JPH0585880U - Hollow fiber sheet - Google Patents

Abstract

(57) [Summary] [Object] To provide a hollow fiber sheet in which a hollow fiber is reliably woven and knitted without damaging or crushing the hollow fiber with a warp when the hollow fiber is woven or knitted. [Structure] At least one hollow fiber is used as a weft, and the hollow fiber is woven and knitted in the shape of a warp. The hollow fiber is woven and knitted. By controlling the strength of the warp, the hollow fiber is damaged. The sheet can be woven and knitted without fail.

Description

[Detailed description of the device]

[0001]

[Industrial applications]

 TECHNICAL FIELD The present invention relates to a hollow fiber sheet in which at least one hollow fiber is used as a weft thread and is woven and knitted in a warp-like manner, and more particularly to a hollow fiber sheet used in a fluid treatment device using the hollow fiber.

[0002]

[Prior Art]

 Conventionally, hollow fibers such as regenerated cellulose, polypropylene and polysulfone have been widely used in the industrial field, medical field and the like. The hollow fibers are assembled into various shapes suitable for the purpose of use, housed in a housing, and used as a module. In recent years, as a hollow fiber to be accommodated in a housing, a module has been proposed in which the hollow fiber is used as a weft yarn, and sheet-like hollow fibers woven and knitted in the shape of a warp are laminated or wound to be accommodated in the housing. (For example, Japanese Patent Laid-Open No. 2-99067).

[0003]

[Problems to be solved by the device]

 If a sheet-shaped hollow fiber woven in the shape of a blind is used as the hollow fiber housed in the housing, the distribution of the hollow fibers in the housing will be uniform, and uneven distribution of the fluid flowing outside the hollow fibers can be prevented. The processing efficiency per unit membrane area can be improved, but when the warp knitting force is too strong when weaving the hollow yarns into the warp yarns, leakage may occur at the knitting (weave) portion, or Even if the module passed the leak test, the part in contact with the warp was scratched by friction or flattened by being crushed by the warp. As a result, cracks may occur, and the fluid to be treated leaks into or out of the hollow fibers from the cracked portions.

Particularly in the medical field, leakage of treated blood is a great damage to the patient and must be absolutely avoided. Therefore, an object of the present invention is to provide a hollow fiber sheet in which the hollow fibers are reliably woven and knitted without warping or crushing the hollow fibers by warp when the hollow fibers are woven or knitted.

[0005]

[Means for Solving the Problems]

 The present inventors have found that the damage or crushing of the hollow fibers by the warp threads is due to the strength of the warp knitting when weaving the hollow fibers, that is, the force to form a mesh, and further investigated. The invention has been reached.

That is, according to the present invention, at least one hollow fiber is used as a weft yarn, and in a hollow fiber sheet woven in a warp-like weave pattern, hollow fibers arranged at a density of n / cm are used. The strength of the warp knitting of the warp threads when weaving with a cm warp thread is 100 g and the force for pulling out one hollow fiber in the center from a hollow fiber sheet containing 21 hollow fibers is 100 g. It is a hollow fiber sheet characterized in that it is configured to have a weight of not more than that. However, 100 ≧ n ≧ 3, 2 ≧ p ≧ 0.2.

In order to pull out one central hollow fiber from the hollow fiber sheet, it is necessary to arrange at least 10 hollow fibers on both sides of the hollow fiber to be pulled out. If less than 10 hollow fibers are arranged, the measured values will fluctuate and accurate drawing force cannot be measured. In the case of a hollow fiber sheet having a narrow width and the number of warp yarns is less than 100, the pull-out force proportional to the number of warp yarns may be considered and converted to the case where the number of warp yarns is 100.

The strength of the warp knitting, that is, the degree of tightness of eyes, is 100 g or less, usually 5 g or less, when the force required to pull out one hollow fiber from a hollow fiber sheet consisting of 100 warps is used as an index. Heavy to 40 g weight is preferred. If the weight exceeds 100 g, the hollow fiber may be damaged by friction with the warp thread, or the hollow fiber may be crushed and flattened to impair the membrane performance, and may be damaged or the flattened portion may be cracked. A smaller force for pulling out the hollow fiber from the sheet is preferable because it does not damage the hollow fiber, but if it is too small, the hollow fiber cannot be woven or knitted to maintain the sheet shape. If the force for pulling out the hollow fibers is 5 g or more, the shape of the sheet can be sufficiently retained. Usually, in order to maintain the shape of the hollow fiber, a pulling force of 10 g or more is preferably adopted.

[0009]

[Action]

 The hollow fiber sheet of the present invention suppresses the knitting strength of the warp yarns to a certain value or less, thereby damaging the hollow fibers due to friction with the warp yarns, and crushing the hollow fibers by the warp yarns, and thus the hollow fiber by crushing Can be prevented from cracking. The hollow fiber sheet of the present invention can be safely used clinically because it can completely prevent blood leakage when applied to a module for medical use.

[0010]

【Example】

 Next, an embodiment of the present invention will be described with reference to the drawings. FIG. 1 is a perspective view of a hollow fiber sheet knitted in the shape of a blind, and the hollow fiber 1 is knitted in the shape of a blind with a warp 2 using one or a plurality of bundles as a unit weft. When a bundle of a plurality of hollow fibers is knitted in a blind shape, a bundle of 37 or less, preferably 19 or less hollow fibers is used. In the case of a bundle of 37 or more hollow fibers, it is not preferable because one hollow fiber in one bundle cannot come into sufficient contact with the fluid, and the mass exchange efficiency may decrease. Usually, one hollow fiber is used as a weft yarn to woven and knit a blind-shaped hollow fiber sheet as shown in FIG. In this case, not only 100% of the surface area of each hollow fiber is utilized for substance exchange with the fluid, but also the uniform slits formed by the weft threads, which are small in the square shape, divide the fluid into minute units. Perhaps because of the extremely efficient mixing, unexpectedly high mass exchange performance can be achieved with a small membrane area, and pressure loss is also small.

