JPH0690971A - Production of bone implant - Google Patents
Production of bone implantInfo
- Publication number
- JPH0690971A JPH0690971A JP34794091A JP34794091A JPH0690971A JP H0690971 A JPH0690971 A JP H0690971A JP 34794091 A JP34794091 A JP 34794091A JP 34794091 A JP34794091 A JP 34794091A JP H0690971 A JPH0690971 A JP H0690971A
- Authority
- JP
- Japan
- Prior art keywords
- filling mold
- filling
- mold
- bone implant
- porous material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 22
- 239000007943 implant Substances 0.000 title claims abstract description 19
- 238000004519 manufacturing process Methods 0.000 title claims description 11
- 239000000843 powder Substances 0.000 claims abstract description 20
- 239000011230 binding agent Substances 0.000 claims abstract description 16
- 238000000034 method Methods 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 12
- 239000011148 porous material Substances 0.000 claims abstract description 9
- 239000011347 resin Substances 0.000 claims abstract description 8
- 229920005989 resin Polymers 0.000 claims abstract description 8
- 238000005245 sintering Methods 0.000 claims abstract description 8
- 150000001875 compounds Chemical class 0.000 claims description 7
- 229910052602 gypsum Inorganic materials 0.000 claims description 6
- 239000010440 gypsum Substances 0.000 claims description 6
- 229910052751 metal Inorganic materials 0.000 claims description 6
- 239000002184 metal Substances 0.000 claims description 6
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 claims description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 4
- 239000012298 atmosphere Substances 0.000 claims description 3
- 239000000919 ceramic Substances 0.000 claims description 3
- 230000000630 rising effect Effects 0.000 claims description 3
- 238000010521 absorption reaction Methods 0.000 claims description 2
- 229910052786 argon Inorganic materials 0.000 claims description 2
- 239000011521 glass Substances 0.000 claims description 2
- 229910052757 nitrogen Inorganic materials 0.000 claims description 2
- 230000001590 oxidative effect Effects 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 238000005979 thermal decomposition reaction Methods 0.000 claims description 2
- 238000000465 moulding Methods 0.000 abstract description 5
- 238000002156 mixing Methods 0.000 abstract description 2
- 239000000463 material Substances 0.000 description 7
- 239000002245 particle Substances 0.000 description 5
- 238000005452 bending Methods 0.000 description 4
- 229910052720 vanadium Inorganic materials 0.000 description 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 229940125904 compound 1 Drugs 0.000 description 2
- 210000004394 hip joint Anatomy 0.000 description 2
- 230000000399 orthopedic effect Effects 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 229910019590 Cr-N Inorganic materials 0.000 description 1
- 229910019588 Cr—N Inorganic materials 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 235000010407 ammonium alginate Nutrition 0.000 description 1
- KPGABFJTMYCRHJ-YZOKENDUSA-N ammonium alginate Chemical compound [NH4+].[NH4+].O1[C@@H](C([O-])=O)[C@@H](OC)[C@H](O)[C@H](O)[C@@H]1O[C@@H]1[C@@H](C([O-])=O)O[C@@H](O)[C@@H](O)[C@H]1O KPGABFJTMYCRHJ-YZOKENDUSA-N 0.000 description 1
- 239000000728 ammonium alginate Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000012300 argon atmosphere Substances 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 229940125782 compound 2 Drugs 0.000 description 1
- 230000001054 cortical effect Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 210000003275 diaphysis Anatomy 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000005242 forging Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 230000008407 joint function Effects 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000013585 weight reducing agent Substances 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/006—Pressing and sintering powders, granules or fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
- B29C43/04—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles using movable moulds
- B29C2043/043—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles using movable moulds rotating on their own axis without linear displacement
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/7532—Artificial members, protheses
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Prostheses (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は整形外科治療において人
体内に埋め込まれる骨インプラントの製造方法に関す
る。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for manufacturing a bone implant to be implanted in the human body in orthopedic treatment.
