JPH0632656B2 - Medical container pressurizing device - Google Patents

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a pressurizing device used for administering a medical fluid such as glucose, amino acid, Ringer, etc. filled in a medical container to a patient. The present invention provides a pressurizing device that can reliably administer a drug solution to a patient by applying pressure.

[0002]

2. Description of the Related Art The applicant of the present application has previously proposed a liquid drip control device (Japanese Patent Application No. 61-299944 and Japanese Patent Application Laid-Open No. 63-153073). With this device, the amount of drug solution can be accurately controlled, but in the case of hypertensive patients or when the patient moves during the drip and the blood vessel becomes occluded, the drip rate becomes slow, or in the worst case There were cases where a defective phenomenon such as dropping stopped occurred. In addition, it was difficult to increase the dropping speed even when rapid dropping was desired.

In addition, in the device called an infusion pump which is usually used, the phenomenon of stopping the drip can be prevented, but since an excessively high pressure is added at the time of the drip, the drug solution directly hits the blood vessel and damages the blood vessel, and drip leakage is caused. It was easy to wake up. In addition, since the flow of the drug solution is pulsating in principle,
Blood flowed back into the needle, causing blood clots, which caused the blockage of blood vessels. Therefore, the present inventor has arrived at the next invention as a result of extensive studies to solve the above problems.

[0004]

As a first aspect of the present invention, the present invention comprises a pressurizing chamber 2 and a pressurizing section 3, and the pressurizing chamber 2 includes a medical container 4 filled with a drug solution. The pressurizing container 5 that pressurizes is housed, and the pressurizing unit 3 includes an air pump 7 that pumps air into the pressurizing container 5, a sensor 6 that detects the pressure of the air, and a detection signal thereof. To provide a pressurizing device 1 including a control circuit 9 which controls the air pump 7 to adjust the pressure in the pressurizing container 5.

As a second invention, in the pressurizing device described in the first invention, instead of the pressurizing chamber 2 for accommodating the pressurizing container 5, air is directly sent to the interior to fill the chemical liquid. The present invention provides a pressurizing device 21 in which a pressurizing chamber 22 for pressurizing the medical container 4 is arranged.

As a third invention, in the pressurizing device described in the first invention, a bubble sensor 33 and a clamp 34 are provided.
The pressure device 31 is provided with a flow path monitoring device 32 having

As a fourth invention, in the pressurizing device described in the third invention, a flow path monitoring device 42 provided with an automatic clamp 44 instead of the flow path monitoring device 32 and a drip detection device 43 are added. A pressure device 41 is provided.

As a fifth invention, in the pressurizing device described in the first invention, a pressurizing band 62 is arranged in place of the pressurizing chamber 2 and the pressurizing container 5, whereby the chemical solution is filled. The present invention provides a pressurizing device 61 adapted to pressurize the medical container 4.

As a sixth invention, in the pressurizing device described in the third invention, instead of the pressurizing device 2 and the pressurizing container 5, a ventilating needle 72 and a disinfection filter-73 are arranged, The present invention provides a pressurizing device 71 adapted to pressurize the medical container 44 filled with the drug solution through.

A seventh aspect of the present invention provides a pressure device 81 according to the third aspect, further comprising a pressure sensor 82.

As an eighth invention, in the pressurizing apparatus described in the first to seventh inventions, a compressor pipe 92 is arranged instead of the air pump 7, and a pressure adjusting valve 93 and a pressure adjusting valve control are further provided. A pressurizing device 91 provided with a part 94 is provided.

[0012]

The medical container 4 filled with the drug solution is pressurized by the pressure container 5 and the like, and the pressure applied to the pressure container 5 and the like is adjusted by the control circuit 9 to stably drip the drug solution to the patient. can do.

[0013]

DESCRIPTION OF THE PREFERRED EMBODIMENTS FIG. 1 is a schematic view of a pressurizing device 1 according to the first invention of the present application, and FIG. 2 is a block diagram for operating the pressurizing device 1. The pressure device 1 includes a pressure chamber 2 and a pressure unit 3. The pressurizing chamber 2 is a medical container 4 filled with a drug solution.
A pressurizing container 5 for pressurizing the medical container 4 is formed so as to be accommodated therein. The medical container 4 may be a bag-shaped one or a bottle-shaped one as long as it is made of a flexible synthetic resin.

