JPH06181984A - Bag to store concentrate - Google Patents

Abstract

PURPOSE: To obtain bags for accommodating the solids or condensed fluids to be used for preparing a dialysis fluid by using a dialysis system. CONSTITUTION: This bag has its main body and at least one opening. This opening is surrounded so that it is sealed off by a plug component 220 that forms a flow connection with the bag inside in a state of connecting it to a second plug component 210. The plug component 220 has the connectors 276, 268 suitable for being connected to the second mutually-complementary plug component 210 to be arranged on the dialysis system. The first flow route is formed into the bag from the dialysis system in the connection state made by the plug connectors. The second flow route is formed for returning the dialysis fluid from the bag's inside into the dialysis system. This invention also associates with fitting the plug connectors, sockets and tubes, all to be used together with the bags.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION This invention relates to the preparation of dialysis fluid using a dialyzer having a bag body, at least one opening, and in addition a plug-type connector for use with such a bag. A bag for containing a solid or fluid concentrate for packaging.

[0002]

2. Description of the Prior Art Usually, with hemodialyzers used today, the concentrates used for the preparation of dialysis fluid are prepared in the factory and transported in the canister to the user. Both the preparation and transportation of such a canister filled with fluid concentrate is expensive. The reason is that in fact, only water is transported from the manufacturer to the patient, and an empty canister presents an environmental problem. Of particular concern is the storage and transportation of canisters filled with bicarbonate concentrates. This is because the canister swells due to the release of carbon dioxide and becomes in an overpressure state. Thus, the problem of explosion when the canister is improperly handled is in such a swollen container.

Therefore, clinical systems have been proposed which have a ready-to-use dialysis fluid made available or a powdery concentrate, especially a bicarbonate concentrate, mixed with water.

The first type of system comprises a centrally known central dialysis fluid supply system, which supplies dialysis fluid in a circuit, especially for a plurality of dialysis machines in a hospital.

On the other hand, a powdered concentrate is also supplied, which is connected via a pipe system with a dialysis machine on one side and on the other hand via a water source and a water line. Fresh bicarbonate concentrate is made available online with such a system that can be fed directly to the dialysis machine without significant emission of carbon gas. Such a system is described, for example, in EP A1-0,278,100 and
A1-443,324.

Since such containers must be replaced frequently, simple attachment and removal of such containers using a coupling system is convenient. However, such a system is not described in the two European patents mentioned.

Furthermore, a dialysis machine, which can be connected with various concentrate or dialysis fluid supply arrangements, for example in a simple connection arrangement, connects the dialysis machine from the central supply device to the bag containing bicarbonate powder. It is convenient to be possible.

[0008]

It is an object of the present invention to provide a simple and safe device for the preparation of dialysis fluid from a solid and / or fluid concentrate source, whereby a dialysis machine is provided. The transport of concentrate used is reduced to a minimum.

Another object of the present invention is to provide a plug connector in which the device is easy and safe to handle for various concentrate sources.

[0010]

With respect to this device, its object is achieved by the combination of the features of claim 1.
Dependent claims 2 to 11 show additional useful designs of the bag according to the invention. Regarding the plug-type connector, its purpose is claim 12.
Achieved by a combination of thirty to thirty features.

For plug-in connectors, in particular for the plug components on the side of the device of the second embodiment, the priority of German utility model G 92 17 989.4 is claimed.

The bag of the present invention is usually made of, for example, PVC, PV.
It is made of a flexible material such as P or polyethylene. The plug-type connector, which is arranged directly on the body of the bag, ie on the wall of the bag, replaces the conventional conventional hose connection between the dialysis machine and the container of concentrate. Therefore, the duct passage is successfully shortened. The bag is easily replaced by the plug-in connector and clamps securely on the dialysis machine.

The particular advantage of the bag of the invention in which the container of concentrate which allows the inflow of water and the withdrawal of the diluted concentrate is connected to the dialysis machine by a single connection must be considered.

It is preferred that the incoming water be full, with the concentrate being diluted if the incoming fluid is directed through the tube to the inside of the bag body. The possibly diluted concentrate is led to the dialysis machine via a tube which projects inside the bag and which has a filter on its suction end. The inflow and outflow solution flow passages can be arranged parallel or concentrically with the plug connector. It is also advantageous if the intake and outlet are arranged in parallel on the plug components on the sides of the bag, with a concentric arrangement of the flow passages in the plug structure.

In the preferred embodiment, the bag of the present invention has a marking on its plug component that characterizes the contents of the individual bag in each case. It is thus ensured that the correct concentrate container is always connected to the correct fluid line of the dialysis machine. It is preferably covered by a locking cap until use to prevent damage or contamination of the bag side plug components during shipping.

