JPH06160727A - Eyeball microscope - Google Patents

Abstract

PURPOSE:To easily execute without an error the alignment of an optical axis of the microscope and an ophthalmic axis against the eyeball surface of an examinee, at the time of executing enlarged observation or enlarged photographing the cornea endotherium of an eyeball of the examinee by the eyeball microscope of a non-contact slit light illumination type. CONSTITUTION:With respect to the eyeball surface 2 of an examinee, a prescribed flickering near infrared ray is radiated from a near infrared ray light emission diode 14 at least through a microscope optical axis 22', and also, a fixed target light is radiated from a visible light emission diode 15 through the optical axis 22' in the same way in order to present a fixed target to the examinee. On the other hand, a front eye part image and an image by the flickering near infrared ray are formed on the CCD photodetecting surface 25 of a video camera 24 and the front eye part image and a light spot by the flickering near infrared ray are displayed on a screen of a monitor 27, and also, the image is allowed to display an alignment circle 28 by a controller 26, and by coincidence of the light spot 29 on the monitor screen by the reflected light of the flickering light from the eyeball surface 2, and the alignment circle 28, the alignment of the optical axis of the microscope is executed.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an improvement of an ocular microscope, and more particularly, to a microscope optical axis and an eye axis of a subject when enlarging observation or taking a photograph of an observed portion such as corneal endothelial cells of the subject. The present invention relates to an eye microscope that facilitates matching with.

[0002]

2. Description of the Related Art Conventionally, in performing non-contact microscopic observation of a surface to be observed such as corneal endothelial cells of the anterior segment of a subject by slit illumination with a microscope, the position of the microscope main body must be adjusted. , In order to put the light radiated from the illumination system to the eyeball into the imaging system which is in a certain relation with the illumination system, it is necessary to align the microscope optical axis with the subject's eye axis, so-called alignment adjustment. There is a problem that the operation is difficult because it is performed in the state. In order to facilitate this operation, the fixation target is projected onto the ocular surface of the eye and infrared light is emitted as alignment light, and a part of the optical axis of the fixation target projection system and an image receiving optical system for reflected light of infrared light are received. Is positioned coaxially with the optical axis of, and the light spot due to the reflected light from the eye spherical surface of the infrared light and the anterior segment image of the subject are displayed on the monitor so that the anterior segment image is displayed. An alignment circle, which is a reticle that has been positioned, is used to position the light spot on the eye axis for alignment with the eyeball, enabling accurate alignment adjustment in a short time. It is shown in the ophthalmologic apparatus of Japanese Patent No. 283352.

[0003]

However, when performing position adjustment of the microscope main body with respect to the subject's eye axis, that is, alignment adjustment, a position adjustment reticle such as an alignment circle of the anterior segment image displayed on the monitor is used. When positioning the light spot of infrared light, which is the alignment light, on the eye axis, other light spots due to unexpected reflection may be displayed on the monitor screen, making it difficult to distinguish them. When the light spot is brought into the position adjustment reticle such as a circle, there is a problem that it may be mistaken for other light spots to cause an adjustment error. It was

The present invention has been made in view of the above points, and eliminates a misalignment between the eye axis and the optical axis of the microscope main body with respect to the eye spherical surface at the time of alignment adjustment and makes it easy to align them. It is an object to provide a contact type slit light illumination type eye microscope. Further, it is another object of the present invention to provide an eyeball microscope of this kind capable of automatically aligning the optical axis of the microscope with the spherical surface of the eye.

[0005]

In order to achieve the above object, in the present invention, an eyeball microscope configured to magnify or photograph a corneal endothelial cell in an observed portion of an eyeball of a subject. As a means for illuminating the subject's eye spherical surface with a predetermined infrared blinking light through at least the optical axis of the subject together with a means for illuminating the fixation target light, the image of the anterior segment of the eye illuminated is displayed on the observation surface. An anterior segment image display unit and an alignment circle display unit that displays an alignment circle on the anterior segment image, thereby aligning with the light spot by the blinking light reflected from the eye spherical surface of the subject on the observation surface. It is configured so that the position of the optical axis of the microscope is aligned with the circle of the eye by matching the circle.