The pressurizing container 5 is made of a stretchable material such as flexible synthetic resin or synthetic rubber, and can be externally applied to the medical container 4 by expanding in the pressurizing chamber 2. The pressurizing unit 3 detects the pressure of the air pump 7 that sends air into the pressurizing container 5, the pressure sensor 6 that detects the pressure of the air, and the pressure of the pressure sensor 6, and outputs the detection signal. And a control circuit 9 which controls the air pump 7 to adjust the pressure in the pressure vessel 5.

At the end of the operation, the air in the pressurizing container 5 can be released by the pressure release valve 10. This operation can be performed manually or automatically. A check valve 11 is arranged between the air pump 7 and the pressurizing container 5 to prevent the air pumped by the air pump 7 from flowing backward when the air pump 7 is at rest.

A hanger 14 for hooking the medical container 4 is formed in the pressurizing chamber 2. Furthermore, a lid 15 that can be opened and closed is provided in front of the pressurizing chamber 2 with a hinge 15.
It is attached via a. A handle 15b is attached to the lid body 15. Further, in FIG. 2, 8 is a four-way circuit connecting pipe, and 12 is a power source.

Next, an example of use of the present invention will be described.
The medical container 4 filled with the drug solution is placed in the pressurizing chamber 2, and the infusion set 13 is connected to the medical container 4. Power source 12
After setting to N, air is pumped into the pressurized container 5 from the air pump 7.

The control circuit 9 detects the output of the pressure sensor 6 and controls the air pump 7 so as to reach the set pressure. The pressure can be constantly monitored by the pressure gauge 16. Since the pressurized container 5 expands and presses the medical container 4, the drug solution filled in the medical container 4 is administered to the patient via the chamber 13a of the infusion set 13 and the needle 13b. By maintaining the pressure in the pressurized container 5 at a predetermined pressure even if the amount of the drug solution decreases, the drug solution can be stably administered to the patient.

FIG. 3 shows a pressurizing device 2 according to the second invention of the present application.
1 is a schematic view of the first invention (hereinafter, the second invention and the following inventions, the first and second inventions are common to the first and second inventions.
Of the invention is used as is). The pressure device 21 is
Air is directly fed into the pressurizing chamber 22 to apply pressure to the medical container 4 to administer the drug solution to the patient. The pressure control method and other components are the same as those of the pressurizing device 1 of the first invention.

FIG. 4 shows the pressurizing device 3 according to the third invention of the present application.
1 is a schematic view of 1. The pressurizing device 31 is the pressurizing device 1 of the first aspect of the present invention in which a flow path monitoring device 32 having a bubble sensor 33 and a clamp 34 is additionally provided.

By interlocking the flow path monitoring device 32 with the control circuit 9, the presence or absence of air passage is determined by the bubble sensor 33, and the tube 13c is closed by the clamp 34 immediately when the air is detected. Thus, air can be prevented from entering the patient.

The bubble sensor-33 is capable of detecting bubbles of 0.01 ml or more by an ultrasonic system (a system for determining the amount of attenuation of ultrasonic wave propagation). The detected amount of air can be set in advance. Further, when an infrared light emitting / receiving element is used instead of the ultrasonic method, air can be detected with the same accuracy. Besides, a photoelectric method (visible light), an electrostatic method, or the like can be used.

When air is detected, the tube 13c can be clamped and the buzzer can be made to ring at the same time. The pressure control method and other components are the same as those of the pressurizing device 1 of the first invention.

FIG. 5 shows the pressurizing device 4 according to the fourth invention of the present application.
In the schematic view of FIG. 1, the flow path monitoring device 32 of the third invention is further provided with a flow path monitoring device 42 provided with an automatic clamp 44 and a drip detection device 43. The automatic clamp 44 and the drip detection device 43 are interlockedly controlled, and the automatic clamp 44 is operated and controlled based on the detection result of the drip detection device 43.

