JPH0787840B2 - Human ovulation time measuring instrument - Google Patents

Description

Detailed Description of the Invention [Industrial applications]

 The present invention relates to a human ovulation time measuring device.

[Prior art]

Conventionally, for example, JP-A-60-188142-188148, JP-A-60-
190942-190944, JP-A-60-220052, JP-A-60-22774
6, JP-A-61-90651 to 90655, JP-A-61-137543 to 13754
5, as disclosed in JP-A-61-137554 and JP-A-61-217157, based on the equivalent DC resistance value of the vaginal wall of the mammal, to detect the ovulation time or the optimal fertilization period of the mammal A device for doing so has been proposed. This insemination suitable period detection device is a rod-shaped detection unit that can be inserted into the vagina of a mammal, a plurality of electrodes arranged at a position of the rod-shaped detection unit that can contact the mucous membrane of the vagina, and a voltage between the plurality of electrodes. And a sodium ion concentration detecting means including a resistance detecting device for detecting an electric resistance value between the electrodes; and an equivalent direct current resistance value of the vaginal mucosa detected by the resistance detecting device. In accordance with the above, there is provided display means for displaying this; and a hollow case for supporting the base end side of the rod-shaped detection section;

[Problems to be Solved by the Invention]

By the way, the above-mentioned device for detecting a suitable fertilization period for mammals can be used for humans. In this case, a person (female), unlike domestic animals such as cows and pigs, himself / herself inserts the rod-shaped detection portion into the vagina to measure the ovulation time. In the case of an ovulation timing measuring instrument for humans, as in the case of livestock such as cattle, the electrode part at the tip of the rod-shaped detection part is inserted to the measurement site such as the bottom of the vagina, and the electrode part is set as the measurement site. The most reliable measurement value can be obtained when contacted at a constant pressure. However, when a person (female) inserts the rod-shaped detection part into the vagina by himself, due to fear, etc., the insertion may be stopped before the electrode at the tip of the rod-shaped detection part is pressed against the bottom of the vagina, etc. It is often the case that the measurement is made at that point without being made If this is done, it is naturally impossible to obtain accurate measurement values.

[Object of the Invention]

The present invention has been made in view of the above problems, in which the electrode section in the rod-shaped detection section can obtain a measurement value only when the measurement section comes into contact with the measurement site at a pressure of a certain value or more, and an accurate measurement is performed. It is an object of the present invention to provide a human ovulation time measuring device capable of performing.

[Means for Solving the Problems]

The present invention, a rod-shaped detection unit that can be inserted into the vagina of a person, a plurality of electrodes arranged at a position where the rod-shaped detection unit can contact the vaginal mucosa, and to apply a voltage between the plurality of electrodes Means for detecting the sodium ion concentration in the vaginal mucosa of a human, including the voltage generating means and an impedance detecting device for detecting the impedance value between the electrodes, and the impedance of the vaginal mucosa detected by the impedance detecting device. Display means for displaying the state of the vaginal mucosa according to the value, the electrode is attached to the tip of the rod-shaped detection unit,
The rod-shaped detection unit holds a base end side of the rod-shaped detection unit by a holding unit so as to be slidable in the axial direction, and the holding unit further includes a spring for urging the rod-shaped detection unit in the distal direction, and the electrode from the electrode. The bar-shaped detecting means is provided, which is capable of connecting and disconnecting a circuit for sending a signal to the display means, and is equipped with a display trigger means having a contact point that opens when the bar-shaped detecting portion is biased in the tip direction by the spring. The above-mentioned object is achieved by a human ovulation timing measuring device characterized in that the state of the vaginal mucosa can be displayed by the display means when the pressure applied to the electrode of the part becomes a certain value or more. It is a thing.

[Action]

In this invention, since the measurement value is obtained only when a certain pressure or more is applied to the electrode of the rod-shaped detection portion, the user stops the insertion of the rod-shaped detection portion into the vagina on the way. In the case of a streak, a measured value cannot be obtained, and an accurate measured value can be obtained only when the contact pressure between the electrode of the rod-shaped detector and the vaginal wall exceeds a certain value.

