JPH10118096A - Fitting tool for fixing plate for bone prosthesis material and fixing plate for bone prosthesis material - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a fitting tool which is suitable for fitting a fixing plate for a bone prosthesis material with a plurality of holes for fitting contg. holes for fitting to an autobone to a bone prosthesis material with a through-hole penetrating to the inner and outer faces among the bone prosthesis materials used for prosthesis of a bone defect part of maxillofacial bones of cranial bones. SOLUTION: A flange 4 for hooking is provided on the back end face of a fitting tool main body 2 in such a way that it can be inserted into a through- hole K from the inner face side and it is not projected from the outer face side. A screw hole 6 whose axial line is vertical to the back end face is provided on the apex face 5. This fitting tool 1 is inserted into the through-hole K of a bone prostheeis material C from the apex face 5 and a fixing plate 21 is applied on the outer face side and a screw member 23 is screwed into a screw hole 6 from a hole 22 for fitting to adjust it so as to position the hole 22 for fitting to an autobone Z at an appropriate position and a bottom hole is opened in the bone prosthesis material C and the screw member 23 is screwed therein. The bone prosthesis material C is strongly fixed thereby into the autobone Z.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention cuts and removes a part (autologous bone) of a craniofacial bone (hereinafter, also simply referred to as a skull) when a part of the bone is affected by a bone tumor or the like. Among the bone replacement materials used for later bone defect replacement (surgery), those having an appropriate number of through-holes penetrating the inner and outer surfaces are provided with a plurality of mounting holes, including holes for autogenous bones. The present invention relates to a fixture used to mount a provided bone replacement material fixing plate, and a bone replacement material fixing plate (hereinafter, also simply referred to as a fixing plate).

[0002]

2. Description of the Related Art When a skull is cranulated by neurosurgery or the like, a bone fragment (autogenous bone) cut after the operation is covered, and the skull is fixed to surrounding autogenous bone (natural bone). Therefore, the plate can be fixed firmly firmly by screwing it on with a tapping screw (self-tapping screw) or driving a nail with a retaining projection called a haken, so that the plate can be straddled from the outside. Also, due to a bone tumor or the like, a part of the skull is cut, even when the bone defect after the removal is replaced with a bone replacement material, when the bone replacement material is made of plastic,
Since the processing is easy, it can be fixed in the same manner as described above.

[0003] By the way, such a bone substitute is made of ceramic, which is particularly preferable in terms of its biocompatibility and bonding with living bone, and is a preferable material. However, ceramic bone fillers can be processed to the extent of drilling due to their properties, but it is difficult to make a screw on itself, so they cannot be fixed as described above. Was fixed in this way.

[0004] That is, when performing an operation of filling a bone defect with a ceramic bone replacement material, a ceramic bone replacement material having the same shape and size as the bone defect portion is formed.
As shown in FIG. 10, an appropriate number of through holes Ka (about 10 places along the outer peripheral edge depending on the size of the bone prosthesis, etc.) are drilled in the outer peripheral edge of the bone replacement material C with a drill. Open.
Then, a similar through-hole Kb is obliquely formed in the inner peripheral edge of the bone defect of the patient's skull (autogenous bone) Z so as to correspond to the through-hole Ka, and the bone replacement material C is replaced with the bone defect. Then, the nylon thread N is passed through the through holes Ka and Kb of each other to be sewn and fixed. The reason why the through hole Kb of the autogenous bone is an inclined hole is to prevent the dura or the like from being damaged when the autogenous bone is bored or during the suturing process.

[0005]

In such an operation, it is required to shorten the operation time and to make the recovery after the operation as quick as possible.
However, the fixation by suturing with a nylon thread requires a lot of operation time due to the necessity of making a large number of inclined holes Kb in the autogenous bone Z and a large amount of labor for suturing, which makes it difficult to shorten the operation. was there. In particular, when drilling a hole in an autogenous bone, it is difficult to machine the hole, and it is necessary to carefully perform the drilling, so that it takes a considerable amount of time only to drill the hole.

Further, in order to accelerate post-operative recovery, it is necessary to connect the new bone (bone tissue) and the bone replacement material in the vicinity of the replacement site at an early stage. It must be firmly and stably fixed to the autologous bone (living bone) Z. However, fixation by suturing with a nylon thread does not provide a satisfactory and sufficient fixation strength, which causes a long period of time for postoperative recovery. Further, in some cases, it may cause false joints due to poor bone tissue connection, which is presumed to be caused by insufficient fixation with the living bone.

