenient to use it in a state where it is not used.

The glycogen used in the present invention is usually D
-A glucose unit having a chain mainly composed of α-1,4-glucosidic bonds as a main chain and a branch,
In the main chain, a plurality of branches in which D-glucose units are α-1,4-glucosidic bonds are formed at the branch points at α-1,6-glucosides.
It has a glucosidic bond, and most of the branches have further branches. Glycogen having some α-1,3-glucosidic bond as long as it has such structural characteristics is also included in the glycogen.

[0009] Glycogen is a branch having many branches.
It is a non-ionic polysaccharide having a linear structure. Glycogen is
Because it is derived from natural materials such as animals and plants,
There may be fluctuations depending on the type, collection time, location, etc.
Usually, the average molecular weight is 10⁷-10 ⁹Degree and average chain length
About 10 to 14, the limit of about 45%
Therefore, the degree of branching is much higher than the similar substance amylopectin.
No. Glycogen solution is a very stable molecular colloid
It becomes a dispersion. And glycogen was highly branched
High molecular weight compared to other polysaccharides, probably because of spherical molecules
However, the viscosity of the aqueous solution is low.
The resulting glycogen film is brittle and easily breaks,
It becomes fine powder and granules.

Glycogen is a storage polysaccharide that is found abundantly in animal cells, especially in liver, muscle, leukocytes and the like, and is also present in plants such as corn. Approximately 1% or less, is also contained in the skin, and is consumed as an energy source.
Glycogen is water-soluble (colloidally dispersible) and insoluble in most organic solvents, so it is extracted from animals and plants containing glycogen, for example, with water, and ethanol is added thereto while stirring the solution to obtain a viscous solution. Glycogen microparticles are suspended or precipitated without undergoing a dense gel state. The fine particles thus obtained are purified, for example, by repeatedly dissolving in water and precipitating with ethanol, and then subjected to operations such as deliquoring and drying to obtain fine powders which are usually white to yellow-brown and almost tasteless.

Glycogen has different odors and colors depending on the raw materials used to obtain the same. Particularly, those produced from animals have remarkable unpleasant odors and colorings. The purification treatment is usually performed elaborately, but not sufficiently. In this case, the branch which is a characteristic structure of glycogen is dropped off, and further, the main chain is liable to be broken. Therefore, in the present invention, ease of purification,
From the viewpoint of the odor and color of the purified product, odorless, white or slightly pale yellowish-white plant-derived glycogen (phytoglycogen) derived from corn or the like is preferably used.

The surfactant used in the present invention is a nonionic surfactant, for example, a polyalkylene glycol type nonionic surfactant (higher alcohol, alkylphenol, fatty acid, polyhydric alcohol fatty acid ester, higher alcohol). Alkylamines, fatty acid amides, ethylene oxide adducts of fats or polypropylene glycols, etc.), polyhydric alcohol type nonionic surfactants (glycerol, pentaerythritol, sorbitol and sorbitan, or fatty acid esters of sucrose,
Alkyl ethers of polyhydric alcohols, fatty acid amides of alkanolamines, etc.), high molecular weight nonionic surfactants (polyvinyl alcohol and water-soluble or water-dispersible modified products thereof, water-soluble polyoxyalkylene-modified silicone compounds) Etc.). The nonionic surfactant is appropriately selected from one or a combination of two or more of those which are preferable depending on the purpose of use and use of the obtained aggregate, and polyalkylene glycol-type surfactants are preferable. Type is more preferred.

To obtain a large coagulation effect with a small amount of a surfactant, a nonionic surfactant having a high HLB, such as a polyoxyethylene-based nonionic surfactant, has a polyoxyethylene chain length. Are long and the hydrocarbon chain length is short. Therefore, when glycogen colloid particle aggregates are obtained in the form of a precipitate, for example, HLB is used.
It is advantageous to use nonionic surfactants with a high molecular weight. The nonionic surfactant having a high HLB has a cloud point of 10%.
When the cloud point is 100 ° C. or lower, a lower HLB can obtain a larger aggregation effect with a smaller amount of the surfactant. In order to finely adjust the amount of the surfactant used, as in the case where the turbidity is increased but the aggregated particles do not settle and are suspended in the medium, the correspondence between the HLB and the cloud point is required. The relationship is easy to use a nonionic surfactant having an inverse correlation to the above, and this may be combined with another nonionic surfactant.

