JPH0644551U - Outer cylinder for container and syringe - Google Patents

Abstract

(57) [Abstract] [Purpose] Compared with the conventional outer cylinder for a syringe that also serves as a container, it is possible to prevent accidental movement of the stopper and to greatly reduce the risk of damage or damage to the glass cartridge. (EN) Provided is an outer cylinder for a container / syringe which can be used. [Structure] A glass cartridge 120 is fitted and locked to a cylindrical body 110 made of synthetic resin having a projection 115 for finger stop. A synthetic resin tube tip 140 having an injection needle attachment portion 143 and a through hole 145 is connected to the tubular body 110. By this connection, the rubber stopper 130 that closes the one end 122 of the glass cartridge 120 is compressed and sandwiched between the glass cartridge 120 and the barrel tip 140, and the glass is housed in the holder 150 formed by the tubular body 110 and the needle base 140. Cartridge 120 and stopper 13
Holds 0 and.

Description

[Detailed description of the device]

[0001]

[Industrial applications]

 The present invention relates to an outer cylinder for a container / syringe in which a predetermined amount of drug is sealed in a sterile state in advance.

[0002]

[Prior art]

 In the container / syringe 1 shown in FIG. 4 which is known from Japanese Patent Publication No. 62-58745, an outer cylinder 5 is formed from a synthetic resin barrel tip 2, a synthetic resin finger grip 3 and a glass cartridge 4. After a predetermined amount of the medicine 8 is filled and sealed between the rubber stopper 6 and the rubber plunger 7 in the glass cartridge 4 of the outer cylinder 5, sterilization treatment such as steam sterilization is performed, A certain amount of drug 8 is shipped in a glass cartridge 4 in an aseptically sealed state.

By the way, in the outer cylinder 5 for the container / syringe 1, the stopper 6 is moved toward the inner chamber 9 of the cylinder tip 2 in a situation described below, so that a part or all of the stopper 6 can be moved. To the inner chamber 9, and there is a risk that the medicine 8 that is hermetically sealed in the glass cartridge 4 will leak from the through hole 11 through the bypass groove 10 and the like, and the risk of losing its sterility. There is a problem of having it. Reference numeral 12 in FIG. 4 indicates a cap for maintaining the sterility of the outer cylinder 5 until the container / syringe 1 is used.

(A) Some chemicals 8 filled and sealed in the glass cartridge 4 expand due to heating at the time of steam sterilization, increase in outside temperature, etc., and the stopper 6 moves toward the inner chamber 9 of the barrel tip 2. Push forward. (B) Some chemicals 8 are filled and sealed in the glass cartridge 4 together with an inert gas for the purpose of preventing changes in components due to heating during steam sterilization. The stopper 6 is expanded by the rise of the temperature and the like, and the stopper 6 is pushed toward the inner chamber 9 of the cylinder tip 2. (C) Vibration generated during transportation of the product is added to the medicine 8 and the stopper 6 is weighted more than expected, and the stopper 6 is moved toward the inner chamber 9 of the barrel tip 2.

In order to reduce the risk, in the outer cylinder used in the container / syringe known in Japanese Patent Publication No. 4-36030, etc., as shown in FIG. By using a glass cartridge 20 around which the stopper 2 is provided, the protrusion 23 and the groove 24 of the stopper 23 are fitted in the concave and convex portions to prevent the stopper 23 from unintentionally moving.

However, since the movement of the stopper 23 cannot be surely prevented even by the method of fitting the concavo-convex portion, the container-combined syringe known in Japanese Utility Model Laid-Open No. 37646/1990, as shown in FIG. The outer cylinder 30 is used in which a rubber packing 34 is sandwiched between the injection needle mounting portion 31 and the barrel tip portion 33 of the glass syringe 32, and the sandwiched state is held by winding aluminum 35 or the like.

Since the outer cylinder 30 can reliably prevent unexpected movement of the packing 35 due to vibration or the like during transportation, as compared with the outer cylinder 5 of FIG. The risk of spillage and loss of sterility can be greatly reduced.

However, since the glass syringe 32 has the barrel tip portion 33, the shape is more complicated and the unit price is higher than that of the glass cartridge 4 of FIG. 4, and the outer barrel 30 is manufactured by winding the aluminum 35 or the like. Due to the troublesome tightening, the outer cylinder 30 has a problem that the manufacturing cost is higher than that of the outer cylinder 5 in FIG.

