JPH0710709A - Vermin repellent - Google Patents

Abstract

PURPOSE:To obtain a vermin repellent having excellent air-mediated repelling effect or further contact repelling effect, exhibiting strong vermin repelling effect and keeping its effect over a long period. CONSTITUTION:This vermin repellent contains at least one kind of organic hydroperoxide selected from menthane hydroperoxide, thujane hydroperoxide, carane hydroperoxide, bornane hydroperoxide, p-cymene hydroperoxide and cumene hydroperoxide as an active component or contains at least one kind of the hydroperoxide and at least one kind of compound selected from vaporthrin, N,N-diethyl-m-toluamide, peryllaldehyde and geraniol as active components.

Description

Detailed Description of the Invention

[0001]

The present invention relates to sanitary pests such as cockroaches, for example, German cockroaches, American cockroaches, and American cockroaches, blood-sucking and biting pests such as mosquitoes, fleas, lice, mites, etc. The present invention relates to a repellent for clothes pests and the like.

[0002]

2. Description of the Related Art Blood-sucking insects such as mosquitoes, flies, gnats, fleas, etc. inhabit a large amount in tropical regions and temperate regions, but depending on the species, they are often found in cold regions as well, and camping, hiking, fishing, golf, gardens. Attacks or blood-sucks the exposed skin surface when playing, outdoor recreation such as yachting, or when working on farms, fields, or power development areas in the mountains, and it is uncomfortable and sometimes infectious diseases and climate. It may also be a vector for the disease. In addition to these blood-sucking and biting insects, the damage caused by ticks has been increasing in recent years, and there are many types of diseases transmitted by these pests, including malaria, yellow fever, proboscis fever, filaria, rash, and tsutsugamushi. Diseases are well known. In addition, it is known that, in addition to itching and redness associated with blood sucking and biting, it may cause inflammation or an asthma attack. In addition, cockroaches directly and indirectly mediate pathogenic bacteria, and recently invaded so-called OA devices and caused damage.

In order to prevent these damages, insecticides are generally used, but the pesticides of interest are diverse, the ecosystem is complicated, and the growth rate is high. Complete control by is difficult. Further, it is environmentally unfavorable to use a large amount of insecticide at a high concentration over a wide range. Therefore, repellents are widely used to prevent insect damage caused by these harmful insects. Generally, amides, esters, glycols, etc. are said to be effective as repellents against pests, and among them, N, N-diethyl-m-toluamide (hereinafter sometimes abbreviated as DET) is the main component. Formulations are well known, for example, JP-A-56-10104 and JP-A-56-73008.
JP, JP-A-56-15203, JP-A-59-
It is reported in Japanese Patent Laid-Open No. 199602, Japanese Patent Laid-Open No. 60-61509, and the like. Also, insecticides, especially 1 among them
-Ethynyl-2-methyl-2-pentenyl-2,2-dimethyl-3- (2'-methyl-1'-propenyl) -cyclopropane-1-carboxylate (hereinafter referred to as vaporthrin) has a pest repellent effect. It is also known to have such compounds, and a preparation using this is disclosed in, for example, JP-A-56-9280.
3, JP-A-60-139606, JP-A-1
-27042, etc.

[0004]

As described above, insecticides are often used as repellents for cockroaches and the like, but they generally have a low volatility and have an insecticidal effect, but have a small repellent effect. Further, even if a volatile insecticide or vaporthrin is used alone, the repellent effect is small, and there is a problem that it is difficult to prevent pests from entering the area.
Further, DET is generally used as a pest repellent, but there is a problem that it has no repellent effect in space and has only a repellent effect by contact with a pest, and cannot prevent pest invasion from other than the contact surface. In the above-mentioned patent documents and the like, a description suggesting a space repellent effect can be seen, but a sufficient effect cannot be expected, and a pest repellent that can effectively and reliably achieve pest repellent in a certain space is strong. It was wanted. Others, phthalic acid diesters, 2-ethyl-1,
3-hexanediol and the like are also known, but all of the conventionally known pest repellents have shortcomings such as short duration of effect or few types of applied pests. It was strongly desired.

Therefore, it is an object of the present invention to provide a pest repellent having an excellent space repellent effect which can effectively prevent invasion of various pests in a certain space. Further, an object of the present invention is to provide a pest repellent which is excellent in space repellent effect and contact repellent effect, exhibits a strong pest repellent effect, and is excellent in durability of its efficacy.

