JPH11267181A - Chemical container meltable on use - Google Patents

Abstract

PROBLEM TO BE SOLVED: To enable operation of mixing a desiccant and a dissolution liquid easily and in an aseptic manner with a simple structure. SOLUTION: This chemical container contains a container body 1 which is provided a dripping port 11 at the tip thereof and a hollow spike needle 14 at a bottom part 13 thereof and a cap 3 for sealing the dripping port 11. When the spike needle 14 is stuck through a rubber plug of a vial V, the chemical container is fixed on a mouth part of the vial by an engaging means 15 to make the chemical container communicate with the vial.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a ready-to-use drug solution container for dissolving a powdery or solid dry drug contained in a vial by a simple operation to make it a liquid.

[0002]

2. Description of the Related Art Conventionally, powdered or solid drugs that cause problems such as deterioration or loss of efficacy when stored in a liquid state have been used by being mixed immediately before use. Conventionally, this type of drug is stored in a separate container from the dissolving solution, and is transferred to a third container, for example, at the time of use, and the dissolving solution is injected into the third container and mixed, or the dissolving solution is sucked into a syringe or the like. In general, this is poured into a medicine container and mixed for use.
However, the transfer to the third container and the operation using a syringe are troublesome, and there is a problem in hygiene because there is a risk of contamination by bacteria.

[0003] To solve such a problem, a completely sterile system as disclosed in Japanese Patent Publication No. 61-501129, Japanese Patent Application Laid-Open No. 2-1277, Japanese Patent Application Laid-Open No. 3-37067, etc. has already been proposed. For the purpose of a manual dissolution operation, and those disclosed in JP-A-59-209535 and JP-A-62
No. 137056, Japanese Unexamined Patent Publication No. Hei 2-4375, Japanese Patent Publication No. Hei 2-26506, etc., cannot perform a completely aseptic operation, but can substantially select a combination of a drug and a dissolving solution. A device capable of aseptic operation has been proposed.

Japanese Patent Application Laid-Open No. 61-501129 discloses a capsule in which a capsule containing a drug container and a flexible container containing a solution are connected by a tube.
The communication container provided in the tube connects the medicine container and the flexible container, and the medicine and the solution are mixed aseptically. Japanese Patent Application Laid-Open No. 2-1277 discloses that a capsule containing a medicine container is connected to an opening of a solution container at a joint thereof, and a communication order regulating means is provided on the joint side of the capsule. With the communication means interposed, the lysis solution container is pierced after the drug container is pierced by the communication means, and the two containers are communicated, so that the drug and the lysis solution are aseptically mixed. Japanese Patent Application Laid-Open No. 3-37067 discloses that a medicine container, a communicating means, and a solution container are arranged in this order, sealed with a synthetic resin sheet, and between the medicine container and the solution container. A container supporting means is interposed from above the sheet, so that the two containers do not approach each other until the aseptic communication / mixing operation is performed.

On the other hand, Japanese Patent Application Laid-Open No. 59-209535 discloses a sealed first flexible container having a flexible wall member, and a fixed member penetrating through the wall member of the flexible container. Can,
A second container having a removable stopper, and a stopper removing member having a portion that engages with the stopper, the first container penetrating the second container through the second container, and engaging the stopper with the stopper removing member. A device is disclosed in which a stopper is removed from a second container together with a sealing barrier of a flexible container so that the contents of the two containers can be mixed. Japanese Patent No. 4375 discloses an improved version of the second container. In addition,
No. 26506 is disclosed in JP-A-59-2095.
This is an improvement of the device disclosed in Japanese Patent Publication No. 35-35.

[0006] In the former device disclosed in JP-T-61-501129 or the like, the drug container and the dissolving solution container are paired due to its configuration, so that only one drug is prepared. Although it has the drawback that it can be used, it enables complete aseptic operation, and the latter device disclosed in JP-A-59-209535 cannot perform complete aseptic operation. Since a substantially aseptic operation is possible and a combination of a drug and a dissolving solution can be arbitrarily selected, it is necessary in medical practice to appropriately use both as needed.

[0007]

However, the above-described conventional apparatus has many disadvantages such as a complicated mechanism and a problem in cost. The present invention has been made in view of the above circumstances, and has an object to provide a chemical solution container having a simple structure, capable of easily and aseptically mixing a dry drug and a solution. .

