JPH09235490A - Antibacterial coated article - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an antibacterial coated article with persistent antibacterial properties by coating an article with an antibacterial coating compsn. contg. an antibacterial agent comprising a cyclodextrin compd. and hiba oil, a binder resin, and a solvent. SOLUTION: An antibacterial agent having a particle size distribution ranging from 0.5μm to 150μm and a max. particle size of 3-15μm is prepd. by mixing 99-60wt.% at least one cyclodextrin compd. selected from among α-cyclodextrin, maltosyl-β-cyclodextrin, dimaltosyl-α-cyclodextrin, etc., with 1-40wt.% hiba oil. The agent is mixed with specified amts. of a binder resin selected from among shellac, methyl cellulose, and rosin and an ethyl alcohol-propylene glycol mixture as the solvent to give an antibacterial coating compsn. contg. 1-40wt.% antibacterial agent. The compsn. is applied to paper, films, nonwoven fabrics, etc., to give antibacterial coated articles.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to an antibacterial coated product produced by applying an antibacterial coating agent containing an antibacterial agent consisting of a mixture of cyclodextrins and hiba oil using a coating method. It is a thing.

[0002]

2. Description of the Related Art Conventionally, sheet-like products obtained by impregnating or spraying hinokitiol extracted from Aomori Hiba oil diluted or dissolved in a solvent have been used for the purpose of antibacterial and freshness preservation. It was

However, these products have the following problems, and their improvement has been desired.

(1) The duration of the antibacterial effect is short.

Since the above-mentioned hinokitiol is a sublimable substance, it is highly volatile in an environment other than a normal state or a closed state, and its effect is short-lived.

(2) It is easily removed by water or other liquids.

Even hinokitiol or its inclusion with cyclodextrins, which is diluted or mixed with water or solvent and impregnated or sprayed on the product, may cause rain, dew drops, etc. during use. When exposed to liquids such as water, fruit juice, and body fluids, the above-mentioned hinokitiol drops off and the effect is lost.

(3) It is difficult to set conditions for the coating amount of the antibacterial agent.

Considering to control the amount of hinokitiol, which is the main component of antibacterial, by the amount of adhesion per unit area, it is impossible to arbitrarily set strict conditions. It is possible to adjust the content of hinokitiol in the coating agent, but if the method of adhesion is impregnation, spraying, or the like, the level of control will be roughly after all. Also,
Considering the volatility of hinokitiol, it is difficult to control the coating amount of the antibacterial component.

(4) It cannot be applied to arbitrary parts and shapes.

[0011] In the conventional method of impregnation or spraying, it is often difficult to apply the antibacterial agent to a desired portion, area (size), shape and pattern in terms of cost and reproducibility. In addition, the method of impregnation limits the applicable material of the product.

There is also a sheet-shaped product in which hinokitiol, which is an antibacterial component, is directly kneaded into a resin, but such a sheet-shaped product obtained by kneading an antibacterial agent has a drawback that the amount of the antibacterial agent used is large and the cost is high. is there. That is, in the method by kneading, since the antibacterial agent is uniformly dispersed in the entire resin, it is not possible to increase the ratio of the antibacterial agent to the surface layer exhibiting the effect. It is necessary to increase the total amount of the antibacterial agent used, resulting in high cost.

[0013]

SUMMARY OF THE INVENTION The present invention has been made in view of the above-mentioned problems of the prior art. The object of the present invention is to eliminate the disadvantages of conventional impregnation, spraying or kneading, and to provide cyclodextrins. An object of the present invention is to provide a coated product having antibacterial properties, which is manufactured by applying an antibacterial coating agent containing an antibacterial agent composed of a mixture of citrus oil and hiba oil using a coating method.

[0014]

In order to solve the above-mentioned problems, the invention of claim 1 coats with an antibacterial coating agent containing an antibacterial agent consisting of a mixture of cyclodextrins and hiba oil, a binder resin and a solvent. A coated product having antibacterial properties, characterized by being obtained by coating using a method.

The invention according to claim 2 is the coated product having antibacterial properties according to claim 1, characterized in that the coated product is a sheet-shaped product such as paper, film, and non-woven fabric.

The invention according to claim 3 is the coated product having antibacterial properties according to claim 1 or 2, wherein the coating is performed by a printing method.

The invention according to claim 4 is the coated product having antibacterial properties according to claim 1, 2 or 3, wherein the binder resin is shellac, zein, methylcellulose or rosin.

The invention of claim 5 is characterized in that the solvent is a mixed solvent of ethyl alcohol and propylene glycol or a mixed solvent of them and water. A coated product having the described antibacterial properties.

Further, in the invention of claim 6, the mixing ratio of the cyclodextrins and the hiba oil is 99% to 60%: 1.
% -40%, Claims 1, 2, 3,
A coated product having antibacterial properties as described in 4 or 5.