The plug connector of the present invention is distinguished by a group of significant advantages. It is possible to provide different working conditions for the plug-type connector by means of a valve element which is movably integrated in the valve chamber of the socket body. Thus, for example, the fluid supply channel and the outlet channel are short-circuited in the closed position of the plug component on the side of the second device. The reason is that the movable valve element is pushed by the preloaded compression spring towards the input side of the second plug component, ie towards the side of the first bag side where the plug component is mounted. Because. In contrast, when the bladder is installed, the valve element is separated from the input side against the pressure of the spring. Thus, according to the present invention, when the concentrate container is installed, the first and second flow passages are sealed from each other by the arrangement of the sealing means.

To completely sterilize the second plug component before using the concentrate container, a cleaning cap, such as a cap that pushes from the inlet side against the stress of the spring, is
Can be slid onto the plug component on the side of the device. In the cleaning cap, the first and second flow passages are short-circuited to ensure complete cleaning and sterilization of the second plug component.

According to another embodiment of the present invention, the second plug component has an additional fluid inlet channel that can be connected to an additional concentrate container. However, this second inlet channel is connected to the valve chamber only when the movable valve element is in the closed position. When the bladder is attached, this second inlet channel is sealed from the valve chamber by the sealing means attached to the valve element.
It is thus ensured that in each case only one concentrate container is connected to the dialysis fluid circuit via the plug connector.

This socket thus makes it possible to design a dialysis machine which can be used in all cases, whereby very different supply systems can be connected by means of only one plug-type connector. This leads to a reduction in the cost of the device. Furthermore, it is very convenient that there is only one socket that has to be cleaned and serviced.

The pluggable connector of the present invention is such that both the intake and outlet channels respectively open from outside the wall of the socket body into the valve chamber and depending on the position of the movable valve element the flow passages are short circuited or mutually closed. Designed to be separated from. However, according to a second embodiment of the present invention, a sealing liner can be introduced into the valve chamber and then the second plug component allows the channel to extend through the socket body and the sealing liner. And is designed to empty the valve chamber through an opening in the sealing liner. Again, in this embodiment the position of the valve element has little effect on either the shorting or the separation of the two fluid passages.

The valve element can be made in one piece with the shank element against which the compression spring is placed. Alternatively, the valve element can be moved by a push rod connected to the shank element.

In the sealing arrangement of the invention, engaging the sealing means provided in each case by moving the valve element to a position determined by the plug component on the side of the first bag, It can be very simple to have the automatic switching of the plug components on the side of the device with the insertion of the plug components on the side of the bag. When the bag is not attached, the valve element is carried to its closed position by a resilient element, preferably a compression spring.

The sealing means are spaced apart and in each case are inserted into the channels of the ring, at least two.
Either one O-ring or at least one movable O-ring is provided, whereby the O-ring is in each case engaged with the cylindrical region of the valve element. By these sealing means, the plug component on the side of the device is tightly sealed against the inlet side in the closed position when the bag is attached, while at the same time effectively separating the two flow passages.

Furthermore, a valve chamber extending between the valve element and the end part of the plug component on the device side facing the inlet side is provided with two partial compartments with respect to the elastic element by means of an elastic wall. It may be expedient if it is divided into two parts, whereby one sub-chamber accommodates the elastic element and the other sub-chamber provides fluid uptake. In this way, contamination of the elastic elements or of the fluid is prevented and the cleaning of the connecting liners is considerably simplified. Via the plug arrangement according to the invention, the dialysis machine can not only be connected to a bag with a solid or fluid concentrate, but also for example with a central concentrate supply. Water or an aqueous solution can be used as a solution; however, only water is described below.

Since only one flow channel is required, the plug for connecting to the central concentrate supply can be designed like a simple plug in the form of a tube. However, the concentrate can also be connected via the second supply line of the second plug component provided in the preferred embodiment of the invention.

With the double-concentrate concentrate plug, the water supplied to the plug connector and bag is first introduced into a solid or fluid concentrate, such as bicarbonate powder, and then the dissolved concentrate, For example, saturated bicarbonate solution is
It returns through the connector and is sent to the dialysis machine. The line of tubing that can be used, i.e. the tubing line between the plug connector and the dialysis machine, can be designed concentrically, i.e. with inner and outer tubing, or with two parallel channels. You can do it.

[0027]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT An embodiment of a plug component will be described below with reference to FIGS. The plug connector has first and second plug components by which the first plug component is connected to a bag of concentrate (plug component on the side of the bag); second plug component The (plug component or coupling socket on the side of the device) is placed on the dialysis machine.

Initially, the plug component has a second device-side plug component located on the dialysis machine, described below as coupling socket 10. Coupling socket 10
Has a socket body 12 with a generally cylindrical recess 14 extending over a portion of the length of the socket body 12 having different diameters in small areas.

Behind its free insertion end 16 facing the inlet side, the recess 14 has a channel 18 forming part of a click-stop means, as will be explained below. Fix the connector 20 on the bag side at the position. Furthermore, the sealing ring 22 is conveniently arranged inside the recess 14 and seals the side plug of the bag while being connected to the surroundings.