FIG. 6 is an enlarged view of the automatic clamp 44. The automatic clamp 44 includes a moving body 45, a drive motor 46 for the moving body 45, and a position detection sensor-4 for the moving body 46.
7a (lower limit sensor), 47b (upper limit sensor) and a pressing plate 48 of the tube 13c. 5
1, 52 are bearings.

That is, the power is transmitted from the drive motor 46 to the shaft 46a and the moving body 45, and the vertical movement of the rotary wheel 49 attached to the moving body 45 is controlled to set the number of drops of the chemical solution. You can In addition, tube 1 with rotating wheel 49
When pushing 3c, the shaft 49b with a small diameter bends slightly so that the shaft 49b is extended and the rotating wheel 49a and the guide 50 are extended.
Since the bending is prevented by this, the drip control can be surely performed.

Control of the automatic clamp 44 and pressure is performed as follows. First power source for automatic clamp 44 (not shown)
Is turned on to move the moving body 45 to the lock position (lower side) to set the number of liquid drops of the chemical solution. Next, a start switch (not shown) is turned on to move the moving body 45 upward so that the set number of drops is reached. At the same time, the pressure vessel 5
The medical container 4 is pressurized with to adjust the pressure so that the pressure is slightly higher than the venous pressure of the patient. Pressure is 0 to 100m
It can be varied within the range of mHg.

When air is detected by the bubble sensor 33, the tube is closed by the clamp 34, pressurization is stopped, and the buzzer is caused to ring. The detailed pressure control method and other components are the same as those of the pressure device 1 of the first invention.

FIG. 7 shows a pressurizing device 6 according to the fifth invention of the present application.
In the schematic view of FIG. 1, instead of the pressurizing chamber 2 and the pressurizing container 5 of the pressurizing device 1 of the first invention, a pressurizing band 62 is wound around the medical container 4 and pressure is applied to the medical container 4. A drug solution is administered to a patient. The pressure band 62 has a hollow inside like the blood pressure measurement band, and is made of a stretchable material such as cloth, flexible synthetic resin, or synthetic rubber so that it can be stretched by sending air under pressure. Has been formed. The detailed pressure control method and other components are the same as the pressure device 1 of the first invention.
Is the same as

FIG. 8 shows a pressurizing device 7 according to the sixth invention of the present application.
In the schematic view of FIG. 1, instead of the pressurizing chamber 2 and the pressurizing container 5 of the pressurizing device 31 of the third invention, a ventilating needle 72 and a sterilizing filter-7 are provided.
3 directly into the medical container 74 made of an inflexible material (eg, glass or hard synthetic resin).
Is delivered under pressure to apply the pressure to the drug solution and administer it to the patient. Detailed pressure control method and other components are
It is the same as the pressurizing device 1 of the first invention.

FIG. 9 shows a pressing device 8 according to the seventh invention of the present application.
In the schematic view of FIG. 1, a pressure sensor-82 (mounted near the needle 13b of the infusion set) is attached to the pressurizing device 31 of the third invention. The pressure near the needle 13b of the infusion set is detected, and the control circuit 9 is controlled so that this pressure becomes constant. With this, it is possible to control so that a constant pressure is always generated with respect to the venous pressure of the patient.

The pressure sensor 82 is, for example, the tenth
As shown in the figure, a method 8 in which the expansion of the telescopic chamber-83 attached to the tube 13c is directly detected by the sensor-84.
2a (85 in FIG. 10 is a protective material for the sensor 84 made of a flexible synthetic resin that can expand and contract, and 86 is a lead wire) and the pressure in the tube 13c as shown in FIG. 8 to detect air with a sensor-87 via a ventilation filter-86
2b (88 in FIG. 11 is a lead line).

FIG. 12 is a block diagram of a pressure device 91 according to the eighth invention of the present application. FIG. 13 shows a system in which a compressor pipe 92 for supplying external high pressure air is used instead of the air pump 7 of the pressurizing device 1 of the first invention.
A new pressure control valve 93 is provided to control the high pressure air.
(For example, a needle valve) and a pressure control valve control unit 94 are arranged.