Accordingly, the present invention provides a bone filling material having an appropriate number of through-holes penetrating through the inner and outer surfaces of a bone filling material used for filling a bone defect in a craniofacial bone, and a hole for attachment to an autogenous bone. Provided is a mounting device suitable for mounting a bone replacement material fixing plate having a plurality of mounting holes, including the above, so that the bone replacement material can be firmly fixed to autologous bone via the fixing plate in a relatively short time. It is an object of the present invention to provide a fixing plate suitable for the above.

[0008]

In order to achieve the above object, a fixture for a bone replacement material fixing plate according to the first aspect of the present invention is used for filling a bone defect in a craniofacial bone. Used to attach a bone replacement material fixing plate having a plurality of attachment holes including a hole for attachment to an autogenous bone to a bone replacement material having an appropriate number of through holes penetrating the inner and outer surfaces thereof. An attachment, formed in the through-hole of the bone prosthesis so as to be insertable from the inner surface side of the bone prosthesis, and the through-hole on the outer periphery of a rear end surface of the bone prosthesis so as not to protrude from the outer surface of the bone prosthesis. A locking portion that can be locked is projected
In addition, a screw hole is formed in the front end surface with its axis substantially perpendicular to the rear end surface.

In the mounting device according to the first aspect of the present invention, a number of through holes for the bone prosthesis are prepared and inserted into the through holes of the bone prosthesis from the respective distal end surfaces thereof. (Microplate) is applied, screw holes such as screws are screwed into the screw holes so that the mounting holes correspond to the screw holes on the distal end surface, and the holes for mounting the bone replacement material fixing plate to the autogenous bone are at appropriate positions. Adjust so that After that, if necessary, tighten the screw member, and then set the screw in the bone defect, apply each fixing plate to the surface of the autogenous bone, and prepare a pilot hole in the autogenous bone corresponding to the mounting hole. The bone filling material is fixed by drilling and screwing a screw member into the autogenous bone from the mounting hole.

[0010] The bone filling material is adjusted in advance so as to fit the bone defect, and has a proper number of through holes penetrating into appropriate places on both the inner and outer surfaces. Although depending on the size of the bone filling material, generally, it is provided at about four or more places, and preferably at equal angular (distance) intervals, and a fixing plate is attached to each of the places using the fixture according to the present invention.

[0011] As described above, when the bone substitute is fixed via the fixing plate using the fixture according to the present invention, the machining of the autogenous bone is performed by forming a prepared hole for screwing the screw member into the bone surface. It is only necessary to open it substantially perpendicularly, and mounting (fixing) is by screwing a screw member. Therefore, the operation time can be shortened as compared with the case of suturing with a nylon thread, and the attachment of the bone replacement material to the autogenous bone is also performed by tightening the screws, so that the attachment strength can be improved.

[0012] In order to achieve the above object, according to the second aspect of the present invention, there is provided a mounting device for a bone replacement material fixing plate, which comprises a bone replacement material used for repairing a bone defect in a craniofacial bone. To those with an appropriate number of through holes penetrating the inner and outer surfaces,
What is claimed is: 1. A fixture used for attaching a bone filling material fixing plate having a plurality of attachment holes including an attachment hole to an autogenous bone, comprising: a base plate and at least two projections standing on one main surface thereof. Portion, the convex portion is formed in a through hole of the bone replacement material so as to be insertable from the inner surface side of the bone replacement material, and is formed at a height that does not protrude from the outer surface side of the bone replacement material. A screw hole is formed in the tip end surface of the projection so that its axis is substantially perpendicular to one main surface of the substrate.

[0013] In the mounting device according to the second aspect, the convex portion is inserted into the through hole of the bone prosthesis from the inner surface side, and a plurality of mounting holes including the mounting hole for the autogenous bone are formed on the outer surface side. A similar well-known bone replacement material fixing plate as before is applied, and a screw member such as a screw is screwed in such that its mounting hole corresponds to the screw hole on the distal end surface of the projection. Then, similarly to the attachment according to the first aspect, the fixing plate can be similarly fixed to the bone replacement material by adjusting the mounting hole of the bone replacement material fixing plate to the autogenous bone to be at an appropriate position, Thereafter, it may be fixed to the autogenous bone in the same manner. In this means, since there are two or more projections, when screwing into the screw holes, the other parts have a detent function, so that the fastening reliability is high. It is preferable that both of the attachments according to the first and second aspects are made of a biocompatible metal such as titanium or a titanium alloy.