A valve chamber 26 having a relatively large diameter is provided in the central portion 24 of the recess 14 and an elastic wall 28 extends perpendicularly to the main axis of the socket body 12. For this purpose, the socket body 12 is divided into two socket parts 30 and 32,
As a result, the wall 28 can be extended into the joint 34 by bolts 36, as seen in FIG. Therefore wall 28 is a wall
Valve chamber whose volume can be changed by moving 28
Is divided into a left half 38 of the compartment and a right half 40 of the compartment.

The outlet channel 42, which can be connected to the dialysis fluid system (not shown) of the dialysis machine, is located in the left half of the compartment.
It's out of 38. Half of this valve chamber on the other side
38 couples the flow via a cylindrical recess 14 with an inlet channel 44 opening into the recess 14 in a region 45 delimiting the half 38 of the valve chamber.

As can be seen in FIGS. 1 to 3, on both sides of the inlet channel 44 ring-shaped sealing arrangements 46, 48 are arranged in each case in the form of O-rings.

Furthermore, the valve element 50 is arranged in the recess 14 with a cylindrical end region 52 towards the back, the element 50 and the end region 52 being separated from each other by a flexible wall 28. . The valve element 50 itself has a generally cylindrical front surface region 54 and a conical region 56 tapering inward. The conical region 56 bears against its ends an elastic element 60 in the form of a spring, which spring is located in the end region of the recess 14.
It is joined by a shank 58 which is arranged at 62 and which forms a cylindrical end region 52. Attached to the end of the shank 58 is a magnet 64 that works in conjunction with a reed switch 66 located in the portion 32, which magnet 64 and reed switch.
66 forms a sensor 68 with which the bonding process can be monitored.

FIG. 1 shows a working condition in which the plug 20 on the side of the bag is not visible in the recess 14. That is, the spring 60 causes the valve element 50 to be preloaded further to the left than is possible with the stop 70 surrounding the shank 58 which is clamped against the compartment of the right half 40 of the compartment. Thus, the cylindrical front area 54 of the valve element 50 is in sealing contact with the left ring type sealing arrangement 46, closing the inlet channel 44 to the surroundings. This position is called the closed position.

On the other hand, because of the conical arrangement of the conical areas 56, a ring-shaped space is created in the area of the inlet channel 44 and a flow connection with the outlet channel 42 is provided to the left of this ring-shaped space and the valve chamber. Made through half 38. Therefore,
It is possible to wash the coupling socket 10 and the dialysis machine with water or a germicidal solvent.

FIG. 2 shows that the plug 72 on the side of the bag shown in FIG.
The actuated state in which the pawl means 74 arranged on 72 is engaged with the pawl recess 18 is shown. According to the embodiment shown in FIG. 5, the plug 72 on the side of the bag is designed with a double guide hole and opens towards the rear handle part 79, between which a ring-shaped channel 80 is provided. An inner tube 76 and an outer tube 78, in which is formed. This ring-shaped channel 80 has a front recess 82 penetrating the outer surface of an outer tube 78 which successfully surrounds the end of the first plug component 72 facing the ring-shaped coupling socket 12. Have. At the handle portion 79, the tube 80 opens towards the first feed opening 84.

A central channel 86 exiting from the front end 88 through an opening 90 whose end faces the socket body 12.
Pass through the inner tube 76 and open in the handle portion 79 towards the opening 92.

As shown in FIG. 2, in the connected state, water passes from the duct 44 through the opening 82, the channel 80, the opening 84 (see FIG. 5), the channel 96, and then the filter 102 to the bag 100.
Flow to where the bicarbonate can be dissolved. For the sealed bag 100, the bicarbonate solution is
And the channel 98, back to the plug 72, through the openings 92 and 90 in the channel 86, from which it flows into the outlet channel 42 (FIG. 5).
Reach). This results in a circuit through the connector arrangement of the present invention, thereby mixing water with bicarbonate,
Further prepare the bicarbonate concentrate.

The front end 88 surrounding the ring-shaped opening 90 is
... as seen particularly in Figures 1, 4, and 5 ... valve element 50
It is engaged with a plurality of protrusions 108 arranged in an upper circle. Thus, fluid can flow through the valve element 50 into the left half 38 of the compartment between the protrusions 108 when the plug is engaged.

Further, FIGS. 1, 2 and 5 show that the plug 72 in the connected state is in flow communication with the inlet channel 44 through the opening 82, resulting in two ring-shaped closures on both sides above the opening 82. Configurations 46 and 48 are shown sealing outer tube 78. On the other side, the front opening 90 of the plug 72 is on the far side of the innermost ring-type closure arrangement 48 on the side of the left half 38 of the compartment and is therefore in flow connection with the opening 82. Not directly (only possible via the bag 100).

FIG. 2 also shows schematically that the magnet 64 in the connected state can actuate the reed switch 66 and thus the sensor 68 to ascertain the easily operatively mounted position of the plug 72.

