JPH09286719A - Adhesion preventing agent composition for condom and condom coated with the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject composition excellent in preventing effects on adhesion between films of a condom, by using a specific compound. SOLUTION: This composition comprises one or more of an etherified substance or an esterified substance of a polyoxyethylene such as a polyoxyethylene oleyl ether and an esterified substance of a polyoxyethylene sorbitan such as a polyoxyethylene sorbitan monooleate, having inhibitory effects on adhesion and nonionic surface activity. A condom coated with the composition is extremely excellent in long-term storage stability.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a condom used for the purpose of contraception and the prevention of infectious diseases such as sexually transmitted diseases. The present invention provides a composition and a condom coated with the composition.

[0002] Compared with a condom in which a powder or granular material such as silica, which is typical as a conventional anti-adhesive agent for condoms, is applied to the condom film, the condom film between the condom films during long-term storage of the rolled-up condom is increased. , Which greatly improves the effect of preventing sticking, and more specifically, improves wearability due to its excellent anti-adhesion effect, and further improves the lubricity of the condom film to improve texture and use. It improves the feeling. In addition, the anti-adhesion effect can be further improved by using it together with any conventionally known condom-preventing agent for condoms.

When a known arbitrary oily and / or water-soluble wetting agent is applied to a condom coated with the anti-adhesive composition for condom of the present invention, the anti-adhesive composition of the present invention is obtained. The above wetting agent shows extremely excellent compatibility, and the wetting agent penetrates into the condom film to greatly improve the texture and feel during use.

[0004]

2. Description of the Related Art Conventionally, most anti-adhesives for condoms are mainly composed of powdery or granular materials. For example, mineral materials such as talc, silica and mica, and seeds and spores such as Ishimatsuko and corn starch. Attempts have been made to use plant materials, polyolefins such as polyethylene and polypropylene, synthetic resin materials such as polystyrene, polymethylmethacrylate, polyvinylacetate, and other plastic granules, and compositions in which they are mixed in a condom film. Came (actual fair 6-1,700).

[0005]

However, none of these anti-adhesive agents are satisfactory in anti-adhesion effect, and it is time-consuming to attach the condom films due to adhesion of the condom coatings, or adhesion of a plurality of particulates to each other during use. The anti-adhesion effect is weakened due to such factors as inadequate, and the problem of adhesion between condom films remains for long-term storage etc., and in the case where distorted particles adhere to the condom film, There are also problems such as impairing the texture at the time of use and worsening the feeling of use due to increased frictional resistance, there are drawbacks such as lowering the condom's commercial value rather than causing an excessive cost increase,
No conventional anti-adhesive has been found that can be satisfactorily used for this purpose.

[0006]

Therefore, in order to solve such problems, the present inventors reduce, improve or remove the adhesive force between condom films and the friction resistance between condom and skin / mucous membrane. We have carefully studied the materials to be added and used for the purpose, and above all, it is highly safe chemically and biologically, does not change the material when temperature and humidity change, and can be stored for a long time. Also, the composition of the anti-adhesive agent which did not decompose or deteriorate was examined.

[0007] In the case where the anti-adhesive composition of the present invention is constituted by using in combination any known powdery or granular component having an anti-adhesive effect when applied to a condom, for example, talc, silica and mica. Synthetic resin materials such as mineral materials such as, etc., plant materials such as seeds and spores such as Ishimatsuko and corn starch, polyolefins such as polyethylene and polypropylene, plastic granules such as polystyrene, polymethyl methacrylate and polyvinyl acetate, etc. There is no deterioration such as dissolution, swelling, softening, deterioration or coloring due to long-term contact with, etc., and it can withstand sustained attack by microorganisms such as mold and bacteria well, and is also satisfactory in terms of biological safety. It is a thing.