[0006]

To achieve the above object, according to the present invention, menthane hydroperoxide, tunyan hydroperoxide, caran hydroperoxide,
Provided is a pest repellent comprising as an active ingredient at least one organic peroxide hydroperoxide selected from the group consisting of bornane hydroperoxide, p-cymene hydroperoxide and cumene hydroperoxide. Further according to the invention, at least 1
It is characterized by containing, as an active ingredient, one kind of organic peroxide hydroperoxide and at least one compound selected from the group consisting of vaporthrin, N, N-diethyl-m-toluamide, perilaldehyde and geraniol. Pest repellents are also provided. In this case, the hydroperoxide is preferably selected from the group consisting of menthane hydroperoxide, pinane hydroperoxide, tyan hydroperoxide, caran hydroperoxide, bornane hydroperoxide, p-cymene hydroperoxide and cumene hydroperoxide. At least one kind is used.

[0007]

Action and Mode of the Invention As described above, insecticides and DE
A preparation containing T as an active ingredient cannot be expected to have a space repellent effect, and it is difficult to prevent invasion of harmful insects such as cockroaches into a specific space. As a result of intensive studies on the correlation between the ecology and habits of various pests and the spatial repellent effect against these pests, the present inventors have found that the volatile terpene-based organic peroxide hydroperoxides, especially the above-mentioned menthane hydroperoxides. A drug containing as an active ingredient at least one organic peroxide hydroperoxide selected from the group consisting of, tanyan hydroperoxide, caran hydroperoxide, bornane hydroperoxide, p-cymene hydroperoxide and cumene hydroperoxide. The present invention has been completed by discovering that it has an excellent repellent action and can effectively prevent the invasion of harmful insects into a certain space. Furthermore, in order to enhance the space repellent action against pests, two or more of the above hydroperoxides can be used in combination.

The present inventors also have found that at least one organic peroxide hydroperoxide and vaporsulin, DE
By using at least one compound selected from the group consisting of T, perillaldehyde and geraniol in combination, a strong repellent action against pests is exhibited by the synergistic effect of these compounds, and a space repellent action and a contact repellent action are provided, It was also found that the repellent effect is excellent in durability. Considering the economic factors and the stability of the drug, the combination with perillaldehyde or geraniol is advantageous. On the other hand, the combination with vaporthrin or DET is particularly effective from the viewpoint of contact repellency and persistence of efficacy. There is (a)
It is particularly effective to use three compounds of the groups (a) to (c) of hydroperoxide, (b) vaporthurin and / or DET, (c) perillaldehyde and / or geraniol in combination. When such an active ingredient is used in combination, the hydroperoxide includes menthane hydroperoxide, pinane hydroperoxide, tunyan hydroperoxide, caran hydroperoxide, bornane hydroperoxide, p-cymene hydroperoxide and cumene hydroperoxide. At least one selected from the group can be used.

The pest repellent of the present invention includes sanitary pests such as cockroaches, for example, German cockroaches, American cockroaches, and American cockroaches, as well as blood-sucking, biting pests and mosquitoes such as mosquitoes, fleas, lice and mites. , It can be effectively used as a repellent against clothing insects such as carp. Therefore, the pest repellent of the present invention is a pest repellent in a home, a kitchen, a cafeteria, a livestock barn, a specific area such as an agricultural / horticultural house, a drawer, a food storage, a costume case, a storage case such as a doll case, and By applying to humans, animals, plants, carpets, etc., it is possible to reliably prevent pests from coming to, approaching, contacting, invading, etc. to these places, and also pests' habitation and feeding damage in the specified area, etc. Etc. and bites of plants and animals,
Blood sucking and the like can be effectively avoided.

In the pest repellent of the present invention, the above-mentioned active ingredient compound can be applied as it is to an area where the pest repellent is required, but it is usually preferable to use an appropriate carrier or other compounding agent in the application area or application. Various forms suitable for the method,
For example, it is used after being prepared into a liquid formulation, a solid formulation and the like. Examples of the carrier used for preparing the liquid form include alcohols such as methyl alcohol and ethyl alcohol, ketones such as acetone and methyl ethyl ketone, ethers such as tetrahydrofuran and dioxane, hexane, kerosene, paraffin and petroleum benzine. And aliphatic hydrocarbons, aromatic hydrocarbons such as benzene and toluene, esters such as ethyl acetate, and halogenated hydrocarbons such as dichloroethane.