High pressure air from the compressor pipe 92
The air is pressure-fed into the pressurizing chamber 2 through the check valve 11 and the pressure control valve 93. The pressure detected by the pressure sensor 6 is fed back to the control circuit 9 to control the pressure control valve control section 94. In the pressurizing device 91, the check valve 11 is not always necessary because the air pressure is high.

The compressor pipe 92, the pressure control valve 93 (for example, a needle valve), and the pressure control valve control section 94 of the pressurizing device 91 include the pressurizing device 21 of the second to seventh inventions described above. Also in 31, 41, 61, 71, 81, it can be applied when high pressure is desired to be used.

Next, an experimental example of the present invention will be described. Experimental Example 1 Pressurizing device 101 shown in FIG. 13 (pressurizing device 21 in FIG. 3)
Branch tube 102 to tube 13C near needle 13b of
And a pressure measuring device 104 mounted via a filter 103) were used to measure the fluctuations in the pressurizing device set pressure and the infusion pressure. At the time of measurement, the controller 9 sets the air pressure to 20 to 100 mmHg, and the needle 1 at that time is set.
The pressure of the tube 13C near 3b was measured by changing the diameter of the needle 13b. The drop from the liquid surface of the medical container 4 to the needle 13b was measured at 30 cm. The results are shown in FIG. From the results shown in FIG. 14, the transfusion pressure can always maintain a high degree of correlation with the set pressure.

Experimental Example 2 Pressure device 111 shown in FIG. 15 (a pressure measuring device 104 via a branch tube 102 and a filter 103 to a tube 13C near the needle 13b of the pressure device 1 in FIG. 1). The pressure change of the set pressure of the pressurized container 5 and the transfusion pressure were measured with time. The results are shown in FIG. First
According to the results shown in FIG. 6, when the amount of the drug solution in the medical container 4 decreases with the lapse of time, the medical container 4 cannot be evenly pressurized, and the infusion pressure maintaining power gradually decreases. The pressurizing device 111 does not require much injection accuracy, but is effective when it is desired to end the injection within a certain time, when the patient's blood pressure is high, and it is difficult to inject the drug solution into the patient by natural dropping. Further, the pressurizing device 111 is advantageous in that the manufacturing cost of the device can be made lower than that of the air pressurizing type pressurizing device 101.

Experimental Example 3 Pressurizing device 121 shown in FIG. 17 (pressurizing device 21 in FIG. 3)
The conventional liquid dropping control device 122 (Japanese Patent Application No. 61-299)
No. 944, Japanese Patent Laid-Open No. 63-153073, which is equipped with a device composed of a sensor-123 and a control device 124), and the set number of drops and changes with time were measured. The result is shown in FIG. 18 (the drop from the liquid surface of the medical container 4 to the needle 13b is 1 m, and the diameter of the needle 13b is 2 m).
4G was used). Pressurizing device 121 of Experimental Example 3
Then, it was possible to accurately control 95 drops against the set drop number of 95 drops / min. On the other hand, the conventional liquid dropping control device 12
In the case of 2, the drop number was set to 95 drops / min, and from 54 drops to 59 drops
Only drops (55 drops on average) could be controlled.

Experimental Example 4 Pressurizing device 131 shown in FIG. 19 (pressurizing device 21 in FIG. 1)
The conventional liquid dropping control device 122 (Japanese Patent Application No. 61-299)
No. 944, Japanese Patent Laid-Open No. 63-153073, which is equipped with a device composed of a sensor-123 and a control device 124), and the set number of drops and changes with time were measured. From the result of FIG. 20, when the set amount of drops is 95 drops / min and the amount of the drug solution in the medical container 4 decreases with the lapse of time, the medical container 4 cannot be evenly pressurized, and thus the maintenance of the number of drops is slightly small. However, the pressurizing device 131 has the same merit as the pressurizing device 111.

[0040]

As described above, according to the present invention, since excessive pressure is not applied to the drug solution, the blood vessel of the patient is not damaged and drip leakage can be prevented.
Since the flow of the infusion is continuous, continuous infusion without pulsation can be performed, and coagulation at the needle tip of the infusion set can be prevented.