【Example】

Embodiments of the present invention will be described below with reference to the drawings. In this embodiment, a rod-shaped detection unit 12 that can be inserted into a human vagina,
The rod-shaped detection unit 12, a pair of electrodes 14, 14 arranged at a position capable of contacting the mucous membrane of the vaginal floor of the vagina, a voltage generation means 16 for applying a voltage between the pair of electrodes 14, 14.
A sodium ion concentration detecting means 20 including an impedance detecting device 18 for detecting the impedance between the electrodes 14; and a state of the vaginal mucosa according to the impedance value of the vaginal mucosa detected by the impedance detecting device 18. And a holding unit 2 for supporting the base end portion 12B side of the rod-shaped detection unit 12 on one end side in the longitudinal direction.
4; display trigger means 25 for enabling the display means 22 to display the impedance value when the pressure applied to the rod-shaped detection portion 12 in the axial direction toward the base end portion 12B becomes a certain value or more. And a human ovulation timing measuring device is configured by; The pair of electrodes 14 and 14 are embedded in the tip portion 12A of the rod-shaped detection portion 12 and attached flush with the surface of the tip portion 12A. The rod-shaped detector 12 is held by the holder 24 so as to be slidable in the axial direction. The display trigger means 25 is attached to the holding portion 24 and includes a spring 26 for urging the rod-shaped detection portion 12 in the tip direction and the display means from the electrodes 14 and 14.
It is arranged at an intermediate position of a lead wire 28 for sending a signal to 22 and is openable when the lead wire 28 can be interrupted and the rod-shaped detecting portion 12 is biased in the distal direction by the spring 26. The contact points 30A and 30B are included. The rod-shaped detection unit 12 has a cylindrical shape except for the tip portion 12A, and the outer peripheral surface of the rod-shaped detection unit 12 excluding the outer surfaces of the electrodes 14 and 14 is made of a material having a low friction coefficient such as fluorine resin. Is covered by a coating 32. The lead wire 28 is arranged so as to pass through the inside of the pipe-shaped rod-shaped detection portion 12, and further extends from the base end portion 12B of the rod-shaped detection portion 12 into the holding portion 24. Here, when the spring 26 inserts the rod-shaped detection unit 10 into the vagina of a person (female) and the electrodes 14 and 14 come into contact with the mucous membrane at the bottom of the vagina, a contact pressure of a certain value or more is obtained. The spring constant is such that the contact points 30A and 30B are allowed to come into contact with each other by being compressed by the reaction force of the axial force applied to the tip of the rod-shaped detection unit 12. Therefore, the spring constant of the spring 26 is experimentally and empirically selected. In this case, the outer peripheral surface of the rod-shaped detecting portion 10 is covered with the coating 32 made of a material having a low friction coefficient, and even if the vaginal mucous membrane contacts the peripheral side surface of the rod-shaped detecting portion 12, a large resistance is not generated. On the other hand, when the electrodes 14, 14 at the tip of the rod-shaped detection unit 12 are pressed against the mucous membrane of the vaginal floor, the resistance generated in the axial direction of the rod-shaped detection unit 12 is very large. Therefore, the selection of the spring constant of the spring 26 is widened. In addition, the spring 26 is caused by the resistance applied to the circumferential side surface of the rod-shaped detection portion 12.
Is rarely accidentally closed and the contacts 30A and 30B are erroneously closed. Next, an electric circuit for detecting signal processing in this embodiment will be described. As shown in FIG. 2, the voltage generator 16 includes an AC generator 62, a voltage regulator 64, and a voltage comparator 66.
It has and. The AC generating means 62 is configured to include a rectangular wave oscillating circuit 62A and a 1/2 frequency dividing circuit 62B. The rectangular wave oscillating circuit 62A includes a shift circuit,
The frequency dividing circuit 62B divides the pulse output from the rectangular wave oscillating circuit 62A by 1/2 to form a stable rectangular wave. The voltage regulator 64 includes an inverter circuit for stepping down the power supply voltage supplied from the power supply battery 68 to a required voltage. The impedance detection device 18 includes a plurality of operational amplifiers OP1 to OP6 for detecting the impedance level of the detected part (vaginal mucosa) by the alternating current applied to the electrodes 14 and 14, and the display means 22 is The levels determined by the impedance detecting device 18 are displayed by the light emitting diodes DP1 to DP6 according to the respective levels. The display means 22 also includes a light emitting diode DPO for the power supply voltage check. In FIG. 2, reference numeral 18A indicates an equivalent circuit of the vaginal mucosa which is the detected part. More specifically, the impedance detection device 18
