JPH1081336A - Glass bottle sprayed with synthetic coating material, its manufacture and manufacturing apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a bottle which can be packed with a medically active substance capable of being sprayed by an aerosol and an aerosol propellant under pressure, which has an opening capable of being closed with an administration valve, and which is coated with a synthetic material so as to protect a user from being injured by a broken bottle. SOLUTION: In order to enhance safety, a neck 2 of a bottle 1 is coated with a synthetic material in the same manner as a body thereof is coated, and a swollen edge 3 is provided at an opening of the bottle where an administration valve is mechanically mounted by turning it. A coating material 4 is comprised of an elastic synthetic material having remarkably increased shrink characteristics in order to cope with a prestress force to work on a glass main body, and, further, the bottle has like pressure relief openings 7 for releasing pressure quickly in the case where the bottle is broken.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

FIELD OF THE INVENTION The present invention relates to a glass bottle having a narrow neck which can be pressurized and filled with an aerosol sprayable substance and a propellant, the opening of which can be sealed by a discharge mechanism, and a synthetic bottle. In glass bottles sprayed with a material coating, the neck can mechanically attach the discharge mechanism, and also has a bulging edge at the opening to which the synthetic material coating is sprayed, several holes The invention relates to a glass bottle characterized in that a pressure-relieving opening in the shape of a vial is arranged in a synthetic material coating of the vial, wherein the synthetic material coating is made of an elastic synthetic material with specific high shrinkage properties and shrinks on the vial. Furthermore, the invention relates to a method for producing a spray-coated vial and to the apparatus used for carrying out the method.

[0002]

BACKGROUND OF THE INVENTION Using various coating methods and various synthetic materials,
Various types of glass containers coated with synthetic materials are well known from numerous publications. For example, German Patent No. 231,694 discloses that a solvent-free polyurethane is coated in a glass container at a predetermined thickness and / or thickness.
Or it is applied in a specific blend to have tension and flexibility.

No. 2,709,451, unpublished patent, discloses a block polymerized organic polyisocyanate having an upper outer surface, a carboxyl modification of a hydrolyzed ethyl vinyl ester copolymer and / or a hydrolyzed copolymer. Glass bottles are described that are coated with a layer of thermoset material formed from a powder containing a mixture with the article. German published application No. 2609931 describes a method in which a mixture of an elastomeric organic polymer and an organic peroxide compound is applied to the surface of a glass container, and an energy charge for the coating mixture to crosslink the polymer. charge) and methods applied in situ.

[0004] A method for applying a coating and / or encasing of a vial using high pressure is known from DE 23 33 331 A1 and DE 2 330 804 A1. This protective synthetic material coating ensures that if the coated glass container breaks, the broken glass fragments are retained together. In this way, the synthetic material coating has the effect of opposing crushing and separation. The glass container technology described above relates to beer bottles, cosmetic containers and other similar containers.

The invention is based on the specific form of the container, that is to say that it is filled under pressure, in particular with a medically active substance and a propellant, and is closed at the opening by means of a discharge mechanism, in particular a dosing valve. It relates to a pressurized container. Using a delivery head that works with the ejection mechanism, the ejection mechanism acts when both parts are pushed together and a predetermined dose of the medically active substance is ejected as an aerosol through the spray nozzle. These formulations have been used as medical applicators, especially for use in asthmatics and others suffering from bronchi. Such applicators generally consist of a pressurized container made of a metallic material. Such containers are protected from crushing and separation by using materials that are unlikely to crush (with durability and strength).

[0006] The disadvantage of these pressurized containers, however, is that due to the non-transparent material, a visual determination of the amount of substance remaining to be dispensed cannot be made. This is a real disadvantage. The reason for this is that inhalants are often used as emergency medical treatment (eg asthma medicine). If a visual determination of the contents of the container is not possible, the container may be empty if emergency treatment is needed. Pressurized containers in the form of vials are also well known. The content of the bottle is 5ml
の 間 に 50 ml. An outflow opening is attached to the upper end of the bottle. This opening usually accommodates a discharge mechanism on the pressurized container, for example a dosing valve with a cannula reaching up, usually cylindrical, which is often used with a resilient seal between the head and the dosing valve. It is closed by pressing and / or bending.

