JPH11151310A - Proton radiation therapy device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a proton therapy device which can measure the configuration and intensity distribution of an irradiation proton ion beam (proton beam) while keeping small the amount by which the subject of examination is exposed to the beam, thus enhancing the efficiency of utilizing high-energy proton radiation. SOLUTION: This device includes: an ion source 16 producing proton ions; a proton ion quantity control means 17 for adjusting and controlling the quantity of the proton ions generated; a pre-accelerating part 18 which pre-accelerates the proton ions generated from the ion source 16; a synchrotron 21 which accelerates the pre-accelerated proton ions inside a vacuum duct serving as their passage; an irradiation system 25 which irradiates the proton ions accelerated into high energy; and a profile monitor 24 for measuring the intensity distribution of the proton ions irradiated. The quantity of proton ions is controlled by the proton ion quantity control means 17, and the subject 26 of examination is irradiated with protons as measurements are taken with the profile monitor 24.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a proton beam therapy system using a high energy proton beam, and more particularly to a proton beam therapy system for irradiating a diseased part of a subject with a high energy proton beam for treatment.

[0002]

2. Description of the Related Art X-rays, gamma rays, electron beams, and the like are used for the treatment of cancer and the like by radiation. In recent years, high-energy charged particles (ions such as hydrogen, helium, and carbon) accelerated by an accelerator. Irradiation of a beam is performed. A synchrotron is one of the methods for obtaining such high energy charged particles.

FIG. 6 shows a configuration example of a proton beam therapy apparatus for cancer or the like using a proton ion beam (proton beam) using a synchrotron. The proton beam therapy system includes an ion source 1, a pre-accelerator 2, a low energy beam transport system 3, an injector 4,
It comprises a synchrotron 5, an emitter 6, a high-energy beam transport system 7, and an irradiation system 8.

The proton ion beam is extracted by ionizing hydrogen gas by the ion source 1, preliminarily accelerated by the pre-acceleration unit 2, passes through the low energy beam transport system 3, and is incident on the synchrotron 5 by the injector 4. . The proton ions incident from the pre-acceleration unit 2 are further accelerated by the synchrotron 5 to have high energy, and when the energy reaches the energy to be used for treatment of cancer or the like, the proton ions are transported to the high energy beam transport system 7 using the emitter 6. After that, the irradiation system 8 irradiates the subject 9, which has shaped the proton ion beam into a beam shape adapted to a lesion such as cancer.

[0005] In the irradiation of a lesion of a subject 9 such as a cancer with a proton ion beam, it is required that the affected part be exposed to radiation within a short time of several minutes.

[0006]

However, whether or not the beam shape of the proton ion beam is suitable for a lesion such as cancer is determined by the profile arranged in the irradiation system 8 during irradiation of the proton ion beam. Unless the monitor 11 is used, it cannot be understood. Therefore, if the beam shape does not match the shape of the cancer lesion, or if the beam intensity is different from the expected proton ion beam intensity distribution, only a part of the affected area will be exposed to a large amount of radiation, and other affected areas will be treated. However, there is a problem that it cannot be performed sufficiently and effectively.

Further, when the beam shape does not match the shape of the lesion as described above, or the beam intensity is different from the intensity distribution of the proton ion beam, irradiation of the proton ion beam to the affected part where treatment could not be sufficiently performed is performed again. When you do
Another problem arises with increased exposure to normal tissue cells.

Therefore, when actually irradiating the affected part,
By reducing the exposure dose of the subject 9 as much as possible and measuring the shape and intensity distribution of the proton ion beam (proton beam) using the profile monitor 11, it is possible to reduce the exposure dose to the subject 9 and perform a reliable treatment. Needed to do.

[0009] In response to such a demand, irradiation is performed by reducing the amount of proton ions before treatment with proton ions,
It is necessary to measure the intensity distribution of the irradiated proton ion beam in the irradiation system 8 and then increase the amount of proton ions without changing the operation mode of the synchrotron 5 or the arrangement of the equipment in the irradiation system 8 to treat the affected part. It is.

In the accelerator using the synchrotron 5, since the proton ion beam is a pulse-like beam, the irradiation in which the pulses flying to the irradiation system 8 are thinned out using the sorting magnet 10 placed in the high energy beam transport system 7 is performed. However, even in this case, there is a problem that the amount of irradiated proton ions can be reduced by only about one digit in practical use.

