JPH06500324A - Pest control formulations - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed description of the invention] Pest control formulations The present invention provides formulations, particularly two incompatible pesticidal agents (Pe5ticide). Pest control formulations containing ), methods of manufacturing such formulations and pest control Concerning its use in extermination.

Anhydrous formulations of pest control agents, i.e. formulations that do not contain an aqueous phase, are It has been found that it can be formulated with a second immiscible phase containing a pesticide. This is It has the advantage that compatible pest control agents can be incorporated into the same formulation.

Thus, the present invention provides a two-phase formulation, the first phase of which contains a first active ingredient, a stable and optional emulsifiers or wetting or dispersing agents for the first active ingredient. a second carrier or solvent, the second phase comprising a second active ingredient and optionally a second active ingredient; an emulsifying agent or wetting or dispersing agent and a carrier or solvent for the second active ingredient. A two-phase formulation is provided.

Typically, the first active ingredient is dissolved or dispersed in the first phase, but the active ingredient is liquid. No solvent is always required when The second phase is immiscible with the first phase. a second active ingredient dissolved or dispersed therein. Preferably the first phase is water and non-aqueous. A miscible phase, the second phase is an aqueous phase.

The first active ingredient and the second active ingredient are preferably inseparable when contained in a single phase. Physically and/or chemically incompatible. i.e. one of the active ingredients in the formulation The presence of one usually has an adverse effect on the stability or usefulness of the other active ingredient. difference Furthermore, the active ingredient in the first phase has e.g. irritating properties or harmful vapors. , which may give rise to can be avoided more easily. However, in the past, active ingredients were stable but irritating. Although it may have been possible to produce a formulation with Irritation such as can be avoided. Here, active ingredients are biologically active ingredients. It shall mean both non-active compounds and biologically active compounds. for example , active ingredients include insecticides, acaricides, herbicides, fungicides, insect and plant growth regulators, pheromones, insect behavior modifiers, biological inhibitors (e.g. viruses, bacteria and eggs), dyes, fragrances, flavoring agents, bactericides, lubricants, drugs, food supplements, paints, Polishing agents, lacquers (including hair lacquers), fiber processing agents (including sizing agents), or whose use is limited due to incompatibility with other active ingredients. selected from among other active ingredients. Examples of incompatible active ingredients include Pedicides (insecticides, acaricides), herbicides, fungicides, or insect or plant growth regulation combinations of pesticidal agents selected from: incompatible pests Examples of insecticides include pyrethroids and organophosphate insecticides, pyrethroids and hormonal insecticides. Muamidine insecticides, α-cyanopyrethroid insecticides, and thiazole anthelmintics , pyrethroid and tributyltin fungicides.