This well-known pressurized glass container is:
Except for the rim on which the dosing valve is mounted, it is coated with a transparent synthetic material that is immersed by being sprayed externally or internally. This coating consists of a flexible synthetic material with high flexibility, for example PVC. Stretching capacity is important because the increased pressure created by the crushing of the container affects the flexible synthetic material. If the flexible composite does not adapt to change in volume when subjected to pressure, abrupt failure of the flexible composite due to melting or stress corrosion will occur. This well-known pressurized container has the advantage that by using a transparent material (glass) and a transparent synthetic material coating, the amount of substance remaining in the container can be easily determined. Have.

A disadvantage of this pressurized container, on the other hand, is that it is not perfect in the event of an explosion resulting from improper handling. This means that even when coated from a synthetic material, this coating, especially in the area of the dosing valve, inflates like a balloon, preventing the fragments of the glass container from splashing into the surrounding space. This is because they cannot do it. In addition, an applicator (UK Patent Specification No. 210
No. 9333) is also well known. The applicator consists of a close-fitting shell part, ie, a glass pressurized container fitted with a protective shield, as part of its assembly. This approach has the disadvantage of high manufacturing and assembly costs. The same applies to the well-known applicator described in British Patent Specification No. 2214891, which is made of a flexible synthetic material housed in a solid synthetic shell part. It consists of a pressurized container.

[0009] The present invention now provides a process for manufacturing a final pressurized container, in which a synthetic material shattering / separation protective shield coats the glass pressurized container as an extruded thermoplastic using an injection molding apparatus. It is based on a special concept that applies. Such a concept is well known from FR-A-2 613 581. This document describes the first-mentioned vial with a narrow neck which can be filled under pressure with a substance that can be sprayed as an aerosol and with a propellant. The opening is closed by a discharge mechanism,
The bottle is sprayed with a synthetic coating.

In the best known example, a glass pressurized container consists of a bottle with a cylindrical neck, and the injection mold is such that both the neck and the opening of the bottle are sprayed with synthetic material. It is configured. However, when the bottle neck is designed in this way, problems arise in the safe placement of the discharge mechanism of the dosing valve. The coating of synthetic material covers the entire vial. If the vial breaks, the shattering / separation protection properties are lost because the coating partially bulges and bursts. In the above specification, regarding the type of synthetic material used,
It is not suggested to be important for the operation of the present invention.

[0011]

SUMMARY OF THE INVENTION The present invention is directed to a synthetic material which allows for a secure mounting of the ejection mechanism and a reduction in the strength of the vial wall while significantly increasing the shredding / separation protection properties of the container. It was developed to provide a glass pressurized container having the shape of a bottle sprayed with a coating. The solution to this problem is provided by a bottle by the following method: the neck of the bottle has a bulged edge at the opening where the synthetic coating is sprayed to facilitate the mechanical mounting of the ejection mechanism; (Bulge likeedg
e). The synthetic material coating sprayed onto the glass body is formed with several hole-shaped pressure relief openings; The coating consists of an elastic synthetic material having substantially increased shrinkage properties, and the synthetic material has shrunk onto the vial;

The bulged edge facilitates a secure and durable mechanical aspect for mounting the ejection mechanism. If the glass body breaks, the edges are also coated with a synthetic material, and the discharge mechanism remains mechanically attached because the shatter protection element is increased. The pressure relief openings prevent outward bulging of the synthetic material coating, thereby also substantially enhancing crushing / separation protection properties. If the bottle breaks, the material and propellant contained in the bottle can escape through the pressure relief holes. This escape of the contents of the vial reduces the risk of a chemical reaction between the substance contained in the bottle and the coating material (stress corrosion) and consequently reduces the risk of explosion.

In particular, the use of an elastic synthetic material having high shrinkage properties (shrinkability) surprisingly means that:
Pressure bearing capacity of sprayed glass bottles
It was found that the reload capacity was significantly higher than the pressure bearing capacity of the untreated vials. This fact makes it possible to use thinner vial walls. In this way,
Shrinkage is corrected by the elasticity of the synthetic material. The preferred synthetic material to be used is polypropylene (PP) or polyethylene (PE) or polyamide (PA).
The use of polycarbonate is also possible.