Further, when the operation is performed by thinning out the pulses, a thinned proton ion beam (proton beam) is used.
Is wasted, and the problem of activation by a thinned high-energy proton ion beam occurs.

The present invention has been made in consideration of the above circumstances, and can reduce the exposure dose to the subject while measuring the intensity distribution of the irradiated proton ion beam.
It is another object of the present invention to provide a proton beam therapy system capable of improving the utilization efficiency of a high energy proton ion beam.

It is another object of the present invention to provide a proton beam therapy system which can reduce activation of equipment by high energy proton beams.

[0014]

According to a first aspect of the present invention, there is provided a proton therapy apparatus, wherein the ion generating means for generating proton ions and the amount of generated proton ions are adjusted and controlled. Proton ion amount control means, pre-stage acceleration means for pre-accelerated controlled proton ions, injection means for causing the pre-accelerated proton ions to enter a vacuum duct serving as a passage thereof, and applying the incident proton ions to the vacuum Main accelerating means for further accelerating in the duct, emitting means for emitting accelerated and high energy proton ions, measuring means for measuring the amount of emitted proton ions, and irradiating the subject with the emitted proton ions Irradiating means.

According to a second aspect of the present invention, there is provided a proton therapy apparatus, wherein the proton ion amount control means includes: a setting device for presetting the amount of proton ions; It has a controller for controlling the amount of ions.

According to a third aspect of the present invention, there is provided a proton beam therapy system, wherein the proton ion amount control means includes a lens for converging or diverging a proton ion beam emitted from the proton ion generation means. And a controller for controlling the applied voltage to the lens, and the amount of proton ions is controlled by controlling the applied voltage.

According to a fourth aspect of the present invention, there is provided a proton therapy apparatus, wherein the proton ion amount control means comprises: a deflection electrode for deflecting a proton ion beam emitted from the proton ion generation means; A deflector such as a magnet and a controller for controlling an applied voltage or an exciting current to the deflector are provided, and the amount of proton ions is controlled by the applied voltage control or the exciting current control.

According to a fifth aspect of the present invention, there is provided a proton therapy apparatus, wherein the proton ion amount control means includes: an ion source electromagnet for generating a magnetic field near an anode of the proton ion generation means; A controller for controlling the current of the ion source electromagnet, wherein the current control controls the amount of proton ions.

According to a sixth aspect of the present invention, there is provided a proton therapy apparatus, wherein the proton ion amount control means includes an applied voltage or an applied current between an anode and an extraction electrode of the proton ion generating means. Is controlled, and the amount of proton ions is controlled by the applied voltage control or the applied current control.

[0020]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The preferred embodiments of the proton beam therapy system according to the present invention will be described below with reference to the drawings.

FIG. 1 shows a first embodiment of the proton beam therapy system according to the present invention.
1 is an overall configuration diagram showing an embodiment.

This proton beam therapy device 15 is a device that can perform proton beam irradiation while adjusting and controlling the amount of proton ions.

The proton beam therapy apparatus 15 comprises an ion source 16 for generating proton ions, and a proton ion amount control means 17 for adjusting and controlling the amount of generated proton ions.
A pre-acceleration unit 18 as means for pre-accelerated controlled proton ions, a low energy beam transport system 19 for transporting pre-accelerated proton ions, and a vacuum for passing the pre-accelerated proton ions through the passage. An injector 20 as a means for entering the inside of the duct, and a synchrotron 21 as a means for accelerating the incident proton ions in the vacuum duct.
An emitter 22 for emitting accelerated and high-energy proton ions; a high-energy beam transport system 23 for transporting the emitted high-energy proton ions; and an emitted high-energy proton. It comprises a profile monitor 24 as a means for measuring ions, an irradiation system 25 as a means for irradiating the emitted high-energy proton ions, and a subject 26.

The synchrotron 21 includes a deflecting electromagnet 27
And an accelerating voltage generator 28. The deflecting electromagnet 27 confines proton ions in a vacuum duct, and the accelerating voltage device 28 accelerates the confined proton ions to increase energy.

FIG. 2 is an enlarged view showing the vicinity of the proton ion amount control means of the proton beam therapy system 15.

The ion source 16 for generating proton ions includes a duoplasmatron type ion source, a bucket (multi-cusp) type ion source, a PIG ion source, an RF ion source, and an ECR ion source. An example using a duoplasmatron ion source will be described.

