JPH069599B2 - Droplet distribution chip - Google Patents

Droplet distribution chip

Info

Publication number
JPH069599B2
JPH069599B2 JP2234650A JP23465090A JPH069599B2 JP H069599 B2 JPH069599 B2 JP H069599B2 JP 2234650 A JP2234650 A JP 2234650A JP 23465090 A JP23465090 A JP 23465090A JP H069599 B2 JPH069599 B2 JP H069599B2
Authority
JP
Japan
Prior art keywords
orifice
eye drop
chip
droplet distribution
distribution chip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2234650A
Other languages
Japanese (ja)
Other versions
JPH03111052A (en
Inventor
ブニン レオニド
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPH03111052A publication Critical patent/JPH03111052A/en
Publication of JPH069599B2 publication Critical patent/JPH069599B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00Closures with filling and discharging, or with discharging, devices
    • B65D47/04Closures with discharging devices other than pumps
    • B65D47/06Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/18Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers

Description

【発明の詳細な説明】 本発明は主に眼病用の薬剤を分配するために使用する従
来の薬剤スポイト(dropper)に対して有用な点眼チップ
(dropper tip)の新規な設計に関する。
DETAILED DESCRIPTION OF THE INVENTION The present invention is an eye drop tip useful for conventional drug droppers primarily used to dispense drugs for eye diseases.
Regarding new design of (dropper tip).

第1図には、点眼チップ1及びスクィーズボトル2から
構成される従来の眼病用薬剤の放出(delivery)システム
が示されている。このシステムは、滴下方法により均一
な所定の大きさの液滴で薬剤を放出することが意図され
ている。液滴の大きさは、スクィーズボトル2からの流
量を制限する、約0.150mm(約0.06インチ)の直径を有
する、点眼チップ1中のまっすぐな放出流路4の最初に
形作られている、小径の流路3により与えられる液圧の
抵抗によって制御される。この従来の薬剤放出システム
は一般に予定した目的に役立つものであるが、多くの患
者のやり方で常に個々の液滴になるとは必らず、むしろ
液体の流れとなり、その結果として、薬剤の損失とな
り、さらには衣類及び他の布類を汚すことであろう。
FIG. 1 shows a conventional drug delivery system for eye diseases, which is composed of an eyedrop chip 1 and a squeeze bottle 2. This system is intended to release the drug in uniform, sized droplets by the dripping method. The droplet size is a small diameter formed at the beginning of a straight discharge channel 4 in the eye drop tip 1 having a diameter of about 0.150 mm (about 0.06 inch) that limits the flow rate from the squeeze bottle 2. It is controlled by the resistance of the hydraulic pressure provided by the flow path 3. While this conventional drug delivery system generally serves its intended purpose, it does not always result in individual droplets in many patient fashions, but rather a liquid flow, resulting in drug loss. , And even stain clothing and other fabrics.

さらに、狭い流路3を持つ従来の点眼チップは、低開発
国においては容易に利用できない複雑な技術を必要とす
る射出成形技術により、一般にプラスチック類から二次
加工される。
Furthermore, conventional eyedrops with narrow channels 3 are generally fabricated from plastics by injection molding techniques that require complex techniques that are not readily available in underdeveloped countries.

本発明によって、より良い放出制御をもたらす点眼チッ
プが提供され、これは製作のためにより低い水準の技術
しか必要とせず、それ故単一装置についてのコストを低
減させ、、又世界中どこでも実際に製作を可能にするも
のである。
The present invention provides eyedrop tips that provide better controlled release, which requires lower levels of technology for fabrication, thus reducing the cost for a single device, and practically anywhere in the world. It enables production.

これらの利点は第2図に示すチップ5の設計により達成
される。第2図では放出流路6に対する入口は狭い流路
によるものではなく、放出流路と同心ではなく、しかも
ハブ8の側面で放出流路に対してある角度をもって、好
ましくは直角に位置しているオリフィス7により与えら
れている。
These advantages are achieved by the design of chip 5 shown in FIG. In FIG. 2, the inlet to the discharge channel 6 is not a narrow channel, is not concentric with the discharge channel, and is positioned at an angle to the side of the hub 8 with respect to the discharge channel, preferably at a right angle. Is provided by an orifice 7.

