JPH06213147A - Pressure-processing method and device for liquid - Google Patents

Abstract

PURPOSE:To prevent the mixing of a booster side liquid into a processed liquid by making the processed liquid in a sealing body the same as a liquid put between the inside of a container and the outside of the sealing body, or using pure water for the liquid, and monitoring the mixing of the other pressure liquid into the liquid. CONSTITUTION:The processed liquid of a processing liquid tank 1 is filled into a sealing body 5 via a pump 2 and a valve 3. A secondary pressure medium 4 is filled into a barrel 7. The sealing body 5 is fully filled with the processed liquid into the expanded state. The secondary pressure medium 4 is made the same as the processed liquid, or pure water is used for it, and the pressure is preserved by the barrel 7, upper and lower covers 6, 11, and a seal 10. Prior to the filling of the secondary pressure medium 4 into the barrel 7, the high-viscosity oil of a low-pressure liquid tank 35 is boosted by a booster 29 into the primary pressure medium 17, it is filled into the barrel 19, and the pure water of a secondary pressure medium tank 28 is filled into a sealing body 18 and preserved at the prescribed high pressure. When no abnormality is detected in the pure water in the sealing body 18 by a foreign object detecting meter 37, a valve 16 is opened to fill the pressure medium 4 into the barrel 7.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a high pressure liquid used in the pharmaceutical industry, food industry, semiconductor industry and the like.

[0002]

2. Description of the Related Art In recent years, it has been used in the fields of pharmaceuticals, foods, semiconductors, etc., including a method of pressurizing deep-sea seawater for culturing industrially useful bacteria that survive in the deep-sea. The use of pressure has come to be used for the processing and treatment of liquid materials.

As a prior art of the processing / treatment method utilizing the pressure of these liquid materials, it is disclosed in Japanese Patent Application Laid-Open No. 2-182157. An example of this is shown in FIG.

The treatment liquid tank 1 contains a liquid to be subjected to a pressure treatment, for example, a pressurized culture liquid which is seawater containing bacteria collected from the deep sea. It is injected into the processing liquid sealing body 5 through the processing liquid inlet / outlet 12 via the above.

The processing liquid envelope 5 is an elastic body having large elasticity.
For example, it is made of rubber, and is attached to the lower lid 11 by sealing 8.

As described above, the liquid is injected into the treatment liquid sealing body 5, and the secondary pressurizing medium 4, for example, oil is injected from the secondary pressurizing medium inlet / outlet 9 by the pressure booster 29. The operation of the pressure booster will be described below.

First, the low pressure liquid tank 35 contains oil,
This oil is sent by the pump 34, and the low pressure liquid inlet / outlet port 30
When passing through the low pressure side pressure chamber 32, the pressure is increased by the pressure intensifier 29, and the oil in the high pressure side pressure chamber 31 is increased in pressure.

In the case of this example, the pressure corresponding to 10,000 m in the deep sea, that is, the pressure of 100 MPa is the high pressure side pressure chamber 31.
Generated in oil.

The pressure oil of 100 MPa passes through the check valve 33, the valve 16, and enters the secondary pressurizing medium 4 from the secondary pressurizing medium inlet 9 formed in the upper lid 6.

As described above, the liquid to be treated is filled in the treatment liquid envelope 5, and the secondary pressurizing medium 4 on the outer side of the liquid is filled from the full oil state by the pressure increase. When the pressure is increased, the pressure of the secondary pressurizing medium 4 is gradually increased and reaches 100 MPa in about 5 minutes.

At the same time, the liquid in the processing liquid envelope 5 is also 1
Pressurized to 00 MPa.

At this time, the contraction amount of the liquid is about 3.5%, and the rubber of the treatment liquid envelope 4 contracts in accordance with the contraction amount.

Here, the treatment liquid sealing body 5 is a body 7 and a seal 1.
Further, it is held by the upper lid 6, the lower lid 11 and the like.

[0014]

The pressure treatment system according to Japanese Patent Laid-Open No. 2-182157, which is a conventional method as described above, has the following problems.

