JPH07324005A - Disinfectant composition and disinfecting method using the same - Google Patents

Abstract

PURPOSE:To obtain a disinfectant composition having excellent durability in disinfecting effect, suitably useful for preventing so-called hospital-acquired infection and to provide a disinfecting method using the disinfectant composition. CONSTITUTION:A hydrophilic polymer which is a linear polymer of 2- hydroxyethyl methacrylate and or a copolymer of 2-hydroxyethyl methacrylate and another hydrophilic and/or hydrophobic monomer and is capable of forming a water-insoluble film having 30-50% water content in an amount of 100 pts.wt. and a polyvinyl alcohol having 5-7% degree of saponification in an amount of 1-100 pts.wt. are dissolved in an alcoholic solvent and a disinfectant is dissolved or dispersed into the solution to provide the objective disinfectant composition. A prescribed target material to be disinfected is treated with the composition to form a coating film containing a fungicide fixed to the surface of the objective material with the hydrophilic polymer.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a disinfectant composition that can be suitably used in the medical, food, research, and other fields and a disinfection method using the same, and in particular, a disinfectant having an excellent disinfection effect. The present invention relates to a composition and a disinfection method using the composition.

[0002]

BACKGROUND ART In recent years, in hospitals and the like, in order to prevent so-called nosocomial infection, disinfection of in-hospital equipment and its environment has been carefully performed. Then, in general, an aqueous solution of various germicides or an alcohol solution is used for this disinfection treatment. However, since the disinfecting method using such a bactericide lacks sustainability, it is necessary to frequently perform the disinfecting treatment in order to obtain the disinfecting effect over a long period of time. It was tedious and labor intensive.

Therefore, as one of the attempts to improve the sustainability of such a disinfecting effect, Japanese Patent Application Laid-Open No. 61-233.
No. 602 discloses a liquid composition prepared by dissolving a mixture of a film-forming water-insoluble copolymer and a bactericide in a volatile solvent such as alcohol. Since this composition contains a film-forming polymer, a disinfecting treatment with the composition causes a film containing a bactericide to be formed on the surface of an object to be disinfected,
It is intended to improve the sustainability of the disinfecting effect by exerting the bactericidal effect and preventing the elution of the bactericidal agent contained in the film by suppressing the swelling of the polymer. However, in such a liquid composition, since the film-forming copolymer constituting the liquid composition is obtained by copolymerizing a hydrophilic monomer and a hydrophobic monomer, the water content of the film formed during disinfection treatment is Since it is less than 30%, there is a problem that the effect of the disinfectant contained in the film cannot be sufficiently exerted.

On the other hand, a method of kneading a silver-based inorganic bactericidal agent into synthetic fibers to produce antibacterial fibers to obtain a gown or curtain having antibacterial properties has been studied.
In the antibacterial product obtained by such a method, the antibacterial effect is excellent in sustainability, but the disinfecting effect is not sufficient, and only the growth of bacteria is suppressed. Kashidashi, the silver-based inorganic bactericide dispersed throughout the fiber,
This is because only a small amount appears on the fiber surface, and therefore, strong bactericidal properties cannot be exhibited.

Further, usually, when a bactericide is continuously used for a long period of time, a resistant bacterium may appear, and the appearance of such a resistant bacterium significantly attenuates the effect of the bactericide, which is a serious medical problem. Has become. Therefore, there is a strong demand for the development of a bactericide that hardly causes the appearance of resistant bacteria.

[0006]

The present invention has been made in view of such circumstances, and the problem to be solved by the present invention is that the disinfecting effect, that is, the sterilizing effect can be maintained for a long period of time, and the so-called in-hospital An object of the present invention is to provide a disinfectant composition that is advantageously used for infection and the like, and a disinfection method using the same.

[0007]

SOLUTION: In order to solve the above problems,
In the present invention, a linear homopolymer of 2-hydroxyethyl methacrylate or a copolymer of 2-hydroxyethyl methacrylate and other hydrophilic monomer and / or hydrophobic monomer, having a water content of 30 to 50%
100 parts by weight of a hydrophilic polymer having the ability to form a water-insoluble film and 1 to 100 parts by weight of polyvinyl alcohol having a saponification degree of 5 to 75% are dissolved in an alcohol solvent, and a bactericide is added to the solution. The gist is a disinfectant composition characterized in that is dissolved or dispersed.

