JPH06298616A - Antifungal and antimold agent and its production - Google Patents

Abstract

PURPOSE:To provide an antifungal and antimold composition by fixing metallic ions having oligodynamic action including silver to an inorganic ion exchanger firmly and its production process. CONSTITUTION:The objective antifungal and antimold agent is composed of 0.01 to 10wt.% of at least one selected from silver, copper and zinc, 1 to 50wt.% of calcium phosphate and the remaining of glass phase.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to an antibacterial and antifungal agent and a method for producing the same. More specifically, the present invention relates to an antibacterial and antifungal agent which is used for performing antibacterial and antifungal treatments on industrial products such as plastics, fibers, cement, concrete and ceramics, and a method for producing the same.

[0002]

2. Description of the Related Art Conventionally, organic antibacterial and antifungal agents have been widely used. However, in recent years, inorganic materials such as silver, copper, and zinc which utilize the oligodynamic effect are excellent in safety and durability, and therefore the opportunities for application have increased.

Inorganic antibacterial and antifungal agents are roughly classified into two types. One of them is an inorganic ion exchanger in which an oligodynamic metal ion is supported in an aqueous solution by an ion exchange reaction. The other is a solution of oligodinamy metal ions dissolved in water-soluble glass. The former ion-exchange-supported one, in which the oligodinamy metal ion supported on the ion-exchanger exhibits antibacterial and antifungal properties, and the latter one dissolved in water-soluble glass, is accompanied by the dissolution of the glass. It is considered that the released oligodynamic metal ions exert antibacterial and antifungal properties.

A problem with such conventional inorganic antibacterial and antifungal agents is that when silver ions are contained, the color changes as the silver ions elute. The silver ion carried by the aqueous solution reaction on the inorganic ion exchanger has a weak binding force for carrying, and is eluted and discolored. If the ion exchanger is treated at a high temperature for this improvement, the binding force will be increased and the discoloration will be slightly reduced, but it is still not sufficient. Further, the one in which silver ions are dissolved in water-soluble glass cannot avoid discoloration because silver ions are eluted as the glass is dissolved.

[0005]

Therefore, the present invention has been invented to solve the above-mentioned various problems, in which a metal ion such as silver is used as an inorganic ion exchanger. Based on the fact that if it can be bound more firmly, discoloration is considered to be hardly observed, based on the fact that the inorganic ion exchanger can firmly fix metal ions having an oligodynamic effect such as silver, antibacterial and preventive It is an object of the present invention to provide a mold composition and a method for producing the same.

[0006]

According to the present invention, in order to solve the above technical problems, the content of at least one metal selected from silver, copper and zinc is 0.01 to 10% by weight. The present invention provides an antibacterial and antifungal agent having a calcium phosphate content of 1 to 50% by weight and the rest being a glass phase.
Further, according to the present invention, after calcium phosphate is supported with silver in an aqueous solution, this is mixed with glass powder, and the mixture is mixed with 7
A method for producing an antibacterial and antifungal agent, which comprises heating the mixture to a high temperature of 00 ° C. or higher to fluidize the glass component, and then rapidly cooling the mixture, and a calcium phosphate and a silver compound. , Glass powder is mixed, and this mixture is
It is a method for producing an antibacterial and antifungal agent, which comprises heating the mixture to a high temperature of 700 ° C. or higher to fluidize the glass component and then rapidly cooling the mixture.

That is, there are two methods for producing antibacterial and antifungal agents:
There is a street. One of them is to support a metal such as silver on calcium phosphate. That is, calcium phosphate and a water-soluble silver compound such as AgNO ₃ or AgF are mixed in an aqueous solution. Next, this and glass powder are mixed.
The composition of the glass powder is not particularly limited, but frit of borosilicate glass is preferable because it has good fluidity when melted. These mixtures are heated to a high temperature of 700 ° C. or higher, preferably to a temperature of 1000 to 1200 ° C. to sufficiently dissolve and fluidize the glass component. Then, this is rapidly cooled, preferably in water, to obtain an antibacterial and antifungal agent. The antibacterial and antifungal agents are used after finely pulverized as needed.

Here, the content of at least one metal selected from silver, copper and zinc is in the range of 0.01 to 10% by weight. If it is less than 0.01% by weight, a sufficient effect cannot be obtained, and if it exceeds 10% by weight, discoloration occurs. The content of calcium phosphate is preferably 1 to 50% by weight. This is because if it is less than 1% by weight, the antibacterial and antifungal effects are not sufficient, and if it exceeds 50% by weight, discoloration occurs. The composition of calcium phosphate is preferably such that the molar ratio of Ca and P is Ca / P = 1.5 to 1.7. It is preferable to further contain 3 to 4% by weight of fluorine.

Another method is to prepare a compound such as calcium phosphate, silver (eg, silver phosphate, silver chloride), glass powder (preferably a frit of borosilicate glass, 10
(Which fluidizes at 00 to 1200 ° C) are mixed, and 700
The glass powder is melted and fluidized by heating it to a high temperature of ℃ or more, and this is rapidly cooled, preferably water cooled.