The pest repellent of the present invention in the form of a liquid is a coating film forming agent, emulsifier, dispersant, spreader,
Wetting agents, stabilizers, additives such as propellants, for example, cellulose derivatives such as nitrocellulose, acetylcellulose, acetylbutyrylcellulose, methylcellulose, vinyl resins such as vinyl acetate resin, alkyd resins, ethylene vinyl acetate resin, urea. Resin, epoxy resin, polyester resin, urethane resin, silicon resin,
Acrylic resin, chlorinated rubber, coating agents such as polyvinyl alcohol, soaps, polyoxyethylene fatty alcohol ethers such as polyoxyethylene oleyl ether, polyoxyethylene alkyl allyl ethers such as polyoxyethylene nonylphenyl ether, polyoxy Ethylene fatty acid ester, fatty acid glyceride, sorbitan fatty acid ester, sulfuric acid ester of higher alcohol,
Surfactants such as alkylallyl sulfonates such as sodium dodecylbenzene sulfonate, propellants such as liquefied petroleum gas, dimethyl ether and fluorocarbon, casein,
By blending gelatin, alginic acid, CMC and the like, it can be used in various forms such as paint form, adhesive form, emulsion, dispersant, suspension, lotion, cream, spray and aerosol.

[0012] Examples of the carrier used for preparing a solid formulation include silicic acid, kaolin, activated carbon,
Examples thereof include mineral powders such as bentonite, diatomaceous earth, talc, clay, calcium carbonate, and ceramic powder, plant powders such as wood flour, soybean flour, wheat flour, and starch, and inclusion compounds such as cyclodextrin. Further, in preparing the solid dosage form, for example, sublimable carriers such as tricyclodecane, cyclododecane, 2,4,6-triisopropyl-1,3,5-trioxane, trimethylene norbornene and paradichlorobenzene. It is also possible to use a sublimable insect repellent such as Naphthalene, camphor, etc., and melt-mix or pulverize and mix the above-mentioned active ingredient compounds to form a sublimable solid agent. The pest repellent of the present invention is prepared in a microencapsulated form according to, for example, a spray dry method using polyvinyl alcohol, CMC, etc., a liquid curing method using gelatin, polyvinyl alcohol, alginic acid, etc., a coacervation method, etc. You can also do it.

The blending amount of the active ingredient hydroperoxide in the pest repellent composition of the present invention and the applied amount of the repellent may be appropriately determined depending on the dosage form, application method and application site, and are limited. However, the content is usually 1 to 50% by weight. On the other hand, vaporsulin and DE used together with this
T, perillaldehyde and geraniol may be blended in an amount of 0.1 to 3 parts by weight with respect to 1 part by weight of hydroperoxide. Further, the application amount of the pest repellent is, for example, in the case of coating use, the active ingredient compound is preferably about 0.1 mg or more, preferably about 0.5 mg or more per 1 cm ^{2 of the} area to be coated. When used in the form of, application space 1m
^It is suitable to present about 1 g or more of the active ingredient compound per ³ parts.

Further, the pest repellent composition of the present invention comprises
Known pest repellents other than those listed above, efficacy enhancers, antioxidants, insecticides, rodent exterminators and repellents, fungicides, fungicides, herbicides, fertilizers, flavors, colorants Etc. can be blended. Other pest repellents that can be incorporated are 2,3,4,5-bis (Δ ₂ -butylene) -tetrahydrofurfural, di-n-propylisocinchomeronate, di-n-butylsuccinate, 2- Hydroxyethyl octyl sulfide, 2-t-butyl-4
-Hydroxyanisole, 3-t-butyl-4-hydroxyanisole, 1-ethynyl-2-methyl-2-pentenyl 2,2,3,3-tetramethylcyclopropanecarboxylate, 1-ethynyl-2-methyl-2 -Pentenyl 2,2-dimethyl-3- (2 ', 2'-dichlorovinyl) -cyclopropane-1-carboxylate, N-hexyl-3,4-dichloromaleimide and the like can be mentioned.