A pressure slightly higher than the venous pressure at the puncture part of the needle can be applied and can be varied within the range of 0 to 100 mmHg. Therefore, even if the blood pressure of the patient rises or the blood vessel becomes close to occlusion, it is dripped. Can be prevented. When combined with a liquid drip control device that does not have a pump function, accurate infusion can be performed without stopping drip. And so on.

[Brief description of drawings]

FIG. 1 is a schematic view of a pressure device according to a first invention of the present application.

FIG. 2 is a block diagram for operating a pressure device.

FIG. 3 is a schematic view of a pressure device according to a second invention of the present application.

FIG. 4 is a schematic view of a pressure device according to a third invention of the present application.

FIG. 5 is a schematic view of a pressure device according to a fourth invention of the present application.

FIG. 6 is an enlarged view of an automatic clamp attached to the pressure device of the fourth invention of the present application.

FIG. 7 is a schematic view of a pressure device according to a fifth invention of the present application.

FIG. 8 is a schematic view of a pressure device of a sixth invention of the present application.

FIG. 9 is a schematic view of a pressure device according to a seventh invention of the present application.

FIG. 10 is a sensor attached to the pressure device of the seventh invention.
Schematic of

FIG. 11 is a sensor attached to the pressure device of the seventh invention.
Schematic of

FIG. 12 is a block diagram of a pressure device according to an eighth invention of the present application.

FIG. 13 is a schematic view of a pressure device used in Experimental Example 1 of the present application.

FIG. 14 is a graph showing the results of Experimental Example 1.

FIG. 15 is a schematic view of a pressure device used in Experimental Example 2 of the present application.

16 is a graph showing the results of Experimental Example 2.

FIG. 17 is a schematic view of a pressure device used in Experimental Example 3 of the present application.

FIG. 18 is a graph showing the results of Experimental Example 3.

FIG. 19 is a schematic view of a pressure device used in Experimental Example 4 of the present application.

FIG. 20 is a graph showing the results of Experimental Example 4.

[Explanation of sign]

 1 Pressurizing Device 2 Pressurizing Chamber 3 Pressurizing Section 4 Medical Container 5 Pressurizing Container 6 Sensor-7 Air Pump 8 Pressure Control Valve 9 Control Circuit

Claims (8)

[Claims] 1. A pressurizing chamber 2 and a pressurizing unit 3, wherein the pressurizing chamber 2 houses a pressurizing container 5 for pressurizing a medical container 4 filled with a drug solution, and the pressurizing unit 3 Is the pressure vessel 5
An air pump 7 for sending air under pressure, a sensor 6 for detecting the pressure of the air, and a detection signal for controlling the air pump 7 so that the pressure in the pressurized container 5 can be adjusted. A pressurizing device 1 for the medical container 4 (hereinafter referred to as "pressurizing device 1"), which comprises a control circuit 9. 2. In the pressurizing device according to claim 1, instead of the pressurizing chamber 2 accommodating the pressurizing container 5, air is directly sent to the inside of the pressurizing chamber to fill the chemical liquid. A pressurizing device 21 having a pressurizing chamber 22 for pressurizing the medical container 4. 3. The pressurizing device 31 according to claim 1, further comprising a flow path monitoring device 32 having a bubble sensor 33 and a clamp 34. 4. The pressurizing device according to claim 3, wherein instead of the flow passage monitoring device 32, an automatic clamp 44 is attached to the flow passage monitoring device 42 and the drip detection device 43.
The pressurizing device 41 is characterized in that. 5. The pressurizing device according to claim 1, wherein a pressurizing band 62 is arranged in place of the pressurizing chamber 2 and the pressurizing container 5, whereby the chemical solution is filled. A pressurizing device 61, which is configured to pressurize the medical container 4. 6. The pressurizing device according to claim 3, wherein, instead of the pressurizing device 2 and the pressurizing container 5, a ventilating needle 72 and a sterilizing filter-73 are arranged and passed through them. A pressurizing device 71, which is configured to pressurize a medical container 74 filled with a drug solution. 7. A pressurizing device 81 according to claim 3, further comprising a pressure sensor-82. 8. A pressurizing device according to any one of claims 1 to 7, wherein a compressor pipe (92) is arranged instead of the air pump (7), and a pressure control valve (93) is provided.
And a pressure control valve control unit 94 attached thereto.