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION The anti-adhesive composition of the present invention uses, as a main component, an etherified product, an esterified product of polyoxyethylene or an esterified product of polyoxyethylenesorbitan described in "Claim 1". These materials show excellent anti-adhesion effects on condoms when used alone or in combination of two or more of them, but various known minerals having anti-adhesion effects on condoms. It is needless to say that the material, the plant material or the synthetic resin material can be used in combination to take advantage of the synergistic effect of the combined use of these liquid, powdery or granular anti-adhesive agents, and can be obtained by carrying out the present invention. Various known oil-based and / or water-soluble wetting agents may be applied to the condom before use.

The polyoxyethylene etherification product which can be used as the main component of the anti-adhesive agent of the present invention includes polyoxyethylene lauryl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether and polyoxyethylene oleyl ether. , Polyoxyethylene palmityl ether, polyoxyethylene tridecyl ether, polyoxyethylene dodecyl ether, and esterification products of polyoxyethylene include polyoxyethylene monolaurate, polyoxyethylene monooleate, polyoxyethylene monodecyl ether. Stearate, polyoxyethylene monopalmitate,
There are polyoxyethylene monolinoleate and polyoxyethylene monosebacate, and as esterification products of polyoxyethylene sorbitan, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan monostearate, and polyoxyethylene sorbitan monostearate Oxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monolinoleate, polyoxyethylene sorbitan dilaurate, polyoxyethylene sorbitan dioleate, polyoxyethylene sorbitan distearate, polyoxyethylene sorbitan dipalmitate, polyoxyethylene sorbitan dilinoleate , Polyoxyethylene sorbitan trilaurate, polyoxyethylene sorbitan trioleate, polyoxyethylene sol Sorbitan tristearate, sorbitan monooleate tripalmitate, polyoxyethylene sorbitan tanto Lili methanolate.

Known anti-adhesive agents for condoms that can be used in combination with the anti-adhesive agent of the present invention include talc, silica,
Mineral materials such as mica, plant materials such as stone seeds and corn starch, plant materials such as spores, polyolefins such as polyethylene and polypropylene, polystyrene, synthetic resins such as polystyrene, polymethylmethacrylate and polyvinylacetate There is material.

All of these materials are originally used by being added to cosmetic materials, food materials, medical devices, etc., and are the etherification products, esterification products or polyoxyethylene sorbitan of the polyoxyethylene of the present invention. The biological safety of the anti-adhesive composition for condoms of the present invention containing an esterified product as a main component is high. In the anti-adhesive composition of the present invention having such a constitution, various modifiers are further added while maintaining the safety and functionality of the composition,
It is also possible to improve the added value of the composition for use, and as such a modifier which can be added to the composition of the present invention with such a purpose, various synthetic and natural product-derived coloring agents are used. , Fragrances, flavors, surfactants, preservatives, vitamins, anti-bacterial agents, antibacterial agents, deodorants, anti-inflammatory agents, various spermicides, contraceptives, hormones, etc. It is possible to select and use one kind or two or more kinds.

The polyoxyethylene etherification product, esterification product, or polyoxyethylene sorbitan esterification product used in "Claim 1" is relatively stable against acids and alkalis because it has no ionicity. Can be used in a wide pH range, ether type and ester type are acid,
It has a relatively good resistance to alkali, and generally can be used in combination with other ionic surfactants. The polyoxyethylene etherification product, esterification product, or polyoxyethylene sorbitan esterification product used for this purpose can use water, oils, or alcohols as a solvent.

That is, the polyoxyethylene chain in the etherified product, esterified product of polyoxyethylene, or esterified product of polyoxyethylene sorbitan is generally too hydrophobic when it is completely removed. Since the solubility or dispersibility of the binder composition in the solvent or dispersion medium becomes too low, it may cause troubles in operation, and the use effect becomes too small, and the chain length of the polyoxyethylene chain may be reduced. On the other hand, when the length is longer than 50 mer, the hydrophilicity is generally too strong and the operability and the use effect are too low. Therefore, the etherified product of the anti-adhesive composition used in the present invention is generally used. The chain length of the polyoxyethylene chain of the esterified product, the esterified product, or the sorbitan esterified product must be 1 to 50 mer of oxyethylene. The chain length of the polyoxyethylene chain to be used by adjusting to approximately 1 to 50, anti-adhesive composition of the suits liquid to the usage and purpose of using these are characterized by obtained.