According to a preferred embodiment of the disinfectant composition according to the present invention, a formaldehyde donor is used as the disinfectant. According to a different preferred embodiment of the disinfectant composition according to the present invention, the hydrophilic polymer is present in a concentration of 0.05 to 5%, and further according to a desirable embodiment of the disinfectant composition according to the present invention. For example, the bactericide is contained in a proportion of 1 to 100% by weight based on the total polymer.

In the present invention, the disinfectant composition is treated with the disinfectant composition to fix the disinfectant on the surface of the disinfectant by the hydrophilic polymer. A gist is also a disinfection method characterized by forming a coating film containing.

[0010]

[Operation / Effect] In short, in the disinfectant composition according to the present invention, a specific hydrophilic polymer having the ability to form a water-insoluble film and a predetermined polyvinyl alcohol are dissolved in an alcohol solvent. The bactericide is dispersed in the solution, so that the problems in the conventional disinfectant composition can be solved.

That is, when the disinfecting treatment is carried out with such a disinfectant composition, a water-insoluble polymer film is formed on the surface of the disinfecting object after the alcoholic solvent is evaporated and the disinfectant is contained. Therefore, a disinfecting effect (bactericidal effect) having excellent sustainability can be obtained.

More specifically, since an alcoholic solvent such as ethanol for disinfection is used as a solvent in the disinfectant composition of the present invention, when the disinfectant composition is applied, first, The strong bactericidal effect of the alcoholic solvent is exhibited. Then, when the alcoholic solvent evaporates, a water-insoluble polymer coating containing a bactericide (hereinafter referred to as a polymer coating) is formed in a predetermined thickness on the surface to be disinfected by the hydrophilic polymer. As the hydrophilic polymer forming the polymer film, a hydrophilic polymer which is hydrophilic and has a high swelling property, and the water content of the polymer film formed by the polymer is an appropriate value of 30 to 50% is selected. Therefore, the polymer coating contains an appropriate amount of water, and thus the bactericidal effect of the bactericidal component dispersed in the coating is advantageously exhibited. Moreover, the degree of saponification is 5
75% polyvinyl alcohol is hydrophilic polymer 10
Since the polymer is added at a ratio of 1 to 100 parts by weight with respect to 0 parts by weight, the polymer coating formed has excellent uniformity. Therefore, the polymer coating formed is tough and resistant to peeling, and the bactericidal component is retained therein for a long period of time, so that the sustainability of the bactericidal effect can be advantageously achieved.

Further, in the present invention, a formaldehyde donor is preferably used as a bactericide, and when used as a bactericide, such a formaldehyde donor releases formaldehyde and the generated formaldehyde has a bactericidal action. Is to demonstrate. Moreover, since formaldehyde is unlikely to produce resistant bacteria, the problem of appearance of resistant bacteria due to continuous use as in the case of using conventional disinfectant compositions is not caused.

As described above, the disinfectant composition according to the present invention is a textile product such as gowns, curtains, bed sheets, footwear such as slippers and shoes, beds, and various equipment used in hospitals and the like. It can be preferably used for disinfecting hospital environments such as walls, pillars, elevators, toilets, etc. Moreover, it can solve the problems that conventional disinfectants have, and has excellent sustainability in its disinfecting effect. It has become possible to exhibit its sexuality.

Further, according to the disinfection method of the present invention, the object to be disinfected is treated by spraying or applying the above-mentioned disinfectant composition. After the strong bactericidal effect is exhibited, and then the alcoholic solvent is evaporated, the water-insoluble polymer film containing the bactericidal component formed on the surface of the disinfection target exhibits an excellent bactericidal effect. Of. And since the polymer coating formed here is a strong one that is hard to peel off, the bactericidal effect is maintained for a long period of time, and therefore, according to the disinfection method according to the present invention, the disinfection is repeated many times. The annoyance of the conventional disinfection method of performing the treatment can be advantageously eliminated. Furthermore, according to a preferred embodiment of the present invention, a formaldehyde donor is used as a bactericide, and the problem of appearance of resistant bacteria due to continuous use can be advantageously solved.