FIG. 3 shows the operating condition with the plug component 110 inserted in the coupling socket 10. The plug element 110 is made solely of a tube 112 and additionally has a grip element 114 for engaging the grip channel 18. The plug component 110 is dimensioned so that it further extends beyond the innermost ring-shaped sealing configuration 48 in the mated condition and, in addition, works with the protrusion 108 of the valve element 50 to Move 50 back towards spring 60. Accordingly, the opener front opening 116 is also in flow communication with the outlet channel 42. The other end 118 can be connected to the concentrator via a hose or tube (not shown). In this case, the water source is (inlet channel 44
Closed).

Furthermore, FIG. 3 shows that a central axially projecting projection 120 is arranged on the valve element 50, which extends in a joined state without completely sealing the opening 116. And also shows the opening of a check valve 122 located therein and located in the tube 112.

Also in FIG. 3, the sensor arrangement 68 has been actuated in a manner similar to the operating condition of FIG.
An operatively fast installation of 0 is signaled after perfect coupling and locking.

In accordance with another exemplary embodiment of the present invention shown in FIGS. 6-8, a flexible bag having bicarbonate powder is replaced by a suitable first plug component to a second plug component. Connectable so that fluid is supplied to the bag,
It is claimed that the bicarbonate is removed therefrom via the plug component. The structure of the socket body and the valve chamber, in particular the right half of the valve chamber with the control element, is similar to the embodiment of the invention described above. As a result, the difference between the embodiment of FIGS. 1 to 5 and the input part of the first plug component, as well as the second plug component, will be explained below. The inlet portion 230 of the socket body 212 is the first plug component 22 of the bicarbonate bag 200 to which it is attached.
Face 0. This side is referred to below as the inlet side 216. The outlet portion 232 of the socket body 212 connects on one side with the inlet portion 230 of the socket body; the channels 244a and 242 have opposite faces 20 which will be referred to as outlet sides below.
There is an opening in 5.

At the inlet portion 230, the sealing liner 209 and valve liner 250 are mounted. The sealing liner is mounted immovably. It is the inflow channel 244
Central hole 244c extending in the longitudinal direction as a continuation of a and b
Have. From the central hole 244c, a connecting channel 244b extends to the channel portion 244a, whereby the channel portion 244a is incorporated into the wall of the socket body 212. In this way, a perfect fluid connection is obtained from face 205 to sealing liner 209.
Made all the way across the central hole 244c. The portion of the central hole 244c between the channel portion 244b and the end of the sealing liner 209 is sealed by the sealing stop 211. The end of the central hole facing the inlet side opens into a lateral hole 213 extending parallel to the inlet side 216. Face 215 terminates in a sealing liner 209 on the inlet side.

A sealing liner 209 is formed on its end facing the outlet side 205 and fits sealingly within the hole 214. An O-ring 207 is inserted between the backing in the socket body 212 for a secure seal. Hole 21
Between the outlet of the channel 242 and the inlet side 216 for discharging the fluid to 4, the diameter of the sealing liner 209 is significantly reduced. Sealing liner and socket body entrance 230
The intermediate space created in the valve chamber 226 between and is filled so as to be partially sealed by a movably arranged valve element, namely a cylinder-type valve sleeve 250.

Similarly, valve sleeve 250 has portions of various diameters. The first ring-shaped portion 217 extends from the inlet side into the hole 214. This portion has a much smaller diameter than the hole 214. The surface of the portion 217 facing the inlet side serves as a stop surface 219 for the bag side plug components. The first ring-shaped portion 217 follows on the side remote from the stop surface 219 by a ring-shaped portion 221 which is sealingly inserted in the hole 214. An O-ring 22 inserted into the socket body between this portion 221 and the socket body 230
2 tightly seals the device side plug component 210 to the outside. The third ring-shaped part 223 is the outer part
Form the end of the valve backing 250 facing 232.
The diameter of this portion 223 is chosen so that it fits snugly into the corresponding clearance within the aperture 214. In contrast to the embodiment described in FIGS. 1 to 4, here a valve element
The 250 is not designed as one piece that leans on the spring. Instead, the spring force is now transmitted to the valve element 50 via the magnetic liner 252 and the stop 254. valve·
The liner 250 is installed with appropriate play on the sealing liner 209 so that it can be moved without difficulty, leaving more room for the passage of fluid.
The thickened portion 225 of the valve liner 250 fits snugly with the sealing liner 209 only in the respective regions of the first and / or second ring-shaped portions 217, 221 of the valve liner 250. Extend. In the area of the thickened section 225, the sealing liner 209 has an O-ring 247 movable therein.
Are disposed in the recess 227 and are guided in the recess 227 by the thickened portion 225 of the O-ring. The lateral holes 213 open in the region of the recess 227. A region 245 in which the valve element 250 extends movably supplies or exits fluid until a secure sealing of the second plug part to the outside is ensured in the closed position and when the bladder is installed. It extends until the passages are safely separated. Valve liner
250 has a radial bore 229 extending in the third ring-shaped portion 223 parallel to the intake side.