In the fixture according to the second or third aspect, the following fixing plate may be used in place of the known fixing plate. That is, a bone replacement material fixing plate provided with a plurality of mounting holes including holes for mounting to autogenous bones in an arrangement corresponding to the screw holes of the protrusions of the mounting tool of the bone replacement material fixing plate, When the protrusion of the fixture for the bone replacement material fixing plate is inserted into each through hole of the bone replacement material and the substrate is applied to one surface of the bone replacement material, the curved surface state of that surface of the bone replacement material A screw member can be screwed into each of the screw holes by allowing the variation of the interval between the screw holes on the tip end surface of the convex portion caused by the above, so that an appropriate number of the mounting holes are formed into elongated holes. It is characterized by having done.

The distance between the screw holes on the distal end surface of the projection of the fixture is such that the projection of the fixture is inserted into each through-hole of the bone replacement material, and the substrate is placed on one surface of the bone replacement material. When the bone filling material is broken, it slightly changes depending on the curved surface state of the surface. That is, when the substrate is applied to the surface of the bone filling material, the smaller the radius of curvature of the curved surface state, the larger the distance between the protruding portions on the distal end surface side than on the proximal end surface side (substrate side). Therefore, in such a case, there may be a problem that the screw member cannot be inserted in the fixing plate having the circular mounting holes. However, the fixing plate according to the fourth aspect of the present invention allows the screw member to be screwed into each of the screw holes of the protruding portion while allowing a change in the interval between the screw holes generated at this time. Is formed in the elongated hole, which is effective in avoiding such a problem. In addition, it is preferable that this bone replacement material fixing plate is also made of a biocompatible metal such as titanium or a titanium alloy.

[0016]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Next, an embodiment of a mounting device according to the present invention will be described in detail with reference to FIGS. However, C in the figure is a ceramic bone filling material such as an apatite sintered body to be filled in a bone defect part (affected part) of a patient's skull (hereinafter also referred to as autogenous bone) Z, and is substantially equivalent to the bone defect part. It is formed in a slightly spherical shape like the original autogenous bone so that it can be set without a gap, and although not shown in detail, the appropriate place (for example, four places)
A circular through-hole K having a predetermined diameter is formed through the inner and outer surfaces.

1 and 2, reference numeral 1 denotes a fixture of the present embodiment. The fixture 1 is a fitting body 2 made of a pure titanium cylindrical body, and is provided on an outer periphery of a lower end surface 3 of the fitting body 2 so as to be able to be locked in a through hole K. The locking flange 4 is formed of a circular thin plate integrally and concentrically protruding as a stopper. However, the outer diameter of the main body 2 is about 3 mm in this example, and the outer diameter of the locking flange 4 is about 6 mm in this example. In the center of the upper end surface 5 of the main body 2, a screw hole (M1.4 in this example) 6 having a predetermined depth in the axial direction of the cylindrical body is formed. Note that the outer diameter of the main body 2 is slightly smaller than the through hole K provided in the bone replacement material C, and the height thereof is the depth of the through hole K of the bone replacement material C, that is, the height of the bone replacement material C. It is set smaller than the thickness. The main body 2 has a lower end surface 3 having a circular boss 7.
The engagement flange 4 is formed by crimping the boundary M of the fitting. However, the main body 2 and the locking flange 4 may be manufactured integrally.

The fixture 1 of the present embodiment is similarly used in each through-hole K, but is as follows. First, as shown in FIGS. 1 and 2, the main body 2 is fitted into the through-hole K of the bone replacement material C from the inside from the distal end face 5 side. Then, the mounting hole 22 of the known fixing plate 21 is aligned with the screw hole 6 of the mounting tool 1 in consideration of mounting on the autogenous bone Z, and a screw member 23 made of pure titanium or the like is screwed (temporarily tightened). The bone replacement material C is sandwiched between the locking flange 4 and the fixing plate 21. This allows
The fixing plate 21 is firmly fixed to the bone replacement material C. The known fixing plate 21 shown in the figure is made of a thin plate having a substantially constant width, is formed in a straight state, and is attached to the surface of the autogenous bone Z at a position near one end (upper right in FIG. 1). In this embodiment, two mounting holes (in this case, inner diameter of about 1.3 mm) 22b into which members can be inserted are provided.