The ion source 16 includes a filament 30, an intermediate electrode 31, an anode 32, an extraction electrode 33, and an electromagnet 34. An arc is discharged between the filament 30 and the anode 32 to release proton ions, while the filament 30 is An intermediate electrode 31 is inserted between the anode 32 and the intermediate electrode 31. A strong magnetic field is applied by an electromagnet 34 between the intermediate electrode 31 and the anode. The amount of proton ions emitted is increased by reducing the recombination between the ions and the plasma, and the emitted proton ions are extracted to the outside by the extraction electrode 33.

On the other hand, the proton ion amount control means 17 is provided between the ion source 16 and the pre-accelerator 18. The proton ion amount control means 17 includes a setter 35 for setting an applied voltage or current corresponding to a predetermined amount of proton ions, and a controller 36 for controlling the applied voltage or current to a preset value set by the setter 35. A lens 37 to which an applied voltage or power controlled by a controller 36 is applied;
And applies the applied voltage controlled by the controller 36 to the lens 3.
7, the proton ion beam (proton beam) emitted from the ion source 16 is converged or diverged, and the amount of proton ions passing through the slit 38 is controlled.

A high-frequency quadrupole linear accelerator is used for the pre-acceleration unit 18.
To generate a high-frequency quadrupole electric field between the four plate-like electrodes 39 and use this quadrupole electric field to focus the proton ion beam while accelerating the proton ion beam,
Irregularities are formed at the tips of the four plate-shaped electrodes 39 to create an electric field component in the traveling direction.

Next, the operation of the proton beam therapy system 15 will be described.

The proton ion beam extracted from the ion source 16 of the proton therapy device 15 is supplied to the proton ion amount control means 1.
The amount of proton ions is controlled in 7, and the controlled proton ion beam is pre-accelerated in the pre-acceleration unit 18. The pre-accelerated proton ion beam is applied to the low energy beam transport system 1
9 and the transported proton ion beam is
At 0, the light enters the synchrotron 21.

The proton ion beam incident on the synchrotron 21 is accelerated by an accelerating voltage generator 28 of the synchrotron 21 and is confined in a vacuum duct by a deflecting magnet 27. The proton ion beam accelerated and increased in energy in the vacuum duct is emitted from the emitter 22, and the emitted high energy proton ion beam is transported by the high energy beam transport system 23. The transported proton ion beam is shaped by the irradiation system 25 into a beam shape adapted to the affected part of the subject 26, and the shaped proton ion beam is measured by the profile monitor 24, and the measured proton ion beam is measured. Is irradiated on the subject 26.

Further, in the proton beam therapy system according to the present invention, the irradiation of the affected area of the subject 26 with the proton beam is divided into preliminary irradiation and main irradiation.

In the pre-irradiation, in order to make the proton ion beam extracted from the ion source 16 into an amount of proton ions suitable for the pre-irradiation, the proton ion amount control means uses an applied voltage or a voltage corresponding to a predetermined amount of proton ions. The current is set by the setting device 35, the applied voltage or current is controlled by the controller 36 to the set value set by the setting device 35, and the applied voltage or current controlled by the controller 36 is applied to the lens 37. Lens 37
By applying a controlled applied voltage or current to the lens, the lens 37 changes the focal length of the proton ion beam and increases the diameter of the proton ion beam at the slit 38, thereby causing the slit 38 of the proton ion beam to pass through. Reduce the throughput.

For this reason, in this embodiment, the intensity analysis of the irradiated proton ion beam can be measured while the exposure dose to the subject 26 is kept small, and the proton ion beam irradiated to the subject in this state can be measured. Is adjusted in the irradiation system 25.

On the other hand, in the main irradiation, in order to make the proton ion beam extracted from the ion source 16 into a proton ion amount suitable for the main irradiation, the proton ion amount control means uses a setter 35 to apply a required applied voltage or current. And the controller 36 controls the applied voltage or current to the set value set by the setting unit 35. The controller 36 controls the voltage or current applied to the lens 37. By controlling the applied voltage or current, the lens 37 changes the focal length of the proton ion beam and reduces the diameter of the proton ion beam at the slit 38, thereby increasing the amount of the proton ion beam passing through the slit.

For this reason, in the present embodiment, since the intensity distribution of the irradiated proton ion beam is measured in advance in the preliminary irradiation,
In the main irradiation, a sufficient amount of proton ion beams suitable for the subject 26 can be irradiated. In addition, waste of the energy-enhanced proton ion beam is reduced, and activation of the apparatus can be reduced.