That is, (1) the liquid to be treated in the treatment liquid envelope 5 must completely block foreign matter from entering, but in some cases the rubber or the like of the treatment liquid envelope 5 may be damaged during use. The secondary pressurizing medium, that is, oil, penetrates into the processing liquid enclosure and contaminates the processing liquid system such as the inside 7 of the barrel and the piping at the inlet and outlet of the processing system.

Generally, the oil used as the secondary pressurizing medium is often highly viscous in order to ensure durability by sliding of the cylinder, piston, etc. of the pressure booster.

Therefore, once the processing liquid system is contaminated,
The production is interrupted, and it is very difficult to restore its cleanliness, for example, by cleaning the processing liquid system, and the productivity is extremely reduced.

(2) Even if the foreign matter detector 39 is provided in the treatment liquid system to constantly detect the contamination of the foreign matter, the treatment liquid system is already contaminated at the time when it is detected, and the contamination of the foreign matter is not detected. Cannot be prevented.

(3) In order to ensure durability by sliding the piston / cylinder of the booster, it is desirable that the oil has a high viscosity.

However, since the treatment system is contaminated due to the damage of the treatment liquid envelope 5, the one having a low viscosity is used in consideration of the subsequent cleanliness and is not suitable in terms of durability.

[0021]

The gist of the present invention made to solve the above-mentioned problems is as follows.

(1) Having an elastic body inside the container,
A method of pressurizing the treatment liquid inside the envelope by placing the treatment liquid inside the envelope and pressurizing the liquid placed between the inside of the container and the outside of the envelope. Or the liquid contained between the inside of the container and the outside of the envelope is the same, or the liquid is made into pure water and introduced between the inside of the container and the outside of the envelope. A method for pressurizing a liquid, which comprises monitoring the mixing of another liquid that pressurizes the liquid with the liquid.

(2) A container having an elastic body for containing the treatment liquid inside the container, and a pressure booster for pressurizing the liquid contained between the inside of the container and the outside of the container is connected to the container. In a liquid pressure treatment device arranged in a pipe, a container having an elastic body for containing the treatment liquid or pure water therein is arranged between the pressure booster and the container, and the pressure booster is used. A liquid pressure processing apparatus, characterized in that a monitoring means for mixing the liquid of (1) with the processing liquid or pure water is provided.

[0024]

The following effects can be achieved by using the above means.

That is, (1) the liquid to be treated is sealed with an elastic body such as rubber,
As a medium for pressurizing the sealed body, a liquid which is the same as the liquid to be treated or which does not impair the cleanliness is used, so that even if the sealed body is damaged, the liquid to be treated is not contaminated.

(2) The secondary pressurizing medium for pressurizing the liquid to be treated is sealed by the secondary pressurizing medium encapsulant 18, and the minimum volume that the secondary pressurizing medium encapsulant 18 should have is
The sum of the volume of the secondary pressurizing medium 4, the processing liquid envelope 5, and the volume in the piping system, which is the total amount of liquid contraction until the required pressurization and the amount of expansion of each container, pipe, etc. until the required pressurization. Yes, for example, in the case of seawater and oil of this example, the amount is about 5% of the sum of the volume of the secondary pressurizing medium 4 and the volume of the treatment liquid envelope 5.

Therefore, the volume of the secondary pressurized medium encapsulant 18 is
The required pressure effect can be achieved with an extremely small amount.

In this case, even if the secondary pressurized medium sealing body 18 is damaged and oil of the pressure booster is mixed in, the contaminated area is shut off by the valve 16 and the contaminated area is narrowed. The operation can be started early by a method such as replacement or washing.

(3) Before injecting the secondary pressurized medium 4 into the barrel 7, the valve 16 is closed and the pressurized medium in the secondary pressurized medium tank 28 is placed in the secondary pressurized medium enclosure 18. The secondary pressurizing medium is filled with the pump 27 to fill the secondary pressurizing medium encapsulant 18 and the primary pressurizing medium 17 is pressurized to a predetermined pressure, that is, 100 MPa in this example. After confirming the soundness of the secondary pressurized medium encapsulant 18 by the foreign matter detector 37, the valve 16 can be closed to open and injected into the secondary pressurized medium 4.