[0016]

Concrete Structure By the way, the hydrophilic polymer constituting the disinfectant composition according to the present invention is
It is used for the purpose of immobilizing the bactericide contained in the disinfectant composition, and as such a hydrophilic polymer, a linear homopolymer of 2-hydroxyethyl methacrylate or 2-hydroxyethyl methacrylate and other A hydrophilic polymer which is a copolymer with a hydrophilic monomer and / or a hydrophobic monomer and has an ability to form a water-insoluble film having a water content of 30 to 50% is used. Further, as the hydrophilic polymer, an alcoholic solvent such as methanol, ethanol, or those obtained by adding isopropanol or water thereto, particularly preferably those soluble in ethanol for disinfection are used. As the other hydrophilic monomer, acrylamide, N, N′-dimethylacrylamide, methacrylic acid, acrylic acid and the like can be mentioned, and as the hydrophobic monomer, alkyl methacrylate, alkyl acrylate, styrene and the like can be mentioned. I can name it. Further, vinyl acetate can be used as a copolymerization monomer.

The water content of the polymer coating formed by such a hydrophilic polymer must be within the range of 30 to 50%, preferably 33 to 40, in the state where the disinfectant component is not contained. %. If the water content is less than 30%, the bactericidal effect cannot be sufficiently exerted, and if the water content exceeds 50%, the swelling of the coating becomes excessive and the durability is Because it will decrease.

The following method is used to measure the water content. That is, a methanol solution containing 3% by weight of a polymer was prepared and poured into a petri dish,
Evaporate the solvent to form a film. And
This film was immersed in distilled water at 20 ° C. for 12 hours or more, then taken out with tweezers, the surface water was quickly wiped off with a filter paper, and then weighed. The weight at this time was taken as the wet weight. The film in the water-containing state was dried at 60 ° C. for 12 hours or more using a dryer, and then weighed, and the weight at this time was defined as the dry weight. Then, the water content is calculated by the following formula. Moisture content (%) = {(wet weight-dry weight) / wet weight} × 100

By the way, as the hydrophilic polymer used in the present invention, a linear homopolymer of 2-hydroxyethyl methacrylate is particularly preferable, and its water content is in the range of 30 to 40%. When such a homopolymer is used, the bactericidal effect is high, the washing resistance is excellent, and the film formed on the surface to be sterilized gives a dry feel. Furthermore, when it is applied to textile products, it becomes soft when exposed to moisture, and therefore it is extremely suitable for disinfecting sheets, gowns and the like.

In addition, polyvinyl alcohol is used in the disinfectant composition according to the present invention, whereby the polymer coating formed by the hydrophilic polymer becomes uniform. Saponification of this polyvinyl alcohol The degree is usually 5 to 75%, preferably 10 to 50%
It is said that If the saponification degree is less than 5%, the effect of enhancing the uniformity of the polymer coating formed will be insufficient, and if it exceeds 75%, the water resistance of the formed polymer coating will be significantly reduced. Because.

On the other hand, as the bactericide constituting the disinfectant composition according to the present invention, chlorhexidine gluconate, polyhexamethylene biguanide, benzalkonium chloride,
Cetylpyridinium chloride, dialkyldimethylammonium chloride, alkylpolyaminoethylglycine hydrochloride, thiabendazole, paraoxybenzoic acid ester, hexachlorophene, formaldehyde donor, and the like can be mentioned, and one or more of them can be used in combination. Be done.

In the present invention, a formaldehyde donor is advantageously used, and as the aldehyde donor, specifically, 2-bromo-2-
Nitropropane-1,3-diol (Bronopol: manufactured by Midori Cross Co., Ltd.), 1- (3-chloroallyl)-
3,5,7-Triaza-1-azonia adamantan chloride (Dausil 200: Dow Chemical Co., Ltd.), dimethylol-5,5-dimethylhydantoin (glidant: Lonza Co., Ltd.), 1-hydroxymethyl-
5,5-dimethylhydantoin, 3-hydroxymethyl-5,5-dimethylhydantoin, N, N'-methylenebis [N '-[1- (hydroxymethyl) -2,5-dioxo-4-imidazolidinyl] urea] ( (Jermal 115: manufactured by SUTTON LABO. INC.), Hexahydro-1,3,5-tris (2-hydroxyethyl) -s-triazine, hexahydro-1,3,5-triethyl-s-triazine and the like.

Further, a silver-based inorganic bactericidal agent, that is, an inorganic bactericidal agent carrying silver can also be used as a bactericidal agent in the disinfectant composition according to the present invention. It should be noted that the silver-based inorganic bactericidal agent referred to here includes silver, or those in which copper, zinc or the like is supported together with silver. Specifically, as a silver-based inorganic bactericide, zeolite in which silver ions are supported by ion exchange (manufactured by Shinagawa Fuel Co., Ltd.), silver in which calcium phosphate is adsorbed (manufactured by Sangi Co., Ltd.), zirconium phosphate On which silver ions were carried by ion exchange (Toagosei Kagaku Co., Ltd.), on which a silver complex was adsorbed on silicon oxide (SiO ₂ ) (Matsushita Electric Industrial Co., Ltd.), and silver oxide was dissolved in the glass component. Examples thereof include those manufactured by Ishizuka Glass Co., Ltd., those prepared by adsorbing silver ions on a titania-based carrier, and the like.