[0010]

In the antibacterial and antifungal agent of the present invention, the role of the metal components of silver, copper and zinc is the expression of antibacterial and antifungal properties,
The role of calcium phosphate is to become a carrier for metals such as silver. In addition, the role of the glass phase, metal such as silver,
It is a solvent that helps the calcium phosphate to be supported.

Calcium phosphate can support a metal such as silver even in a reaction in an aqueous solution, but its binding force is small, so that the metal such as silver is easily liberated and discolored easily. However, like the antibacterial and antifungal agent of the present invention, when it is carried in molten glass, the binding force becomes large, and the metal such as silver is less likely to be liberated, so that discoloration is less likely to occur.

This method is essentially different from the binding force by heating, and is for obtaining a strong binding force by causing an ion exchange reaction in the glass melt. As described above, the feature of the antibacterial and antifungal agent of the present invention is that an antibacterial and antifungal agent which does not discolor can be obtained by supporting a metal ion such as silver on an inorganic ion exchanger in a glass melt. .

The oligodynamic effect of metal ions such as silver does not appear with the elution of the ions.
That is, the active oxygen is generated by using the supported metal ions such as silver ions as a catalyst, and when the active oxygen is present, the oligodynamic effect is exhibited. Therefore, even an inorganic ion exchanger carrying metal ions such as silver ions that do not elute like the antibacterial and antifungal agent of the present invention can exhibit antibacterial and antifungal effects.

Next, the present invention will be specifically described with reference to examples, but the present invention is not limited thereto.

[0015]

Example Synthesis of calcium phosphate Phosphoric acid was added dropwise to a calcium hydroxide slurry to synthesize calcium phosphate. Two Ca / P molar ratios of 1.5 and 1.67 were prepared. Also, 1.6
7: 4% by weight of fluorine (by adding NaF)
The added one was also created.

Loading of Silver in Aqueous Solution (Method of Loading Silver in Aqueous Solution ) Silver was loaded on the three types of calcium phosphate synthesized as described above. The supporting method was carried out by adding silver nitrate to an aqueous suspension of calcium phosphate and stirring for 24 hours.
The amount of silver supported was 1% by weight based on the solid content.

Mixing with glass powder To each of the three types of calcium phosphate prepared by the above-mentioned synthesis of calcium phosphate, silver phosphate is added in such a manner that the silver content is 1% by weight based on calcium phosphate, and the frit of borosilicate glass is used. Was added by 4 times the amount of calcium phosphate and mixed by a ball mill (direct mixing method). Further, to each of the three types of silver-supported calcium phosphate prepared by the silver-supported method in an aqueous solution, a borosilicate glass frit was added in an amount four times that of calcium phosphate and mixed by a ball mill.

Melting and Cooling of Glass Each of the six types of mixtures prepared above was heated to 1100 ° C. to melt the glass component mixture. The melt was dropped in water and cooled. The obtained solidified product was pulverized with a ball mill to an average particle size of 10 μm.

Color Change Test The color change properties of the 6 types of powder samples prepared above were tested. In the test method, 1 g of a powder sample was kneaded into 100 g of an acrylic emulsion resin, irradiated with sunlight for 24 hours, and the discoloration was visually observed. According to this test method, antibacterial and antifungal agents, which easily dissolve silver, are discolored when tested. The test results are shown in Table 1.

[0020]

[Table 1]

The raw materials and preparation methods described in the examples are merely examples, and as long as they meet the purpose of the present invention, various combinations of raw materials to be used, preparation methods, preparation processes and the like may be used. You may use.

[0022]

As described above, the following remarkable technical effects are obtained by the antibacterial and antifungal agent of the present invention, the method for producing the same, and the structure using the same. Provided are a composition of an antibacterial and antifungal agent capable of firmly fixing a metal ion having an oligodynamic effect such as silver to an inorganic ion exchanger, and a method for producing the same. That is, a metal ion such as silver can be bound to an inorganic ion exchanger more firmly than before, and discoloration is hardly observed.
An antifungal agent and a method for producing the same are provided.

Front page continuation (72) Inventor Nobuyuki Kumakura 585 Tomicho, Funabashi, Chiba Sumitomo Cement Co., Ltd. Central Research Laboratory

Claims (3)

[Claims] 1. The content of at least one metal selected from silver, copper and zinc is 0.01 to 10% by weight, the content of calcium phosphate is 1 to 50% by weight, and the rest is composed of a glass phase. An antibacterial and antifungal agent characterized by 2. Silver is supported on calcium phosphate in an aqueous solution, which is then mixed with glass powder to obtain 70 parts of the mixture.
The method for producing an antibacterial and antifungal agent according to claim 1, which is obtained by heating the mixture to a high temperature of 0 ° C or higher to fluidize the glass component and then rapidly cooling the mixture. 3. A method in which calcium phosphate, a silver compound and glass powder are mixed, the mixture is heated to a high temperature of 700 ° C. or higher to fluidize the glass component, and then the mixture is rapidly cooled. The method for producing an antibacterial and antifungal agent according to claim 1, characterized in that