In this state, the hole in this state is set in the bone defect portion, and a lower hole of the screw member 23 is formed in the fixing plate 21 at the position of the hole 22b for attachment to the autogenous bone Z substantially perpendicular to the bone surface. When the screw member 23 is screwed into the surface of the autogenous bone Z through the mounting hole 22b and fixed, the bone replacement material C is firmly fixed to the autogenous bone Z via the fixing plate 21. The height of the main body 2 above the locking flange 4 is
Bone-reinforcing material (human craniofacial bone) C to be replaced in the bone defect
Depending on the thickness (3 to 8 mm), it may be smaller and have an appropriate height.

In this embodiment, the screw holes 6 provided in the main body 2 are provided.
Is formed in the form of a blind nut whose back end (tip) is closed, so that a screw member 2
Even if 3 is used, it is formed so as not to damage the dura or the like at its tip. In the above, the main body 2 of the fixture 1
And the locking flange 4 is formed in a disk shape. However, the present invention is not limited to this, and the main body 2 is formed into a prism such as a square pole as in the fixture 1 shown in FIG. 4
May be a disk shape (or a square plate shape). The main body 2 is formed in a prismatic shape, and a through hole having a similar cross-sectional shape is formed in the bone filling material, so that when the screw member is screwed into the screw hole 6 of the main body 2 at the time of attaching the fixing plate, the idle rotation occurs. Danger is gone. In addition, even when the screw hole is provided eccentrically from the center of the circle, the danger of idling can be reduced. In addition, the main body may have an elliptical column shape whose upper end surface shape and cross-sectional shape are elliptical.
As in the case of the attachment 1 shown in FIG. 1, the main body 2 may be formed in a columnar shape in which the shape of the upper end surface 5 and the cross-sectional shape form a split circle in which a part of a circle is cut. By drilling a through-hole having a similar cross-sectional shape in the bone replacement material even in such a case, there is no danger of idling when the screw member is screwed into the screw hole of the main body when the fixing plate is attached.

Further, as in the case of the fixture 1 shown in FIG. 5, the upper end face 5 of the main body 2 is formed in a corrugated shape in the form of a crown gear, and the lower surface around the mounting hole of the fixing plate is fixed. Even if it is formed in irregularities so as to fit into the irregularities, idling can be prevented. In the above description, one fixture is used for one fixture.
Although the case where the fixing plate is used has been described, a T-shaped fixing plate 31 as shown in FIG. , 6 may be screwed into each, and fixed to the autologous bone through another mounting hole 22b.

Next, an embodiment embodying the present invention described in claim 3 will be described in detail with reference to FIGS. However, description of portions common to the previous example will be omitted as appropriate. 7 and 8, reference numeral 41 denotes a fixture of this embodiment, which is a substrate 42 made of a strip-shaped titanium thin plate.
And cylindrical projections 43, 43 erected on both ends thereof. The substrate 42 is formed in a substantially strip shape so that it can be easily bent (plastically deformed) with a fingertip or a surgical plier (in this example, a length of about 23 mm and a width of about 8 m).
m, the thickness is about 0.5 mm), and both end portions 44, 44 are formed to protrude in an arc shape in plan view as shown in FIGS. The radius of the circular arc of the end portion 44 of the substrate 42 is set to be large enough to be engaged with the peripheral surface Ks of the opening of the through hole K of the bone replacement material C.

On the other hand, a screw hole (M1.4 in this example) 46 having a predetermined depth is formed in the center of the upper end surface 45 of the projection 43. However, the axis of the screw hole 46 is perpendicular to the main surface of the substrate 42, and the outer diameter of the convex portion 43 is smaller than the inner diameter of the through hole K provided in the bone replacement material C. The height is set smaller than the depth of the through hole K of the bone replacement material C, that is, the thickness (3 to 10 mm) of the bone replacement material. In this example, the convex portion 43 is also made of titanium, and a circular boss 47 is formed on the lower end surface thereof so as to protrude downward.
Is fitted in a circular hole 48 provided at the center of the radius of the arc of the both ends 44, 44 of the substrate 42, and is fixed by caulking the boundary M thereof.