FIG. 3 shows a second embodiment of the proton beam therapy system according to the present invention.
1 shows an embodiment, in which the vicinity of proton ion amount control means 17A is enlarged. This proton beam therapy device 1
The overall configuration of 5A is substantially the same except for the proton ion amount control means 17A, and therefore the same reference numerals are given and the description is omitted.

The proton ion amount control means 42 includes an ion source 1
6 and the pre-acceleration unit 18, and the proton ion amount control means 17A is provided with a setting unit 42 for setting an applied voltage or an exciting current corresponding to a predetermined proton ion amount.
And a controller 43 for controlling an applied voltage or an exciting current set by a setter 42, a deflector 44 connected to the controller 43, and a slit 38. An exciting current is applied to the deflector 44 to deflect the proton ion beam emitted from the ion source 16,
The amount of proton ions passing through the slit 38 is controlled. As the deflector 44, a deflection electrode or a deflection magnet is used.

Next, the operation of the proton beam therapy system 15A will be described.

In the proton beam therapy system 15A, the subject 26
Irradiation of the affected area is divided into preliminary irradiation and main irradiation.

In the preliminary irradiation, in order to make the proton ion beam extracted from the ion source 16 into a proton ion amount suitable for the preliminary irradiation, the proton ion amount control means 17A sets the required setting voltage or exciting current to the setting unit 42. And the controller 43 controls the applied voltage or the exciting current to the set value set by the setter 42. The applied voltage or exciting current controlled by the controller 43 is applied to the deflector 44.

When the applied voltage or the excitation current controlled by the controller 43 is applied by the deflector 44, the deflector 44 changes the deflection angle of the proton ion beam, shifts the center axis of the proton ion beam from the slit 38, By passing the end portion of the proton ion beam through the slit 38, the amount of the proton ion beam passing through the slit is reduced.

By reducing the amount of the proton ion beam passing through the slit, a small amount of the proton ion beam can be supplied in the preliminary irradiation, and the amount of the irradiated proton ion beam can be reduced while the amount of exposure to the subject 26 is kept small. The shape can be adjusted and the intensity distribution can be measured.

On the other hand, in the main irradiation, in order to make the proton ion beam extracted from the ion source 16 into a proton ion amount suitable for the main irradiation, the proton ion amount control means includes an applied voltage corresponding to a predetermined proton ion amount. Or set the exciting current to setter 4
The controller 43 controls the applied voltage or excitation current set in Step 2 and controls the applied voltage or excitation current applied to the deflector 44. When the applied voltage or the exciting current is controlled by the controller 43 and applied to the deflector 44, the deflector 4
Numeral 4 changes the deflection angle of the proton ion beam so that the central axis of the proton ion beam approaches the slit 38 and passes through the slit 38, thereby increasing the amount of the proton ion beam passing through the slit.

By increasing the amount of the proton ion beam passing through the slit, it is possible to supply a sufficient amount of the proton ion beam necessary for the main irradiation, and to measure the shape and intensity distribution of the irradiated proton ion beam in advance in the preliminary irradiation. Therefore, in the main irradiation, a sufficient proton ion beam suitable for the subject 26 can be irradiated. In addition, waste of the energy-enhanced proton ion beam is reduced, and activation of the apparatus can be reduced.

FIG. 4 shows a third embodiment of the proton beam therapy system according to the present invention.
It is a figure which expands and shows the vicinity. This proton beam therapy device 15
Since the overall configuration of B is the same except for the proton ion amount control means 17B, the same reference numerals are given and the description is omitted.

The proton ion amount control means 17B includes a setter 46 for setting the exciting current to a required amount, a controller 47 for controlling the exciting current to the set value set by the setter 46, and a controller 47 for controlling the exciting current. The connected electromagnet 48 and the slit 38
The excitation current controlled by the controller 47 is applied to the electromagnet 48 to change the plasma density formed in the ion source 16, the amount of proton ions extracted from the ion source 16 and the extraction from the ion source 16. The divergence angle of the generated proton ion beam is changed, and the amount of proton ions passing through the slit 38 is controlled.

Next, the operation of the proton beam therapy system 15B will be described.

In the proton beam therapy system 15B, the subject 26
Irradiation of the proton beam to the affected area is performed separately in preliminary irradiation and main irradiation.