[0014] A polyoxyethylene etherified product, esterified product or polyoxyethylene sorbitan esterified product according to claim 1 and a known powdery or granular component having an anti-adhesion effect as an anti-adhesive agent for condoms. When used as an anti-adhesive composition by mixing with, a known arbitrary material that can be used together as one component of the anti-adhesive composition for condom is used as an etherified product, esterified product, or polyoxylated product of polyoxyethylene. It can be dissolved, dispersed, or mixed in an esterified product of ethylene sorbitan to be applied to a condom film as a uniform anti-adhesive composition for condom.

[0015]

A natural or synthetic condom made by applying the anti-adhesive composition of the present invention prevents adhesion between condom films and causes physical and chemical deterioration even during long-term storage. It is possible to maintain biological safety without doing so. Further, various polyoxyethylene etherified products according to the "claim 1" of the present invention,
When only the esterified product or the esterified product of polyoxyethylene sorbitan is applied to the condom film as the anti-adhesive composition, the anti-adhesion effect is exhibited without any particles on the surface of the condom film, and the film is extremely smooth. Therefore, the texture and the feeling during use can be characterized.

[0016]

The present invention will be described in more detail with reference to the following examples.

[0017]

Example 1 A condom made by uniformly coating both sides of a natural rubber latex condom with an oleyl etherified methoxide of a 20-mer ethylene glycol was prepared and evaluated, and the results are shown. The results are shown in Table 1.

[0018]

[Example 2] Stearyl ether of methoxyoligoethylene glycol used in "Example 1" and fine powder silica having an average particle size of 9 µm, which has been used as an anti-adhesive agent in the past, were used in a ratio of 10: 1 (weight ratio, the same below. ), The anti-adhesive composition prepared by mixing in), a condom made by uniformly coating both sides of a natural rubber latex condom, and evaluated.
The results are shown in Table 1.

[0019]

[Example 3] Polyoxyethylene oleyl ether used in "Example 1" and a viscosity of 100 m at 25 ° C.
A condom formed by uniformly coating both sides of a natural rubber latex condom with an anti-adhesive composition composed of a 1: 1 mixture of m ² / s silicone oil (polydimethylsiloxane type) was prepared and evaluated. Is shown in Table 1.

[0020]

Example 4 An anti-adhesive composition comprising a 5: 2 mixture of a compound obtained by cetyl etherification of a 10-mer polyethylene glycol monomethoxy compound and glycerin was uniformly applied to both sides of a natural rubber latex condom. A condom formed by applying to the above was prepared and evaluated, and the results are shown in Table 1.

[0021]

On both sides of Example 5 condom was produced in the same manner as "Example 1", the strawberry odor synthetic fragrances with 0.3% to 500 mm 2 / ^s of silicone oil (polydimethylsiloxane), a mixture obtained by dissolving The resulting condom was evaluated by uniformly spraying it on both sides of a natural rubber latex condom, and the results are shown in Table 1.

[0022]

Example 6 An anti-adhesive composition comprising a 10: 1 mixture of stearic acid ester of monomethoxypolyethylene glycol and polymethylmethacrylate beads having an average particle size of 10 μm used in “Example 4” was applied to a polyurethane condom. A trial condom formed by uniformly coating both surfaces was evaluated, and the results are shown in Table 1.

[0023]

[Comparative Example 1] A condom was prepared by uniformly coating both sides of a natural rubber latex condom with a fine powder synthetic silica having an average particle diameter of 9 µm as an anti-adhesive agent, and evaluated. The results are shown in Table 1. .

[0024]

Comparative Example 2 An anti-adhesive composition comprising a 5: 100 mixture of the anti-adhesive silica used in "Comparative Example 1" and a silicone oil (polydimethylsiloxane-based) having a viscosity of 500 mm ² / s at 25 ° C. A condom formed by uniformly coating both sides of a natural rubber latex condom was prepared and evaluated, and the results are shown in Table 1.