As the efficacy enhancer, N- (2-ethylhexyl) -bicyclo- [2,2,1] -5-heptene-2,3-dicarboximide, 6- (propylpiperonyl) -butyl is used. Carbityl ether, N- (2-ethylhexyl) -1-isopropyl-4-methylbicyclo [2,2,2] oct-5-ene-2,3-dicarboximide, and the like, and butylhydroxy as an antioxidant. Anisole, dibutylhydroxytoluene, tocopherol, γ-oryzanol and the like, pyrethroids such as general name arethrin and its geometric and / or optical isomers as insecticides, α-naphthylthiourea as rodent control and repellent, Cycloheximide and the like are used as antibacterial and antifungal agents such as salicylic acid, benzoic acid, sorbic acid and p-chloro-m-xylenol. , 2- (4′-thiazoyl) benzimidazole and the like, and the antifungal agent is α-bromocinnamic aldehyde, N-dimethyl-N-phenyl-N′-
(Fluorodichloromethyl) thiosulfamide and the like can be mentioned.

The present invention also provides the above-mentioned pest repellent composition as a substrate, for example, various synthetic resin sheets, animal / vegetable or inorganic fibrous body sheets (paper, cloth, non-woven fabric, leather, etc.), these synthetic resins and inorganic fibers, animals / plants. Mixed sheet with fiber or powder,
Pest repellent obtained by holding a blended cloth or non-woven fabric, a metal foil or film and a laminated sheet of the above various sheets, or a molded product of natural wood or plastic used as a furniture member by an appropriate method such as coating, impregnation, dripping, or kneading. The material can also be used as a film or sheet having a pest repellent property or a furniture member by utilizing the characteristics of the base material.

[0017]

EXAMPLES The present invention will be specifically described below with reference to Examples and Test Examples.

Formulation Example 1 A 2% ethyl alcohol solution of cumene hydroperoxide and a liquefied petroleum gas-dimethyl ether mixture (50: 5)
0) (volume ratio) and mixed in an equal amount and filled in an aerosol can,
The pest repellent of the present invention in the form of an aerosol was obtained.

Formulation Example 2 5 parts by weight of cumene hydroperoxide and 3 of tocopherol
Part by weight is adjusted to a 20% solution with ethyl alcohol, and 45 parts by weight of talc are added and mixed to volatilize the ethyl alcohol. Furthermore, 45 parts by weight of sodium sulfate and 2 parts by weight of silicic acid anhydride were added and mixed sufficiently to obtain a pest repellent of the present invention in the form of powder.

Formulation Example 3 Menthane hydroperoxide (20 parts by weight) and JIS No. 1 kerosene (78 parts by weight) are mixed and stirred, heated to 80 ° C. and added with 2 parts by weight of castor-cured fatty acid. After cooling to room temperature, a pest repellent of the present invention in the form of gel was obtained.

Test Example 1 A cube of 8 × 8 × 8 cm is made from cardboard, and a small box with a 2 × 2 cm window opened vertically from the bottom and a ceiling portion opened is prepared as a passage for cockroaches. Paper (7.5 x 7.5) with a prescribed amount of medicine applied to this small box.
2 x 2 cm) (2 x 2 cm in the center of cm)
Laid out so that the windows of the
(20 cm) in a water drinker 5 cmφ × 2 cm. At the center of the bottom of the small box, a 2 cmφ × 2 cm plastic container containing solid feed is placed. 50 German cockroaches were left free in the costume case, and the feeding amount of the solid feed was measured to evaluate the cockroach repellent effect. Table 1 shows the results obtained using various hydroperoxides as drugs and DET and vaporthrin alone for comparison.

[Table 1] From the results shown in Table 1, although DET and vaporthrin have low repellent effect against cockroaches, hydroperoxide,
In particular, it can be seen that cumene hydroperoxide has an excellent repellent effect (contact repellent and space repellent) and has a long duration of efficacy.

Test Example 2 A cube of 8 × 8 × 8 cm was made from cardboard, a 2 × 2 cm window was opened vertically from the bottom side as a passage for cockroaches, and two small boxes with a sealed ceiling were prepared.
A piece of paper (7.
5 x 7.5 cm) with a pin, and a costume case (65 x 4)
(0 × 20 cm) and the water drinker 5 cmφ × 2 cm is placed as a center so as to face one small box. In one small box, a paper roll coated with vaporthrin was set as a control. At the center of the bottom of the small box, a 2 cmφ × 2 cm plastic container containing solid feed is placed.
In the costume case, 50 German cockroaches were left free and the food intake of the solid feed was measured to evaluate the cockroach space repellent effect. Table 2 shows the results obtained using various hydroperoxides as drugs and DET and vaporthrin alone for comparison.