Moving the valve liner 250 actuates control components located in the outlet portion 232 of the socket body. Movement is accomplished either by connecting bicarbonate bags or by mounting a locking cap (not shown) in which the two flow passages (for supply and outlet) are shorted. locking·
The cap is attached to allow complete sterilization of the second plug component 212.

By inserting the sealing liner 209 into the valve chamber, the movable valve element 250 is not integrally connected with the control components of the right half valve chamber. Here, actuation occurs by a stop 254 that is associated with the new magnetic liner 252. The stop is screwed onto the magnetic liner, while at the same time the elastic wall 228 is fixed in the center of the hole 214 in this screwed region. In the area of screw fastening to the magnetic liner, the fastener 254 has the same outer diameter as the liner. The second part of the fastener with the smaller diameter is the inlet part 23, as can be seen especially in FIG.
Extends outwardly from the portion 232 of the socket body into the 0.
The second portion of the stop 254 is made up of two arcuate portions extending as fork-shaped arms 239 through suitable recesses in the sealing liner 209. The fork arm 239 is guided into the recess of the sealing liner, but the fork arm extends beyond the diameter of the sealing liner 209. They are the face of the valve liner 250 facing the outlet side 205 and the stop surface 24.
Overlapping in 3 areas. Movement is transmitted from valve liner 250 to magnet 264 via stop surface 243.

In the following, the operating mode of the second plug component 210 in the closed position (without the bag) and with the bicarbonate bag attached or with the sealing cap will be described.

FIG. 6 shows a second plug configuration of the invention with the bicarbonate bag not attached and the locking cap not attached for sterilization of the second plug component. Element 210 is shown. In this position, the preloaded compression spring 260 pushes the magnetic liner 252 against the induction liner 231. In this position it experiences a maximum distance of travel into the inlet portion 230 of the socket body because the stop 254 is rigidly coupled to the magnetic liner 252. Therefore, the valve liner 250 is also maximally pushed toward the inlet side by the stop surface 243. O-ring 247 at this position
Is fixed between the thickened portion 225 of the valve liner 250 and the inlet side boundary of the recess 227 of the sealing liner 209. Thus, the passage of fluid between the sealing liner 209 and the valve liner 250 is effectively sealed to the outside.
At the same time, the second portion 221 of the valve liner 250 is installed in a sealing manner against the O-ring 222 that is inserted into the socket body 230. Therefore, the passage of fluid between the valve liner 250 and the socket body 230 is also impossible.

At this position, the second plug component 210 can be rinsed. The opposite end of the central hole 244c is the sealing stopper 21.
Fluid inlet channel 24 as it is sealed by 1.
As indicated by the direction of the arrow at the entrance of 4a, water or sterilizing solution flows through channel 244 and into central bore 244c, from which fluid flows through lateral bore 213 to the sealing liner and valve liner. It flows into the space between. Also through the radial holes 229, the fluid reaches the space between the valve liner and the socket body. This ensures that no play space is created and that the second plug component 210 is perfectly flushed. The water or germicidal solution is then removed through channel 242 to drain the fluid.

FIG. 7 shows the position of the movable element of the second plug component when the bicarbonate bag is mounted on the inlet side of the mating socket. The plug 220 is directly connected to the bicarbonate bag 200 without the intermediate tube.
The second plug component 210 and the plug 220 are fixedly connected to each other by a notch latch 237. The notch latch 237 is movably mounted by a pivot 249 on the mating socket and the notch 235 plugs the plug 220.
It is attached to the fixing protrusion 274 of. Bicarbonate bag 200
On the side away from, the plug 220 has three concentric ring walls. The first, outer ring wall 251 supports the locking projection 274 and surrounds a portion of the socket body 230. This outer ring wall 251 is the ring wall projecting farthest.

The ring wall 278 is installed rearwardly in relation to the outer ring wall that sealingly engages the ring seal 222 that is inserted into the socket body 230. Inner ring wall
276 is set further back in relation to the central ring wall 278. When the plug is in the insertion position, the plug component 210
The surface 253 of the inner ring wall that faces the bottom leans against the surface of the valve liner 250 that faces the inlet side. Therefore plug 220
The insertion of the face 253 against the valve liner 250 causes the latter to move against the pressure on the outlet side of the second plug component 210 of the spring 260. When the plug 220 is fixed on the second plug component 210 by the fixing protrusion 274, the ring sealing body 247 also changes into the recess 22.
It is moved by the movement of the valve liner 250, which is influenced by the inner ring wall surface 253, from the 7 inlet side boundary to the outlet side boundary opposite the recess 227. Therefore, the water flowing through the feed channel 244a to the central hole 244c flows through the lateral hole 213 from the second plug component 210,
An inner ring wall 276, which is sealed to the second plug component 210 by an O-ring 247 and which has an outlet 280 through which water leaving the lateral bore 213 can flow out to the inside of the bag 200. Enter the intermediate space surrounded by. The concentrated bicarbonate solution produced in bag 200 is absorbed via inlet line 286 with a filter (not shown) on its inlet end. Entrance line 28
6 opens towards a circular intermediate space between the inner ring wall 276 and the central ring wall 278. Mixing of the bicarbonate solution with the incoming water is not possible because the communication between the two spaces is blocked by the ring-shaped encapsulation 247. Incoming bicarbonate solution exits the space between the inner and central ring walls and enters the intermediate space between the valve liner 250 and the socket body 230. It is further passed through radial bore 229 to the space between sealing liner 209 and valve liner 250 and through channel 242 to the bicarbonate solution outlet line. It is convenient to place the channel 242 over the feed channel 244 to ensure that any CO ₂ generated is safely released with the bicarbonate solution. The exit of bicarbonate solution from the second plug component 210 is blocked by the central ring wall 278 sealingly engaged with the ring-shaped closure 222. The second embodiment of the invention described here allows a particularly perfect plug connection, which ensures a simple and reliable separation of the two flow passages from one another.

