JPH09240727A - Lid material sheet for ptp - Google Patents

Abstract

PROBLEM TO BE SOLVED: To make the disposal after use simple and keep from increasing the waste by introducing a sheet with a specified thickness and a specific bursting strength which consists of polypropylene, polyethylene, their copolymer, or one of their mixtures and inorganic filler used against specific parts by weight of the resin. SOLUTION: As regards a resin A consisting of polypropylene, polyethylene, their copolymer, or one of their mixtures polypropylene homopolymer, ethylene- propylene copolymer, etc., may be referred to as examples. A sheet as the product should have a thickness of 0.01-1mm and a bursting strength of 0.01-5kg/cm<2> . To provide the sheet with a good push-through property an inorganic filler, consisting of talc, mica, alumina, etc., is indispensable and for this purpose it is important for the quantity of the addition of such an inorganic filler to be 5-150 pts.wt. based on 100 pts.wt. of the resin A. This constitution provides the lidding material with a good push-through property and enables simplifying the recycling after use and the disposal of the material as waste.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to pharmaceuticals such as tablets and capsules,
The present invention also relates to a cover material sheet for a press-through package (hereinafter referred to as PTP) used for packaging foods and the like.

[0002]

2. Description of the Related Art Conventionally, for packaging medicines, foods, etc., an aluminum foil lid material coated with an adhesive is used as a bottom material by storing the contents in a pocket part formed by molding a plastic sheet into a pocket shape. A so-called PTP, which is a package obtained by adhering a flat portion other than the pocket portion of the bottom material by heating or the like, is used. PTP is widely used as an extremely convenient packaging mode in which the contents are taken out by breaking through the aluminum foil lid material by pushing the pocket-shaped portion of the bottom material with a finger. However, in the conventional PTP, since the lid material is completely different from the aluminum foil (inorganic material) and the bottom material is plastic (organic material), the separation processing is necessary, and the recycling or incineration processing after use is very difficult. Therefore, it has been desired to change the lid material from aluminum foil to plastic.
Ordinary plastic sheets were too strong as a lid material and lacked push-through properties during use (removal of contents). Push-through property here means filling the contents such as tablets into the bottom material molded into a pocket shape,
It indicates the easiness of tearing of the lid material when taking out the contents after adhering to the lid material.

[0003]

The object of the present invention is to replace the conventional aluminum foil (inorganic material) with the PTP lid material by simplifying the treatment such as recycling after use and disposal by incineration. Provide a lid material that suppresses the generation of dust.

[0004]

The present invention has a thickness of 0.01.
~ 1mm sheet, polypropylene, polyethylene,
According to JIS P8112, 5 to 150 parts by weight of an inorganic filler is added to 100 parts by weight of a resin composed of ethylene / propylene rubber or a copolymer or mixture thereof.
The rupture strength of the Murren low pressure test is 0.01-
PT with push-through property of 5.0 kg / cm ²
A lidding sheet for P, wherein the inorganic filler is at least one component selected from talc, kaolin, mica, alumina, wollastonite, and clay.

The polypropylene, polyethylene of the present invention,
Examples of the resin composed of ethylene propylene rubber or a copolymer thereof (hereinafter referred to as resin (A)) include, for example,
Polypropylene homopolymer, ethylene-propylene copolymer, low density polyethylene (LDPE), medium density polyethylene (MDPE), high density polyethylene (HDP)
E), linear low-density polyethylene, and ethylene / propylene rubbers include a rubbery copolymer of ethylene and propylene (EPM), EPM and EPD having an unsaturated group in the side chain.
M, etc. may be mentioned, and a mixture thereof may be used. The thickness of the sheet is 0.01 to 1 mm,
If it is thinner than 0.01 mm, the strength is weak, and if it is thicker than 1 mm, the push-through property is deteriorated. The push-through property can be evaluated by measuring the burst strength by a Murren low pressure tester based on JIS P8112, and the burst strength must be 0.01 to 5.0 kg / cm ² by this method. When less than 0.01 kg / cm ² is not suitable for practical use too brittle, as large as the opening (when taken out of the content) when using the hardly push-through than 5.0 kg / cm ^2, is practically unsuitable.

An inorganic filler is necessary to give the push-through property of the present invention. Examples of the inorganic filler include talc, mica, alumina, wollastonite, kaolin, clay, and the like, but talc, kaolin, mica, alumina, wollastonite are suitable from the viewpoint of practical hygiene, and talc and kaolin are more suitable. .
Talc is a filler represented by the chemical composition formula 4SiO ₂ · 3MgO · H ₂ O, and kaolin is a chemical composition formula 2SiO ₂ · Al.
It is a filler represented by ₂ O ₃ · 2H ₂ O. The addition amount of the inorganic filler is important for imparting the push-through property, and the addition amount of the inorganic filler is 5 with respect to 100 parts by weight of the resin (A).
˜150 parts by weight, preferably 10 to 120 parts by weight. If the amount is less than 5 parts by weight, the push-through property is not imparted to the lid material sheet, and if the amount is more than 150 parts by weight, it becomes too brittle to be formed into a sheet.