The ratio of glycogen to surfactant when coagulating glycogen with a nonionic surfactant is appropriately selected depending on the desired properties of the obtained aggregate, for example, stable dispersibility, easy sedimentation, and the like. can do. Although the aqueous solution of glycogen has a lower viscosity than other water-soluble polymers, it may gel at a high concentration. Therefore, the concentration of glycogen in the aqueous medium in the above case is about 30% by weight or less. And more preferably about 0.5 to 20% by weight. An arbitrary substance can coexist with a system for obtaining the aggregate of the present invention or a substance obtained by dewatering and separating the aggregate, as long as it does not hinder the present invention, or can be mixed with an arbitrary substance. Preferred examples of these substances include water-soluble polyethylene oxide (including polyethylene glycol), nonionic polymer emulsions, and water-soluble alkyl cellulose / hydroxyalkyl cellulose / natural gums.

The technique of the present invention for coagulating and precipitating glycogen with a nonionic surfactant can be used instead of the means for precipitating glycogen with a water-soluble organic solvent or a water-soluble salt used in the production of glycogen. . In that case, a nonionic surfactant suitable for the use of the obtained glycogen, for example, in the case of food applications, those that can be used as food additives such as sucrose and glycerin esters, in the case of cosmetics It is preferable to select ones each of which is permitted to be used as a cosmetic raw material. In the case of the aggregate of the present invention, it is preferable to select a nonionic surfactant in consideration of its use as in the case described above.

[0016]

Industrial Applicability The present invention comprises a highly safe substance called glycogen, which gives a turbidity excellent in appearance and stability and gives a good touch to the skin with less use than glycogen. This provides an effect of providing a glycogen colloid particle aggregate that can be used. And
Due to these excellent effects, the glycogen colloid particle aggregates of the present invention are expected to have many uses including, for example, cosmetics, quasi-drugs, pharmaceuticals, beverages, and foods.

[0017]

[Embodiment 1 ] Samples Used in the Experiments (1) Phytoglycogen Dried sweet corn seeds (variety: golden cross bantam, collected 40 days after pollination) were added to a powder obtained by pulverizing a perchloric acid aqueous solution (3 times the weight of the powder). Perchloric acid concentration based on the total weight). This was homogenized with a homogenizer (25 ° C. × 5 minutes), purified by repeated dissolution and precipitation separation in water, and dried to obtain an almost white, odorless and tasteless phytoglycogen, which was used. For further details, see the Japanese Society of Agricultural Chemistry
7, Vol. 61, p. 455 (Biosci. Biotec)
h. Biochem. , 61, 455, 1997). (2) Nonionic surfactant Among the nonionic surfactants shown in Table 1, Emarex 720 [trade name, Icosaethylene glycol dodecyl ether, Nippon Emulsion Co., Ltd., C ₁₂ H ₂₅ (OC
₂ H ₄ ) ₂₀ OH]. The surfactants shown in Table 1 were used without purification, used as they were, and dissolved in water at room temperature to form micelles. HL added
The B value was calculated by the Griffin method. (3) Water The water used was distilled ion-exchanged water. (4) Measurement of light transmittance Double beam spectrophotometer (UV-210, manufactured by Shimadzu Corporation)
0 type), the transmittance of light having a wavelength of 600 nm was measured.

2. Experimental Method and Results An aqueous colloidal solution of phytoglycogen and a nonionic surfactant Emarex 720 (Table 1) were mixed with a total weight (G + S) of phytoglycogen weight (G) and surfactant weight (S). Medium concentration of 7.5% by weight (Example 1-7.
5) or 15% by weight (Example 1-15), and the ratio of the weight (G) of phytoglycogen to the total weight (G + S) of phytoglycogen and surfactant [G /
(G + S)] was placed in a glass test tube and sealed as shown in Table 2. The test tube was shaken well in a constant temperature water bath at 25 ° C., and then allowed to stand at a temperature of 25 ° C. for 1 hour to obtain a mixed solution sample. Immediately after shaking the sample, the transmittance of light having a wavelength of 600 nm was measured with a double beam spectrophotometer. Phytoglycogen (or surfactant)
For the control, the light transmittance of a liquid in which the amount of the surfactant (or phytoglycogen) in the mixed solution was replaced with a considerable amount of water was measured, and the value was also described. These results are shown in Table 2. Although the glycogen colloid liquid increases the turbidity due to the formation of aggregates by the addition and mixing of the nonionic surfactant, the colloid particles maintain a stable dispersion state,
Perhaps because the more the ratio of surfactant increases the aggregation,
The dispersion state became unstable and sedimented.