[0025]

Comparative Example 3 An anti-adhesive composition comprising a 1:10 mixture of the anti-adhesive silica and glycerin used in "Comparative Example 1" was prepared.
A condom made by applying it uniformly on both sides of a natural rubber latex condom was created and evaluated, and the results are shown in Table 1.
It was shown to.

Table 1 summarizes the evaluation results of the long-term storability, wearability and feeling of use of the condoms prepared in the above Examples and Comparative Examples.

[0027]

As described above in detail with reference to Examples and Comparative Examples, an oily silicone oil, a water-soluble polyethylene glycol, glycerin, and an anti-adhesive which have been conventionally used as a wetting agent for condoms. Condoms to which silica etc. are adhered have a problem in that their adhesiveness, texture during use, and feeling during use are impaired, resulting in unsatisfactory wearability during use and feeling during use, reducing the value of the product. It was

However, the anti-adhesive composition of the present invention, which is mainly composed of an etherified product, an esterified product of polyoxyethylene, or an esterified product of polyoxyethylene sorbitan, is used as an anti-adhesive for condoms. , It has excellent features such as shape, safety, heat resistance, transparency, chemical and biological stability, and it is clear that it has the effect of preventing adhesion between condom films. It was At the time of use, it improves wearability due to its excellent anti-adhesion effect, and improves the texture and feeling due to the smoothness of the condom film, and also in combination with various known powdery or granular anti-adhesive agents. By doing so, it is possible to further improve the anti-adhesion effect, and it can be said that the present invention is a truly significant invention.

Claims (4)

[Claims] 1. Polyoxyethylene lauryl ether, polyoxyethylene cetyl ether, polyoxy among polyoxyethylene etherified products, esterified products or polyoxyethylene sorbitan esterified products having nonionic surface activity having anti-adhesion effect. Ethylene stearyl ether, polyoxyethylene oleyl ether, polyoxyethylene palmityl ether, polyoxyethylene tridecyl ether, polyoxyethylene dodecyl ether, polyoxyethylene monolaurate, polyoxyethylene monooleate, polyoxyethylene monostearate, Polyoxyethylene monopalmitate, polyoxyethylene monolinoleate, polyoxyethylene monoabacate, polyoxyethylene sorbitan monolaurate, polyoxy Sorbitan monooleate, polyoxyethylene sorbitan monostearate,
Polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monolinoleate, polyoxyethylene sorbitan dilaurate, polyoxyethylene sorbitan dioleate, polyoxyethylene sorbitan distearate, polyoxyethylene sorbitan dipalmitate, polyoxyethylene sorbitan dirytate Nolate, polyoxyethylene sorbitan trilaurate, polyoxyethylene sorbitan trioleate, polyoxyethylene sorbitan tristearate, polyoxyethylene sorbitan tripalmitate, polyoxyethylene sorbitan trilinoleate, one kind selected from the group or An anti-adhesive composition for a condom, which comprises two or more kinds, and a condom coated with the composition. 2. A known adhesion preventive agent for condoms, which has an effect of preventing adhesion to a condom film and the etherified product, esterified product or polyoxyethylene sorbitan of polyoxyethylene of claim 1. Is,
Mineral materials such as talc, silica and / or mica, plant materials such as stone seeds and / or corn starch, plant materials such as spores, polyolefins such as polyethylene and polypropylene, polystyrene, polymethylmethacrylate and / or polyacetic acid An anti-adhesive composition for a condom, which is formed by using a synthetic resin material such as a granular plastic material such as vinyl, and a condom coated with the composition. 3. A known condom such as an oily silicone oil or water-soluble glycerin for the film of a condom coated with the anti-adhesive composition for a condom according to claim 1 or 2. A condom coated with a wetting agent. 4. A surfactant, a lubricant, a pigment, a flavoring agent, for a condom film obtained by carrying out the invention described in "Claim 1", "Claim 2" and "Claim 3". Any ingredients such as fragrances, deodorants, vitamins, hormones, preservatives, antifungal agents, antibacterial agents, bactericides, spermicides, contraceptives and antiphlogistics, known foods, pharmaceuticals and cosmetic materials The applied condom.