【０００２】[0002]
【従来の技術】人体の関節に変形、欠損、壊死等が生じ
た場合に関節を補綴して関節機能を再建するための人工
関節（特にその人工骨頭側のステム部）や、骨幹部の骨
折の場合の骨髄内釘治療に用いる髄内釘等、整形外科治
療において人体内に埋め込まれる骨インプラントは、ス
テンレスＳＵＳ３１６Ｌ、Ｃｏ−Ｃｒ、Ｃｏ−Ｃｒ−Ｎ
ｉ、Ｔｉ−６％Ａｌ−４％Ｖ等の金属インプラント材を
利用して、鋳造、鍛造、焼結等の適宜手段によって形成
されるのが主流であった。2. Description of the Related Art Artificial joints (particularly, the stem portion on the side of the artificial femur) and fractures of the diaphysis for repairing the joint function by prosthesing the joint when the human body is deformed, missing, or necrotic. Bone implants to be implanted in the human body during orthopedic treatment, such as intramedullary nails used for intramedullary nail treatment in the case of, are made of stainless steel SUS316L, Co-Cr, Co-Cr-N.
i, Ti-6% Al-4% V, etc. were mainly used, and formed by appropriate means such as casting, forging, and sintering.
【０００３】[0003]
【発明が解決しようとする課題】ところが、金属インプ
ラント材を利用した骨インプラントには様々な問題があ
り、例えば、人の皮質骨の曲げ弾性率はおよそ１６ＧＰ
ａであるのに対し、ステンレスＳＵＳ３１６Ｌ、Ｃｏ−
Ｃｒ、Ｔｉ−６％Ａｌ−４％Ｖの曲げ弾性率はそれぞれ
２００、２１３、１２４ＧＰａであって、骨の約８〜１
３倍もあるため、人工関節がたわんだり、ねじれたりす
ることによって局所的に応力が集中し、その応力集中部
分で骨を破壊してしまう虞れがある。However, bone implants using metal implant materials have various problems. For example, the bending elastic modulus of human cortical bone is about 16 GP.
a, stainless steel SUS316L, Co-
The bending elastic moduli of Cr and Ti-6% Al-4% V are 200, 213 and 124 GPa, respectively, which is about 8 to 1 of bone.
Since it is three times as large, stress may be locally concentrated due to bending or twisting of the artificial joint, and the bone may be destroyed at the stress concentrated portion.
【０００４】また、アクリルベースのセメントを用いず
に直接インプラントと骨を固着するセメントレス人工股
関節の臨床において、骨髄腔と良く嵌合して体重や歩行
等の運動による応力の作用を繰り返し受けるステム先端
部では骨の増勢がみられるが、応力が作用しない部分で
は骨への刺激がなくなるために逆に骨組織の吸収が起こ
って骨量が減少するという結果が報告されている。則
ち、応力が作用しない部分においては、骨と人工関節と
の嵌合にズレや緩みが増長され、人工関節を安定して保
持することができなくなる虞れがある。Further, in the clinical practice of a cementless artificial hip joint in which an implant and bone are directly fixed to each other without using an acrylic-based cement, a stem that is well fitted with a bone marrow cavity and is repeatedly subjected to stress due to exercise such as weight and walking. It has been reported that the bone mass is reduced in the tip part, but bone is resorbed in the part where stress is not applied and the bone is not stimulated in the part where the stress is not applied, so that the bone mass is decreased. That is, in a portion where no stress is applied, displacement or looseness is increased in fitting of the bone and the artificial joint, and there is a possibility that the artificial joint cannot be stably held.
【０００５】また、比重の大きな金属インプラント材に
よる人工関節は、患者にとって挿入中の負担が大きいと
いう問題がある。Further, the artificial joint made of a metal implant material having a large specific gravity has a problem that the burden on the patient during insertion is large.
【０００６】金属インプラント材による人工関節におい
て、曲げ弾性率を減少させて生体骨のそれに近似させ、
かつ軽量化する目的で、人工関節のステム部を中空にす
ることが提案されている（特開平１−１４８２５４号公
報）。しかし、この発明では、中空とされたステム部の
内部空間は、一部分開放されて外部と連通するようにな
っているため、ステム部の内部空間に大量の出血した血
液やその他の体液が貯留し、患部の治癒を遅延させ、ま
た細菌の繁殖による感染が生じるという欠点がある。In an artificial joint using a metal implant material, the bending elastic modulus is reduced to approximate that of living bone,
In addition, for the purpose of weight reduction, it has been proposed to hollow the stem portion of the artificial joint (Japanese Patent Laid-Open No. 1-148254). However, in the present invention, the hollow internal space of the stem portion is partially opened to communicate with the outside, so that a large amount of bleeding blood or other body fluid is stored in the internal space of the stem portion. However, there are drawbacks that the healing of the affected part is delayed and infection is caused by the propagation of bacteria.