[0019]

[Table 1]

[0020]

[Table 2]

[0021]

[Table 3]

* 1 A nonionic surfactant "Emarex 750" was added to a solution obtained by dissolving and dispersing 9 parts by weight of phytoglycogen same as that used in Example 1 in 85 parts by weight of water.
(Pentacontaethylene cold decyl ether)
A phytoglycogen aggregate (precipitate) obtained by mixing 6 parts by weight, decanted with water, and then dewatered and separated to form a wet cake. Volatile content about 50% by weight.

Example 2 The mixture of (3) and (7) in Table 3 was gradually added to and mixed with (5) under slow stirring. Then, in this (4)
And (6) were added and mixed to obtain pressurized lotion.

Comparative Example 1 Table 3 (2) (same as that used in Example 1) was replaced with (7)
, And gradually added into the vigorously mixed (5). Next, (4) and (6) were added to and mixed with the mixture to obtain pressurized lotion.

Comparative Example 2 (1) [silicone oil / nylon powder = 1/1
0 (weight)], (5), (6) and (7) were mixed to obtain pressurized lotion.

After applying the pressurized lotion obtained in Example 2, Comparative Example 1 and Comparative Example 2 to the face, shaving was performed with an electric razor, in each case, the slip was good and the sled was smooth. The skin after shaving had no sliminess, was refreshing to the touch, and never whitened. Above all, those of Example 2 and Comparative Example 1 are excellent in moist feel and the sharpness of the blade of the electric razor was reduced by the repeated test in Comparative Example 2, whereas in each of these cases, There was almost no drop. In addition, Example 2 and Comparative Example 2 were excellent in terms of skin slippage after shaving.

Example 3 (1) In order to evaluate the performance of a phytoglycogen colloid particle aggregate as a turbidity agent, phytoglycogen 1
The result of examining the concentration of the aqueous solution of the phytoglycogen colloid particle aggregate in which turbidity equivalent to that of a 5% by weight aqueous solution is visually observed is as follows. The concentration in the case of phytoglycogen / Emalex 730 = 7/3 (weight ratio) is 1
It was 0.5% by weight. From the above results, it can be seen that phytoglycogen colloid particle aggregates can obtain the same turbidity effect at a lower concentration (small amount) than phytoglycogen. (2) Liquid A obtained by diluting the phytoglycogen colloid particle aggregate aqueous solution (concentration: 10.5% by weight) of the above (1) with water
(Concentration 3% by weight) and phytoglycogen liquid B (concentration 3% by weight) for comparison, titanium dioxide dispersion C (concentration 1% by weight), olive oil-based microemulsion D
(Concentration: 3% by weight) Each was filled and sealed in a transparent glass container so as to make up 50% by volume of the total volume of the container. Was evaluated by the following method. The evaluation criteria are as follows, and the results are shown in Table 4. <Evaluation criteria> ○ ……… Excellent. △ ……… Not very good. × ……… Not good.

[0028]

[Table 4]

The titanium dioxide dispersion C was used in a small amount as a sequestering agent using a small ball mill.
About 10% by weight of a titanium dioxide powder obtained by charging and dispersing titanium dioxide powder in stirred water containing ₂ % by weight / TiO ₂ ) and diluting it to 1% by weight with water. Using. From the above results, it can be seen that the phytoglycogen colloid particle aggregate has excellent stability as a turbidity agent.

Claims (4)

[Claims] 1. A glycogen colloid particle aggregate obtained by aggregating glycogen with a nonionic surfactant. 2. The aggregate of glycogen colloid particles according to claim 1, wherein the glycogen is derived from a plant. 3. A turbidity agent comprising the aggregate of glycogen colloid particles according to claim 1 or 2. 4. A slip agent comprising the aggregate of glycogen colloid particles according to claim 1 or 2.