In the above-mentioned eye microscope, a sensor for detecting that the reflected light of the infrared blinking light from the eye spherical surface is positioned on the optical axis of the microscope, and the reflected light of the blinking light is reflected by the light reception signal from the sensor. It is effective to provide some kind of display means for displaying that the position (coincidence) is on the axis so that a magnified photograph of the observed portion can be taken.

In the above-mentioned eye microscope, a sensor for detecting that the reflected light of infrared blinking light from the eye spherical surface is located on the optical axis of the microscope, and a light receiving signal from the sensor mechanically sets the microscope optical system to a photographing state. It is also possible to provide a switching means for switching regardless of electrical so that a magnified photograph of the observed portion can be taken.

Further, means for generating a displacement signal by detecting a displacement of the light spot from the center of the alignment circle due to infrared blinking light displayed on the television screen,
It is advantageous to provide control means for driving the moving means in the up-down direction and the left-right direction of the microscope optical axis by this deviation signal so as to match the microscope optical axis with the eye axis of the subject.

[0009]

In the eyeball microscope configured as described above, when adjusting the optical axis position (alignment) of the microscope main body with respect to the eyeball of the subject, the eyeball is in the fixation state displayed on the observation screen such as the monitor screen. With respect to the eye axis of the anterior segment image, when the light spot on the screen due to the reflection of infrared light, which is the alignment light irradiated to the spherical surface of the eye through the optical axis of the microscope, is aligned with the eye axis using the alignment circle, it blinks. With the light spots, the light spots can be clearly distinguished from other confusing light spots due to unexpected reflection, etc., and the optical axis of the microscope and the eye axis can be matched easily and accurately without making a mistake. Moreover, since the light spot is blinking, it is easy to perform the matching operation. Therefore, the non-contact type eye microscope main body, in which the optical axis of the illumination system and the optical axis of the observation / photographing system are set in a fixed relation position with respect to the spherical surface of the eye, is accurately adjusted by moving the microscope optical axis forward and backward. It is possible to set a proper focus shooting state.

At the time of aligning the eye axis with the optical axis of the microscope, a sensor for detecting that the reflected light of the blinking infrared light from the spherical surface of the eye is positioned on the optical axis of the microscope is provided, and the light receiving signal from the sensor provides the eye axis. By using a display means such as a lamp or a buzzer that indicates the match between the optical axis of the microscope and the optical axis of the microscope, when the eyepiece and the optical axis of the microscope are matched by operating the microscope mount, it is possible to easily confirm the match. it can.

A sensor for detecting that the reflected light of the blinking infrared light from the eye spherical surface is located on the optical axis of the microscope is provided, and the optical system of the microscope is mechanically operated by the received light signal from the sensor.
By using the switching means for switching to the photographing state regardless of the electrical state, it is possible to make the optical axis of the microscope coincide with the eye axis and at the same time to easily bring the observed portion into the enlarged photographing state.

Then, the deviation of the light spot due to the blinking light from the eye axis of the anterior segment image is detected, and the deviation signal generated by the detection drives the vertical / horizontal moving means of the microscope optical axis to drive the microscope. By controlling the optical axis so that it matches the eye axis of the subject, the microscope pedestal is automatically driven in the vertical and horizontal directions when magnifying observation or taking a magnified picture of the subject, and the optical axis of the microscope is accurate. It is possible to quickly match the eye axis of the subject.

[0013]

Embodiments of the present invention will be described with reference to the accompanying drawings.

FIG. 1 shows an embodiment of the eyeball microscope of the present invention in which the optical system for aligning the microscope optical axis and the optical axis of the corneal endothelial cell photographing optical system are different axes.

In the above embodiment, as the illumination light source of the observed portion, the illumination lamp 3 during observation and alignment of the optical axis of the microscope and the eye axis of the subject, and the enlarged photograph of the corneal endothelial cells are taken. Strobe discharge tube 5 and lighting lamp 3
The light of the illumination lamp 3 is reflected by the mirror 7 so that the focus position of the light emitted by the condenser lens 4 and the focus position of the light emitted by the strobe discharge tube 5 are the same position. The light from the strobe discharge tube 5 is reflected by the mirror 7.
Are arranged so as to pass through the apertures and converge at the position of the diaphragm 8. The light that has passed through the diaphragm 8 passes through the projection lens 9 through the cornea 2 that is the surface to be observed of the subject's eyeball 1 from the oblique direction, by the illumination light from the illumination lamp 3 during observation and optical axis alignment, and by the strobe light during imaging. , Is irradiated at a predetermined angle with respect to the eye axis.