According to a further development of the bottle according to the invention, the pressure relief openings are designed in the cylindrical shell part of the bottle body close to the bottom region, of which four pressure relief openings are paired with each other. It is preferred to be placed across the This configuration allows the quickest formation of the pressure relief opening using a spring loaded centering pin of the injection mold that holds the bottle in place during the injection molding process. The glass bottles of the present invention are sold in various finishing stages. Basically shaped bottles are sold without a discharge mechanism attached. Further, the bottle can be shipped with the discharge mechanism attached in advance. Vials can be sold empty or pre-filled. However, all of these variations are still
It uses the bottle of the present invention and the benefits of protection.

The manufacturing process for obtaining the advantages of the vials according to the invention comprises the following steps:-a narrow portion with a bottom, a cylindrical shell part and a bulging edge according to conventional glass technology; The manufacture of the entire vial, including the neck, the treatment of the outer surface of the vial with the silicone oil and the final heating after it has been discharged from the cooling station on the production line, the end of the elastic synthetic material 1 with significant shrinkage properties. Spraying the entire bottle, including the rim;-forming perforated pressure relief openings in the synthetic material coating.

[0016] The surface treatment of the vial results in improved flow properties of the synthetic material in the molding die, and furthermore,
A chemical or physical reaction between the glass and the synthetic material;
Prevents freezing of the glass surface after the cooling step. The process of properly spraying the synthetic material onto the glass bottle manufactured earlier,
Centered finger-shaped devices that are adapted to the shape of the bottle and are capable of supplying extruded synthetic material and that hold the bottle in place, and moldings that form pressure relief openings This can be done using an injection molding machine in which the shell part of the bottle and a spring-loaded vertical crosspiece arranged adjacently are mounted during the process. The glass bottles according to the invention can be produced very easily using this molding device.

[0017]

BRIEF DESCRIPTION OF THE DRAWINGS Other features, advantages and uses of the invention will become apparent from the description of the embodiments shown in the drawings. FIG. 1 shows a pressurized container in the form of a vial 1 having a narrow neck 2 with a bulging edge 3 at the opening. The vial 1 could be made of, for example, borosilicate glass or lime sodium glass. The shape of this bottle is determined solely by its pressure resistance. According to the invention, the vials can be filled under pressure with sprayable, especially medically active substances, as aerosols and propellants. In this case, the bottle must be able to withstand pressures of up to 15 bar.

The glass bottle shown in FIG. 1 has a height of 54 mm and a height of 20 mm, which means that the height diameter ratio is 3.4.
Outside diameter. This ratio is preferred for bottles according to the invention. The glass bottle 1 shown in detail in FIGS. 2 and 3 is sprayed with a coating 4 made of an elastic material, preferably a transparent or opaque synthetic material having improved hardening properties and significant shrinkage. . This resilience is necessary to balance the great shrinkage. Due to the large shrinkage, the vials are subjected to a prestressing force similar to that observed in prestressed concrete, thereby surprisingly reducing the pressure resistance of the sprayed glass bottles. Many times. This fact allows the use of glass walls with relatively low strength. In the example of the present invention, a 1.5 mm thick glass wall has a coating thickness of 1 mm. The synthetic materials used for this purpose are, in particular, polypropylene (PP), polyethylene (PE) or polyamide (PA). Their shrinkage is on the order of 0.6 to 2% (% by volume).

The use of an injection molding machine to carry out the coating of the synthetic material allows for a dipping process (dippi).
The unevenness of the outer surface of the glass bottle can be completely smoothed as compared to the ng method, and the bottle shape can be replaced, for example, by filling a coating having a completely flat bottom surface. Since the stability of the glass bottle sprayed from is improved, there is an excellent advantage in that it is possible. In this case, the bottom region of the vial can also be arched outward in a semicircular shape in order to minimize the tensile stress.