Further, the secondary pressurizing medium 4 is monitored by a foreign matter detector 38 different from the above, and when foreign matter is mixed, the valve 16 is closed to almost eliminate the diffusion of contamination. .

Further, since the liquid to be treated is sealed by the treatment liquid encapsulant 5, the treatment liquid system is completely contaminated, and it is a perfect system.

(4) The pressure booster 2 is operated by the system described above.
Since the oil used in the high pressure side pressure chamber 31 of 9 does not contaminate the processing liquid system, the lubricating oil suitable for the high speed and high reciprocating motion of the pressure intensifier can be appropriately used, so that the life of the pressure intensifier is long. Was able to be greatly improved.

[0033]

FIG. 1 shows an embodiment of the present invention.

The volume of the treatment liquid tank 1 is 0.5 m ³ , and 0.4 m ³ of the deep-sea bacterium pressure culture medium, that is, the treatment liquid is contained therein, and the treatment number of 4 times is stored. .

The processing liquid is injected into the processing liquid sealing body 5 by the pump 2 through the valve 3 and the processing liquid inlet / outlet 12.

At the same time, the secondary pressure medium 4 is also injected. At this time, the valve 13 is closed.

As described above, the processing liquid and the secondary pressurizing medium 4
When each of the cylinders 7 is filled with liquid, the treatment liquid envelope 5 is filled with liquid and is in a state of being sandwiched as shown in FIG.

Here, the secondary pressurizing medium 4 includes a body 7, a top cover 6,
The total volume of the secondary pressurizing medium 4 volume 0.1 m ³ and the processing liquid sealing body 5 volume 0.1 m ³ is 0.2 m ³ which is maintained by the lower lid 11 and the seal 10.

The treatment liquid seal 5 is attached to the tip of the protruding pipe of the treatment liquid inlet / outlet 12 by a seal 8 as shown in the figure.

On the other hand, before injecting the secondary pressure medium 4 into the barrel 7, the following operation is performed.

That is, the high-viscosity oil in the low-pressure liquid tank 35 is passed through the low-pressure liquid inlet / outlet 30 by the pump 34, and the pressure booster 2
When entering the low-pressure side pressure chamber 32 of No. 9, the high-viscosity oil in the high-pressure side pressure chamber 31 which has been increased in pressure to 100 MPa in the high-pressure side pressure chamber 31 has a check valve 33, a primary pressurizing medium inlet / outlet port. It is injected via 24 into the primary pressurized medium 17.

At the same time, pure water is stored in the secondary pressurized medium tank 28, and the volume in this example is
Although it is 0.1 m ³ , this pure water, that is, the secondary pressurized medium is supplied to the valve 26, the secondary pressurized medium inlet / outlet 2 by the pump 27.
2 and is injected into the secondary pressurized medium encapsulant 18.

At this point, the valves 25 and 16 are closed.

The state in which the primary pressurizing medium 17 and the secondary pressurizing medium have been injected and filled up is the state shown in FIG. 1, and the valve 26 is closed in this state.

In order to maintain the pressure of the primary pressure medium 17, the cylinder 1
A container is constituted by 9, the upper lid 20, the lower lid 23, the seal 21, and the like, and the inner volume of the solution, that is, the volume of the primary pressurized medium 17 of 0.03 m ³ and the secondary pressurized medium sealing body 18 the sum of the volume of 0.02m ³ is a 0.05m ^3.

Valve 36, valve 26, valve 16, valve 25, valve 40
When the pressure booster 29 is continuously operated with the
When the pressure of the primary pressurizing medium 17 is increased to 100 MPa, the operation of the booster 29 is stopped.

When the pressure of the primary pressurizing medium 17 is increased to 100 MPa, the secondary pressurizing medium in the secondary pressurizing medium encapsulant 18 also becomes 100 MPa.

At this time, it is confirmed by the foreign matter detector 37 that foreign matter is not mixed in due to damage to the secondary pressurizing medium encapsulation body 18, and if there is no abnormality, the valve 40, which has been open until now, is closed.

Then, the valves 16 and 26 are opened, and the secondary pressurized medium in the secondary pressurized medium tank 28, that is, pure water is injected into the barrel 7 by the pump 27, and the secondary pressurized medium is injected. After the medium 4 is filled with the liquid, the pump 27 is stopped and the valve 26 is closed.

