JPH06256128A - Mite-suppressing agent - Google Patents

Abstract

PURPOSE:To provide a mite-suppressing agent capable of preventing the proliferation of mite in room dust to cause the allergic diseases simply by scattering a proper amount of the agent on a carpet, etc., in the room, leave standing for several minutes and sucking with a vacuum cleaner and, at the same time, having extremely high safety to human body and safely usable in a home with infants. CONSTITUTION:The mite-suppressing powdery agent is produced by impregnating 1-250wt.% of an extract of the ground part, underground part or seed of at least one kind of plant selected from rosemary (Rosemarinus officinalis) or its allied species into a porous adsorbent.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a mite suppressant, the purpose of which is to effectively suppress the growth of mites living in indoor dust that cause allergic diseases or make people uncomfortable. It is intended to provide a mite inhibitor that can be used and is safe and easy to use for the human body.

[0002]

2. Description of the Related Art In recent years, in the living environment of Japan, air conditioners such as cooling in summer and heating in winter are also provided in ordinary households. For this reason, even in the winter, due to the heating equipment, particularly in concrete construction, the humidity tends to be high due to the high degree of tightness, and in addition to the carpet,
Along with the diversification of lifestyles such as the use of sofas and beds (Westernization), mites have become resident in indoor dust, and damage from indoor dust mites is proportional to the improvement of the living environment. It has come to be reported. The mites in house dust, Dermatophagoides farinae (D.farinae), house dust mites such as Dermatophagoides pteronyssinus (D.pteronyssinus) (Dermatophagoides spp (Dermatophagoides)) and Tyrophagus
( Tyrophagus putrescentiae ) occupies the majority of the mites, and the habitat of these mites is mainly pillow covers, sofas, carpets, etc.In Japan's aerobic climate environment, especially carpets and tatami mats. The habitat density is higher in the surface layer than in the inner layer. Most of the damages caused by mites in indoor dust are allergic diseases with the above-mentioned genus Dermatophagoides as an allergen. Flame is a typical example. Examples of measures against such allergic diseases include symptom relief of patients by administration of anti-allergic drugs, desensitization therapy, and constitutional improvement, but improvement of the living environment by actively controlling ticks themselves is possible. This is the most effective measure.

[0003]

2. Description of the Related Art Conventionally, physical control methods and chemical control methods have been used as methods for preventing and controlling the reproduction of mites in a house. Physical control methods include dehumidifying and drying methods such as futon drying at high temperature and sun drying, vacuum cleaners for mites, cleaning dust prevention methods using an air cleaner, or flooring for renovating floors in a house between boards. On the other hand, as the chemical control method, a washing method such as washing the bedclothes or a spray of an acaricide using an organic phosphorus-based or carbamate-based compound such as demeton, diazinon, and sumithion can be mentioned. .

[0004]

However, the above-mentioned method for controlling ticks has the following problems. In other words, in a dehumidification drying method such as Futon drying, the relative humidity is 60
If it is not dried at a temperature of 50% or more at a temperature of 50% or more, the effect of controlling ticks does not appear and there is a problem that it is affected by the weather. Moreover, carpets and other rugs are dried under such conditions. There was a problem that it took a lot of time and labor to do such work frequently. In addition, with dust-proofing methods using an electric vacuum cleaner for ticks and air purifiers, and washing methods such as washing bedding in total, special equipment and a washing machine must be prepared, and it can be easily controlled in general households. It wasn't work. Further, the work called "flooring" for renovating the floor between the boards is effective in that it creates an environment in which mites are difficult to live, but it is expensive and time-consuming and not a simple method. On the other hand, acaricides using organophosphorus or carbamate compounds are highly toxic to the human body, generally few at low concentrations are effective, and some have a strong irritating odor. However, there was a problem that it could not be used with confidence and the spraying place was restricted. Therefore, in the industry, it has been desired to create a mite inhibitor that can be easily used in general households, is safe for the human body, and can effectively prevent the reproduction of mites.