Further, in the invention of claim 7, the particle size distribution of the mixture of the cyclodextrin and the hiba oil is 0.5 μm.
m-150 μm, and the maximum distribution is 3 μm
It is in the range of 15 μm.
A coated product having antibacterial properties according to 3, 4, 5 or 6.

[0021] The invention of claim 8 is such that the content of the mixture of the cyclodextrin and the hiba oil is 1% by weight to.
40% by weight, claim 1, 2, 3,
A coated product having antibacterial properties according to 4, 5, 6 or 7.

[0022]

Embodiments of the present invention will be described below in detail.

The antibacterial agent used in the present invention comprises a mixture of cyclodextrins and Hiba oil as described above. The Hiba oil used in the present invention is an essential oil of Hiba (Hinaceae) and has an antibacterial action. Have. Hiba oil is obtained, for example, by steam-distilling sawdust from the trunk of Hiba. The main component of this Hiba oil is Tsuyopsen (C ₁₅ H ₂₄ ) which is a neutral oil component which is one of the sesquiterpene hydrocarbons, and is also a scent component which is said to have a soaking effect on the forest. In addition, albeit in a small amount, α-tsuyapurisin and γ
-Tsuyapricin (3- and 5-isopropyltropolone) and, to a small extent, β-tsuyaprisin (4-isopropyltropolone, ie, hinokitiol), and β-drabulin, carvacrol, rosin acid, and other antibacterial and antifungal activities. It also contains highly acidic oil components.
In addition, hinokitiol (β-tsuyaprisin) has already been commercialized for applications such as medical care and freshness maintenance. However, when used as hiba oil due to the synergistic effect of the above-mentioned many components in hiba oil, salmonella bacteria, It has also been confirmed that hinokitiol has an effect on black aspergillus and the like that is not exhibited by hinokitiol. Hiba oil is also referred to as “Aomori Hiba oil” because it is mainly produced in Aomori Prefecture.

In the above cyclodextrins used in the present invention, 6 units or more of glucose are α-1,4.
It is a linked cyclic oligosaccharide, and specific examples include, for example,
Maltosyl α-Cyclodextrin, Maltosyl β
-Cyclodextrin, dimaltosyl α-cyclodextrin, dimaltosyl β-cyclodextrin, α-cyclodextrin and the like are exemplified, but in the present invention, 1 of these cyclodextrins is used.
A single type may be used alone, or a plurality of types may be mixed and used.

The antibacterial agent to be used in the present invention can be obtained by mixing the above cyclodextrins with hiba oil, and the mixing method may be any conventionally known means. The obtained mixture is a state in which Hiba oil is included in cyclodextrin.

In the antibacterial agent used in the present invention, it is important to set the mixing ratio of cyclodextrin and hiba oil in such a range that a sufficient antibacterial action can be obtained. If the amount is too small, a sufficient antibacterial action cannot be obtained, and conversely, if the mixture ratio of Hiba oil is too large, in terms of the antibacterial action, there is no particular inconvenience, but the cost is high, which is not preferable. In the antibacterial agent used in the present invention, the mixing ratio of cyclodextrin and hiba oil is 9
9% -60%: in the range of 1% -40%, especially 90% -75
%: A mixing ratio in the range of 10% to 25% is desirable.

In the antibacterial agent used in the present invention, the particle size of the mixture of cyclodextrin and hiba oil is not particularly limited. However, the smaller the particle size, the larger the surface area. 0.5 μm to 150 μm
m, and the maximum of the distribution is preferably in the range of 3 μm to 15 μm, and particularly the particle size distribution is 2 μm to 20
It is preferably in the range of μm.

Since the antibacterial agent used in the present invention is so safe that it can be orally administered to the human body, the coated product of the present invention can be used in applications such as food packaging materials and medical hygiene materials. . The antibacterial agent used in the present invention is also effective against non-contact bacteria such as various bacteria in the atmosphere,
In addition to the antibacterial effect, it also has the effect of relieving psychological stress, so it will be possible to commercialize products that can expect their synergistic effects.

As described above, the antibacterial agent used in the present invention is a state in which the hiba oil is included in cyclodextrin, and therefore, the antibacterial effect is sustained and the antibacterial action of the hiba oil is long-lasting. .

The antibacterial agent used in the present invention is a mixture of cyclodextrins and hiba oil. Hiba oil is clathrated by cyclodextrin and has a sustained-release effect, which has a long-lasting antibacterial effect. Instead of mixing Hiba oil with cyclodextrins as described above, a method in which Hiba oil is microencapsulated with an appropriate resin is also conceivable. However, in the case of microencapsulation, the content is released only when it is destroyed by being subjected to heat, pressure, etc., and there is no sustained release like an inclusion compound, and the cost is high. Inappropriate for some reason. In that respect, the antibacterial agent used in the present invention is safe and has a sustained release property, and since the Hiba oil is 1/50 of the price of the hinokitiol simple substance, it can be produced at a low cost.