Is a resistor for dividing the voltage input from the voltage regulator 64 in order to determine the impedance level from the voltage signal output from the electrodes 14 and 14 via the resistor R10, the voltage follower VF and the diode D1.
R17 to R23 and operational amplifiers OP1 to OP6 for comparing each divided voltage with the voltage signal are provided. A characteristic element of the smoothing circuit SC for stabilizing the input voltage signals to the operational amplifiers OP1 to OP6 is connected to the negative side of the diode D1. The voltage of the voltage regulator 64 divided by the voltage dividing resistors R12 and R13 is applied to the smoothing circuit SC. Reference numerals BC1 and BC2 in the figure denote bypass capacitors for these voltage dividing resistors R12 and R13. The voltage comparison device 66 is for checking (diagnosing) the voltage drop of the power supply battery 68, and the operation switch 72
It is activated by turning on. The operation switch 72 also serves as an operation switch for operating the impedance detection device 18. Further, the voltage comparison device 66 uses a resistor R2 to diagnose the voltage of the power supply battery 68 input via the operation switch 72.
Operational amplifier OP7 for comparing 9, 30 and the voltage divided by resistors R29 and R30 with the output voltage of the voltage regulator 64.
As a result of comparison and diagnosis, a signal is output to the display means 22 via the diode D4 when the voltage is equal to or higher than a certain value. The reference symbols R30 to R36 in the figure denote the respective light emitting diodes DP0 to DP6.
It shows a resistor for dividing the voltage applied to. Further, reference numeral 66A indicates a rectangular wave oscillation circuit, the output of which is a diode D
It is connected to the output side of the diode D4 via 5 and is configured to be applied to the display means 22 only when the output of the diode D4 is not present, that is, when the output voltage of the power supply battery 68 is below a certain value. Here, the sum of the resistance values of the voltage dividing resistors R18 to R23 in the impedance detection device 18 is the electrode 14 in water,
It is set to be slightly smaller than the impedance value between 14. For example, in the case of a human, the body temperature is usually about 36.5 ° C, so the electrodes 14 and 14 are immersed in water at 36.5 ° C.
The impedance value is between 14 and 14. Here, the target water is drinking water for humans, such as tap water, well water, or water having an electrical resistance equal to this. In addition, the resistance value of the voltage dividing resistor R23 is
It is set to be almost equal to the impedance value between 4 and 14. Furthermore, the total sum of the resistance values of the partial pressure resistors R19 to R23 is set to be substantially equal to the impedance value between the electrodes 14, 14 in the human vaginal mucosa during ovulation. Furthermore, the sum of the resistance values of the partial pressure resistors R20 to R23 is the total amount of the electrodes 14, 14 in the human vaginal mucosa at the most suitable time for fertilization.
It is made to be substantially equal to the impedance value between them. Further, the sum of the resistance values of the partial pressure resistors R21 to R23 is set to be substantially equal to the maximum value of the impedance between the electrodes 14 and 14 in the vaginal mucosa in a state where the pregnancy probability is about 50% when a person is not ovulating. ing. Furthermore, the sum of the resistance values of the partial pressure resistances R22 and R23 is the electrode in the vaginal mucosa when a person cannot conceive during non-ovulation.
It is made equal to the impedance value between 14 and 14. The display means 22 includes light emitting diodes DP1 to DP6, which are windows 76A to 76F arranged on the surface of the holder 22 in an arc shape.
It is inserted from the back side to the outside so that the light emission can be visually recognized from the outside. Furthermore, the window 76G also has a light emitting diode DP0 for voltage checking.
Are arranged. On the surface of the holding part 24, the light emitting diodes DP1 to D are located near the six windows 76A to 76F arranged in an arc shape.
A symbol indicating the meaning when P6 lights up, that is, a state in which fertilization does not occur, a state in which fertilization is unlikely, a state suitable for fertilization, a state immediately before ovulation, depending on the impedance value between the electrodes 14 in the vaginal mucosa Symbols indicating the states such as “1” are arranged. Also, the light emitting diode DP0 for the battery check.