【０００７】したがって、閉状態の中空部、則ち外部と
連通しない中空部を有するステム部とすることが望まれ
る。Therefore, it is desired to use a stem portion having a closed hollow portion, that is, a hollow portion that does not communicate with the outside.
【０００８】このような閉状態の中空部を有するステム
部は、金属やセラミックの粉体とバインダーとからなる
コンパウンドを成形型内に充填して粉体焼結を行う際
に、形成すべき中空部に対応する形状の中子を成形型内
に配置することによって、製造することが可能である。The stem portion having a hollow portion in such a closed state is a hollow portion to be formed when powder is sintered by filling a molding die with a compound consisting of powder of metal or ceramic and a binder. It is possible to manufacture by arranging a core having a shape corresponding to the part in the molding die.
【０００９】しかしながら、このような方法によるとき
は、焼結後、例えば薬品での洗浄により中子を溶解除去
し、更に、中子の支持棒が挿通された孔を溶接等の適宜
手段により封止しなければならず、製造工程が複雑とな
ってしまう。However, in the case of such a method, after sintering, the core is dissolved and removed by, for example, washing with a chemical, and the hole in which the support rod of the core is inserted is sealed by an appropriate means such as welding. It must be stopped, which complicates the manufacturing process.
【００１０】本発明は、上記従来技術の問題点に鑑み
て、閉状態の中空部を有する骨インプラントを効率的に
製造することのできる新規な方法を提供することを目的
とする。In view of the above problems of the prior art, it is an object of the present invention to provide a novel method capable of efficiently manufacturing a bone implant having a hollow portion in a closed state.
【００１１】[0011]
【課題を解決するための手段】上記目的を達成するため
に創案された本発明による骨インプラントの製造方法
は、多孔質材料よりなる充填型に、この充填型のゲート
口より、原料粉末と樹脂バインダーとを混合したコンパ
ウンドを充填し、充填型のゲート口を封止した後、充填
型に所要の運動を与えることにより、コンパウンドにお
ける樹脂バインダーのうちの相当量を充填型の多孔質材
料に吸収除去せしめ、その後、成形体を充填型から取り
出して、この成形体を所定温度にて脱バインダー処理
し、更に粉体焼結を行って、樹脂バインダーの吸収除去
量に相当する閉状態の中空部を有する焼結体を得ること
を特徴とする。The method for manufacturing a bone implant according to the present invention, which was conceived to achieve the above object, comprises a filling die made of a porous material, a raw material powder and a resin from a gate opening of the filling die. After filling the compound mixed with the binder and sealing the gate opening of the filling die, by giving the required movement to the filling die, a considerable amount of the resin binder in the compound is absorbed by the filling type porous material. After that, the molded body is taken out of the filling mold, the molded body is debindered at a predetermined temperature, and further, powder sintering is performed to obtain a hollow portion in a closed state corresponding to the absorption and removal amount of the resin binder. It is characterized by obtaining a sintered body having.
【００１２】原料粉末としては、任意の金属材料やセラ
ミックス材料を選択して用いることができ、複数の材料
を混合した混合原料粉末としても良い。As the raw material powder, any metal material or ceramic material can be selected and used, and a mixed raw material powder obtained by mixing a plurality of materials may be used.
【００１３】充填型は、ガラスフリット、焼結金属、石
膏または多孔性セラミックス等の多孔質材料よりなる。The filling mold is made of a porous material such as glass frit, sintered metal, gypsum or porous ceramics.
【００１４】成形後の脱バインダー処理は、溶媒または
熱分解法により、大気または窒素あるいはアルゴン中に
て、毎時３〜１００℃の昇温速度にて３００〜７００℃
の温度範囲で行うことができる。The debinding process after molding is carried out by a solvent or a thermal decomposition method in the air, nitrogen or argon at a temperature rising rate of 3 to 100 ° C. per hour at 300 to 700 ° C.
Can be performed in the temperature range of.
【００１５】粉体焼結は、真空や水素等の非酸化性雰囲
気にて、１０００〜１４００℃の温度範囲で行うことが
できる。The powder sintering can be performed in a temperature range of 1000 to 1400 ° C. in a non-oxidizing atmosphere such as vacuum or hydrogen.