The antibacterial coating agent used in the present invention is
It contains a mixture of the above-mentioned cyclodextrins and hiba oil as an antibacterial agent.

The mixing ratio of the cyclodextrin of the antibacterial agent used in the antibacterial coating agent used in the present invention and the hiba oil and the particle size of the mixture are preferably within the above range.

The antibacterial coating agent used in the present invention is
In addition to the antibacterial agent, it contains a binder resin and a solvent as components necessary for coating.

As the binder resin in this case, an acrylic resin, a urethane resin or the like, which is generally used as a binder for paints, can be optionally used. Especially when the coated product of the present invention is used for food packaging and the like. The use of resins such as shellac is preferred. Shellac is a natural resin obtained by refining the secretions of Lactophyllidae (insects belonging to the family Hymenoptera) and is a substance approved under the Food Sanitation Law. In addition to shellac, it is also preferable to use resins such as zein, methyl cellulose, and rosin.

As the above-mentioned solvent, any solvent generally used in paints can be optionally used.
For example, solvents such as ethyl alcohol and propylene glycol are approved as food additives under the Food Sanitation Law, so when these solvents are used, the coated product of the present invention can be used for food packaging applications and the like. Becomes
It is also possible to use a mixed solvent of the above solvent and water.

Incidentally, the coating agent may appropriately contain appropriate additives.

In the antibacterial coating agent used in the present invention, the content of the above-mentioned antibacterial agent is not particularly limited, but if the content of the antibacterial agent is too small, a sufficient antibacterial action cannot be obtained, and conversely. If the content of the antibacterial agent is too large, the cost is high even if there is no particular inconvenience in terms of antibacterial action, and it is not preferable. A content within the range is desirable.

The coated product of the present invention is obtained by applying the above antibacterial coating agent using a coating method.

In the present invention, the coating method is preferably a printing method.
In the coating by the printing method, it is possible to strictly set the condition of the coating thickness, and it is possible to finely control the coating amount of the antibacterial agent. In addition, the coating by the printing method has a high degree of freedom in a coatable portion, a shape, and the like, has high mass productivity, and has good reproducibility. The printing method in this case includes, for example, a gravure printing method and a screen printing method.

The coated product of the present invention can be applied to products for various purposes. Depending on whether the coated product of the present invention is a final product or a raw material before the final product is processed into the final product. However, for example, when used as a sheet-shaped product such as paper, various films, and non-woven fabrics,
Since it can be widely used as a material for various products,
It is particularly suitable.

Specific application examples (or use examples) of the coated product of the present invention are as follows.

(1) Food packaging material The coated product of the present invention is an orally available material such as a binder resin and a solvent such as shellac resin and ethyl alcohol, in addition to the antibacterial agent consisting of a mixture of cyclodextrins and hiba oil. By using
For the purpose of antibacterial, antifungal, freshness preservation, etc., it can be used as a highly safe packaging material that can directly package food.

(2) Household goods The coated product of the present invention is used for packaging clothing, futons, etc.
It can be used as a product for the purpose of protecting insects, mites, molds, etc. that protect the objects to be packaged by processing them into packaging materials for packaging and other household sundries.

(3) Bedding Since the antibacterial main ingredient, Hiba oil, used in the present invention has an effect of relieving psychological stress in addition to the antibacterial effect as described above, the coated product of the present invention. Suppressing the generation of microorganisms by processing sheets into sheets, pillow covers, etc.
It can be used as bedding that is safe and clean, and has high functionality that enhances the effect of sleeping.

(4) Freshness-maintaining material Since the antibacterial main component, Hiba oil, used in the present invention has a cell-activating effect and a freshness-retaining function in addition to the antibacterial effect, it is mainly used for agricultural products such as fruits and vegetables and cut flowers. It can be used as a freshness keeping sheet for fresh foods.

(5) Medical material By processing the coated product of the present invention into a sheet, a pillow cover, a bandage, etc., use as a medical material for the purpose of medical effects such as alleviation of symptoms of atopic dermatitis. Is possible.

(6) Building Material The coated product of the present invention can be applied to antibacterial and antibacterial properties by processing it into a decorative sheet such as interior wallpaper or ceiling material.
It can be used as a building material for the purpose of preventing mold and ticks.

As described above, since the coated product of the present invention is coated with a binder resin of an antibacterial agent having a sustained release property in which hiba oil is clathrated with cyclodextrins, it has an antibacterial effect. It is possible to extend the duration significantly.