The opening of the bottle has a bulging edge 3
By rotating and / or bending while inserting the seal 6, it can be closed using a mechanically mounted ejection mechanism 5. In this case, the edge of the bottle is tapered to achieve a high sealing effect. An ejection mechanism according to an example of the present invention may include a dosage valve
1ve). As can be seen from FIG. 1, the coating 4 of synthetic material also covers the bulge-like edge 3. The discharge mechanism 5 is mechanically held in place even if the glass bottle breaks, so that the safety against shattering of the glass is improved.

Several hole-shaped openings 7 are formed in the synthetic material coating 4, and two openings 7 are shown in FIG. Preferably, four such openings are arranged in pairs across each other. The pressure-releasing (or relieving) opening 7 is preferably arranged in a cylindrical shell part on the bottle body 1. This is due to the injection molding device shown in more detail in FIG. If the bottle breaks, the pressure relief opening 7 prevents the synthetic material coating from bulging. The reason for this is that the pressure inside the bottle can drop sharply as the substance and propellant contained in the bottle escape through the pressure relief opening 7. The risk of chemical action between the material contained in the bottle and the coating material due to stress corrosion is reduced, as is the risk of explosion.

The glass pressure vessel 1 is filled with the substance to be flowed alone or together with one or several propellants through the dosing valve 5. In preparation for the filling process, the glass pressurized container 1 is pressed into a cylindrical part (not shown) on which the delivery head is mounted. The delivery head easily guides the cylindrical cannula 8 of the dosing valve 5 into a similarly cylindrical, hollow receiver connected to the groove.
This groove usually terminates in an opening in the form of a spray nozzle located in the end wall of the delivery head.

A mouthpiece or a nosepiece can be attached to the delivery head. This can optionally be protected from dust by a removable cap. Such delivery heads are well known in the medical arts and, therefore, will not be described further in this regard.

FIGS. 2 and 3 show a preferred method of making the spray-coated glass bottle shown in FIG. The first manufacturing step consists in the manufacture of the whole glass bottle 1 by conventional glass technology, including the bottle bottom, the cylindrical shell part and the narrow neck to which the bulging edges are attached. Such techniques are well known and will not be shown in detail in FIG. The outer surface of the vial is sprayed with silicone oil after leaving the cooling station (Step A), after which the bottle is finally heated. This surface treatment improves the flow characteristics of the synthetic material in the mold and prevents chemical or physical reactions between the bottle and the synthetic material.

The silicone treatment of the outer surface of the vial forms an intermediate silicone layer between the vial and the synthetic coating. The synthetic material coating is so thin that, in step C, not shown in FIG. 1, the entire bottle is sprayed (spray coated) with an elastic synthetic material and a hole-shaped pressure relief opening is formed. The injection molding device used for this purpose is shown in FIG.
For further details, see Thereafter, the bottle manufacturing process includes a step D of packaging the sprayed glass bottle.
Ends with

The injection molding apparatus shown in FIG. 3 for a vial 1 including a neck 2 and an edge 3 basically consists of a knob or grip on which the vial is mounted or held in place. It comprises a tongue 9 and two blocks 10, 11 which are movable in the direction of the arrow and which have two inner surfaces 10a, 11a.
Reference numerals 0a and 11a correspond to the shape of the glass bottle, and further include a bottom portion 12 having an opening portion 13;
Is connected on the one hand to the gap 14 between the vial 1 and the surfaces 10a, 11a and on the other hand to an extruder, not shown, which serves to supply the synthetic material to be sprayed. do. Furthermore, a device showing a finger-shaped crosspiece 15 is attached to this injection molding device. The crosspiece 15 holds the vial on its center line and is located near the shell portion of the vial and serves to form a hole-shaped pressure relief opening.

The finger-shaped crosspiece 15 is in this case loaded by a spring 16 and is mechanically fixed in the block 10 in a conventional manner. FIG. 3 shows two cross pieces 15. Preferably, four such crosspieces are arranged in pairs and cross each other.