Further, in the conventional outer cylinders 5 and 30 for a container / syringe shown in FIGS. 4 and 6, since the glass cartridge 4 or the glass syringe 32 is used by being exposed, the conventional outer cylinders 5 and 30 are used. 30 has a problem that the glass cartridge 4 or the glass syringe 32 has a risk of being damaged during transportation of the container / syringe or the like, or of being damaged even if damage is not caused.

When the glass cartridge 4 or the glass syringe 32 is damaged, if the drug to be sealed therein is highly viscous and is injected at a high pressure by an automatic injector or the like, at the time of injection, etc. There is a risk that the scratch will grow at a stretch and the glass cartridge 4 or the glass syringe 32 will be damaged.

[0011]

[Problems to be solved by the device]

 In view of the above-mentioned problems of the prior art, the present invention uses a bottomless cylindrical glass cartridge having a simpler shape than the glass syringe 32 having the cylinder tip portion 33 of FIG. 6 to ensure unexpected movement of the stopper. 4 and FIG. 6, the risk of damage or damage to the glass cartridge is greatly reduced compared to the conventional outer cylinders 5 and 30 for a container / syringe shown in FIGS. It is an object of the present invention to provide an outer cylinder for an injector that also serves as a container.

[0012]

[Means for Solving the Problems]

 As means for solving the above-mentioned problems, in the present invention, a bottomless cylindrical glass cartridge is fitted and locked to a bottomless cylindrical tubular body made of synthetic resin, and is made of synthetic resin with a bottom. A tubular barrel tip is connected to the tubular body, and a rubber stopper that closes one end of the glass cartridge is compressed and held between the barrel tip and the glass cartridge, and the tubular body and the The glass cartridge and the stopper are held inside a holder formed by a barrel tip, and the barrel tip has an injection needle mounting portion projecting from an outer wall surface of its bottom and a central portion of the mounting portion. The tubular body has a through hole extending from the tip to the inner wall surface of the bottom portion, and the cylindrical body has a protrusion for finger-holding on the outer wall surface thereof.

[0013]

[Action]

 In the present invention having the above-described structure, as shown in FIGS. 1 and 2, a bottomless tubular glass cartridge 120 is fitted into a bottomless tubular tubular body 110 made of synthetic resin. A synthetic resin-made bottomed tubular barrel tip 140 is coupled to the tubular body 110, and a rubber stopper closing one end 122 of the glass cartridge 120 is compressed by the barrel tip 140 and the glass cartridge 120. Since it is sandwiched, a repulsive force due to this compression is generated in the stopper 130, and this repulsive force acts on the glass cartridge 120, and the pushing force P acts on the cartridge 120.

However, since the glass cartridge 120 is locked to the tubular body 110, the glass cartridge 120 is not pushed by the pushing force P, and the reaction force R and the pushing force P generated at the locking portion are retained. It is securely held by sandwiching with.

Moreover, in the present invention, since the glass cartridge 120 and the stopper 130 are held inside the holder 150 formed by the tubular body 110 and the tip 140, the glass cartridge 120 is Both are protected by the entire holder 150 without being exposed to the outside of the holder 150.

In the present invention, the barrel tip 140 penetrates the injection needle mounting portion 143 projecting from the outer wall surface 142 of the bottom portion 141 and the tip of the central portion of the mounting portion 143 to the inner wall surface 144 of the bottom portion 141. Since it has the hole 145, as shown in FIG. 3, a predetermined amount of the drug 162 is aseptically sealed between the stopper 130 and the rubber plunger 161 in the glass cartridge 120 before shipment. At a medical site, etc., a plunger rod 163 is attached to the plunger 161, and a double-ended needle (sometimes referred to as a double-edged needle) 164 is attached to the injection needle attachment portion 143 of the barrel tip 140, and the double-ended needle 164 is a penetrating needle. After the 165 is penetrated through the through hole 145 of the barrel tip 140 and the stopper 130, the plunger 161 is pushed through the plunger rod 163. Thereby, the medicine 162 in the glass cartridge 120 can be ejected from the double-ended needle 164.

[0017]

【Example】

 As shown in FIGS. 1 and 2, an embodiment of the present invention is such that a bottomless cylindrical glass cartridge 120 is fitted to a transparent bottomless cylindrical tubular body 110 made of synthetic resin. The first end 121 of the glass cartridge 120 is brought into contact with the locking projection 114 that is provided around the inner peripheral wall surface 113 of the tubular body 110 near the first opening 111, so that the glass cartridge 120 is tubular. A rubber stopper 130, which is locked to the body 110 and has a projecting portion 131 protruding outward in the circumferential direction, is tightly fitted to one end 122 of the glass cartridge 120, which is an edge at this one end 122. The protruding portion 131 of the stopper 130 is compressed and held between the second edge 123 and the bottom portion 141 of the tube tip 140, which will be described later, so that the one end 122 of the glass cartridge 120 is stopped. It is closed at 130.