[0005]

According to the present invention, the porous adsorbent is at least one of aboveground, underground and seed of at least one plant selected from rosemary (Rosemarinus officinalis ) and its related species. The above-mentioned conventional problems are alleviated by providing a mite inhibitor characterized by being impregnated with an extract of one site.

[0006]

[Function] Extracts of rosemary (Rosemarinus officinalis ) or its relatives
atophagoides) and acarid mite ( Tyrophagus putresc
entiae ) and the like, and suppresses the growth thereof. Therefore, the porous adsorbent impregnated with this active ingredient is sprayed on household carpets and tatami mats, left for a certain period of time, and then sucked with a normal household vacuum cleaner to easily suppress the growth of indoor dust mites. In addition, since the extract is a natural product as an active ingredient, it is highly safe for the human body, and it is possible to work with peace of mind even at home with infants.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION The constitution of the mite inhibitor according to the present invention will be described in detail below. Rosemary (Rosemarinus officinalis ) used in the present invention, also called "mannen wax", is a perennial perennial shrub with aromatic aromatic Lamiaceae native to the Mediterranean region, whose leaves are used as an herb in meat and vegetable dishes. It is also used in bath salts and fragrance preparations. In addition, rosemary (Rosemarinus off
From the leaves of icinalis ), rosemary oil (Oleum Rosemarini), which contains essential oils such as pinene, cineol, camphene and camphor, is collected and used as a cosmetic material such as fragrance and soap. On the other hand, in China, it is called "strange incense", and the whole plant is used as a medicinal plant for analgesia, sweating, and stomach ache. This rosemary (R
A close relative of osemarinus officinalis is a grape, Los marinus prostratus (R. prostratus)
H _ORT. ) Is exemplified as a useful plant, but is not particularly limited.

[0008] Such rosemary (Rosemarinus off
icinalis ) or any of the above-ground, below-ground, or seed parts of this related species alone or in a mixture of multiple parts, and then either raw or dried and crushed. Or without crushing, extracted with a polar solvent and a non-polar solvent, or a mixed solvent thereof, and optionally concentrated, or without concentration, used as an essential component of a mite suppressor without limitation. It As the extraction solvent,
Water and alcohols such as methanol and ethanol,
One or a mixture of two or more polar solvents such as low molecular weight ketones, esters and ethers having a low molecular weight such as acetone, ethyl acetate and diethyl ether, or n-hexane, petroleum ether, ligroin, cyclohexane and carbon tetrachloride. , Chloroform, dichloromethane, toluene,
One or a mixture of two or more non-polar solvents such as benzene,
Alternatively, a mixed solvent of these polar solvent and nonpolar solvent is preferably used without limitation.

Rosemary (Rosemarinus o
fficinalis ) or an extract of any part of this related species is impregnated into the porous adsorbent to be a mite inhibitor. As a porous adsorbent, when sprayed on indoor carpets, tatami mats, etc., it does not become too powdery, easily adsorbs dust and mites on the surface of carpets, and is easily sucked by an electric vacuum cleaner, Moreover, any powder that is highly safe for the human body can be preferably used, and specifically, porous silica (silicon dioxide), sodium silicate, calcium silicate, active Preferable examples include clay having a pore size of about 0.1 to 0.2 μm, such as clay, activated alumina, and calcium carbonate, but are not particularly limited. For such porous adsorbents, rosemary (Rosemarinus offic
inalis ) or an extract of any part of its related species is 1-2.
50% by weight, more preferably 100% by weight
Impregnated. The reason for this is Rosemary (Rosemarinus off
icinalis ) or a related plant extract thereof having an impregnated amount of less than 1% by weight, it is impossible to effectively suppress the growth of indoor dust mites, which is the object of the present invention.
This is because in the case of more than wt%, the impregnated amount becomes too large, which makes it difficult to spray on a carpet or tatami or to perform suction work with an electric vacuum cleaner, which is not preferable in any case.