In the optical system for photographing the anterior segment including the iris, the beam splitter 21, the iris photographing lens 22 and the movable portion are sequentially arranged at predetermined positions from the front on the microscope optical axis 22 'which should be located on the eye axis. The movable mirror 23 is provided with a mirror 23.
Is an image of the anterior segment of the eye, and when it is aligned with the optical axis, it turns in parallel with the optical axis, and the iris photographing lens 22 allows the rear television camera.
An image of the anterior segment of the eye is formed on the CCD light receiving surface 25 on the front surface of the CCD 24, and near-infrared blinking light for optical axis alignment described later is projected and imaged.

On the opposite side of the optical axis of the illumination optical system and the optical axis 22 'of the microscope, the cornea of the observed portion receives the reflected light of the oblique illumination light beam from the illumination lamp or strobe with respect to the eye spherical surface. A corneal endothelial cell photographing optical system for magnifying observation or photographing of endothelial cells is provided, and a magnified photographed image is formed on the CCD light receiving surface 25. That is, at a predetermined position on the optical axis 10 ′ that is symmetrical to the optical axis of the illumination optical system while sandwiching the microscope optical axis 22 ′ for anterior segment imaging,
The objective lens 10 on the side of the eye spherical surface, and the mirror 11 at a predetermined distance from the objective lens 10 intersects the optical axis 10 ′ at a predetermined angle, and an image light beam due to the reflected light of the illumination light from the eye spherical surface is converted into the microscope light. The image beam reflected by the mirror 11 is arranged so as to be bent so that it is orthogonal to a predetermined position on the axis 22 ', and the slit 12
And through the image forming lens 13 and is totally reflected by the mirror 23 which is in a state of intersecting with the optical axis 22 'of the microscope at 45 °, and the C of the television camera is displayed.
An enlarged photographed image of corneal endothelial cells on the surface to be observed is formed on the CD light receiving surface 25.

On the other hand, with respect to the beam splitter 21 on the microscope optical axis 22 ', from the side of the direction perpendicular to the optical axis, a fixation target light for presenting the fixation target to the subject, Near-infrared light, which is alignment light for matching the axis with the optical axis of the microscope, is made incident, and these rays are made to travel on the optical axis of the microscope and are made incident on the eye spherical surface. That is, at a predetermined position on the side of the anterior segment imaging optical system having a microscope optical axis, a blinking near-infrared light emitting diode 14 that is alignment light and a blinking visible light emitting diode 15 that is fixation target light. Are arranged so that the optical axis of each ray is parallel to the optical axis 22 'of the microscope.
The blinking near-infrared light from 14 is a condenser lens 16, a mirror 17, a near-infrared light reflecting visible light transmitting mirror 18, a mirror 19, and a condenser lens 20.
It is designed to be reflected by the reflecting surface in the beam splitter 21 to pass through the microscope optical axis 22 'and enter the eye spherical surface, and the blinking visible light from the light emitting diode 15 of blinking visible light is the near infrared light. The light-reflecting visible-light transmitting mirror 18 passes through the mirror 19, the condensing lens 20, and the beam splitter 21 and travels on the microscope optical axis 22 ′ and enters the eye spherical surface, like the above-mentioned near-infrared light.

C, which is the image plane of the television camera 24
The image reception signal of the image formed on the CD light receiving surface 25 is the controller
After being converted to a video signal via 26, the movable mirror 23 is used when observing the anterior segment image and aligning the eye axis with the microscope optical axis 22 '.
And position it almost parallel to the optical axis 22 'of the microscope.
D The image is formed on the light receiving surface 25, and the image of the anterior eye part is displayed on the screen of the monitor 27 which receives the image signal from the control circuit 26 by the signal from the television camera 24. While the dots are displayed at the same time, the movable mirror 23 moves to the optical axis 2 of the microscope when magnifying the corneal endothelial cells of the subject.
An enlarged image of the corneal endothelial cells of the observed part is displayed on the monitor 27 which receives the video signal from the controller 26 by forming a magnified image light beam on the light receiving surface 25 of the television camera in a 45 ° crossing state with 2 '. (b) It is done.