Thus, through holes K, K are drilled at a predetermined pitch in the bone replacement material C to be repaired in the bone defect, and the projection 43 of the fixture 41 in this embodiment is connected to one surface of the bone replacement material C. (FIG. 8 lower surface) is inserted into each through-hole K from the side. Then, if necessary, the substrate 42 is bent by pressing it against the lower surface (contact surface) of the bone replacement material C. Then, from the other surface (the upper surface in FIG. 8) of the bone replacement material C, the respective convex portions 43, 4
3, a conventionally known, for example, a T-shaped bone replacement material fixing plate (see FIG. 6) 31 having a plurality of mounting holes including a mounting hole 22 b for autogenous bone Z is applied to the screw member 23, 23 through the mounting hole 22 and the screw hole 4
Screw into 6. Thus, the fixing plate 31 is firmly fixed to the bone replacement material C, and thereafter, may be used for surgery in the same manner as described above. In addition, the mounting tool 41 of the present example is
Since there are two places, there is no idling when the screw member 23 is screwed in, so that it is securely tightened.

As shown in FIG. 9, one of the fixing holes of the fixing plate 31 used in FIGS. 7 and 8 is a circular hole 52 and one of the fixing holes is fixed to the projection 43, and the other is both mounting holes. The following effects can be obtained by using one formed in the long hole 53 having a long diameter in the direction connecting the use holes. That is, depending on the curved surface state (radius R) of the bone replacement material C, the interval between the screw holes 46, 46 of the convex portions 43, 43 of the fixture 41 is closer to the proximal end side (substrate surface side) on the distal end surface 45 side. Although it is larger than the interval, if the slot is formed in this way, the screw member can be screwed in while allowing or absorbing the difference. As described above, the fixation plate allows the screw member to be inserted into the screw hole by allowing a change (increase) in the interval between the screw holes on the distal end surface of the protrusion generated due to the curved surface state of the bone filling material. In this case, it is preferable that an appropriate number of the mounting holes are formed in the elongated holes. The longitudinal direction of the long hole may be set according to the arrangement and number of the mounting holes so as to allow a change in the interval between the screw holes and allow the screw member to be inserted into the screw hole.

As a matter of course, the projection 4 of the fixture 41
In the case where the distance between the screw holes 46, 46 is substantially the same as the distance on the distal end surface 45 side on the base end side (substrate surface side), and there is no need to absorb the difference, the mounting holes It is sufficient to use fixing plates of various shapes such as a conventionally known T-shape in a plan view such as a circular shape or a linear shape for each of the convex portions.

The height of the projection 43 may be appropriately designed to be smaller than the thickness of the bone filling material C within a range not exceeding the thickness according to the thickness of the bone replacement material C. In addition, the protrusion 43 is not limited to the column shape. Naturally convex part 4
The space between the 3, 43 may be appropriately designed so that it can be inserted into each through hole K.

Further, the planar shape and size of the mounting plate or the number and position of the projections may be appropriately set according to the bone defect in the craniofacial bone, the bone filling material and the through hole therethrough. Good. That is, although not shown, the planar shape of the mounting device according to claim 2 can be embodied as various shapes such as an L shape, a T shape, and an H shape, and an appropriate flat (planar) shape such as a square or a triangle. It can also be. Of course, in any case, the convex portion provided with the screw hole may be formed not only at the end (or corner) or the end (or corner) of each portion, but also at an appropriate position such as the middle. Good.

The material of the fixture and the fixing plate is made of titanium or a titanium alloy, which has biocompatibility, high strength, corrosion resistance,
It can be said that the material is more preferable, such as non-toxicity and easy bending workability. However, the present invention is not limited to this. However, the mounting board and fixing plate depend on the shape and material, but are as thin as possible as long as the strength is secured.
And it is preferable to make it easy to bend by plastic deformation. Further, in this example, the case has been described in which the bone replacement material C is apatite having an excellent bondability with new bone, but any material may be used as long as it has biocompatibility and sufficient strength and is suitable as a replacement material. Can be used. That is, the same can be applied to a plastic or metal bone substitute.

[0030]

According to the attachment for the bone filling material fixing plate according to the first aspect of the present invention, the bone filling material having an appropriate number of through-holes penetrating through the inner and outer surfaces of the bone filling material has an autogenous bone. It is possible to firmly attach a bone replacement material fixing plate having a plurality of attachment holes including a hole for attachment to a bone. Accordingly, thereafter, the screw member is screwed into the autogenous bone through the attachment hole for the autogenous bone of the fixing plate, whereby the bone replacement material can be firmly fixed to the autogenous bone in a relatively short time.

According to the attachment of the bone replacement material fixing plate of the second aspect of the present invention, in addition to the effect of the attachment of the first aspect, at the time of attachment, there are two or more projections. At the time of screwing into the screw hole, the other members perform a detent function, and the reliability of tightening is high.