Furthermore, Staphylococcus (Staphylococcus), which is not effective only with the above-mentioned silver-based inorganic bactericide, can be obtained.
When many Gram-positive bacteria such as genus cus) are sterilized, chlorhexidine hydrochloride may be used together.

As a solvent for dissolving the water-soluble polymer, an alcoholic solvent such as ethanol, methanol, or those obtained by adding isopropanol or water to them is used. From the viewpoint of bactericidal effect, ethanol is preferably used, and more preferably, disinfecting ethanol having an ethanol concentration of 70 to 85% by weight is advantageously used. In addition, any of these alcoholic solvents to which a solvent other than alcohol such as dimethylformamide or dimethylsulfoxide is added may be used.

The hydrophilic polymer is dissolved in the alcoholic solvent, and the disinfectant is mixed and dispersed to prepare the disinfectant composition according to the present invention. Of course, the hydrophilic polymer and the disinfectant are simultaneously added to the alcoholic solvent and dissolved or dispersed, or the disinfectant and the alcohol are added to the hydrophilic polymer solution polymerized in the solvent to obtain the desired disinfection. Needless to say, even if the agent composition is prepared, there is no problem.

In the disinfectant composition according to the present invention prepared as described above, the concentration of the hydrophilic polymer in the composition is usually 0.05 to 5% by weight, preferably 0.15. ~ 3% by weight. This is because when the polymer concentration is less than 0.05% by weight, the fixing effect of the bactericide becomes insufficient, while when it exceeds 5% by weight, the viscosity of the disinfectant composition increases. This is because it becomes difficult to perform disinfection. In addition, polyvinyl alcohol is based on 100 parts by weight of the hydrophilic polymer,
1 to 100 parts by weight. When the amount of polyvinyl alcohol is less than 1 part by weight, the effect of enhancing the uniformity of the polymer film formed cannot be sufficiently exerted, and when it exceeds 100 parts by weight, the water resistance of the polymer film formed is high. Sex decreases. Further, the concentration of the bactericide contained in the disinfectant composition according to the present invention is 0.01 to 5% by weight, preferably 0.05 to 3% by weight.
The ratio of the hydrophilic polymer and the bactericide contained in the disinfectant composition is about 1 to 100 parts by weight, preferably 3 to 50 parts by weight, based on 100 parts by weight of the hydrophilic polymer. To be a part. This is because if the proportion of the bactericide is too low, the bactericidal effect cannot be sufficiently obtained.
Further, if the proportion of the bactericide is too high, the bactericide on the disinfected surface becomes excessively large, and problems such as insufficient fixation of the bactericide occur.

[0028]

EXAMPLES In order to clarify the present invention in more detail, some examples of the present invention will be shown below.
It goes without saying that the present invention is not limited by the description of such embodiments. In addition to the following embodiments, the present invention further includes various changes and modifications based on the knowledge of those skilled in the art, in addition to the above specific description, without departing from the spirit of the present invention. It should be understood that improvements and the like can be added.

Example 1 First, a stirrer and a Dimroth were set in a 500 mL three-necked round bottom flask, the inside was thoroughly replaced with nitrogen, and then 2-hydroxyethyl methacrylate (Wako Pure Chemical Industries, Ltd. (Manufactured by the company): 50.01 g, methanol (manufactured by Wako Pure Chemical Industries, Ltd.): 200 mL, and 2,
2'-Azobis (isobutyronitrile): 0.63 g was charged, and polymerization was carried out at a temperature of 60 ° C for 3 hours while stirring. Then, the obtained polymerization reaction product solution was cooled and then further diluted with 100 mL of methanol. Then, the methanol solution of the linear 2-hydroxyethyl methacrylate polymer thus obtained was gradually added to 10 L of ethyl acetate (manufactured by Wako Pure Chemical Industries, Ltd.) while the linear 2-hydroxyethyl methacrylate was added. The methacrylate polymer was reprecipitated. Then, the precipitate was filtered and then dried under reduced pressure to obtain 35.5 g of linear 2-hydroxyethyl methacrylate homopolymer. The water content of the polymer thus obtained was measured and found to be 38%.