Examples of pyrethroid insecticides include the following formula (I) (where R is the following formula Or the following formula (In these groups, n is 0 or 1, R1 is halo, CF, or CHF, O, R2 is hydrogen or halo, and Z and Zl are halo, CF, and selected from methyl, xl is hydrogen or halo, and X is H, CN or (j CH) ) or the following formula or the following formula Examples of pyrethroids are (IR3)-cis, trans-3-(2,2-dichlorovinyl)-2,2- 3-phenoxybenzyl dimethylcyclopropane-1-carboxylate (vermesri) ), (IR3)-cis, trans-3-(2,2-dichlorovinyl)-2 , 2-dimethylcyclopropane-1-carboxylic acid (R3)-α-cyano-3-ph Enoxybenzyl (cypermethrin) and its individual isomers, e.g. t4f ( l RS) -c i s isomer (alphamethrin), (I R) -c i 5-3-(2,2-dibromvinyl)-2,2-dimethylcyclopropane-1 -carboxylic acid (S)-α-cyano 3-phenoxybenzyl (deltamethrin), ' or about a 2:3 pair of two enantiomers, (IR)-cis-3-(2,2- dichlorvinyl)-2,2-dimethylcyclopropanecarboxylic acid (S)-α-cy Ano-3-phenoxybenzyl and (IS)-ci 5-3-(2,2 -dichlorvinyl)-2,2-dimethylcyclopropanecarboxylic acid (R)-α- Cyano-3-phenoxybenzyl was converted into (IR)-trans-3-(2,2-dichloro lorvinyl)-2,2-dimethylcyclopropanecarboxylic acid (S)-α-cyano -3-phenoxybenzyl and (I5)-trans-3-(2,2-dichloro rubinyl)-2,2-dimethylcyclopropanecarboxylic acid (R)-α-cyano- Reaction mixture containing with 3-phenoxybenzyl (Beeta Cybermethrin) , (Z)-(IRS)-cis-3(2-chloro-3,3,3-trifluoro propenyl)-2,2-dimethylcyclopropanecarboxylic acid (RS)-〇-sia Nor 3-phenoxybenzyl (cyhalothrin) and its (S)(Z)-(IR )-cis isomer and (R)(Z)-(is)-cis isomer mixture; (R5)-2-(4-chlorophenyl)-3-methylbutyric acid (RS)-α-cyano -3-phenoxybenzyl (fenvalerate) and single (S), (S) isomer (nisphene valerate), (S)-2-(4-difluoromethoxyphenyl) -3-Methylbutyric acid (RS) -〇-cyano-3-phenoxybenzyl (Fluparine N-(2-chloro-α,α,α-trifluoro-p-tolyl)-D-ba Phosphoric acid (R5)-α-cyano-3-phenoxybenzyl (fluparinate), ( IRS)-c is, trans-3-(2,2-dichlorovinyl)-2, 2-dimethylcyclopropanecarboxylic acid (RS)-α-cyano-4-fluoro- 3-phenoxybenzyl (cyfulswan), (IR3)-cis, trans -3-(2-chloro-2-(4-chlorophenyl)vinyl)-2,2-dimethyl Cyclopropanecarboxylic acid (RS)-α-cyano-4-fluoro-3-phenoxylate Sibenzil (flumethrin), (Z)-(IRS, 3RS)-3-(2-chlor -3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopro 2-methylbiphenyl-3-ylmethyl pancarboxylate (bifuenthrin); Allethrin, e.g. (IR,3R)-2,2-dimethyl-3-(2-methyl- 1-propenyl)cyclopropanecarboxylic acid (IR3)-3-allyl-2-methy -4-oxo-2-cyclopentenyl (bioallethrin), (IR,3R)- 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarbo (IS)-3-allyl-2-methyl-4-oxo-2-cyclopentenyl ( S-bioallethrin) and a mixture of allethrin isomers (nisbioallethrin): Resmethrin, for example (IR5,3RS; IRS.

3SR)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopro 5-benzyl-3-furylmethyl pancarboxylate (resmethrin) and (IR, 3R)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropyl 5-benzyl-3-furylmethyl carboxylate (Bioresmethone) It is.

An example of an organophosphate insecticide is 0.0-dimethyl- 2-pyridyl) phosphorothioate (chlorpyrifosmethyl).

An example of a formamidine insecticide is N-methylbis(2,4-xylylamide). methyl)amine (amitrazo). Examples of thiazole anthelmintics are 2,3 , 5.6-tetrahydro-6-phenylimidazo[2,1-b]thiazole Examples of fungicides include tributyltin oxide.

Particularly preferred examples of incompatible active ingredients in the formulations of the invention include: Contains lutamethrin and chlorpyrifos-methyl.

Preferably, the first phase is dispersed in the second phase. a first phase in which a stabilizer is dispersed; Forms a barrier at the interface between the second phase and the second phase. The stabilizer preferably has film-forming properties alkanols, for example aqueous solutions as described in EP 331 474; It is an alkanol that can act as an evaporation retardant in spray systems. I like this or a primary alcohol, preferably methyl, ethyl or trifluoromethane. At most 1 selected from chil and halo (e.g. fluoro or chloro) or having two side chain substituents, such substituents being separated from the alcohol group preferably (up to 7 carbon atoms away from the hydroxyl group) (preferably), and furthermore, the alkanol is fully (preferably unsubstituted, and preferably C+s to Cta, preferably saturated, and further at 27°C. Preferably, it is a solid. For example, octadecane-1-ol, especially hexadecan-1-ol, Can-1-ol is preferred, hexadecane-1-ol (cetyl alcohol and Usually a small proportion of octadecane-1-ol (stearyl alcohol) is present. These “ketostearyl alcohols” are available on the market as a mixture with Cole' is quite satisfactory; heptadecan-1-ol works well, but Very expensive. Other highly effective film formers include 1-hexadecy 1-heptadecylamine and 1-octadecylamine. So Next preferred film forming agents are hexadecane-2-ol and 1,2-hexane. Sadecanediol, methyl acetate, stearyl acetate, methyl palmitate and 1. There is 2-octadecanediol. N-alkoxyalkanolamine and alcohol xyalkanol, e.g. CHs(CHi)x+Oc*H40H, CHs(CH z)z+0csHaOH, CH3(CHI)+70c:2H40H or CHi (CHi) + 5OcJ401 (can also be used, as well as oxyethylene docosano and any mixtures of these film-forming compounds can also be used.