Thereafter, the valve 40 is opened and the pressure booster 2
9 is operated again, and the pressure of 100 MPa is applied to the secondary pressurized medium enclosure.
Keep calling. If foreign matter is detected to be mixed in at this point, the valve 16 is closed.

The pressure is transmitted to the secondary pressurizing medium 4 in the body 7, and the treatment liquid encapsulant 5 is compressed to 100 M while compressing the liquid.
Pressurize at Pa and pressurize the treatment liquid.

For a fixed time, in this example, 1 minute, 100M
After being pressurized at Pa, the valve 1 is closed with the valve 16 closed.
3 is opened and the treated liquid is injected into the treated liquid tank 14.

During these series of operations, the foreign matter detectors 37, 38 and 39 monitor the respective liquids to ensure the soundness.

Since the processing liquid inlet / outlet pipe and the like that come into contact with the processing liquid are required to have high cleanliness and poisoning,
Titanium alloy is used as the material, and the materials such as seal and rubber all have the same properties.

[0055]

As described above, according to the present invention, the above problems can be solved.

As a result, (1) when pressure is applied to the treatment liquid, it is possible to completely prevent mixing of oil or the like on the pressure intensifier side during pressurization, and to stably improve productivity. (2) Furthermore, since a high-viscosity lubricating oil that is optimal for the pressure booster can be used, the life of the pressure booster can be greatly extended.

[Brief description of drawings]

FIG. 1 is an explanatory diagram showing an embodiment of the present invention.

FIG. 2 is an explanatory diagram showing an example of a conventional method.

[Explanation of symbols]

 1 Treatment Liquid Tank 2 Pump 3 Valve 4 Secondary Pressurized Medium 5 Treatment Liquid Enclosure 6 Upper Lid 7 Body 8 Seal 9 Secondary Pressurized Medium Inlet / Outlet 10 Seal 11 Lower Lid 12 Treatment Liquid Inlet 13 Valve 14 Treated Liquid Tank 15 Valve 16 Valve 17 Primary pressurized medium 18 Secondary pressurized medium Enclosure 19 Body 20 Upper lid 21 Seal 22 Secondary pressurized medium inlet / outlet 23 Lower lid 24 Primary pressurized medium inlet / outlet 25 Valve 26 Valve 27 Pump 28 Secondary pressurized medium Tank 29 Pressure booster 30 Low pressure liquid inlet / outlet 31 High pressure side pressure chamber 32 Low pressure side pressure chamber 33 Check valve 34 Low pressure pump 35 Low pressure liquid tank 36 Valve 37 Foreign matter detector 38 Foreign matter detector 39 Foreign matter detector 40 Valve

─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. ⁵ Identification number Internal reference number FI Technical indication C12M 1/00 C C12N 1/00 B 7236-4B (72) Inventor Hitoshi Kinugasa Sagara, Harahara-gun, Shizuoka Town Goddess 21 Itoen Central Research Institute Co., Ltd. (72) Inventor Taichi Takeo Sagara-gun, Shizuoka Prefecture Goddess 21 Itoen Central Research Institute

Claims (2)

[Claims] 1. A container having an elastic body inside the container, wherein the treatment liquid is placed inside the container and the liquid contained between the inside of the container and the outside of the container is pressurized to press the liquid. In the method of pressurizing the treatment liquid inside the envelope, the treatment liquid inside the envelope is the same as the liquid placed between the inside of the container and the outside of the envelope, or the liquid is pure water. In addition, the method for pressurizing a liquid is characterized in that the liquid contained between the inside of the container and the outside of the envelope is monitored for mixing with another liquid that pressurizes the liquid. 2. A pipe having an elastic body for containing a treatment liquid inside the container and connecting a pressure booster for pressurizing the liquid contained between the inside of the container and the outside of the container to the container. In the liquid pressure treatment apparatus disposed in, a container having an elastic body for containing the treatment liquid or pure water therein is disposed between the pressure booster and the container, and the pressure booster is used for the pressure booster. A liquid pressure treatment apparatus, characterized in that a monitoring means for mixing the liquid with the treatment liquid or pure water is provided.