本発明の新規なチップにおいて、流れ又は液圧の抵抗
は、製作が困難な狭い流路によって制限されるのではな
く、容器を押しつぶすことにより与えられる、内部の静
的エネルギーを液体の流れの運動エネルギーへ変換する
ことを防ぐ放出流路に液体が入った時、液体の流れの方
向を変換せしめる複雑な放出流路により部分的に制限さ
れる。
In the novel tip of the present invention, the flow or hydraulic resistance is not limited by the narrow channels, which are difficult to fabricate, but the internal static energy provided by crushing the container causes the movement of the liquid flow. When liquid enters the discharge channel that prevents it from being converted to energy, it is partially limited by the complex discharge channel that changes the direction of flow of the liquid.

さらに、オリフィスの断面は円形、三角形、半円形、不
規則形又は矩形等のどの様な形状でも良く、好ましくは
矩形が良く、その場合、液体放出に対する液圧の抵抗
は、矩形の寸法によって部分的に決定される。長く、か
つ、狭い矩形のオリフィスは、同じ断面積の正方形オリ
フィスよりも大きな液圧の抵抗を与える。形状にかかわ
らず、オリフィスは約0.015〜0.02mm2の範囲の断面積を
有している。
Further, the cross-section of the orifice may be any shape such as circular, triangular, semi-circular, irregular or rectangular, preferably rectangular, in which case the hydraulic resistance to liquid discharge depends in part on the dimensions of the rectangle. To be decided. Long and narrow rectangular orifices provide greater hydraulic resistance than square orifices of the same cross-sectional area. Regardless of shape, the orifice has a cross sectional area in the range of about 0.015 to 0.02 mm 2 .

オリフィス7の大きさと形状は所望の仕様の範囲内で単
純化した成型技術により制限され得る。
The size and shape of the orifice 7 can be limited by simplified molding techniques within desired specifications.

【図面の簡単な説明】[Brief description of drawings]

第1図は、従来の眼病用薬剤の放出システムを示す断面
図である。 第2A図は、本発明による薬剤の放出システムの点眼チ
ップを示す断面図であり、第2B図は、第2A図の2B
−2B線に沿って切断した横断面図である。 〔主要部分の符号の説明〕 1……点眼チップ 2……スクィーズボトル 3……小径の流路 4……放出流路 5……点眼チップ 6……放出流路 7……オリフィス 8……ハブ。
FIG. 1 is a sectional view showing a conventional drug delivery system for eye diseases. 2A is a cross-sectional view showing an eye drop tip of the drug delivery system according to the present invention, and FIG.
FIG. 2B is a transverse cross-sectional view taken along line -2B. [Explanation of symbols of main parts] 1 ... Eye drop chip 2 ... Squeeze bottle 3 ... Small diameter flow path 4 ... Ejection flow path 5 ... Eye drop chip 6 ... Emission flow path 7 ... Orifice 8 ... Hub .

Claims (3)

【特許請求の範囲】[Claims] 【請求項1】放出流路への入口が、放出流路と同心でな
いオリフィスによって与えられることを特徴とする制御
された眼病用薬剤放出のための点眼チップ。
1. An eye drop tip for controlled ophthalmic drug release, wherein the inlet to the release channel is provided by an orifice that is not concentric with the release channel.
【請求項2】オリフィスが約0.015〜0.02mm2の断面積を
有する請求項1記載の点眼チップ。
2. The eye drop tip according to claim 1, wherein the orifice has a cross-sectional area of about 0.015 to 0.02 mm 2 .
【請求項3】オリフィスの断面が非円形である請求項2
記載の点眼チップ。
3. The orifice has a non-circular cross section.
The described eye drop chip.
JP2234650A 1989-09-08 1990-09-06 Droplet distribution chip Expired - Lifetime JPH069599B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40454089A 1989-09-08 1989-09-08
US404,540 1989-09-08

Publications (2)

Publication Number Publication Date
JPH03111052A JPH03111052A (en) 1991-05-10
JPH069599B2 true JPH069599B2 (en) 1994-02-09

Family

ID=23600011

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2234650A Expired - Lifetime JPH069599B2 (en) 1989-09-08 1990-09-06 Droplet distribution chip