It should be noted that the tubular body 110 has a protrusion 115 for finger stop on the outer peripheral wall surface 117 near the first opening 111, and the male screw 116 is screwed on the outer peripheral wall surface 117 near the second opening 112. The stopper 130 has a recess 133 that is recessed in the axial direction from the end surface 132 in the glass cartridge 120.

A transparent cylinder bottomed cylinder tip 140 made of a synthetic resin includes an injection needle mounting portion 143 projecting from the outer wall surface 142 of the bottom portion 141, and a central portion of the mounting portion 143 from the tip to the bottom portion 141. There is a through hole 145 reaching the inner wall surface 144, and a female screw 148 is screwed on the inner peripheral wall surface 147 near the opening 146. The female screw 148 is screwed onto the male screw 116 of the tubular body 110. It is made to connect with the cylindrical body 110, and the holder 150 is formed with the cylindrical body 110 by this connection. The glass cartridge 120 and the stopper 130 are held inside the holder 150 and protected by the holder 150.

By the way, in the illustrated embodiment, the first edge 121 of the glass cartridge 120 is brought into contact with the locking projection 114 of the cylindrical body 110, and the glass cartridge 120 is locked to the cylindrical body 110. However, the locking portion of the glass cartridge 120 with the tubular body 110 is not limited to the first edge 121, and the method of locking the glass cartridge 120 and the tubular body 110 is not limited to the illustrated method. .

Therefore, for example, the tubular body 110 has a concave portion or a convex portion on the inner peripheral wall surface 113 thereof, and the glass cartridge 120 has a convex portion or a concave portion on the outer peripheral wall surface 113 thereof. The glass cartridge 120 may be locked to the tubular body 110 by a concave-convex fitting between the concave portion or the convex portion and the convex portion or the concave portion of the glass cartridge 120.

Further, in the illustrated embodiment, a rubber stopper 130 has a projecting portion 131 projecting outward in the circumferential direction, and this stopper 130 is tightly fitted to one end 122 of the glass cartridge 120. The protruding portion 131 of the stopper 130 is compressed and held between the second edge 123 of the glass cartridge 120 and the bottom portion 141 of the barrel tip 140, and the one end 122 of the glass cartridge 120 is closed by the stopper 130.

However, the stopper 130 is not limited to the presence or absence of the protruding portion 131, and the tight fitting to the glass cartridge 120 is not limited. Further, the portion of the barrel tip 140 for compressing and sandwiching the stopper 130 is not limited to the bottom portion 141 thereof, and the portion of the glass cartridge 120 for compressing and sandwiching the stopper 130 is not limited to the second edge 123 thereof. .

Therefore, the portion of the barrel tip 140 where the stopper 130 is compressed and sandwiched may be, for example, a convex portion or the like provided on the inner peripheral wall surface 147 or the inner wall surface 144 of the bottom portion 141, or the glass cartridge 120. The portion of the stopper 130 that compresses and clamps the stopper 130 may be, for example, an inward step portion formed on the inner peripheral wall surface of the one end portion 122.

The stopper 130 is, for example, in the shape of a plate, is not tightly fitted to the glass cartridge 120, is compressed and sandwiched between the second end edge 123 of the glass cartridge 120 and the barrel tip 140, and the glass cartridge 120. One end 122 of the glass cartridge 120 may be closed, or a columnar shape that is closely fitted to the glass cartridge 120 and that has an inwardly facing step formed on the inner peripheral wall surface of the glass cartridge 120 at one end 122 thereof. The end 122 of the glass cartridge 120 may be closed by being compressed and pinched with the barrel tip 140.

However, the stopper 130 has a larger contact area with the glass cartridge 120 when the stopper 130 is tightly fitted to the glass cartridge 120 as in the illustrated embodiment, so that the stopper 130 is more tightly fitted to the glass cartridge 120. It is preferable because the clogging performance becomes large.

Further, in the illustrated embodiment, the stopper 130 has the recess 133 that is recessed from the end surface 132 thereof in the axial direction, but the presence or absence of the recess 133 is not limited in the stopper 130. Therefore, a recessed portion that is recessed in the axial direction from the end surface that is in contact with the bottom portion 141 of the barrel tip 140 may be provided other than the recessed portion 133, or may not be provided at all. .