Next, the obtained linear 2-hydroxyethyl methacrylate homopolymer: 0.25 g and polyvinyl alcohol having a saponification degree of 38.3 mol% (LM-
10HD: manufactured by Kuraray Co., Ltd.): 0.05 g, and 2-bromo-2-nitropropane-1,3-diol (bronopol: manufactured by Midori Cross Co., Ltd.) as a bactericide: 0.
10 g was dissolved in 80% by weight concentration of disinfecting ethanol (Japanese Pharmacopoeia: manufactured by Amaku Chemical Industry Co., Ltd.): 100 g to prepare an intended disinfectant composition. Next, this disinfectant composition solution was applied on both sides of three slide glasses three times each and air dried overnight. At this time,
When the polymer coating formed on the slide glass was observed, it was uniform.

Then, on a petri dish (diameter 90 mm), 1
A polyvinyl chloride wrap cut into a size of 50 mm × 150 mm is laid, the slide glass is placed on the wrap, and Staphylococcus aureus IFO 13276 is placed on the wrap.
Bacterial solution (7.6 × 10 ^{5 /} mL): 0.2 mL each,
It was placed on each sterilized slide glass. Then, the slide glass was wrapped with the wrap so that the bacterial solution uniformly contacted the slide glass, and then the lid of the petri dish was closed. This was placed at 23 ° C. for 6 hours and then 4.8.
Rinse the slide glass and wrap with mL of physiological saline, incubate this on tryptosoy agar medium, and measure the viable cell count per slide glass. It was found that the effect (disinfection effect) was obtained.

Comparative Example 1 0.25 g of linear 2-hydroxyethyl methacrylate homopolymer obtained in the same manner as in Example 1 and 2-bromo-2-nitropropane-1,3-as a bactericide
Diol (Bronopol: manufactured by Midori Cross Co., Ltd.):
0.10 g and 80% by weight concentration of disinfecting ethanol:
It melt | dissolved in 100 g and prepared the composition of the target comparative example. This was applied to both sides of three slide glasses three times each and then air-dried overnight. At this time, when the polymer coating formed on the slide glass was observed, it was extremely uneven. Then, 0.2 mL each of Staphylococcus aureus IFO 13276 bacterial solution (7.6 × 10 ^{5 /} mL) was placed on each of the slide glasses, and the viable cell count was examined in the same manner as in Example 1 below.
For each slide glass, 30, 100,
It was 24, and the result that the bactericidal effect was insufficient was obtained.

Comparative Examples 2 and 3 Linear 2-hydroxyethyl methacrylate homopolymer prepared by the same method as in Example 1 (0.2 g) and dimethylol-5,5'-dimethylhydantoin ( Glidant: manufactured by Lonza Co., Ltd.): 0.1 g
And 80% by weight ethanol for disinfection: 22.5 g
To prepare a composition of Comparative Example 2. Then, the composition is applied to both sides of the slide glass once,
After air-drying this overnight, observation of the polymer coating formed on the glass slides revealed that they were extremely non-uniform. Further, as Comparative Example 3, dimethylol-5,
A composition of Comparative Example 3 was prepared by dissolving only the hydrophilic polymer in 80% by weight concentration of ethanol for disinfection without adding 5′-dimethylhydantoin. Then, it was applied to a slide glass in the same manner as above. Five samples were prepared for each of Comparative Examples 2 and 3. Then, as in Example 1, Staphyl was added to the slide glass.
0.2 mL of each ococcus aureus IFO 13276 bacterial solution was placed, and the viable cell count after 6 hours was examined in the same manner as in Example 1, and the results are shown in Table 1 below.

[0034]

[Table 1]

Examples 2 to 6 Linear 2-hydroxyethyl methacrylate homopolymer obtained in the same manner as in Example 1: 0.5 g, and polyvinyl alcohol having a degree of saponification of 43.6 mol% (LM-10).
H: Kuraray Co., Ltd.): 0.03 g and a predetermined bactericide: 0.5 g were dissolved in 100 g of a disinfecting alcohol having a concentration of 80% by weight to obtain a desired disinfectant composition. Then, the bactericidal effect test was performed in the same manner as in Example 1 and the results are shown in Table 2. As the bactericide, polyhexamethylene biguanide (Cosmocil CQ: manufactured by Zeneca Corporation) was used in Example 2 and 2 in Example 3.
-Bromo-2-nitropropane-1,3-diol (Bronopol: manufactured by Midori Cross Co., Ltd.), dimethylol-5,5-dimethylhydantoin (Glydant: manufactured by Lonza Co., Ltd.) in Example 4, and Example 5 Chlorhexidine hydrochloride (manufactured by Tokyo Chemical Industry Co., Ltd.) was used in Example 6
Then, 10 wt% concentration of benzalkonium chloride (manufactured by Wako Pure Chemical Industries, Ltd.) was used.