A push button 78 is arranged at a position close to the right side in the figure. The push button 78 is adapted to turn on the operation switch 72. Next, the process of detecting the ovulation time of a person using the apparatus of the above embodiment will be described. First, the rod-shaped detection unit 12 is inserted into the vagina of a person. The rod-shaped detection unit 12 is inserted into the vagina until its tip 12A contacts the vaginal mucosa at the bottom of the vagina. At this time, the electrodes 14 of the tip portion 12A are pressed against the vaginal mucous membrane, but when the pressure exceeds a certain value, the rod-shaped detection portion 12 resists the urging force of the spring 26 and reacts from the bottom of the vagina. It is pushed into the holding part 24 by force. When the amount of movement of the rod-shaped detection unit 12 in the proximal direction becomes a certain value or more, the contacts 30A and 30B come into contact, and the signal output circuit from the electrodes 14 and 14 to the impedance detection device 18 is closed. . At this time, by reading the display of the state of the vaginal mucosa on the display means 20, it is possible to determine whether fertilization is possible or not. More specifically, when the electrodes 14 and 14 are brought into contact with the vaginal mucosa with a pressure of a certain value or more, a voltage generated according to the impedance value between the electrodes 14 and 14 is applied to each operational amplifier OP1 via the diode D1. ~ Input to non-inverting input pin of OP6. On the other hand, the voltage divided by the resistors R17 to R23 is applied to the inverting input terminals of these operational amplifiers OP1 to OP6, and accordingly, the voltage value from the vaginal mucosa equivalent circuit 18A and each operational amplifier OP1 to OP6. Are compared and the comparison results are input to the corresponding light emitting diodes DP1 to DP6. in this case,
The voltage input to each inverting input terminal is from the operational amplifier OP6 to O.
The resistance is gradually increased toward P1 in accordance with the resistances R23 to R17, and is gradually increased. Therefore, one of the operational amplifiers OP6 to OP1 selectively outputs a signal according to the magnitude of the voltage value from the vaginal mucosa equivalent circuit 18A. For example, when the operational amplifier OP2 outputs the output signal, the operational amplifier OP3 passes through the light emitting diode DP2 and the resistor R3.
To the ground side of the power line. Therefore, the light emitting diode DP2 is turned on. Here, as described above, the sum of the resistance values of the voltage dividing resistors R18 to R23 is set to be substantially equal to the impedance value of water,
In addition, the sum of the resistance values of the voltage dividing resistors R19 to R23 is equal to the value in the state where the impedance of the vaginal mucosa is suitable for fertilization, and thus the ovulation time is indicated when the light emitting diode DP1 is turned on. Similarly, the light emitting diode DP
When 2 lights up, it indicates the time suitable for fertilization. When the impedance value between the electrodes 14 and 14 is larger than the impedance value in water, none of the operational amplifiers OP1 to OP6 outputs a signal, and therefore the light emitting diodes DP1 to DP6.
Will not light up. For example, when the electrodes 14 and 14 are not inserted into a person's vagina and are in the air, the impedance between the electrodes 14 and 14 naturally becomes larger than the impedance in water. When the operation switch 72 is turned on in this state,
When the output voltage of 68 is equal to or higher than a certain value, a current flows to the display means 22 via the voltage comparison device 66 and the diode D4, and the current is supplied to the ground side of the power supply line of the operational amplifier OP1 via the light emitting diode DP0 and the resistor R30. To do. Therefore, the light emitting diode DPO lights up, indicating that the voltage of the power supply battery 68 is equal to or higher than the specified value. Further, when the voltage of the power supply battery 68 becomes lower than the specified value, the voltage comparison device 66 does not output a signal. On the other hand, a rectangular wave oscillator circuit
Since 66A outputs a rectangular wave via the diode D5, when there is no output of the voltage comparison device 66, the output signal of the rectangular wave oscillation circuit 66A is the light emitting diode DP0 and the resistor R30.
Will be output to. Therefore, the light emitting diode DP0 blinks in response to the output signal of the rectangular wave oscillation circuit 66A, and indicates that the output voltage of the power supply battery 68 has become a certain value or less. Since the sum total of the resistance values of the voltage dividing resistors R21 to R23 is set equal to the maximum value of the impedance of the vaginal mucosa during the infertile period in the non-ovulatory state, the light emitting diode DP5 or DP6.