[0008]

As a result of diligent studies, the present inventors have found that the above-mentioned problems have been solved by a simple structure in which an opening is provided at the tip of the dissolving solution container and communication means with the vial is provided at the bottom. Have been conceived, and the present invention has been completed. That is, the present invention is a chemical solution container for use at the time of use, comprising a container body having a mouth at the tip and a hollow spike needle at the bottom, and a cap for sealing the mouth. Here, it is preferable to provide a means for engaging with the vial opening in the spike needle direction at the bottom of the container body. .

[0009]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Next, embodiments of the present invention will be described with reference to the drawings. FIG. 1 is a longitudinal sectional view of the chemical solution container of the present invention, and FIG. 2 is an explanatory diagram showing a use state of the chemical solution container shown in FIG. As shown in FIG. 1, the chemical solution container of the present invention includes a container body 1 having a mouth portion 11 at a tip end and a hollow spike needle 14 at a bottom portion 13, and a cap 3 for sealing the mouth portion 11. This is a time-solution type chemical solution container.

[0010] The container body 1 has a mouth portion (formed at a dropping port, hereinafter referred to as a dropping port) 11 at the tip, and a bottom portion 1.
3 is a cylindrical container provided with a hollow spike needle 14;
Although not shown, a dissolving solution (including a chemical solution) is contained therein. The drip port 11 is provided with a male screw 12 that is screwed with the cap 2, and is screwed with a female screw 21 of the cap 2. The spike needle 14 is at the bottom 13
When the spike needle 14 is inserted into the rubber stopper 6 of the vial V (see FIG. 2), the chemical solution container S and the vial V can be connected. A cap 3 is attached to the spike needle 14 so that the liquid medicine contained therein does not leak from the container body 1, and the cap 3 is removed at the time of use. The bottom 13 preferably has a cylindrical engagement means 1 that engages the vial opening 5 in the direction of the spike needle 14.
5 is provided at the lower end of the mouth 5 of the vial V.
A hook 151 is provided which engages with the flange 51 of the mouth 5 when it is worn on the body.

As a material for forming the container body 1 and the cap 3, a chemically resistant synthetic resin such as polyethylene or polypropylene polyester is generally employed. On the other hand, as a material for forming the cap 3, a rubber-like elastic material such as synthetic rubber such as butyl rubber, isoprene rubber, or silicone rubber, or natural rubber is preferably used. Mouth 1
1 may be formed in a drip port as shown in FIG. 1, but if necessary, for example, a rubber stopper may be provided so that an infusion set can be connected.

Next, the use of the chemical solution container S of the present invention will be described with reference to FIG. The cap 3 is removed from the spike needle 14 of the drug solution container S. At this time, the solution in the drug solution container S is introduced into the vial V, and dissolves the drug (not shown) contained therein. Is prepared. If the cap 2 is removed from the dropping port 11 of the drug solution container S in this state or in a state where the spike needle 14 is pulled out from the rubber stopper 6 of the vial V and the cap 3 is attached thereto, The drug solution can be dropped.

[0013]

As is apparent from the above description, the chemical solution container of the present invention has a simple structure, so that the manufacturing cost can be reduced and the chemical solution container can be provided at low cost. In addition, since the operation is simple, the burden on the operator is small, and no trouble is required for the mixing operation, so that there is almost no risk of contamination by bacteria.

[Brief description of the drawings]

FIG. 1 is a longitudinal sectional view of a chemical solution container of the present invention.

FIG. 2 is an explanatory diagram showing a use state of the chemical solution container shown in FIG.

[Explanation of symbols]

 S Chemical solution container 1 Container body 11 Mouth (drip port) 12 Male screw 13 Bottom 14 Spike needle 15 Engagement means 151 Hook 2 Cap 3 Cap V Vial 5 Mouth 51 Flange 6 Rubber stopper

Claims (2)

[Claims] 1. A chemical solution container for use at the time of use, comprising: a container body having a mouth at the tip and a hollow spike needle at the bottom; and a cap for sealing the mouth. 2. The chemical solution container according to claim 1, wherein means for engaging with a vial opening extending in the direction of the spike needle is provided at a bottom portion of the container body.