Comparative Example 4 In the above example, except that no fungicide was added,
The compositions of Comparative Examples were prepared under the same conditions as in Examples 2 to 6 above, and the bactericidal effect test was conducted in the same manner. The results are shown in Table 2 below.

[0037]

[Table 2]

Examples 7 to 9 Linear 2-hydroxyethyl methacrylate homopolymer obtained in the same manner as in Example 1 (1.0 g) and polyvinyl alcohol (LM-10 having a saponification degree of 38.3 mol%).
HD: manufactured by Kuraray Co., Ltd.): 0.05 g and a predetermined bactericide, ethanol for disinfection having a concentration of 80 wt%: 100 g
To prepare the desired disinfectant composition. Then, the bactericidal effect was examined in the same manner as in Example 1, and the results are shown in Table 3 below. As the bactericide, in Example 7, 2-bromo-2-nitropropane-1,3-diol (Bronopol: manufactured by Midori Cross Co., Ltd.): 0.75 g
In Example 8, 2-bromo-2-nitropropane-
1,3-diol: 0.10 g, and in Example 9, polyhexamethylene biguanide (Cosmocil CQ: manufactured by Zeneca Corporation): 0.10 g were used.

Comparative Example 5 A target composition was prepared in the same manner as in Examples 7 to 9 except that no bactericide was added, and its bactericidal effect was examined. The results are shown in Table 3 below. It was

[0040]

[Table 3]

Examples 10 to 15 and Comparative Examples 6 to 12 8% of the disinfectant composition having the composition (weight basis) shown in Table 4 below was used.
Each was prepared using 0% by weight concentration of disinfecting ethanol as a solvent. Then, this was placed in a pump type spray container, and using this, it was sprayed on a slide glass and a polymethylmethacrylate resin plate. Then, after air-drying them, the state of the polymer coating containing the formed bactericide and its wet abrasion resistance (water resistance) were examined, and the results are also shown in Table 4 below. In addition, the state of the coating film was examined for uniformity and evaluated in four stages, and ◎:
Excellent, ○: Good, ×: Not shown. Further, the wet abrasion resistance of the polymer coating is that after being disinfected, an air-dried glass slide or a polymethylmethacrylate resin plate is immersed in water for 2 minutes and then rubbed with a finger, which does not come off even if strongly rubbed. ⊚, those that hardly peeled off even when strongly rubbed were evaluated as ◯, those that peeled off when slightly rubbed a little were evaluated as Δ, and those easily peeled off were evaluated as x.

[0042]

[Table 4] PHEMA: polyhydroxyethylmethacrylate PVA: polyvinyl alcohol bronopol: 2-bromo-2-nitropropane-1,
3-diol

Claims (5)

[Claims] 1. A linear homopolymer of 2-hydroxyethyl methacrylate or a copolymer of 2-hydroxyethyl methacrylate and other hydrophilic monomers and / or hydrophobic monomers, wherein the water content is 30 to 50%. 100 parts by weight of a hydrophilic polymer having an ability to form an insoluble film and 1 to 100 parts by weight of polyvinyl alcohol having a saponification degree of 5 to 75% are dissolved in an alcohol solvent, and a bactericide is dissolved therein. Alternatively, a disinfectant composition characterized by being dispersed. 2. The disinfectant composition according to claim 1, wherein the bactericide is a formaldehyde donor. 3. The hydrophilic polymer is 0.05 to 5%.
Claim 1 or Claim 2 which is made to exist in the density of
The disinfectant composition according to. 4. The disinfectant is 1 to all polymers.
The disinfectant composition according to any one of claims 1 to 3, which is contained at a rate of 100% by weight. 5. A disinfectant composition according to any one of claims 1 to 4 is used to treat an object to be disinfected so that it is fixed to the surface of the object to be disinfected with the hydrophilic polymer. A disinfection method comprising forming a coating film containing the bactericide.