【００１６】充填型の運動は、一般に、充填型を収容固
定する筒状ホルダーを回転および／または揺動すること
によって与えることができる。この際の運動は適宜プロ
グラムすることができ、その運動方向および／または速
度を調整し、同一条件の運動を繰り返し、あるいは異な
る条件の運動を組み合わせることによって、中空成形体
を均一な層厚を有するものとし、あるいは部分的に偏肉
を有するものとすることができる。The movement of the filling mold can be generally given by rotating and / or rocking a cylindrical holder for housing and fixing the filling mold. The movement at this time can be programmed appropriately, and by adjusting the movement direction and / or speed, repeating the movement under the same conditions, or combining the movements under different conditions, the hollow molded article can have a uniform layer thickness. It can be made to have a partial thickness unevenness.
【００１７】[0017]
【実施例】粒径４５μｍ以下のチタン微粉末と、粒径４
５μ以下のアルミニウム６０ｗｔ％−バナジウム４０ｗ
ｔ％の母合金粉末とを、重量比で９：１として機械的に
混合し、得られたＴｉ−６ｗｔ％Ａｌ−４ｗｔ％Ｖの混
合粉を原料粉末として用いる。EXAMPLE Titanium fine powder having a particle size of 45 μm or less, and a particle size of 4
Aluminum less than 5μ 60wt% -vanadium 40w
Mechanically mixed with t% of mother alloy powder at a weight ratio of 9: 1, and the obtained mixed powder of Ti-6 wt% Al-4 wt% V is used as a raw material powder.
【００１８】バインダーとしてはアルギン酸アンモニウ
ム１％水溶液を用い、上記原料粉末と混練して、粘度１
５００〜２０００ｃｐのコンパウンドを調製する。A 1% aqueous solution of ammonium alginate was used as a binder, and the raw material powder was kneaded to obtain a viscosity of 1
Prepare 500-2000 cp compound.
【００１９】このコンパウンド１を、図１に示すよう
に、特級石膏を使用した分割可能な筒状充填型２（図
２）にそのゲート口３より注入し、キャビティー内に完
全に充填した後、ゲート口３を、充填型２と同一材料で
ある特級石膏よりなる栓４にて密封する。As shown in FIG. 1, this compound 1 was poured into a separable cylindrical filling mold 2 (FIG. 2) using a special grade gypsum through its gate port 3 to completely fill the cavity. The gate opening 3 is sealed with a plug 4 made of special grade gypsum which is the same material as the filling mold 2.
【００２０】次に、この充填型２を筒状ホルダー５に固
定状態に収納し、モータ６により筒状ホルダー５をその
軸心のまわりに遠心力が働くよう５０〜３００ｒｐｍの
速度で回転させ（図３）、更に、サーボモータ７により
１８０°の角度範囲に亙って筒状ホルダー５を交互に逆
方向に揺動させる（図４）。これによって、充填型２の
キャビティー内の粒子には図５に示すような動きが与え
られる。Next, the filling mold 2 is housed in a cylindrical holder 5 in a fixed state, and the cylindrical holder 5 is rotated by a motor 6 at a speed of 50 to 300 rpm so that a centrifugal force is exerted around its axis ( 3) Furthermore, the cylindrical holder 5 is alternately swung in the opposite direction by the servomotor 7 over an angle range of 180 ° (FIG. 4). As a result, the particles in the cavity of the filling mold 2 are caused to move as shown in FIG.
【００２１】充填型２のキャビティー内に充填された状
態のコンパウンド１においては、原料粉末同志の間に
は、付着力、凝集力、バインダーの浮力等の様々な力が
働いているが、これらの力に比べて原料粉末の粒子に働
く重力が十分に大きければ、粒子は力学的に最も安定な
状態に並ぼうとする。In the compound 1 in the state of being filled in the cavity of the filling mold 2, various forces such as adhesive force, cohesive force, and buoyancy of the binder work between the raw material powders. If the gravitational force acting on the particles of the raw material powder is sufficiently larger than the force of, the particles tend to be in the most mechanically stable state.
【００２２】しかしながら、前記した筒状ホルダー５の
回転運動による遠心力が働き、原料粉末は充填型２のキ
ャビティー内周面に均一に押しつけられ、同時に相当量
のバインダーが型２を形成する石膏材料の無数の小孔内
に吸収除去される。However, due to the centrifugal force generated by the rotational movement of the cylindrical holder 5 described above, the raw material powder is uniformly pressed against the inner peripheral surface of the cavity of the filling mold 2, and at the same time, a considerable amount of binder forms the gypsum 2. It is absorbed and removed in the myriad of small pores in the material.