The mite inhibitor according to the present invention having the above-mentioned constitution is a priority species of indoor dust, and its carcasses and feces become dust to cause allergic diseases such as asthma and dermatitis, Dermatophagoides. farinae) ,
Chili mites such as Dermatophagoides pteronyssinus, as well as house materials such as furniture and rugs, tend to cause discomfort to humans ( Tyro
phagus putrescentiae ) or spider mites (Ornithonyssus bacoti) , which are predators of these mites, all effectively act on mites found in the human dwelling environment such as tick mites (Cheyletidae ) and these mites Can be effectively prevented from growing. When using this mite inhibitor, for example, carpet,
After spraying an appropriate amount on a tatami mat or the like and leaving it for about 5 to 30 minutes, suction and cleaning may be performed with an electric vacuum cleaner, and mite control work can be easily and effectively performed in a general household. Further, in the mite inhibitor according to the present invention, any colorant, fragrance or the like may be appropriately blended if desired.

Further, the method of using the mite inhibitor of the present invention is not limited to the above-mentioned spraying and suction on carpets, etc., and the mite inhibitor is filled in a breathable bag body, and this bag body is used, for example, as a futon or a futon. Beddings such as pillows and stuffed animals such as mites can be placed inside personal belongings where they can easily propagate, or a porous adsorbent impregnated with the active ingredient can be molded into any shape such as pellets or spheres. Then, it may be installed and used at any place in the home, and any method can be suitably adopted as a method for suppressing the reproduction of mites.

[0012]

EXAMPLES The effects of the mite inhibitor according to the present invention will be further clarified below with reference to Examples and Test Examples.

(Example 1) Rosemary ( Rose marinus o
essential oil was obtained from the dried leaves of fficinalis ) by steam distillation. 100 g of this essential oil was added to porous silica (Tokuyama Soda Co., Ltd.)
(Manufactured: trade name, Tokseal) 100 g was impregnated to prepare the mite inhibitor of Example 1. (Example 2) Rosemary (Rosemarinus officinalis )
100 g of the dried leaf portion of the above was reflux-extracted with 500 g of 50% (W / W) ethanol at 80 ° C. for 3 hours and then filtered to obtain an effective extract. 100 g of this extract was impregnated with 100 g of porous silica (Tokushiru Soda Co., Ltd .: trade name, Tokusil) to prepare the mite inhibitor of Example 2. (Example 3) Example 2 except that water was used as the extraction solvent.
The mite inhibitor of Example 3 was prepared in the same manner as in.

(Comparative Example 1) 0.2 g of a mite-free medium (Oriental Yeast Co., Ltd .; animal feed MF) was prepared and used as a mite inhibitor of Comparative Example 1.

[0015]

[Test example]

(Tick Proliferation Inhibition Test) As a test target mite, Dermatophagoides farinae ( Dermatophagoides farinae ) was used. MF medium (manufactured by Oriental Yeast Co., Ltd .; animal feed M)
200 mites to be tested were mixed in F) and injected into a petri dish with a diameter of 50 cm. A cylindrical container was prepared, and a medium (dishes) containing 200 mites to be tested was placed in this container, and a wool cloth and 0.2 g of the mite inhibitor prepared in Examples 1 to 3 were sequentially placed on this medium. As shown in FIG. 1, stacking and enclosing the opening of the container with a wrap to form a test section, and a control section using the mite-free medium of Comparative Example 1 instead of the mite inhibitor prepared in Example were prepared as shown in FIG. And used as a test container. Store each test container under the conditions of temperature 28 ℃ and humidity 80%,
After 7 days, the number of live mites and dead mites of each petri dish in each test container were measured. This operation was repeated twice, and the average value is shown in Table 1. Further, the mite growth inhibition rate was calculated according to the following formula (Equation 1), and the results are also shown in Table 1.