The sheet forming method of the present invention is not particularly limited, and examples thereof include an extrusion method, a calendar method, a hot platen press method and the like. In addition to the resin (A) and the inorganic filler, additives or other resins may be added and copolymerized to the extent that the desired physical properties such as push-through properties are not impaired. Examples of the additives include stabilizers, processing aids, antioxidants, ultraviolet absorbers, pigments, etc., and other resins include, for example, ethylene / α-olefin copolymer, propylene / α-olefin copolymer, ethylene.・ Α-olefin / diene copolymer, propylene / α-olefin
Diene copolymer, ethylene / vinyl acetate copolymer, ethylene / (meth) acrylic acid copolymer, ethylene / ethyl acrylate copolymer, propylene / (meth) acrylic acid copolymer, ethylene / maleic anhydride Copolymer, polystyrene, styrene / acrylonitrile copolymer, styrene (meth) acrylic acid copolymer, styrene / butadiene copolymer, styrene / butadiene / styrene copolymer (SBS), hydrogenated styrene / butadiene / styrene copolymer Examples thereof include polymers (SEBS), isoprene rubber, butadiene rubber and the like.

[0008]

EXAMPLES Examples will be shown below, but the present invention is not limited to these examples. A lid material sheet was prepared by a hot melt extrusion method using the formulations of the resin (A) and the inorganic filler shown in Tables 1 and 2. A commercially available polypropylene (homopolymer, MI = 1.6 g / 10 min., 230 ° C.) with a thickness of 0.3 mm is used for the bottom sheet, and a plug-pneumatic PTP molding machine (FBP-M2, manufactured by CKD). ) To load the contents (tablets) and PTP
I got The evaluation results of these PTPs are shown in Tables 1 and 2. The PTP molding conditions and evaluation method are as follows. PTP molding conditions: bottom material pocket molding temperature 180 ° C., seal temperature 160 ° C., machine speed 6.3 m / min.・ Breath strength measurement: Using the Murren burst degree tester (manufactured by Toyo Seiki Co., Ltd.) based on JIS P8112 ・ Push-through property: Practical evaluation of taking out contents (tablets) from PTP

Resin (A);-PP: polypropylene Nobrene H-501, Sumitomo Chemical Co., Ltd.-PE1: low density polyethylene Sumikasen L-21.
1. Sumitomo Chemical Co., Ltd. ・ PE2: High density polyethylene HIZEX 3300
F, Mitsui Petrochemical Co., Ltd.-PE3: α-olefin linear low-density polyethylene-PE4: EVA (ethylene-vinyl acetate copolymer) Ultracene UE630 Toyo Soda Co., Ltd.-PP-EPM: Polypropylene elastomer T-31
0J, Tokuyama Corp.-EPM: ethylene / propylene rubber copolymer EP07
P, Japan Synthetic Rubber Co., Ltd.-EPDM: Ethylene-propylenediene rubber EP5
7P, Nippon Synthetic Rubber Co., Ltd. inorganic filler; -Talc: MS-A, Nippon Talc Co., Ltd.-Kaolin: ASP-200, Hayashi Kasei Co., Ltd.-Mica: FM-H01, Hayashi Kasei Co., Ltd.-Walrus Knight: VM-8N, Hayashi Kasei Co., Ltd.-Clay: Kaolin clay # 10, Hayashi Kasei Co., Ltd.

[0010]

[Table 1]

[0011]

[Table 2]

[0012]

According to the present invention, the PTP bottom material and the lid material are the same material, and the lid material has push-through properties, and the recycling and disposal after use is simple and useful for environmental protection.
A P lid sheet is obtained.

[Brief description of drawings]

FIG. 1 is a sectional view of a PTP obtained by the present invention.

[Explanation of symbols]

 1 Bottom material pocket portion 2 Bottom material flat surface portion 3 Lid material 4 Contents (tablets)

Claims (2)

[Claims] 1. A sheet having a thickness of 0.01 to 1 mm, comprising 5 to 150 parts by weight of an inorganic filler with respect to 100 parts by weight of a resin made of polypropylene, polyethylene, ethylene / propylene rubber, or a copolymer or mixture thereof. The PTP lid material sheet has a burst strength of 0.01 to 5.0 kg / cm ² according to the Murren low pressure test of JIS P8112. 2. The PT according to claim 1, wherein the inorganic filler comprises at least one of talc, kaolin, mica, alumina, wollastonite and clay.
Cover material sheet for P.