When the anterior segment image is displayed on the monitor screen together with the light spot by the blinking near-infrared light which is the alignment light, the controller is installed in the pupil part of the eyeball image in which the fixation target light is fixed. The alignment circle 28 of a predetermined diameter is formed by the electric signal from 26, and the alignment of the microscope optical axis and the eye axis, that is, the alignment operation, is performed by the alignment light at the center of the alignment circle 28 on the monitor 27 screen. This can be done by moving the microscope body vertically and horizontally so that a certain blinking light spot 29 comes to the position 27 (a). This makes it possible to easily match the optical axis of the microscope and the eye axis of the subject, rather than by groping, and when the imaging state is set, a magnified image of the corneal endothelial cells of the observed part is displayed by the illuminated illumination lamp. It can be observed, and a magnified photograph can be taken by a known means with the strobe discharge tube turned on. Then, when aligning the eye axis and the optical axis of the microscope, in the present microscope, the light spot which is the index of the alignment light on the monitor screen is easily blinked because it is not misunderstood with other confusing light spots. The position can be adjusted. In the present embodiment, the fixation target light is blinking light, but this is intended to suppress the slight movement of the eyeball by fixing the blinking object, and it is of course possible to use light that does not blink. is there.

FIG. 2 shows an embodiment in which the optical system for aligning the microscope optical axis and the optical axis of the corneal endothelial cell photographing optical system are coaxial with each other in the eyeball microscope of the present invention.

The above-mentioned optical system serves as an illumination light source for the portion to be observed, and an enlarged photograph is taken of the illumination lamp 3 at the time of observation and alignment of the optical axis of the microscope, and the focusing position of the light emitted from the lamp 3 by the condenser lens 4. The stroboscopic discharge tube 5 is arranged at the time. The light from the lamp 3 is condensed by the condenser lens 4 and the light from the stroboscopic discharge tube 5 is converged by the condenser lens 6, and a fixed slit 12 with a predetermined gap is provided at the converging position of the lens 6.
The slit 12a has a slit projection lens 31 and an objective lens which will be described later.
It is placed in the vicinity of the common focal point of the spherical surface of the eye (cornea) 2 which is the surface to be observed by 34. The illumination light beam that has passed through the slit 12a is reflected by a mirror 30 and then passes through a slit projection lens 31 and is reflected by a mirror 32 disposed on one side of the microscope optical axis and travels substantially parallel to the microscope optical axis 34 '. After passing through the lower half of the transparent mirror 33, the light enters the objective lens 34 and illuminates the ocular spherical surface 2 in a direction perpendicular to the plane of the paper.

When the objective lens 34 is at a predetermined distance from the eye spherical surface 2 of the subject in a non-contact state from the eye spherical surface, the image rays obtained by the objective lens 34 cause the television cameras 24 ₁ and 24 _{2 to be} described later. An image of the anterior segment of the eye including the iris is formed on the CCD light receiving surfaces 25 ₁ and 25 ₂ of the image forming device, and an enlarged image of corneal endothelial cells of the subject is formed on the latter. That is, the objective lens 34
The image light beam obtained by the
The light is focused and reflected at the intersection with the front surface, travels on the optical axis 39 'perpendicular to the optical axis 34', passes through the semi-transparent mirror 38, and is imaged by the imaging lens 39 to the CCD of the television camera 24 ₁ for optical axis alignment. While the anterior segment image is formed on the light receiving surface 25 ₁ , the semitransparent mirror 33
An imaging lens 35 forms a magnified image of the corneal endothelial cells of the test area on the CCD light receiving surface 25 ₂ of the TV camera 24 ₂ for corneal endothelial cell magnifying imaging.