In the preliminary irradiation, in order to make the proton ion beam extracted from the ion source 16 into a proton ion amount suitable for the preliminary irradiation, the proton ion amount control means 17B sets an exciting current corresponding to a predetermined proton ion amount. The exciting current is set to the set value set by the setting device 46 and the exciting current is controlled by the controller 47. The exciting current controlled by the controller 47 is applied to the electromagnet 48. When a controlled excitation current is applied to the electromagnet 48, the plasma density formed in the ion source 16 decreases, the amount of proton ions extracted from the ion source 16 decreases, and the amount of proton ions extracted from the ion source 16 decreases. The divergence angle of the generated proton ion beam increases, and the amount of proton ions passing through the slit 38 decreases.

By reducing the amount of proton ions extracted from the ion source 16 and reducing the amount of the proton ion beam extracted from the ion source 16 through the slit, a small amount of proton ions suitable for the preliminary irradiation is obtained in the preliminary irradiation. It is possible to adjust the shape of the irradiated proton ion beam and measure its intensity distribution with the profile monitor 24 while keeping the amount of exposure to the subject 26 small.

On the other hand, in the main irradiation, by applying an exciting current suitable for the main irradiation to the electromagnet 48, the plasma density in the ion source 16 increases, and the amount of proton ions extracted from the ion source 16 increases. At the same time, the ion source 16
The divergence angle of the proton ion beam extracted from
The amount of proton ions passing through the slit 38 increases.

By increasing the amount of proton ions extracted from the ion source 16 and increasing the amount of proton ion beam passing through the slit, it is possible to supply a sufficient and sufficient amount of proton ions for the main irradiation. In addition, since the shape and intensity distribution of the irradiated proton ion beam are measured in advance in the preliminary irradiation, a sufficient proton ion beam suitable for the subject 26 can be irradiated in the main irradiation. Therefore, extra exposure can be reduced. In addition, since there is no need to thin out the high energy proton ion beam by the distribution magnet 10, the activation of the device due to the high energy proton ion beam can be reduced.

Next, a fourth embodiment of the proton beam therapy system according to the present invention will be described with reference to FIG.

FIG. 5 is an enlarged view showing the vicinity of the proton ion amount control means 17C of the proton beam therapy system 15C used in the fourth embodiment. The overall configuration of the proton beam therapy device 15C of the present embodiment is a proton ion amount control unit 17C.
Since they are the same as those shown in the first embodiment except for, the same reference numerals are given and the description is omitted.

The proton ion amount control means 17C includes a setting unit 50 for setting an applied voltage or an applied current corresponding to a predetermined amount of proton ions, and an applied voltage or an applied current to the set value set by the setting unit 50. Controller 51 to control
, An anode 52 and an extraction electrode 53 connected to a controller 51, and a slit 38. The proton ion amount control means 17C applies the applied voltage or current controlled by the controller 51 between the anode 52 and the extraction electrode 53 to adjust and control the amount of proton ions generated by the ion source 16. The applied voltage controlled by the controller 51 applies an applied current between the anode 52 and the extraction electrode 53, changes the divergence angle of the proton ion beam extracted from the ion source 16, and changes the slit of the proton ion beam. The amount of passage is adjusted and controlled.

Next, the operation of the proton beam therapy system 15C will be described.

Also in this embodiment, the proton ion beam irradiated to the subject 26 is irradiated separately in preliminary irradiation and main irradiation.

In the preliminary irradiation, an applied voltage or an applied current corresponding to the amount of proton ions suitable for the preliminary irradiation is adjusted by the controller 51.
Is applied between the anode 52 and the extraction electrode 53. The amount of proton ions generated in the ion source 16 is reduced by changing the electric field during this period by the applied voltage or applied current. By changing the electric field, the divergence angle of the proton ion beam extracted from the ion source 16 is increased, and the amount of proton ions passing through the slit 38 is reduced.

In the main irradiation, an applied voltage or an applied current corresponding to the amount of proton ions suitable for the main irradiation is controlled by the controller 51 and applied between the anode 52 and the extraction electrode 53. The electric field between the anode 52 and the extraction electrode 53 is changed by the applied voltage or the applied current to increase the amount of proton ions generated in the ion source 16. In addition, the divergence angle of the proton ion beam extracted from the ion source 16 is reduced by this electric field, and the amount of proton ions passing through the slit 38 increases.