According to the bone filling material fixing plate of the fourth aspect of the present invention, even if the interval between the screw holes on the distal end surface of the projection of the mounting tool varies depending on the curved surface state of the bone filling material, the plate for mounting is not required. Since the holes are elongated, the holes can be fixed while allowing their fluctuation.

[Brief description of the drawings]

FIG. 1 is a perspective view of an embodiment of an attachment according to claim 1, and an exploded perspective view of a state in which a bone replacement material fixing plate is fixed to the bone replacement material using the attachment.

FIG. 2 is a partially broken sectional view showing a state in which a bone replacement material fixing plate is fixed to the bone replacement material using the fixture of FIG. 1;

FIG. 3 is a perspective view of another example of the fixture of FIG. 1;

FIG. 4 is a perspective view of another example of the fixture of FIG. 1;

FIG. 5 is a perspective view of another example of the fixture of FIG. 1;

FIG. 6 is an exploded perspective view showing a state in which one bone replacement material fixing plate is fixed to the bone replacement material using the two attachments of FIG. 1;

FIG. 7 is a perspective view of an embodiment of the attachment according to claim 2, and a perspective view for explaining a state in which a bone replacement material fixing plate is fixed to the bone replacement material using the attachment.

FIG. 8 is a partially broken cross-sectional view showing a state where the bone replacement material fixing plate is fixed to the bone replacement material using the fixture of FIG. 7;

FIG. 9 is a perspective view of an embodiment of the bone replacement material fixing plate according to claim 4.

FIG. 10 is a partial cross-sectional view illustrating fixing of a conventional ceramic bone replacement material.

[Explanation of symbols]

 1, 41 Mounting device for bone replacement material fixing plate 2 Mounting device main body 3 Rear end surface 4 Locking flange (locking portion) 5 Tip surface 6, 46 Screw holes 21, 31 Bone replacement material fixing plate 22, 22b, 52 For mounting Hole 23 Screw member 42 Substrate 43 Convex portion 45 Tip surface of convex portion 53 Long hole C Bone filling material K Through hole Z Autogenous bone

Claims (5)

[Claims] 1. A bone substitute material having a proper number of through-holes penetrating the inner and outer surfaces of a bone filling material used for filling a bone defect portion of a craniofacial bone, including a hole for attachment to an autogenous bone. An attachment used for attaching a bone filling material fixing plate provided with a mounting hole for the bone filling material, wherein the bone filling material is formed so as to be insertable into the through hole of the bone filling material from the inner surface side of the bone filling material, A locking portion that can be locked to the through hole is protrudingly provided on the outer periphery of the rear end surface so as not to protrude from the outer surface side of the filling material,
In addition, a screw hole is formed in the distal end surface so that its axis is substantially perpendicular to the rear end surface. 2. A bone substitute material having a proper number of through-holes penetrating the inner and outer surfaces of a bone filling material used for filling a bone defect portion of a craniofacial bone, including a hole for attaching to an autogenous bone. A mounting tool used for mounting a bone replacement material fixing plate provided with a mounting hole of (1), comprising a substrate and at least two protrusions erected on one main surface thereof, wherein the protrusions are A screw hole is formed in the through hole of the bone prosthesis so as to be insertable from the inner surface side of the bone prosthesis material and at a height that does not protrude from the outer surface side of the bone prosthesis material. An attachment for a bone replacement material fixing plate, the axis of which is formed substantially perpendicular to one main surface of the substrate. 3. The attachment for a bone replacement material fixing plate according to claim 1, wherein the attachment is made of a biocompatible metal such as titanium or a titanium alloy. 4. A bone provided with a plurality of mounting holes, including holes for mounting on autogenous bone, in an arrangement corresponding to the screw holes of the projections of the mounting device of the bone replacement material fixing plate according to claim 2 or 3. A bone filling material fixing plate, wherein a projection of a fixture of the bone filling material fixing plate is inserted into each through hole of the bone filling material, and the substrate is applied to one surface of the bone filling material. A screw member can be screwed into each of the screw holes by allowing a change in the interval between the screw holes on the distal end surface of the convex portion caused by the curved surface state of the surface of the filler material. A bone filling material fixing plate, characterized in that a number of the holes are formed in elongated holes. 5. The bone replacement material fixing plate according to claim 4, wherein the plate is made of a biocompatible metal such as titanium or a titanium alloy.