The emulsifier can be any suitable compound or mixture of compounds. cationic milk Adhesives can be used, but these tend to irritate the user's eyes. Dodecylbene Calcium sulfate (CDBS) or sodium α-isopropylnaphthalene sulfonate Anionic emulsifiers such as thorium (SDNS) can also be used, but these is not as effective in stabilizing the emulsion but retains evaporation retardation. hold Preferably, the emulsifier has an HLB of 6 to 20, preferably 8 to 18 (parental non-ionic compounds or mixtures of non-ionic compounds with a woody/oleophilic balance) It is a thing. Suitable compounds include polyoxyethylene stearyl ether (PSE ), polyoxyethylene monolaurate (PEM), polyoxyethylene monolaurate (PEM) oleate (PMO), sorbitan monooleate (SMO), nonylphenol ethoxylate (NPE), polyethylene glycol (PEG) and oleyl Blend of ethoxyle-1-(10 mol) and PEG20 glyceryl oleate (OE/PGO) is included.

These emulsifiers are available as follows.

No. 1 Pencil 4 Ll! OE/PGO Tego Plant Th Goldschmidt MII PSE Br1j72, Br1j76 I CI Specialty Ke Brij7 g Michals Co., Ltd. PEM Tween 20 ICI Specialty Chemicals SMO Span 80 I CI Subesharity Chemicals Co., Ltd. PMO Tween 80 ICI Specialty Chemicals NPE ethylane run:・Chemicals Company KE0.55. BV CDBS Acrylan CA Run:・Chemicals Company SDN Aerosol O3 Shea The solvent for the Namid GB second phase preferably has a low relative molecular weight, i.e. about 2 It has a molecular weight of 0.00. Suitable compounds include aromatic hydrocarbons, lower alkyl esters, lower ketones, lower alkanols and lower alkanes. Here, for The term "lower" refers to C1 to Cat, preferably C3 to CI6, more preferably C , -C.

Specific solvents include the following, all of which are available from Exxon Chemicals. Available.

"Tsurpetz 150": Aromatic hydrocarbon solvent (C ,~C1,), "Tsurpetz 200": aromatic charcoal with a boiling point range of 226 to 290°C Hydrogenide solvent (C,.~Cl2), "Exa-door 00": Hebutyl acetate 99% Purity and colorless kerosene = paraffins and naphthenes in the distillation range of 180-270°C Any mixture of high boiling non-aromatic hydrocarbons.

The first phase contains one or more active ingredients (optionally considered as active ingredients for the purposes of the formula below). one or more solvents, one or more emulsifiers and (along with synergists or enhancers) or) contains one or more stabilizers along with other ingredients such as fragrances and dyes. It's fine.

From a preferred standpoint, the first phase of the formulation has the following formula: where L is 15 or less. Therefore, A is 700376, B is -1,51, and C is Q, 8472. where Mo is the weight average relative molecular weight of the oil phase and M is the average molecular weight of the stabilizer. , X is (Mo)''/Y, where Y is the minimum number of moles of the oil phase that dissolves the stabilizer. is the molar solubility ratio of the formulation, defined as the number of moles of the formulation) satisfy. However, in the above equation, any solvent that does not have a liquid phase at 27°C Excluded.

"Oil phase" is a liquid, non-aqueous phase that contains one or more active ingredients, their solvent and in some cases In some cases, it contains an emulsifier.

To avoid confusion, in the above formula, the relational symbol ≦ indicates “less than or equal to”, and “ "Exp" is the exponent of (continued in angle brackets), and "1n" is the natural logarithm, i.e. lo gs, L is divided by 4, X is a power of B, and B is a negative value (-1, 5 1), and in the definition of X, Mo is a power of 1.8.