In this embodiment, the pre-irradiation can supply a much smaller amount of proton ions than the main irradiation. In the preliminary irradiation, the shape and the intensity distribution of the irradiated proton ion beam can be measured while keeping the amount of exposure to the subject 26 small. This irradiation can supply a sufficient amount of proton ions necessary for the treatment. In the main irradiation, since the shape and intensity distribution of the proton ion beam are measured in advance in the preliminary irradiation, the subject 26 can be irradiated with a suitable proton ion beam. In addition, magnet 1
Since the thinning of the proton ion beam with high energy by zero is not performed, the activation of the device by the proton ion beam can be reduced.

[0063]

As described above, in the proton beam therapy system according to the present invention, the shape and intensity distribution of the proton ion beam (proton beam) to be irradiated while the exposure dose to the subject is kept small. Measurement can be performed, and the utilization efficiency of the high energy proton beam can be increased.

Further, in the proton beam therapy system according to the present invention, activation of equipment by high energy proton beam can be reduced.

[Brief description of the drawings]

FIG. 1 is an overall configuration diagram showing a first embodiment of a proton beam therapy system according to the present invention.

FIG. 2 is an enlarged view showing a main part used in the first embodiment of the proton beam therapy system according to the present invention.

FIG. 3 is an enlarged view showing a main part used in a second embodiment of the proton therapy apparatus according to the present invention.

FIG. 4 is an enlarged view showing a main part used in a third embodiment of the proton therapy apparatus according to the present invention.

FIG. 5 is an enlarged view showing a main part used in a fourth embodiment of the proton therapy apparatus according to the present invention.

FIG. 6 is an overall configuration diagram showing a conventional proton beam therapy system.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Ion source 2 Pre-stage acceleration part 3 Low energy beam transport system 4 Injector 5 Synchrotron 6 Ejector 7 High energy beam transport system 8 Irradiation system 9 Subject 10 Distributing magnet 11 Profile monitor 1515A, 15B, 15C Proton beam therapy device 16 Ion source 17, 17A, 17B, 17C Proton ion amount control means 18 Pre-acceleration unit 19 Low energy beam transport system 20 Injector 21 Synchrotron 22 Ejector 23 High energy beam transport system 24 Profile monitor 25 Irradiation system 26 Subject 27 Deflection Electromagnet for use 28 Accelerator voltage generator 30 Filament 31 Intermediate electrode 32 Anode 33 Extraction electrode 34 Electromagnet 35 Setting device 36 Controller 37 Lens 38 Slit 39 Plate electrode 42 Setting device 43 Controller 44 Deflector 46 Setting device 47 Controller 48 Electromagnetic 50 setter 51 controller 52 anode 53 extraction electrode

Claims (6)

[Claims] 1. An ion generating means for generating proton ions, a proton ion amount controlling means for adjusting and controlling an amount of generated proton ions, a pre-acceleration means for pre-accelerating the controlled proton ions, and a pre-accelerated proton. Injecting means for injecting ions into a vacuum duct serving as a passage thereof, main accelerating means for further accelerating the incident proton ions in the vacuum duct, and emitting means for emitting accelerated and energized proton ions. A proton beam therapy apparatus, comprising: a measuring unit for measuring an amount of emitted proton ions; and an irradiation unit for irradiating the object with the emitted proton ions. 2. The proton beam therapy system according to claim 1, wherein the proton ion amount control means includes a setter for presetting the amount of proton ions and a controller for controlling the amount of proton ions to a set value. 3. The proton ion amount control means includes a lens for converging or diverging a proton ion beam emitted from the proton ion generation means, and a controller for controlling a voltage applied to the lens. 3. The proton beam therapy system according to claim 1, wherein the amount of proton ions is controlled. 4. The proton ion amount control means controls a deflector such as a deflection electrode or a deflection magnet for deflecting a proton ion beam emitted from the proton ion generation means, and controls a voltage or an excitation current applied to the deflector. 3. The proton beam therapy system according to claim 1, further comprising a controller, wherein the amount of proton ions is controlled by controlling the applied voltage or the exciting current. 5. The proton ion amount control means includes an ion source electromagnet for generating a magnetic field near the anode of the proton ion generation means, and a controller for controlling a current of the ion source electromagnet. 3. The proton therapy device according to claim 1, wherein the amount is controlled. 6. The proton ion amount control means includes a controller for controlling an applied voltage or an applied current between an anode and an extraction electrode of the proton ion generating means. 3. The proton therapy device according to claim 1, wherein the amount is controlled.