Country Status (4)

Country Link
EP (1) EP0416694B1 (en)
JP (1) JPH069599B2 (en)
CA (1) CA2024673A1 (en)
DE (1) DE69010597T2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0720997U (en) * 1993-09-21 1995-04-18 山崎産業株式会社 Western style handrail device

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6098852A (en) * 1999-01-27 2000-08-08 Automatic Liquid Packaging, Inc. Tip for liquid drop dispensing container
JP3922910B2 (en) 2001-10-31 2007-05-30 参天製薬株式会社 Eye drops container with stepped part
AU2002358549A1 (en) * 2001-11-30 2003-06-10 Crown Cork And Seal Technologies Corporation A closure
CA2616392A1 (en) * 2007-12-21 2009-06-21 Pharmascience Inc. Pharmaceutical delivery device
WO2019027025A1 (en) 2017-08-04 2019-02-07 クラレノリタケデンタル株式会社 Member for discharging liquid and container
JP7066134B2 (en) * 2017-08-04 2022-05-13 クラレノリタケデンタル株式会社 Liquid pouring materials and containers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2834520A (en) * 1956-06-15 1958-05-13 Nyden Robert Spouts for containers
GB874952A (en) * 1960-05-30 1961-08-16 Anchor Glass Company Ltd A dropper device
EP0222944A1 (en) * 1985-11-07 1987-05-27 Delford O. Dougherty Drop dispenser
DE3735909A1 (en) * 1987-10-23 1989-05-03 Hansen Bernd DRIP BOTTLE AND METHOD FOR THEIR PRODUCTION
EP0378935B1 (en) * 1988-12-20 1992-09-23 Societe Technique De Pulverisation (S.T.E.P.) Device to dispense a liquid or cream in droplets having small volumes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0720997U (en) * 1993-09-21 1995-04-18 山崎産業株式会社 Western style handrail device

Also Published As

Publication number Publication date
DE69010597T2 (en) 1995-01-26
CA2024673A1 (en) 1991-03-09
EP0416694B1 (en) 1994-07-13
EP0416694A1 (en) 1991-03-13
JPH03111052A (en) 1991-05-10
DE69010597D1 (en) 1994-08-18

Similar Documents

Publication Publication Date Title
US5931386A (en) Spray nozzle having an oblong atomizer
KR20090087917A (en) Metered drop bottle for dispensing microliter amounts of a liquid in the form of a drop
DE102008042116B4 (en) Valve for atomizing fluid
EP1368245B1 (en) Drop cap for dosing the amount of liquid in a drop and container comprising a drop lid
CA2436011C (en) Liquid ejection head
US20170333922A1 (en) Low cost impinging jet nozzle
US6715697B2 (en) Device for dispensing a fluid product and method of dispensing a fluid product
CA2011734A1 (en) Liquid droplet dispensing apparatus
EP0703739B1 (en) Aerosol-foam dispenser head
JPH069599B2 (en) Droplet distribution chip
EP1475157A1 (en) Nozzle for nasal sprayer having a plurality of exit orifices for spraying viscous material
AU689918B2 (en) Non-streaming ophthalmic tip and delivery device
DE2127964C3 (en) Valve actuation button for pressurized gas packs
DE112017002334T5 (en) Fluidic sampling nozzle and spray nozzle applying the same
US20130161417A1 (en) Push-Button For A System For Dispensing A Product Under Pressure
JPH0784224B2 (en) Cap and liquid dispensing device for dispensing liquid from a container
EP3858303A1 (en) A dispenser for dispensing liquids
US5356052A (en) BFS metered drop bottle
KR20220129647A (en) Nozzles for dispensing liquids in the form of mists
DE19917093A1 (en) Aerosol applicator, in particular, for liquid medicaments comprises micropump which sucks liquid from its container and delivers it into atomizing nozzle that points into atomizing chamber
DE102022102476B3 (en) Drop dispenser for dispensing a pharmaceutical liquid
IT9019559A1 (en) FOAM FORMING DEVICE FOR FOAMING LIQUID PROJECTION GUNS
JP6976469B1 (en) Eye drop container
JPH05246475A (en) Nozzle of aerosol device
JP5596315B2 (en) Nozzle of aerosol device