Further, in the coated product of the present invention, since the antibacterial agent is attached to the surface of the article to be coated by the action of the binder resin, the antibacterial agent does not easily drop off even when exposed to water or other liquids. Has become.

Further, in the coated product of the present invention, since the coating film containing the antibacterial agent is formed by using the coating method, it is possible to finely set the coating amount of the antibacterial agent. For example, by setting conditions such as the mixing ratio of Hiba oil and cyclodextrins in the antibacterial agent, the antibacterial agent in the coating agent, the mixing ratio of the binder resin and the solvent, and the coating thickness of the coating agent, the antibacterial agent or this The application amount of the antibacterial component contained in can be finely controlled. In particular, when coating is performed by a printing method, it is possible to set strict conditions for the coating amount of the coating agent.

Further, since the coated product of the present invention is coated by using a printing method or the like, there is a large degree of freedom in selection of applicable objects, parts, shapes, etc., and the desired coated product can be manufactured at low cost. , Can be obtained with good reproducibility.

Furthermore, since the coated product of the present invention has a thin coating containing an antibacterial agent applied to the surface of the article to be coated, it is equivalent to the conventional method of kneading the antibacterial agent into a resin. The amount of the antibacterial agent required to obtain the effect of is small, which is a great advantage in terms of cost.

[0053]

EXAMPLES The following are specific examples of the present invention.

Example 1 Cyclodextrin and Hiba oil were mixed at 8: 2 (weight ratio) to obtain an antibacterial agent. As the cyclodextrin, a mixture of maltosyl α-cyclodextrin, maltosyl β-cyclodextrin, dimaltosyl α-cyclodextrin, dimaltosyl β-cyclodextrin, and α-cyclodextrin was used.

A coating agent having the following composition was produced using the obtained antibacterial agent.

Composition of coating agent (unit is parts by weight)・ Antibacterial agent (average particle size of 10 μm or less) 3 ・ Shellac 28.5 ・ Ethyl alcohol 65.5 ・ Propylene glycol 3 Wet spunlace nonwoven fabric mainly composed of natural pulp The antibacterial coating agent containing Hiba oil thus obtained was coated and untreated (uncoated).

Next, a commercially available bread was wrapped with each of the prepared non-woven fabrics and further wrapped with a vinylidene chloride film, and allowed to stand in a room (20 ° C.) for 2 weeks, and the mold generation state was confirmed. Molds had molds on half of the bread (area of about 50%), whereas those with the coating treatment had molds on about 1 to 2%.

[0058]

As described in detail above, the coated product having antibacterial properties of the present invention can be applied to products of various materials including sheet products such as films.

Further, according to the coated product of the present invention, since a coating method using a printing method such as gravure printing, which has mass productivity, can be applied, it is possible to manufacture a product with low cost and good reproducibility.

In addition, according to the coated product of the present invention, since the antibacterial agent is applied through the binder resin, the antibacterial agent does not easily drop off even when exposed to water or other liquids, and under severe conditions. It is possible to use

Further, according to the coated product of the present invention, since the antibacterial agent having sustained release is used and the antibacterial effect is maintained for a long period of time, for example, household goods often used in an open environment for a long time, It can also be applied to products such as bedding.

Furthermore, according to the coated product of the present invention, the resistance of the surface coating is excellent and the antibacterial agent is firmly attached, so that it can be used as a raw material for products such as adhesive products which require secondary processing. Is.

Claims (8)

[Claims] 1. An antibacterial property obtained by applying an antibacterial coating agent containing a mixture of cyclodextrins and hiba oil, a binder resin and a solvent using a coating method. Coating products that have. 2. The coated product having antibacterial properties according to claim 1, wherein the coated product is a sheet-shaped product such as paper, film and non-woven fabric. 3. The coated product having antibacterial properties according to claim 1, wherein the coating is performed by a printing method. 4. The coated product having antibacterial properties according to claim 1, 2 or 3, wherein the binder resin is shellac, zein, methylcellulose or rosin. 5. The solvent according to claim 1, wherein the solvent is a mixed solvent of ethyl alcohol and propylene glycol, or a mixed solvent of them and water.
A coated product having the described antibacterial properties. 6. The antibacterial property according to claim 1, wherein the mixing ratio of the cyclodextrins and the hiba oil is 99% to 60%: 1% to 40%. Coating products with. 7. The particle size distribution of the mixture of cyclodextrin and hiba oil is in the range of 0.5 μm to 150 μm, and the maximum of the distribution is in the range of 3 μm to 15 μm. A coated product having antibacterial properties according to 2, 3, 4, 5 or 6. 8. The content of the mixture of the cyclodextrin and the hiba oil is 1% by weight to 40% by weight, and the content of the mixture is 1, 2, 3, 4, 5, 6 or 7. A coated product with antibacterial properties.