Preferably L is 12.10 or less than 8, most preferably 5 or less.

Distilled water sprays have an "L" value of about 26, and most common dilute formulations have an "L" value of about 22- It has a value of 30.

In the formulations of the present invention, "L" is the desired ratio for calculating the required ratio of ingredients. Can be set to a value.

Mo, the average molecular weight of the oil phase, is the weight average, i.e. the relative proportions of the components are considered. considered.

The value "Y", i.e. the molar solubility ratio of the formulation, is the molar solubility ratio of oil to alkanol in various ratios. Make a series of mixtures, cool these mixtures to 27°C, and cool the cold mixtures at 27°C. The amount of oil required to completely dissolve a given amount (mol) of retardant by leaving it for at least 48 hours. It can be derived experimentally by determining the amount of phase (in moles). the former to the latter Y is given by dividing.

Preferred film-forming compounds include C+a to C such as hexadecane-1-ol. Includes 2° saturated alkanols and CIll to C18 saturated amines.

Preferred emulsifiers and solvents for the first phase are disclosed in EP 331 474 (which is incorporated herein by reference) That's right.

The uses of the formulations of the invention depend on the nature of the active ingredients contained within the formulation; control the infestation of harmful organisms such as pests, mites, parasites or microbial infestations commonly used for The dosage of the active ingredient is customarily applied for the specific application. corresponding to the application amount of these active ingredients when used.

A preferred formulation of the invention is 20% chlorpyrifos-methyl and 1% deltamethyl. Contains surin and cetyl alcohol is a stabilizer. This formulation is grain-like Useful in treating stored crops to protect them from pests.

Insect pests include, in particular, Coleoptera (e.g., Anobium). ), Ceuthorrhynchus, Rhynchophorus ( Rhynchophorus), Cosmopolites s), Li5sorhoptrus, Meligates ligethes), Hybotenemus (Hyp.

thenemus), Hylesinus (Hylesinus), Akarinma ( Acalymma), Lema, Psylliod es), Leptinotarsa, Gonocephalum (G onocephalum), Agriotes, delmore Vida (Dermolepida), Heteronych (Heteronych) us), Phaedon, Tribolium ), Sitophilus, Oryzaephilus ephilus), Rhyzopertha, Prostef Prostephanus, Crypt.

1etes), h Trogoderma, Typhieae (T ypheae), Diabrotica, Antonomas (Anthonomus) or Anthrenus (Anthrenus 5pp) ), Plioptera (e.g. Ephestia, Ma mestra), Nearias, Vectinophora (Pect) inophora), Ostrinia (Ostrinia), Trichobrusia ( Trichoplusia), Pieris, Plo dia), SitOtrOga, Corcilla ((:orcyr a), Laphygma, Agrotis ), Amathes, Wiseana, ) Tryporyza, Diatraea, Sparganothis, Cydia, Archips, Plutella, Chiro ( Chilo), Heliosis (H61iothis), Spodobutella litora Squirrel (Spodoptera littoralis), Herlotwiss veile Sense (Helrotuis virescens), Subodobutella (5p odoptera) or Tineola (Tineola spp)), Diptera Eyes (e.g. Musca, Aedes, Anophele) Anopheles, Culex, Prosina (G lossina), Simulium, St. omoxys), Haematobia, Tabanas anus), Hydrotaea *Lucilia lia), ChrysoIIlyia, Calitroga (C allitroga), Dermatobia, gastello Ga5terophilus, Hypoderma ), Hylemyia, Atherigona ), Chlor.