The movement of the magnet 264, ie the mounting of the bladder, reactivates the reed switch 266 with a suitable control device (not shown).

If a locking cap is placed on the inlet side of the socket body 230 for cleaning and sterilization of the second plug component 210, the locking cap will have bags 280 and 286 respectively. It is constructed the same as the Depressing Plug 220 with the difference that it does not open towards the 200, but is instead short circuited. As a result, water or sterilizing solution exits the lateral bore 213, directly into the intermediate space between the inner ring wall 276 and the central ring wall 278 via the short circuit line, and the socket body 230 and valve liner. Flows back through the space between 250 and the sealing liner 209 to the outlet channel 242. Therefore, all surfaces that come into contact with the bicarbonate solution are thoroughly and completely cleaned.

An additional embodiment of the plug connector of the present invention is shown in FIGS. This example not only allows the fluid concentrate to be prepared from a solid in the configuration of the present invention, but also the fluid concentrate can be diluted by itself and the same configuration, and if appropriate multiple concentrates. It should also be considered that a dialysis fluid concentrate can alternatively be prepared. For this purpose, a second plug component
210 has an additional channel 300 in the socket body for adding fluid concentrate. As shown in FIGS. 9 and 10, the channel leads from the outlet side of the socket body 232 to the cavity between the sealing liner 209 and the valve liner 250. The tube 304 is connected to the channel 300 via a port 302 that is inserted into the channel 300.
The flow port 302 is sealed to the socket body 306 by an O-ring 306. Tubing 304 is connected at its opposite end either to a container of concentrate, eg for a highly concentrated bicarbonate solution, or to a dialysis fluid circuit while rinsing the device. Second plug component shown in FIG.
At 210, the concentrate is delivered from a container with a highly concentrated bicarbonate solution into the cavity between the sealing liner 209 and the valve liner 250. If appropriate, dilution water likewise flows via channel 244 and then through lateral hole 213 into the cavity between sealing liner 209 and valve liner 250. A controller (not shown) ensures that a pre-defined mixing ratio is maintained. The diluent fluid then passes through channel 242 to the second
Exit the plug component 210 of the device toward the dialyzer.

When the first plug component 220 is installed, the concentrate channel 300 is positioned on the valve element 250, conveniently on the third circular portion 223.
It is sealed to the valve chamber 226 by rings 308 and 310. O-rings 308, 310 are located on the third circular portion 223 so that they are located on opposite sides of the concentrate channel 300 opening when the bag 200 is in place.

In this mode of use of the second plug component 210, cleaning or sterilization of the mating socket is accomplished by removing the other end of the tube 304 from the canister with a solution of highly concentrated fluid to the dialyzer. Are connected so that water or sterilizing solution flows through both the feed channel 244 and the concentrate channel 300 into the second plug component,
This is done by flushing it completely and then discharging it from channel 242.

According to a preferred embodiment of the present invention, corresponding indicia (not shown) are provided on the outside of the central ring wall 28 and on the second plug component to identify the separate concentrate bags. It can be applied on the inner surface. These indicia may mean, for example, a channel and spring arrangement or a mating ring. They ensure that only bags with a predetermined concentrate can be connected to the connectors and tubing connections provided for them.

[Brief description of drawings]

FIG. 1 is a schematic cross-sectional view of an exemplary embodiment of a second plug component, showing a closed position of the valve element.

2 is a side cross-sectional view of the plug connector of FIG. 1 with the plug of the double guide hole connected to the connector of the bag filled with bicarbonate powder.

FIG. 3 is a view similar to FIGS. 1 and 2 with the plug connected to the connector of the central concentrate supply.

FIG. 4 is a side cross-sectional view of another exemplary embodiment of the second plug component with illustrations of the inlet and outlet channels omitted.

5 is a schematic cross-sectional view of a bicarbonate bladder plug, similar to the plug shown in FIG.

FIG. 6 is a longitudinal cross-sectional view of an embodiment of the second plug component in the closed position.