On the other hand, with respect to the semitransparent mirror 33 on the optical axis 34 'of the microscope, a fixation target for presenting the fixation target to the subject from the side perpendicular to the optical axis 34'. Light and near-infrared light that is alignment light for matching the eye axis and the microscope optical axis are made incident, and these rays are made to travel on the microscope optical axis 34 ′ and be made incident on the eye spherical surface 2. It is like this. That is, at a predetermined position lateral to the microscope optical axis 34 ', which is the optical axis of the corneal endothelial cell imaging optical system, the blinking near-infrared light emitting diode 14 that is the alignment light and the visible light that is the fixation target light are emitted. The diode 15 is arranged so that the former emission optical axis is parallel to the microscope optical axis 34 'and the latter emission optical axis is orthogonal to this, and the blinking near infrared light from the blinking near infrared light emitting diode 14 is It passes through the transparent mirror 17 ', the condenser lens 20', and is reflected by the semitransparent mirror 38, so that the semitransparent mirror 33 on the microscope optical axis 34 'is reflected.
When the microscope optical axis 34 'and the eye axis coincide with each other, the near infrared light which is the alignment light is reflected by the objective lens 34 and is incident on the eye spherical surface 2 on the microscope optical axis 34'. Is reflected by the eye spherical surface 2 and goes backward on the optical axis 34 ', and the objective lens
It is reflected by the semi-transparent mirror 33 through 34, travels on the optical axis 39 'perpendicular to the microscope optical axis 34', passes through the semi-transparent mirror 38 and the imaging lens 39, and the optical axis alignment TV camera 24 ₁ The near-infrared light of the alignment light is formed on the light receiving surface 25 _{1 of the} eye as a blinking light spot together with the anterior segment image including the iris.

Then, the television camera for position adjustment 24 ₁
The image signal formed by the anterior segment image including the iris and the blinking light spot of the alignment light formed on the CCD light receiving surface 25 ₁ which is the image forming surface of the image signal is converted into the image signal through the controller 36 and the image signal is received. An anterior segment image and a blinking spot of near-infrared light from the eye spherical surface are simultaneously displayed on the screen of the monitor 27A, and an electric signal from the controller 36 is used to fix the fixation target eye to the eye image. An alignment circle 28 of a predetermined diameter is formed in the pupil part of the, and when the blinking light point 29, which is the alignment light, is moved to the center of the alignment circle 28 by moving the microscope body vertically and horizontally, the sensor The controller 36 operates in response to the detection signal from the CCD light receiving surface, and the buzzer 37 for notifying the alignment of the microscope optical axis 34 'and the eye axis operates to notify that the alignment of the microscope optical axis is completed. ing.

On the other hand, the television camera 24 on the microscope optical axis 34 '
₂ is a signal of the optical axis alignment completion from the controller 36, which allows the microscope main body to be moved in the front-rear direction to observe a focused magnified image, and the optical axis alignment completion signal and the electrical signal at the time of focusing. The stroboscopic discharge tube 5 is automatically caused to emit light, and an enlarged image of the corneal leather cells in the test area is displayed on the screen of the monitor 27B. Then, the magnified image can be photographed on the film surface by a photographing means (not shown). In the above case, instead of the buzzer 37, the optical axis alignment display lamp may be turned on to indicate the completion of the optical axis alignment. In this way, the blinking light spot on the alignment monitor 27A makes it possible to easily and accurately align the microscope optical axis without mistaking it for other confusing light spots. In this case, the completion of alignment is displayed on the monitor screen. Even without paying attention, it is possible to easily know, and further, by focusing, it is possible to easily perform magnified observation and photographing of the corneal endothelial cells on the surface to be observed.

FIG. 3 is a block diagram of an optical axis automatic alignment device for an eye microscope in which the optical axis of the microscope and the eye axis of the subject are automatically aligned. By using the present apparatus for the eyeball microscope of the embodiment of FIG. 1, for example, an eyeball microscope capable of automatically magnifying the optical axis of the microscope with the eye axis of the subject and capable of magnifying an image of the subject is obtained. You can

In the optical system for photographing the anterior segment of the eye including the iris of the subject and aligning the optical axis of the microscope, the beam is sequentially moved to a predetermined position from the front on the optical axis 22 'which should be located on the eye axis. The splitter 21, the iris photographing lens 22, and the light-receiving surface 25 of the television camera 24 are provided, and when the microscope optical axis 22 'and the eye axis are aligned, the image light beam of the anterior segment irradiated by the illumination means (not shown) is The iris photographing lens 22 forms an image on the CCD light receiving surface 25 in front of the television camera 24.