ps) + Phyto@yza, Cerati tis), Lirio+myza, Melophagus (Me lophagus 5pp)), Phyllophuterales (Mall ophaga) (for example, Damalina 5pp)), Lamiformes (e.g. Linognathus, Haematovinus) (Haematopinus 5pp)), Hemiptera (e.g. (f, Anois ( Aphis), Pemisia (Be+aisia), Phorodon (Phor odon), Aeneolamia, Emboasca (EI) llpoasca), Parkinsiella, Virilla (Pyrilla), Aonidiella, Kotskas (Coccus), Pseudococcus, Herope Helopeltis, Lygus, Desdercus (Dy5dercus), Oxycarenus, Zara (Nezara), Aleyrodes (Aleyrodes), Triad? (Triatoma), Psylla, Myzus ), Megoura, phylloxera ), Adelges, Ni1apar vata), Nephotettix, or Cymex (Cimex spp)), Orthoptera (e.g. Get', Locusta) sta), Gryllus, Cyst Cell Power (5chist) ocerca) or Acheta (5pp)), Hymenoptera (e.g. , BlatteLla, Be1) Periplane ta) or Blatta (5pp)), Hymenoptera (e.g. Athalia, Cephus, Atta ), 5olenopsis or Monomolyrum oriua + 5pp)), Isoptera (e.g. Odontotermes totermes), Reticulitermes (5) pp)), Microptera (e.g. Ctenocephalides) des) or Pulex spp)), the order Pulex (e.g. Lepismaspp), Hymenoptera (e.g. Forficula spp) eripsocus 5pp)), Hymenoptera (e.g. Grylus tabaci (T. Contains hrips tabaci)).

Pests of ticks include ticks, many genera such as Booph illus), Ornithodorus, Ribicepha Rhipicephalus AmblyomIIla ), Hyaloma, Ixodes, He Haemaphysalis, Derm acentor), Anocentor, Might and Manges, such as Acarus, Tyroff Tyrophagus, Glycyphagus ), Tetranychus, Psoro ptes), Notoednes), Sarcobides (5a rcoptes), Sorerganas (Psorergates), Corio Chorioptes, Eutrombicula la), Demodex, Panonych us), Bryobia, Er1oph yes), Blaniulus, Polyphagotarsone Trout (Polyphagotarsonemus), Scu tigerella), Oniscus spp., Peribra Periplaneta, Blatta, Blatta Blattella) and Lapisma.

Formulations of the invention can be manufactured as follows.

(1) The first active ingredient is dissolved in a solvent to form the first phase or is itself a first phase. It is phase.

(2) Dissolve the stabilizer in the first phase.

(3) Dispersing the second active ingredient in a portion of the second phase.

(4) Disperse the surfactant in the first phase or in the portion of the second phase containing the second active ingredient. let

(5) The first phase is then dispersed into a portion of the second phase that does not contain the second active ingredient. .

(6) the remainder of the second phase containing the second active ingredient is added to the first phase and the other portion of the second phase; Mix with a mixture of.

Step (6) is not performed under high shear conditions. Therefore, the second part of the second phase is It only mixes with the first part of the second phase and the resultant The first phase is a dispersion or emulsion in phase.

The present invention will now be explained in detail with reference to the following examples. Example 1 is pyrethroids and organic phosphorus 1 illustrates a formulation according to the invention containing a pesticide-based insecticide. Example 2 is a formulation according to the invention We present test results to demonstrate the stability of Example 3 is biological treatment for various pests. The results of the test are shown.

Example 2: Ward 1 ■ Soni Lee Chlorpyrifos methyl 19.15 Tsurupetstu 150 19.15 Water (deionized) 51.40 Emulsifier 2.00 Deltamethrin (20%SC) 5.20 Deltamethrin (20%SC) Deltamethrin (20%) in water with surfactants, thickeners and biological preservatives Contains.

Add cetyl alcohol to a solution of chlorpyrifos-methyl dissolved in Tsurpetz 150. The oil phase was prepared by melting the liquid at temperatures up to 50°C.

Emulsifier was added to water at 60’C and the resulting aqueous solution was cooled to 50°C (aqueous phase) .

The above oil phase was added to the aqueous phase at 50°C with vigorous mixing and the resulting emulsion was The solution was cooled to 20°C.

A 20% aqueous suspension of deltamethrin was added with stirring at 2Q-25°C.

Five Uni Eiji 11 Each activity in the formulation according to the invention (A) and the two-phase formulation without stabilizers (B) The stability of the ingredients was tested.

A's A chlorpyrifos methyl/deltamethrin formulation containing a film forming agent was prepared as in Example 1 above. Manufactured in a similar manner.