However, when the stopper 130 has a large thickness, it is better to have a recess such as the recess 133 as compared with the case where the stopper does not have the recess as shown in FIG. When 4 is attached to the injection needle attachment portion 143 of the barrel tip 140, the thickness of the portion of the double-ended needle 164 that is penetrated by the penetrating needle 165 becomes thin, which is preferable because the penetration becomes easy.

Further, in the illustrated embodiment, although the male body 116 of the tubular body 110 and the female thread 148 of the barrel tip 140 are screwed together, the tubular body 110 and the barrel tip 140 are connected to each other. The method of connecting the body 110 and the barrel tip 140 is not limited to the screwing of the male screw 116 and the female screw 148. A method in which fixation is added may be used.

Further, in the illustrated embodiment, the injection needle mounting portion 143 protruding from the outer wall surface 142 of the bottom portion 141 of the barrel tip 140 is a luer lock type, but the injection needle mounting portion 143 is a luer lock type. However, the lure taper type or the like may be used.

Further, in the illustrated embodiment, the tubular body 110 and the tubular tip 140 are made of transparent synthetic resin, but the tubular body 110 and the tubular tip 140 may be made of synthetic resin. Since it is not limited whether or not it has transparency, it may be made of an opaque synthetic resin. However, in the case of the outer cylinder for a container / syringe according to the present invention, it is preferable that the cylindrical body 110 and the tube tip 140 are made of a transparent synthetic resin, as shown in FIG. The presence or absence of the drug 162 and the like can be confirmed from the outside of the outer cylinder when the above is sealed, which is preferable.

[0032]

[Effect of device]

 In the present invention, a bottomless cylindrical glass cartridge is used, and as compared with the glass syringe 32 having the cylinder tip portion 33 shown in FIG.

Further, in the present invention, since the rubber stopper is compressed and sandwiched between the glass cartridge and the tip of the cylinder, it is possible to reliably prevent accidental movement of the stopper as compared with the outer cylinder 5 of FIG. Therefore, there is an effect that the risk of leakage and loss of sterility of a drug that is aseptically sealed in a glass syringe can be significantly reduced.

Further, in the present invention, the glass cartridge is securely held by the pushing force and the reaction force, and a part of the glass cartridge is not exposed to the outside of the holder, and the glass body and the barrel tip are Since it is protected inside the holder formed by, there is a risk that the glass cartridge will be damaged or damaged compared to the conventional outer cylinders 5 and 30 for a container / syringe shown in FIGS. 4 and 6. It also has the effect of significantly reducing

[Brief description of drawings]

FIG. 1 is a vertical sectional view showing an example of implementation of the present invention.

2 is a partially omitted enlarged vertical sectional view of the one shown in FIG. 1. FIG.

FIG. 3 is a vertical cross-sectional view showing a usage state of the one shown in FIG.

FIG. 4 is a vertical sectional view showing a first example of a conventional technique.

FIG. 5 is a vertical sectional view showing a second example of the prior art.

FIG. 6 is a vertical sectional view showing a third example of the prior art.

[Explanation of symbols]

 110 Cylindrical Body 115 Protrusions for Fingering 117 Outer Wall Surface of Cylindrical Body 120 Glass Cartridge 122 One End of Glass Cartridge 130 Stopper 140 Tube Tip 141 Bottom of Tube Tip 142 Outer Wall Surface of Bottom of Tube Tip 143 Injection Needle Mounting Section 144 Bottom of Tube Tip Inner wall surface 145 through hole 150 holder

Claims (1)

[Scope of utility model registration request] 1. A bottomless tubular glass cartridge is fitted and locked to a bottomless tubular tubular body made of synthetic resin, and the bottom end tubular barrel made of synthetic resin is the tubular body. A rubber stopper that is connected to the glass cartridge and that closes one end of the glass cartridge is compressed and sandwiched between the tube tip and the glass cartridge, and inside the holder formed by the tubular body and the tube tip. The glass cartridge and the stopper are held, and the barrel tip has an injection needle mounting portion protruding from the outer wall surface of the bottom portion, and a through hole extending from the tip of the central portion of the mounting portion to the inner wall surface of the bottom portion. Has and
An outer cylinder for a container / syringe, wherein the cylindrical body has a protrusion for finger-holding on an outer peripheral wall surface thereof.