In order to match the fixation target light for presenting the fixation target to the subject from the side of the microscope optical axis 22 'and the eye axis of the subject and the microscope optical axis 22'. In order to make near-infrared light, which is the alignment light of, enter the eye spherical surface 2 through the microscope optical axis 22 ', at a predetermined position on the side of the microscope optical axis,
A blinking near-infrared light emitting diode 14 and a blinking visible light emitting diode 15 as a fixation target for suppressing eye movements in the fixation state, the optical axis of each emitted light beam is the microscope optical axis 2
2'is arranged so as to be parallel to the blinking near-infrared light from the blinking near-infrared light emitting diode 14, and the condensing lens 16, mirror 17, near-infrared light reflecting visible light transmitting mirror 18, mirror 19 The light is reflected by the reflection surface in the beam splitter 21 through the condenser lens 20 and is incident on the eye spherical surface 2 on the microscope optical axis 22 '. Is a near-infrared light reflection visible light transmission mirror
After passing through 18, through the mirror 19, the condenser lens 20, and the beam splitter 21, the near-infrared light passes through the microscope optical axis 22 ′ and enters the eye spherical surface 2. As a result, when the microscope optical axis 22 'and the eye axis coincide with each other, the near-infrared light that is the alignment light is reflected by the eye spherical surface 2 and the optical axis 22' is reflected.
It goes backward and passes through the beam splitter 21 and the iris photographing lens 22 and forms an image with the anterior segment image as a blinking light spot on the light receiving surface 25 of the television camera 24 for optical axis alignment.

The image signal from the television camera, which is formed by the anterior segment image including the iris imaged on the light receiving surface 25 of the television camera 24 and the blinking light spot of the alignment light, is converted into a video signal via the controller 40, The controller that receives the alignment circle signal from the pattern generator 42 while the anterior segment image and the blinking light spot by the near infrared light reflected by the eye spherical surface 2 are simultaneously displayed on the screen of the monitor 27C that receives the image signal. The circle video signal from 40 forms an alignment circle 28 having a predetermined diameter on the eyeball image in which the fixation target light is fixed. Further, the flicker detection device 41 receiving the electric signal from the controller 40 detects the position of the flicker, that is, the blinking light point of near infrared light. This position detection signal is re-input to the controller 40, converted into displacement signals in the X, Y directions that are up, down, left and right from the microscope optical axis 22 ', and input to the motor drive circuit 43. Then, a motor for driving the gantry of the eye microscope in the XY directions (vertical and horizontal directions) by the control signal from the motor drive circuit 43.
44 is operated to eliminate the deviation of the optical axis of the microscope from the vertical and horizontal directions of the eye axis so that the optical axis coincides with the eye axis, and this state can be confirmed on the monitor 27C. There is. In the figure, the blinking light spot 29 is located at the center of the alignment circle 28 in the iris of the monitor screen, and represents the state where the optical axis of the microscope and the eye axis coincide with each other on the same axis.

When the microscope optical axis and the eye axis of the alignment optical system are aligned using the above-mentioned device, the fixation target light is presented to the subject and the blinking near-infrared light as the alignment light is presented. It illuminates the spherical surface of the eye 2 and the light receiving surface 25 of the TV camera 24
It is possible to automatically match the optical axis of the eyeball image formed above with the light spot of the alignment light to perform the above-mentioned alignment and confirm this, and use it in combination with the corneal endothelial cell imaging optical system for the eye microscope. This can contribute to automation of magnified imaging of corneal endothelial cells. Further, when detecting that the light spot 29 of the alignment light is located at the center of the alignment circle 28 by the flitter detection device 41, since the light spot is a blinking light spot, it suffices to electrically detect what blinks. However, unlike the case where a simple non-blinking light spot is detected from other confusing screen portions, the position of the optical axis can be detected and aligned very easily at any position on the screen.

[0032]

According to the ocular microscope of the present invention as set forth in claim 1, the corneal endothelial cells in the observed part of the eyeball of the subject are magnified and photographed. On the other hand, when adjusting the optical axis position of the microscope body, taking advantage of the blinking light spot which is the alignment light displayed with the anterior segment image on the observation surface of the anterior segment image display means such as the monitor screen,
The position of the microscope optical axis and the eye axis can be easily aligned without making a mistake by clearly distinguishing from other light spots due to unexpected reflection and the like. Moreover, since the above-mentioned light spots are blinking, there is an advantage that it is easy for an observer to recognize and the operation of alignment is easy.