Typical stability data: Chlorpyrifos methyl (CPME) test (value ±10% ) va M 25℃ 38℃ 50'C Initial 100 100 100 3M or 4M 101 103 1036M 102 100 103 12M 101 94 101 Typical stability data: Deltamethrin (DLTM) at 311" low 25" ℃　38℃　50℃　Initial　100　100　100 3M or 4M 96 99 98 6M 97 103 103 12M 98 94 76 B's Chlorpyrifos methyl/deltamethrin formulation without film formers Typical stability data: CPME Time 8M 25℃ 38℃ 50℃ Initial 100 100 100 3M 112 106 71 Typical stability data: Deltamethrin (DLTM) 1/10 LL at 25°C 38℃ 50℃ initial 100 100 100 3M 75 75 1 These results indicate that formulation (B) without film-forming agent is relatively unstable. show.

Takumi Uni! 11 dishes x1 Experimental procedure 2 The formulation, appropriately diluted with water, was prepared at Uniil in Victoria for 400 min. Sprayed tons of grain.

The formulation was applied to a rotating stream of grain at a spray rate of 1 liter per ton. . The treated grains were sampled at predetermined intervals using a vacuum blower. 150 or 300 The bioassay was carried out by maintaining 100 adult pests on 10 g of grain. 25℃ After 3 weeks of incubation at 55-60% relative humidity, the pests were sieved and mortality determined. was counted. Furthermore, the grain was screened and removed at 7.9 and 11 weeks, and the mortality rate, The number of adult progeny was counted.

StopMLu50 100 0 6 99.8oryzae L, 5 10 0 0 0 1003 100 0 0 to.

4.5 100 0 0 100 9 100 0 0 to.

Rhyzopereha 0 100 0 0 100dom100do 15 100 0 0 1004.5 100 0 0 100 0TriboLLu　O100001100cascaneu　1.5　100 0], 99.74.5 100 OL 99.5 6 100 0 4 99.0 Queens 1and O100001100TriboL1u 15 10 0 0 2 97cas neum 3 99 0 0 100279 4. 5 99 0 1 99.76 100 0 499.0 0ryzaephilus O10000100surinao+ensis 1.5 100 0 0 1003 100 0 2 99.7 4.5 99 0 0 100 6 95 0 1 99.9 The above results demonstrate that pests are well controlled for up to 9 months of post-treatment storage. It shows.

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Claims (10)

[Claims] 1. Pest control formulations consisting of a two-phase formulation, the first phase of which is the first active. stabilizers, and optional emulsifiers or wetting or dispersing agents and the first a carrier or solvent for the active ingredient, the second phase containing the second active ingredient; an optional emulsifier or wetting or dispersing agent and a carrier for the second active ingredient; Pest control formulations, such as those consisting of chemicals or solvents. 2. Pest control formulation according to claim 1, wherein the first phase is a water-immiscible phase. . 3. 3. A pesticidal formulation according to claim 2, wherein the second phase is an aqueous phase. 4. When the first active ingredient and the second active ingredient are contained in a single phase, ) The pest control agent according to any one of claims 1 to 3, which is chemically incompatible. formulation. 5. Claims where the incompatible active ingredients include a pyrethroid and an organophosphate insecticide 4. The formulation for controlling pests according to item 4. 6. Claims where the pesticides are deltamethrin and chlorpyrifos-methyl in an aqueous system. A pest control formulation according to scope 5. 7. The first phase of the formulation is Mass of oil phase/mass of stabilizer ≦M0/M5XExp[In(L/4)+Cln(A XB)/C] (where L is 15 or less, A is 700376, and B is - 1.51, C is 0.8472, and Mo is the weight average relative molecular weight of the oil phase. , Ms is the average molecular weight of the stabilizer, X is (Mo)1.6/Y, and Y is , defined as the minimum number of moles of oil phase that dissolves the stabilizer divided by the number of moles of stabilizer is the molar solubility ratio of the formulation) (However, in the above equation, any solvent that does not have a liquid phase at 27°C Pest control formulation according to any one of claims 1 to 6 (excluded). 8. 8. The pest control formulation according to claim 7, wherein L is 5 or less. 9. The stabilizer is a C16-C20 saturated alkanol or a C16-C20 saturated amine. The pest control formulation according to claim 7 or 8. 10. Control pest infestations such as pests, mites, parasites or microbial infestations The pest control formulation according to any one of claims 1 to 9 is used to Method.