JPH0641112Y2 - Freeze dryer - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Object of the Invention] (Field of Industrial Application) This invention relates to a freeze-drying apparatus.

(Prior Art) In general, freeze-drying is a well-established drying method whereby, for example, drugs such as vaccines, vitamin preparations, and antibiotics are dried and stored. The water-soluble product in the sample container to be dried is directly converted from ice into sublimation water vapor by operating the vacuum pump, and the frozen sample does not go through the intermediate liquid stage. If such a large amount of sublimated water vapor condenses in the vacuum pump and adversely affects the vacuum device, it is designed to be collected by the adsorbent filled in the condenser body. It has a structure formed separately from.

(Problems to be solved by the invention) As described above, in the conventional freeze-drying apparatus, since the sublimation steam generated from the sample is collected by the condenser formed separately, the entire apparatus becomes large, and even the condenser is increased. There was a problem that the collection efficiency deteriorates due to the extended passage resistance.

Therefore, an object of the present invention is to provide a freeze-drying device which can be miniaturized and is very preferable in terms of collection efficiency.

[Configuration of the Invention] (Means for Solving the Problems) In order to achieve the above object, in the present invention, a sample container communicating with the inside of the chamber body is provided on the outer periphery of the chamber body sealed by an opening / closing lid. While being removably mounted, an adsorption passage filled with an adsorbent is formed in the chamber body, and a connection portion connectable to a vacuum pump is provided at a passage terminal portion of the adsorption passage.

(Operation) According to this freeze-drying apparatus, the sublimation water vapor generated from the inside of the sample container by the operation of the vacuum pump connected to the connecting portion is directly collected by the adsorbent when passing through the adsorption passage. Therefore, the collection efficiency is improved, and the sample container directly connected to and communicated with the chamber body can be downsized.

(Embodiment) An embodiment of the present invention will be described in detail below with reference to the drawings of FIG. 1 and FIG.

In the figure, reference numeral 1 denotes a chamber body formed in a cylindrical shape, which is closed by an opening / closing lid 3.

The chamber body 1 has a first partition wall 5 formed in a cylindrical shape and having a porous cylindrical body 21 inside, and a second partition wall 9 provided with a large number of communication ports 7 at its lower end and upper and lower parts. A labyrinth-like suction passage 13 is formed by the opened third partition wall 11, and the first partition wall 5 is open at the top and is detachably inserted. Further, a connection portion 17 which is connected to and communicates with the vacuum pump 15 is provided at a passage terminal portion of the adsorption passage 13.

The adsorption passage 13 is filled with an adsorbent 19 such as a molecular sieve, and the adsorbent 19 traps sublimated water vapor and reaches a saturated state.
Can be taken out completely by lifting the first partition wall 5 upward, and the newly regenerated adsorbent can be replaced.

Reference numeral 23 denotes a control valve provided on the ceiling of the second partition wall 9, which is opened at the time of regeneration and is the second partition wall 9
This is for letting the steam generated from the inner adsorption passage 13 escape to the outside.

On the other hand, a plurality of rubber connecting pipes 25 are fixed to the outer periphery of the chamber body 1, and the connecting pipes 25 are made of synthetic resin adapter 27.
A sample container 29 is detachably attached via the. The cap 31 that connects the adapter 27 and the sample container 29 is made of rubber so that the seal of the connection area can be ensured in a vacuum.

The connecting pipe 25 is provided with a rotatable inner plug 33, and the inner plug 33 is provided with a first port 35 and a second port 37, respectively. The first port 35 comes into communication with the inside of the chamber body 1 by facing the container passage 39 as shown in FIG. Further, the second port 37 is provided at a position shifted by 180 degrees from the first port 35, and when the first port 35 and the container passage 39 are connected and communicated with each other, the second port 37 is in an idle state and the inner plug 33 is opened. 180
When rotated once, the opening 41 provided in the connecting pipe 25 and the container passage 39 communicate with each other at the same time. As a result, outside air is introduced into the chamber body 1 under vacuum, and the opening / closing lid 3 and the sample container 29 can be removed.

In the freeze-drying apparatus configured as described above, the sublimation steam generated in the sample container 29 by the operation of the vacuum pump 15 directly passes through the adsorption passage 13 and is adsorbed by the adsorbent 19 when passing through the adsorption passage 13. For this reason, the vacuum pump 15
Will not be adversely affected and an efficient adsorption state will be obtained.

Further, since the sample container 29 is directly attached to the outer periphery of the chamber body 1, the entire mounting is small and compact.

[Effects of the Invention] As described above, according to the freeze-drying apparatus of the present invention, the sublimation water vapor generated from the sample container can be directly adsorbed by the adsorbent in the adsorption passage, so that the adsorption efficiency can be improved and the entire apparatus can be improved. Can be made compact.

[Brief description of drawings]

FIG. 1 is a sectional view of the freeze-drying apparatus of the present invention, and FIG. 2 is an enlarged sectional view of a sample container mounting portion. 1 ... Chamber body 3 ... Open / close lid 13 ... Adsorption passage 15 ... Vacuum pump 17 ... Connection 19 ... Adsorbent 29 ... Sample container

Claims (1)

[Scope of utility model registration request] 1. A sample container communicating with the inside of the chamber body is detachably mounted on the outer periphery of the chamber body closed by an opening / closing lid, and an adsorption passage filled with an adsorbent is formed in the chamber body to perform adsorption. The freeze-drying device is characterized in that a connection portion that can be connected to a vacuum pump is provided at a passage terminal portion of the passage.