When is lit, it indicates a person's infertility. Further, since the light emitting diode DP5 represents a high level impedance value during the infertile period and the light emitting diode DP6 represents a low level impedance value during the infertile period, it is possible to determine whether or not ovulation is approaching or ovulation is completed. . The light emitting diodes DP4 and DP3 exhibit an unknown time period between the fertile and infertile, the so-called gray zone. Further, since the resistance value of the voltage dividing resistor R23 is set to be slightly larger than the impedance value in human blood,
Light emitting diode when electrodes 14, 14 are immersed in human blood
DP5 will be turned off. That is, by immersing the electrodes 14, 14 in blood, a zero level check of the ovulation timing detection device can be performed. According to the actual measurement by the present inventor, as shown in the right end of FIG. 4, in the case of a human, the impedance value of the vaginal mucosa is 1/3 of the impedance value from the zero point (impedance value of blood) during non-ovulation. Shows a stable curve that periodically increases and decreases with the passage of time, but the impedance value begins to increase 72 to 120 hours before ovulation, approaches the impedance value in water infinitely, and the impedance of water immediately before ovulation The value is almost equal to the value, then decreases sharply, and reaches the bottom value in a few hours. Here, in the case of human artificial insemination, the injection of sperm into the vagina is performed about 7 to 5 hours before ovulation in the case of ordinary liquid sperm. Since the relationship between the impedance value of the vaginal mucosa of a person and time is constant, the timing of sperm injection can be determined by setting the time when the light emitting diode DP2 is turned on 7 to 5 hours before, as described above. In the case of frozen spermatozoa, injection at 2 hours before ovulation can ensure the highest conception rate. This is the case of frozen sperm.
citation) and the capsule that covers the sperm (sperm coat antigen,
This is because the plasma membrane and the in vitro membrane) have fallen off, and it is in a state of being easily fertilized immediately as compared with liquid or live sperm. Therefore, the injection of the frozen sperm thawed may be performed when the light emitting diode DP1 is turned on. For frozen sperm,
Do not become pregnant when any of the light emitting diodes DP2 to DP6 are lit. Next, reference examples shown in FIGS. 5 and 6 will be described. In this reference example, a pressure sensor 34 that outputs a signal at a position between the base end portion of the rod-shaped detection unit 12 and the holding unit 22 when the axial pressure applied to the rod-shaped detection unit 12 reaches a certain value or more. The output signal from the pressure sensor 34 causes the lead wire 28
The display trigger means is composed of a switch 36 for closing the switch. In the case of this reference example, the movement range of the rod-shaped detection unit 12 can be set to a narrow range for turning the pressure sensor 34 on and off, and since no spring or the like is used, there is an advantage that the durability is high. Further, since there is no problem such as a spring fatigue, the reliability of detection is increased. In the above embodiment, the display means 22 displays the state of the vaginal mucous membrane only while the display trigger means 25 is turned on. For example, as shown in FIG. It is advisable to provide a hold circuit 38 for holding the display according to the impedance detected when the signal of (3) is input for a certain period of time. In this way, even if the measurer releases the push button 72, the light emitting diode corresponding to a certain time, for example, about 10 seconds.
Since the light emission of DP1 to DP6 is maintained, the measurer can reliably read the measurement state. In the embodiment of the present invention, the impedance detection device 18 is used to detect the magnitude of the impedance between the electrodes 14, 14 in the vaginal mucosa, but the present invention is not limited to this, and it is necessary. That is, any impedance detection device can be used as long as it can detect whether or not the impedance value corresponds to the level as it is or appropriately divided. Further, in the embodiment of the present invention, the display means 22 is composed of a plurality of light emitting diodes DP1 to DP6, but the present invention is not limited to this, and the maximum and minimum values of the impedance of the vaginal mucosa are shown. Anything can be displayed as long as it can be displayed appropriately. Therefore, the display means 22 may be an ordinary meter or the like for displaying the impedance value. In this embodiment, the impedance of water is set to the maximum value and the impedance of blood is set to the minimum value, and the space between them is appropriately divided and can be directly displayed on the meter. Further, when using a light emitting diode or the like, the number is not limited to six in the embodiment, and may be three or two, or even seven or more.