[Table 2] From the results shown in Table 2, it can be seen that DET and vaporthrin have a low space-repelling effect on cockroaches, but hydroperoxides, particularly cumene hydroperoxide, have a good space-repelling effect and have a long duration of effect.

Test Example 3 Using the mixture of various compounds shown in Table 3 as a drug, the cockroach repellent efficacy was tested in the same manner as in Test Example 1 above. In addition, a paper box coated with 5 mg of vaporthulin was set in one small box serving as a control. The results are shown in Table 3.

[Table 3] From the results shown in Table 3, it can be seen that the combined use of various compounds produces a synergistic effect of the space repellent effect and the contact repellent effect, and further enhances the cockroach repellent effect.

Test Example 4 In a space having an air flow of 1 m / sec, a basket of 10 × 30 × 10 cm was made by using 14 mesh nylon stitches, and 50 adults of Culex tritaeniorhynchus were left free.
The side is surrounded by corrugated cardboard, and the top and bottom are opened, and a petri dish of 8.5 cmφ × 2 cm is placed on the left and right below the lower stitch. The other was used as a blank, and the other was used as a sample, and a 7 cmφ paper impregnated with a predetermined amount was laid in a petri dish, and the repellent effect by the movement of mosquitoes in the nylon stitch was tested. The distribution status of mosquitoes was observed 20 minutes after setting the sample, and the repellent efficiency was calculated. The results are shown in Table 4.

[Table 4] From the results shown in Table 4, it is understood that the pest repellent of the present invention exhibits an excellent repellent effect against blood sucking and biting pests such as mosquitoes.

Test Example 5 Plastic petri dish (bottom surface 7.5φ to lid surface 9.5φ ×
The bottom of a 5.0 cm, converted volume of 277 cm ³ ) is covered with paper, 10 larvae of squid are placed, a 5.0 cmφ wool cloth is placed, and the lid is closed. After 2-3 days, it is confirmed that the larvae of squid damage the wool cloth, and then the drug is added. The drug is No. Cut 5A paper into 7 × 8 cm and draw a line in a 1 cm mesh. 7x8cm paper was coated with ethanol solution of certain chemicals, air-dried for 1 hour, then 1cm ² , 2cm ² , 3
cm ^2, 4cm ^2, from the cut in such a way that 5cm ² to evaluate the clothes moth repellent effect from the loss of wool cloth of every age put in a clothes moth larvae plastic petri dish described above. The results are shown in Table 5.

[Table 5] The results shown in Table 5 show that the pest repellent of the present invention has an excellent repellent effect against clothing pests such as mussels.

[0026]

INDUSTRIAL APPLICABILITY As described above, the pest repellent of the present invention is
Containing, as an active ingredient, at least one organic peroxide hydroperoxide selected from the group consisting of menthane hydroperoxide, tunyan hydroperoxide, karan hydroperoxide, bornane hydroperoxide, p-cymene hydroperoxide and cumene hydroperoxide. Since it is a thing, it is excellent in space repellent action and can effectively prevent pest invasion into a certain space. Further, at least one organic peroxide hydroperoxide and at least one compound selected from the group consisting of vaporthrin, N, N-diethyl-m-toluamide, perilaldehyde and geraniol are contained as active ingredients. As a result, a synergistic effect of these compounds exhibits a strong repellent action against pests, has a space repellent action and a contact repellent action, and is also excellent in the persistence of the repellent effect. Therefore, the pest repellent of the present invention is a cockroach,
Protects the living environment from various hygiene pests such as mosquitoes, fleas, lice, mites, mosquitoes, blood-sucking and biting pests, clothing pests, is useful for epidemics, and contributes greatly to improving the working environment. Is.

Claims (3)

[Claims] 1. At least one organic peroxide hydroperoxide selected from the group consisting of menthane hydroperoxide, tunyan hydroperoxide, caran hydroperoxide, bornane hydroperoxide, p-cymene hydroperoxide and cumene hydroperoxide. A pest repellent which is contained as an active ingredient. 2. At least one organic peroxide hydroperoxide and vaporsulin, N, N-diethyl-m.
-A pest repellent characterized by containing at least one compound selected from the group consisting of toluamide, perilaldehyde and geraniol as an active ingredient. 3. The hydroperoxide is at least one selected from the group consisting of menthane hydroperoxide, pinane hydroperoxide, tyan hydroperoxide, caran hydroperoxide, bornane hydroperoxide, p-cymene hydroperoxide and cumene hydroperoxide. The pest repellent according to claim 2, which is present.