In starting the injection molding, the glass bottle 1 is pushed onto the grip 9. Then, block 10,
11 are pushed together until the block reaches the point where the gap 14 is formed. The size of the gap 14 is determined by the intended size of the coating. Eventually, the bottom 12 is displaced towards the blocks 10, 11 and the synthetic material is injected from the extruder through the holes 13 into the molding die. At that time, re-injection of the synthetic material is generally performed in order to minimize shrinkage, but in order to obtain a high level of shrinkage, in the production of the glass bottle of the present invention, so-called re-injection is performed. Is not used. After injection molding, the glass bottle 1 is removed from the injection molding apparatus in a conventional manner with the shrinked synthetic material coating 4 (FIG. 1) and placed in step D of FIG. FIG. 3 shows, of course, a particularly advantageous method,
Other injection moldings are possible.

[Brief description of the drawings]

FIG. 1 shows a glass bottle according to the invention sprayed with a 2: 1 ratio of synthetic material.

FIG. 2 is a schematic diagram of the steps involved in the manufacture of the bottle of FIG.

FIG. 3 is a detailed schematic diagram of the injection molding apparatus from FIG. 2;

[Explanation of symbols]

DESCRIPTION OF SYMBOLS 1 ... Glass bottle, 2 ... Neck, 3 ... Curved end, 4 ... Synthetic material coating, 5 ... Discharge mechanism, 6 ... Seal, 7 ... Pressure relief opening, 8 ... Cannula, 9 ... Knob, 10 ... Block, 11 ... Block, 12 ... Bottom part, 13 ... Hole, 14 ... Gap, 15 ... Cross piece, 16 ... Spring.

 ──────────────────────────────────────────────────続 き Continued on the front page (72) Inventor Joschen Heinz Germany, 55578 Bendersheim, Haoptstrasse 48 (72) Inventor Reinhard Schulter Germany, 79432 Heitersheim, Goethestrasse 9 (72) Inventor Michael Spareck, Germany 55218 Ingelheim, Am Grauenstein 12 (72) Inventor Michael Reinhard, 55270 Ober-Ol-Mum Kandstraße 1, Germany

Claims (8)

[Claims] 1. A glass bottle (1) having a narrow neck (2), which can be pressurized filled with an aerosol sprayable substance and a propellant, the opening of which is sealed by a discharge mechanism (5). Possible and in a glass bottle to which a synthetic material coating (4) is sprayed;-a neck (2) to which a discharge mechanism (5) can be mechanically attached and a bulge to which the synthetic material coating is sprayed; Having an edge (3) in the opening; several hole-shaped pressure relief openings (7) being arranged in the synthetic material coating (4) of the vial (1); A) a glass bottle characterized in that it is made of an elastic synthetic material having a specific high shrinkage property and shrinks on the glass bottle. 2. A synthetic material such as polypropylene (P
2. A glass bottle according to claim 1, wherein P) or polyethylene (PE) or polyamide (PA) is used. 3. The method according to claim 1, wherein the pressure relief opening is formed in the cylindrical shell part of the coating on the vial near the bottom region. The glass bottle as described. 4. The glass bottle according to claim 3, wherein the four pressure relief openings (7) are arranged in pairs across each other. 5. The method according to claim 1, wherein a silicone layer is obtained between the outer surface of the vial (1) and the synthetic material coating (4), which is obtained by spraying the surface of the vial with silicone. The glass bottle according to any one of claims 1 to 4. 6. A method for producing a glass bottle according to claim 1, comprising the following process: The bottom, the cylindrical shell part and the bulging edge are attached by conventional glass technology. Producing an entire vial having a narrow neck, which has a narrow neck,-treating the outer surface of the vial with silicone oil after the cooling station on the production line, followed by final heating;-the entire bottle including the edges Spraying an elastic synthetic material having a particular strong shrinkage property,-forming a hole-shaped pressure relief opening in the area where the synthetic material coating has been sprayed. 7. An injection molding apparatus (9,10,11,12) adapted to the shape of a bottle capable of supplying synthetic material by extrusion, holding the bottle in a central position and injecting. A spring-loaded finger-like crosspiece (15, 16) disposed adjacent to the shell part of the bottle body (1) and forming a pressure relief opening (7)
7. Apparatus for performing the method according to claim 6, wherein the synthetic material coating is sprayed onto a pre-manufactured glass bottle, characterized in that it comprises a forming device having 8. Device according to claim 7, characterized in that four crosspieces (15, 16) are provided, the crosspieces being arranged in pairs across each other.