[Table 1]

[0016]

[Equation 1]

[0017]

As described in detail above, the present invention provides a porous adsorbent containing at least one or more plants selected from rosemary (Rosemarinus officinalis ) and its related species, at least one of above-ground parts, underground parts and seeds. Since it is a mite inhibitor characterized by being impregnated with the extract of any one of the sites, as is clear from the results of the above-mentioned test examples, it is highly effective for dust mites and tatami mats that cause allergic diseases. It can extremely effectively suppress the growth of mites in indoor dust, such as prone mites, and is highly safe for humans because it contains natural extracts as essential ingredients, even in families with infants. It has an excellent effect that it can be easily and safely used.

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[Procedure amendment]

[Submission date] May 27, 1993

[Procedure Amendment 2]

[Document name to be amended] Statement

[Name of item to be corrected] Brief description of the drawing

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[Brief description of drawings]

FIG. 1 is an explanatory view showing a container used in a mite growth suppression test. ─────────────────────────────────────────────────── ───

[Procedure amendment]

[Submission date] May 27, 1993

[Procedure Amendment 1]

[Document name to be amended] Statement

[Correction target item name] 0014

[Correction method] Change

[Correction content]

Comparative Example 1 0.2 g of a mite-free medium (manufactured by Oriental Yeast Co., Ltd .; animal feed MF) was prepared and used as a mite inhibitor of Comparative Example 1.

[Procedure Amendment 2]

[Document name to be amended] Statement

[Name of item to be corrected] 0015

[Correction method] Change

[Correction content]

[0015]

[Test Example] (Tick Proliferation Inhibition Test) As a test target mite, Dermatophagoides
farinae ) was used. 200 mite to be tested were mixed in MF medium (manufactured by Oriental Yeast Co., Ltd .; animal feed MF) and injected into a petri dish having a diameter of 50 cm.
Prepare a cylindrical container and put the test target mites 200 in this container.
A double soil (a petri dish) including the head is set up, and a wool cloth and 0.2 g of the mite inhibitor prepared in Examples 1 to 3 are sequentially stacked on this double soil, and the opening of the container is sealed with a wrap to make a test section. Further, instead of the mite inhibitor prepared in Example, a target section using the mite-free medium of Comparative Example 1 was prepared as shown in FIG. 1 to prepare a test container. Each of the test containers was stored under the conditions of a temperature of 28 ° C. and a humidity of 80%, and the number of live mites and dead mites of each chalet in each test container after 7 days were measured. This operation was repeated twice, and the average value is shown in Table 1. Further, the mite growth inhibition rate was calculated according to the following formula (Equation 1), and the results are also shown in Table 1.

[Table 1]

[Procedure 3]

[Document name to be amended] Statement

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[0016]

[Equation 1]

[Procedure amendment 4]

[Document name to be amended] Statement

[Correction target item name] 0017

[Correction method] Change

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[0017]

INDUSTRIAL APPLICABILITY As described in detail above, the present invention uses a rosemary (Rosemarinus off) as a porous adsorbent.
icinalis ) or at least one or more plants selected from related species above ground, underground or seeds of at least one of the parts of the extract is impregnated with an extract, characterized by a tick inhibitor, As is clear from the results of the above test examples, it is possible to extremely effectively suppress the growth of mites in indoor dust such as dust mites that easily cause outbreaks of dust mites and tatami mats that cause allergic diseases. At the same time, since the natural extract is an essential component, it is highly safe for the human body and has an excellent effect that it can be easily and safely used even at home with infants.

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Akiyo Yoshikawa 3-5-20 Tagawa, Yodogawa-ku, Osaka City Inabata Koryo Co., Ltd.

Claims (1)

[Claims] 1. The rosemary (Rosemarin ) is used as the porous adsorbent.
us officinalis ) or at least one plant selected from related species thereof, and an extract of at least one part of the above-ground part, the underground part or the seed is impregnated therein.