FIG. 7 is a likewise longitudinal cross-sectional view of an embodiment of a second plug component with the first plug component having an attached bag.

8 is a longitudinal cross-sectional view of the moving element of the second plug component shown in FIGS. 6 and 7 (rotated 90 ° with respect to FIG. 7).

FIG. 9 is a longitudinal cross-sectional view of another embodiment of the second plug component.

FIG. 10 is a view of an example of the second plug component of FIG. 9 with the bag attached.

[Explanation of symbols]

10 ... socket, 12,212,230 ... socket body, 14,227 ... recess, 16,118 ... end, 18,42,44,80,96,242,244,304 ... channel, 20 ... connector, 22 ... ring, 26,226 ... chamber, 28,251,276,278 ... wall, 30,32 ... Socket part, 34
… Joints, 36… Bolts, 46,48… Sealing configurations, 50… Valve elements, 52, 54, 56… Valve areas, 60… Elastic elements, 64, 66
… Switch, 68… Sensor configuration, 70,211,254… Stoppers, 7
2,220 ... Plug, 74 ... Pawl stopping means, 76,78,112 ... Tube, 79 ... Handle part, 80,280 ... Inlet, 82,84,90,92,
116… Openings, 86,286… Outlets, 100,200… Bags, 102… Filters, 110,212… Plug components, 122… Check valves, 20
5,253… face, 207,222,306,308,310… O ring, 209,25
0,252… Liner, 213,214,229… Hole, 216… Side, 217,
221 ... Ring type part, 219 ... Stop surface, 225 ... Thick part,
230… Entrance, 232… Exit, 235… Notch, 237
... Latch, 239 ... Arm, 222, 247 ... Sealing body, 249 ... Pivot, 260 ... Spring, 264 ... Magnet, 274 ... Protrusion, 286
… Entrance line, 302… Mouth.

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Balter Pieper, Federal Republic of Germany, 6364 Florstadt 1, Kirchbeek-Allee 4 (72) Inventor Daniel Weber, France F-47220 Astofol, Lacroix (address) None)

Claims (33)