【００２３】かくして、静止後の充填型２においてキャ
ビティー内に成形される成形体８は、図６に示すよう
に、石膏材料の小孔内に吸収除去されたバインダー分に
相当する閉状態の中空部９が形成されている。Thus, as shown in FIG. 6, the molded body 8 molded in the cavity of the stationary filling mold 2 is in a closed state corresponding to the binder component absorbed and removed in the small holes of the gypsum material. A hollow portion 9 is formed.
【００２４】このような成形体８を、充填型２を分割し
て取り出した後、アルゴン雰囲気中で毎時５０℃の昇温
速度で７００℃まで上げ、この温度に３時間保持して脱
バインダー処理し、次に真空中（１×１０−５ｔｏｒ
ｒ）で１３００℃にて３時間焼結することにより、閉状
態の中空部を有し、しかも外殻部の相対密度が９５％と
高密度の、チタン製の人工股関節ステム部が製造され
る。After such a molded body 8 was taken out by dividing the filling mold 2, the temperature was raised to 700 ° C. at a temperature rising rate of 50 ° C./hour in an argon atmosphere, and this temperature was maintained for 3 hours to remove the binder. Then, in vacuum (1 × 10 −5 torr)
Sintering at 1300 ° C. for 3 hours under r) produces a titanium artificial hip joint stem portion having a closed hollow portion and a high relative density of the outer shell portion of 95%. .
【００２５】[0025]
【発明の効果】本発明方法によれば、外部と連通しない
閉状態の中空部を有する骨インプラントを効率的に製造
することができる。本発明方法は遠心力を利用して中空
部を形成するので、原料粉末が型内キャビティーの内周
面に高密度に集中するため、成形体の外殻部は高密度高
強度に形成される。According to the method of the present invention, it is possible to efficiently manufacture a bone implant having a closed hollow portion that does not communicate with the outside. In the method of the present invention, the hollow portion is formed by utilizing the centrifugal force, so that the raw material powder is concentrated on the inner peripheral surface of the in-mold cavity at a high density, so that the outer shell portion of the molded body is formed with high density and high strength. It
【図１】本発明方法の一実施例に用いられる充填型およ
びそのキャビティー内の充填コンパウンドを示す縦断面
図である。FIG. 1 is a longitudinal sectional view showing a filling mold used in an embodiment of the method of the present invention and a filling compound in a cavity thereof.
【図２】図１の充填型を示す斜視図である。FIG. 2 is a perspective view showing the filling mold of FIG.
【図３】図１の充填型を回転揺動させるための装置構成
例を示す平面図である。FIG. 3 is a plan view showing a device configuration example for rotating and rocking the filling mold of FIG.
【図４】図３の装置構成例を示す正面図である。FIG. 4 is a front view showing an example of the apparatus configuration of FIG.
【図５】回転揺動される充填型内の原料粉体の動きを示
す説明図である。FIG. 5 is an explanatory view showing the movement of the raw material powder in the filling mold that is rotationally rocked.
【図６】回転揺動後の静止状態の充填型およびそのキャ
ビティー内の成形体を示す縦断面図である。FIG. 6 is a vertical cross-sectional view showing a stationary filling mold after rotation and rocking and a molded body in its cavity.