【The invention's effect】

Since the present invention is configured as described above, the rod-shaped detection unit,
Since it cannot be measured until the electrode is inserted until it contacts the vaginal mucosa with a pressure of a certain value or more, it has an excellent effect that erroneous measurement due to insertion or insufficient contact pressure can be prevented.

[Brief description of drawings]

FIG. 1 is a partial cross-sectional plan view showing an embodiment of the human ovulation timing measuring apparatus according to the present invention, FIG. 2 is an electric circuit diagram showing the electrical components of the embodiment, and FIG. 3 is the same. Block diagram, Fig. 4 is a diagram showing changes in impedance value of human vaginal mucous membrane with time, Fig. 5 is a sectional view of main parts showing a reference example of a human ovulation timing measuring instrument, and Fig. 6 is a reference example. FIG. 7 is a circuit diagram of a main part of an electric circuit, and FIG. 7 is a block diagram showing another embodiment of the present invention. 10 …… fertilization appropriate period detection device, 12 …… rod-shaped detection part, 12 A …… hemispherical tip, 14, 14 …… electrode, 16 …… voltage generation means, 18 …… impedance detector, 20 …… sodium ion concentration detection Means, 22 ... display means, 24 ... holding part, 25 ... display trigger means, 26 ... spring, 28 ... lead wire, 30A, 30B ... contact, 32 ... coat, 34 ... pressure sensor, 36 …… Switch, 38 …… Hold circuit.

Claims (1)

[Claims] 1. A rod-shaped detection unit that can be inserted into a person's vagina, a plurality of electrodes arranged at positions of the rod-shaped detection unit that can contact the vaginal mucosa, and a voltage is applied between the plurality of electrodes. Means for detecting sodium ion concentration in the vaginal mucous membrane of a human including a voltage generating means for detecting the impedance value between the electrodes, and the vaginal mucosa detected by the impedance detecting device. And a display unit for displaying the state of the vaginal mucosa according to the impedance value, the electrode is attached to the tip of the rod-shaped detection unit,
The rod-shaped detection unit holds a base end side of the rod-shaped detection unit by a holding unit so as to be slidable in the axial direction, and the holding unit further includes a spring for urging the rod-shaped detection unit in the distal direction, and the electrode from the electrode. The bar-shaped detecting means is provided, which is capable of connecting and disconnecting a circuit for sending a signal to the display means, and is equipped with a display trigger means having a contact point that opens when the bar-shaped detecting portion is biased in the tip direction by the spring. An ovulation timing measuring instrument for human use, characterized in that the state of the vaginal mucous membrane can be displayed by the display means when the pressure applied to the electrode of the part becomes a certain value or more.