[Claims] 1. A bag containing a solid or fluid concentrate for the preparation of a dialysis fluid using a dialysis machine having a bag body and at least one opening, wherein the plug component (20,220) is a bag. Located on the opening of the body of the (100,200), the plug component enclosing and sealingly surrounds this opening, whereby the plug component (20,200) in the connected state is in flow connection with the inside of the bag. And is adapted to be coupled to a second complementary plug component (10,210) located in the dialysis machine, the first flow passage from the dialysis machine to the inside of the bag and the dialysis machine from inside the bag. A bag characterized by having coupling means (76,78,276,278) for making a second flow passage back to. 2. A plug component (20,200) located in the opening of the bag (100,200) has an inlet (80,280) for fluid flowing from the dialysis machine and an outlet for diluted concentrate returning to the dialysis machine. 2. The bag according to claim 1, wherein the bag has (86,286), and the inlet and the outlet are respectively connected to tubes projecting inward of the bag. 3. Bag according to claim 2, characterized in that the tube connected to the outlet (86,286) comprises a filter (102) on its free end. 4. The bag according to claim 1, wherein the first and second flow passages are concentrically arranged. 5. A bag according to claim 4, wherein each of the first and second flow passages opens towards an inlet (80,280) and an outlet (86,286) which are also concentrically arranged. 6. A bag according to claim 4, wherein each of the first and second flow passages opens towards an inlet (80,280) and an outlet (86,286) arranged in parallel. 7. The bag according to claim 1, wherein the first and second flow passages are arranged in parallel. 8. Bag according to any one of the preceding claims, characterized in that the plug component (20, 220) has a coding which in each case characterizes the content of the bag which is unique. 9. A plug component (20,220) having a pawl means (74,222) ensuring a leak-free connection with the device-side plug component (10,210). The bag according to any one of items. 10. Bag according to any one of the preceding claims, characterized in that the plug component (20, 220) is covered with a locking cap until the bag is used. 11. Bag according to any one of claims 1 to 10, comprising a solid or fluid concentrate for the preparation of dialysis fluid using a dialysis machine. 12. A first plug component (20,220) is attached to the opening of the bag (100,200) and a second plug component (10,210) is located on the dialysis machine and connected to the dialysis fluid supply line. Two plug components (10,20,210,22
0), the second plug component (10,210) comprises a socket body (12,212), in which a substantially cylindrical recess (14,214) is open towards the periphery. ) Is designed so that the first plug component (20,220) can be inserted therein and is preloaded into the closed position by the elastic element (60,260) within the valve chamber (26,226) therein. The valve element (50,250) is movably arranged and the valve chamber (26,22)
6) is connected to the outlet channel (42,242),
The inlet channel (44,244a, b, c) is connected to the valve element (50,25
The area (4) of the recess (14,214) in which (0) is movable
A plug connector for use in a bag according to any one of claims 1 to 10, characterized in that it is open towards 5,245). 13. A sealing liner (209) through which an inlet channel (244a, b, c) is guided, in which the valve element (250) is movable (245).
) The plug connector according to claim 12, characterized in that it is inserted into a valve chamber (226) which opens towards (1). 14. A sealing means comprises a valve chamber (26,226) and / or a recess (1) in which the valve element is movable.
Plug connector according to claim 12 or 13, characterized in that it is arranged in the area (45,245) of 4,214). 15. A sealing means is arranged to alternately seal between the inlet channel (244c) and the outlet channel (242) depending on the position of the valve element, or the valve element (250). A movable O-ring (247) for sealing the valve chamber (226) between the valve and the sealing liner (209) against the inlet side of the second plug component. 14 plug connector. 16. Sealing means seals the valve chamber (26,226) between the socket body (12,212) and the valve element (50,250) closed to the inlet side of the second plug component. 16. The plug according to claim 14 or 15, further comprising an O-ring (22, 222)
connector. 17. At least one sealing liner (209)
Plug connector according to any one of claims 13 to 15, characterized in that it is sealed against the socket body (12, 212) by one O-ring (207). 18. Sealing means are spaced from one another in the recesses (14,214) or a sealing liner (209).
) On which the inlet channels (44,244) are open between the O-rings and which can be alternately engaged with the valve elements (50,250), respectively, with two O-rings (46,48,221,223) respectively. Claims comprising
14 plug connector. 19. The valve element (50,250) according to claim 12 or 13, characterized in that it comprises its side region (56) facing the valve chamber (26,226) having the smaller diameter. The coupling socket according to item 1. 20. The valve element (50,250) is a valve chamber (2
6,226) with radial holes (2
29) The plug connector according to claim 19, further comprising: 21. The valve element (50,250) has a recess (14,21).
4) side facing or valve actuation means (120)
13. An inlet side comprising:
22. The plug connector according to claim 1. 22. The valve chamber (26,226) has an elastic wall (28,22).
Plug according to any one of claims 12 to 21, characterized in that it is separated from the elastic element (60,260) by 8).
connector. 23. A first plug component (20,220) when at least one encapsulant (22,222) is arranged in the recess (14,214) to couple the two plug components together.
23. Any one of claims 12 to 22, characterized in that
Plug connector as described in section. 24. Plug connector according to any one of claims 12 to 23, characterized by sensor means (68) for determining the position of the valve element (50,250). 25. Plug connector according to any one of claims 12 to 24, characterized by pawl means (18) for locking the first plug component (20) in the recess (14). . 26. A complementary cap is mounted on its inlet side for cleaning the second plug component, the cap moving the valve element (50,250) from the closed position,
26. Plug connector according to any one of claims 12 to 25, whereby the first and second flow passages are short-circuited. 27. The second plug component (10,210) comprises:
A plug connector according to any one of claims 1 to 26, characterized in that it has a code corresponding in each case to the code of the first plug component (20, 220). 28. A second inlet channel (300) opens towards the valve chamber (26,226), which channel is either an additional concentrate container or a dialysis fluid circuit, depending on the operating conditions. The plug connector according to any one of claims 12 to 27, characterized in that the plug connector is coupled to the plug connector. 29. Sealing means (308,310) for mounting the second inlet channel (300) on the valve element (250) when the first and second plug components are joined together.
29. Plug connector according to claim 28, characterized in that it is sealed to the valve chamber (226) by means of a. 30. A valve element (50,250), wherein the valve chamber (26,226) is sealed against the inlet side of the recess (14,214), but at least one inlet channel (44,244,30).
0) and the outlet channel (42.242) to the first position, and the inlet channel (44,244a, b, c) also has a valve chamber (26,226) with a recess (14,214) and an outlet channel (42,242). Connected to the first plug component (2
30. Plug connector according to any one of claims 12 to 29, characterized in that the channel (0,220) can be brought to a second position which is open towards the valve chamber (26,226). 31. The valve element comprises an inlet channel (44).
One of the plugs (20) that are locked and have the shape of a tube
30. Plug connector according to any one of claims 12 to 29, characterized in that one channel can be brought to a position open to a valve chamber (26) which is connected to an outlet channel (42). 32. A generally cylindrical recess opening into the socket body is designed to open to the periphery, and flows between the dialysis fluid and the dialysis fluid tube of the hemodialysis machine in the valve chamber therein. The application of a socket in which the valve element is movably arranged to create a passage and is preloaded by the elastic element towards the closed position. 33. Located longitudinally of the plug, on its front end having a first opening on the inlet channel and on its rear end having a second opening to the first guide hole of the tube. A third channel having a first channel connectable to the upper part and penetrating the outer tube of the plug-shaped tube
Laterally connectable radially to a first opening in the opening of the tube, the third opening of which communicates with the outlet channel to open a fourth opening of the tube to the second guide hole. Application of the tube in the form of a plug with a second channel, which forms a flow passage between the dialysis fluid source and the dialysis fluid tube of the hemodialysis machine on its rear end having.