１ コンパウンド ２ 充填型 ３ ゲート口 ４ 栓 ５ 筒状ホルダー ６ モータ ７ サーボモータ ８ 成形体 ９ 閉状態の中空部 1 Compound 2 Filling Type 3 Gate Port 4 Plug 5 Cylindrical Holder 6 Motor 7 Servo Motor 8 Molded Body 9 Closed Hollow Portion
───────────────────────────────────────────────────── フロントページの続き (72)発明者 曽我石 一郎 東京都中央区京橋３丁目１番１号 蛇の目 ミシン工業株式会社内 (72)発明者 片倉 健男 神奈川県足柄上郡中井町井ノ口1500番地 テルモ株式会社内 (72)発明者 大澤 孝明 神奈川県足柄上郡中井町井ノ口1500番地 テルモ株式会社内 (72)発明者 上田 義久 神奈川県足柄上郡中井町井ノ口1500番地 テルモ株式会社内 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Ichiro Soga 3-1-1 Kyobashi, Chuo-ku, Tokyo Within Jamme Sewing Machinery Co., Ltd. (72) Inventor Takaaki Osawa 1500 Inoguchi, Nakai-cho, Ashigarashami-gun, Kanagawa Terumo Co., Ltd. (72) Inventor Yoshihisa Ueda 1500 Inoguchi, Nakai-cho, Ashigarakami-gun, Kanagawa Terumo Corporation
Claims (4)
填型のゲート口より、原料粉末と樹脂バインダーとを混
合したコンパウンドを充填し、前記充填型のゲート口を
封止した後、前記充填型に所要の運動を与えることによ
り、前記コンパウンドにおける前記樹脂バインダーの相
当量を前記充填型の多孔質材料に吸収除去せしめ、その
後、成形体を前記充填型から取り出して、この成形体を
所定温度にて脱バインダー処理し、更に粉体焼結を行っ
て、前記樹脂バインダーの吸収除去量に相当する閉状態
の中空部を有する焼結体を得ることを特徴とする骨イン
プラントの製造方法。1. A filling mold made of a porous material is filled with a compound in which a raw material powder and a resin binder are mixed through the gate opening of the filling mold, the gate opening of the filling mold is sealed, and then the filling is performed. By applying a required motion to the mold, a considerable amount of the resin binder in the compound is absorbed and removed by the porous material of the filling mold, and then the molded product is taken out of the filling mold and the molded product is heated to a predetermined temperature. The method for producing a bone implant, wherein the binder is debindered in step 1, and further powder sintering is performed to obtain a sintered body having a hollow portion in a closed state corresponding to the absorption and removal amount of the resin binder.
リット、焼結金属、石膏または多孔性セラミックスのい
ずれかよりなることを特徴とする、請求項１の骨インプ
ラントの製造方法。2. The method for manufacturing a bone implant according to claim 1, wherein the filling-type porous material is made of glass frit, sintered metal, gypsum or porous ceramics.
熱分解法により、大気または窒素あるいはアルゴン中に
て、毎時３〜１００℃の昇温速度にて３００〜７００℃
の温度範囲で行うことを特徴とする、請求項１の骨イン
プラントの製造方法。3. The debindering treatment is carried out by a solvent or a thermal decomposition method in the atmosphere or in nitrogen or argon at a temperature rising rate of 3 to 100 ° C. per hour at 300 to 700 ° C.
The method for producing a bone implant according to claim 1, wherein the method is performed in the temperature range of.
て、１０００〜１４００℃の温度範囲で行うことを特徴
とする、請求項１の骨インプラントの製造方法。4. The method for producing a bone implant according to claim 1, wherein the powder sintering is performed in a temperature range of 1000 to 1400 ° C. in a non-oxidizing atmosphere.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34794091A JPH0690971A (en) | 1991-12-03 | 1991-12-03 | Production of bone implant |
| EP19920311060 EP0545718A3 (en) | 1991-12-03 | 1992-12-03 | Method of making bone-implants |
| US07/985,833 US5336465A (en) | 1991-12-03 | 1992-12-03 | Method of making bone-implants |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34794091A JPH0690971A (en) | 1991-12-03 | 1991-12-03 | Production of bone implant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0690971A true JPH0690971A (en) | 1994-04-05 |
Family
ID=18393639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP34794091A Pending JPH0690971A (en) | 1991-12-03 | 1991-12-03 | Production of bone implant |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0690971A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008503317A (en) * | 2004-06-22 | 2008-02-07 | ボーン サポート アクチボラゲット | Curing substance manufacturing equipment |
| WO2011080953A1 (en) | 2009-12-28 | 2011-07-07 | ナカシマメディカル株式会社 | Shock absorbing structure and method of manufacturing same |
-
1991
- 1991-12-03 JP JP34794091A patent/JPH0690971A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008503317A (en) * | 2004-06-22 | 2008-02-07 | ボーン サポート アクチボラゲット | Curing substance manufacturing equipment |
| JP4891900B2 (en) * | 2004-06-22 | 2012-03-07 | ボーン サポート アクチボラゲット | Curing substance manufacturing equipment |
| WO2011080953A1 (en) | 2009-12-28 | 2011-07-07 | ナカシマメディカル株式会社 | Shock absorbing structure and method of manufacturing same |
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