According to the second aspect of the present invention, when the eye axis and the optical axis of the microscope are aligned with the eye spherical surface of the subject, the display means such as a buzzer or a lamp is operated during the alignment operation. The inspector is informed that the alignment between the optical axis and the optical axis of the microscope has been completed, so that the alignment can be easily confirmed.

According to the third aspect of the invention, when the magnified photograph of the corneal endothelial cells of the observed portion of the eyeball is taken, when the eye axis and the optical axis of the microscope are aligned and aligned,
Upon the completion of the alignment of the optical axes, the switching means can be operated to bring the corneal endothelial cells in the observed region to the enlarged photographed state.

According to the fourth aspect of the invention, when the corneal endothelial cells of the eyeball of the subject are magnified and photographed, the deviation between the optical axis of the microscope and the eye axis of the subject is automatically detected. It is possible to provide an eyeball microscope capable of detecting and eliminating this and aligning the optical axis of the microscope, which can contribute to automation of the above-described magnified photography. In addition, when the vertical and horizontal deviations of the optical axis of the microscope are detected and the optical axes are aligned, the blinking light spot is used, so that the light spot is electrically identified by distinguishing it from other confusing light spots. It is possible to easily grasp the position and easily align the optical axis.

[Brief description of drawings]

FIG. 1 is a configuration diagram showing an embodiment of an eye microscope according to the present invention,

FIG. 2 is a configuration diagram showing another embodiment of the eye microscope according to the present invention,

FIG. 3 is a block diagram of an optical axis automatic alignment device for an eye microscope.

[Explanation of symbols]

1 ... Eyeball, 2 ... Eye spherical surface (cornea), 3 ... Illumination lamp,
5 ... Strobe discharge tube, 9 ... Illumination light projection lens, 10 ...
Objective lens, 13 ... Imaging lens, 14 ... Blinking near infrared light emitting diode, 15 ... Visible light emitting diode, 22 ... Iris projection lens, 22 '... Microscope optical axis, 24, 24 ₁ , 24 ₂ ... TV camera, 25, 25 ₁ , 25 ₂ … CCD light receiving surface, 26… Controller, 27, 27A, 27B, 27C… Monitor, 28…
Alignment circle, 29 ... Blinking light spot, 34 ... Objective lens, 34 '... Microscope optical axis, 35 ... Imaging lens, 36 ... Controller, 37 ... Buzzer, 40 ... Controller, 41 ...
Flicker detector, 44 ... X / Y direction gantry drive motor.

Claims (4)

[Claims] 1. An eyeball microscope configured to perform magnifying observation or photographing of a corneal endothelial cell in an observed portion of an eyeball of a subject, and to inspect a predetermined infrared blinking light through at least a microscope optical axis. A means for irradiating a fixation target light as well as a means for irradiating the eye spherical surface of a person, an anterior eye image display means for displaying an anterior eye image on an observation surface, and an alignment circle display means for displaying an alignment circle on the anterior eye image And, characterized in that the alignment of the microscope optical axis to the eye spherical surface by the coincidence of the light spot by the reflected light of the blinking light from the eye spherical surface of the subject on the observation surface and the alignment circle, Eye microscope to do. 2. A magnifying device for observing an area to be observed, comprising a sensor for detecting that the reflected light of the blinking light from the ocular spherical surface is positioned on the optical axis of the microscope, and a display means for displaying the received light signal from the sensor. The eye microscope according to claim 1, wherein the eye microscope is capable of taking a photograph. 3. A sensor for detecting that the reflected light of the blinking light from the ocular surface of the eye is positioned on the optical axis of the microscope, and a switching means for switching the microscope optical system to a photographing state by a light reception signal from the sensor. The eye microscope according to claim 1, wherein an enlarged photograph of the observed portion can be taken. 4. A microscope for detecting a deviation of a light spot from the center of an alignment circle due to the blinking light to generate a deviation signal, and driving the up-down and left-right moving means of a microscope optical axis by the deviation signal. The control means for aligning the optical axis with the eye axis of the subject is provided.
The described ocular microscope.