The material of the hollow fiber is not particularly limited, but a material having an outer diameter of 50 to 100 μm and a thickness of 3 to 500 μm is used. Usually, those having an outer diameter of 100 to 500 μm and an inner diameter of 6 to 100 μm are preferably used. The density of the hollow fibers forming the sheet, n fibers / cm, is preferably changed according to the outer diameter of the hollow fibers. When used for medical purposes, the larger the outer diameter of the hollow fiber, the smaller the density n, and generally 100 ≧ n ≧ 3. When n exceeds 100, the pressure loss becomes too large and hemolysis and the like tend to occur. When n is less than 3, the effect of stirring the fluid by the hollow fibers cannot be obtained and the effect of weaving cannot be obtained. On the other hand, when p exceeds 2, the coverage of the surface of the hollow fiber by the knitting yarn becomes too high and the effect is lowered. On the other hand, if p is less than 0.2, the hollow fibers will not be sufficiently fixed, and the effect of weaving will not be obtained.

[0012] The warp yarns that are woven and knitted in the shape of a blind are preferably solid solid yarns, such as polyester, polyamide, polyimide, polyacrylonitrile, polyethylene, polypropylene, polyarylate, and polyvinyl alcohol, which are thin and strong. Used. Among them, polyester and polyamide yarns have suitable softness and mechanical strength, and are therefore preferred because they do not damage the hollow fibers when they are processed into a blind shape.

Any knitting method may be used to weave and knit the hollow fibers in the shape of a blind with the warp yarns 2. However, as shown in FIG. 2, the warp yarns usually form a stitch around the hollow fibers 1. A method (for example, chain knitting) in which each hollow fiber is formed and fixed one by one with warp threads is preferably adopted. In such a woven or knitting method, there is no displacement of the hollow fibers during use, and the gap between the adjacent hollow fibers can always be kept constant and the processing efficiency can be improved.

When the hollow fiber sheet of the present invention is used in the medical field, the use of an oil agent in the solid yarn used in the warp should be avoided as much as possible, but when it is unavoidable to use it in the form of a blind. For this, it is necessary to use one that has been confirmed to be safe, or an oil that can be removed by washing.

Experimental Example 1 As hollow fibers, one hollow fiber made of poly-4methylpentene-1 having an inner diameter of 210 μm and an outer diameter of 260 μm and a length of 100 cm is arranged so that the density in the length direction is 22 fibers / cm. Then, 100 hollow polyester denier fibers of 12 denier and 12 filaments were used as warp yarns, and the above hollow fibers were woven and knitted in a blind shape at a density of 0.9 filaments / cm. Five types of hollow fiber sheets having a length of 5 cm were prepared so that the pulling-out force of the yarn was 35 g weight, 60 g weight, 80 g weight, 110 g weight, and 160 g weight, respectively. Next, Table 1 shows the results of investigating the leak rate of 12 hollow fibers forming this hollow fiber sheet. From the results in Table 1, it can be seen that the leak rate of the hollow fiber sheet having a drawing force per hollow fiber of 100 g or less is low.

Experimental Example 2 Polypropylene porous hollow fibers each having an inner diameter of 280 μm, an outer diameter of 380 μm, and a length of 100 cm were arranged as hollow fibers so that the density in the length direction was 16 fibers / cm, and 150 warps were used. Denier, 24 filament polyester solid yarn with a density of 0. The above-mentioned hollow fibers were woven and knitted in the shape of a blind at 25 fibers / cm, and 5 kinds of hollow fiber sheets were prepared in the same manner as in Experimental Example 1, and the results of investigation of the leak rate as in Experimental Example 1 are shown in Table 1. .. Also in Experimental Example 2, as in Experimental Example 1, it is clear that the leak rate of the hollow fiber sheet having 100 g weight or less per hollow fiber is low.

[0017]

[Table 1]

Experimental Example 3 The hollow fiber sheets used in the experimental example and having a pulling force of 35 g are laminated so that the number of laminated layers per unit thickness is 36 sheets / cm and the width is 4 cm. A laminate of hollow fiber sheets was formed. The laminated body is housed in a rectangular tubular housing 5 shown in FIG. 3, resin 6 is filled on both sides of the laminated body and the side walls of the housing, and both ends of the hollow fiber 1 are covered with polyurethane resin partition walls 7. A liquid-tight contact was made to prepare an artificial lung. The effective length of the hollow fiber was 4 cm, and the effective membrane area was 0.31 m ↑ 2.

Next, a blood circuit was connected to the blood inlet 10 and the outlet 11 of the artificial lung to form a closed circuit. A gas supply circuit was connected to the gas inlet 12. 13 is a gas outlet. Bovine blood heated to 37 ° C. was circulated in the above blood circuit at 2000 ml / min for 6 hours, but no hollow fiber leaked.

[0020]

EFFECTS OF THE INVENTION As described above, the hollow fiber sheet of the present invention does not cause damage to the hollow fiber due to contact with the warp threads or flattening, and therefore there is no fluid leakage and efficient treatment can be performed. Especially when used for medical purposes, there is no blood leakage, so it has the effect of being able to be used safely for a long time in clinical practice.

[Brief description of drawings]

FIG. 1 is a perspective view of a blind-shaped hollow fiber sheet.

FIG. 2 is a cross-sectional view showing a state in which hollow fibers are woven and knitted in a blind shape.

FIG. 3 is a perspective view of an artificial lung using a hollow fiber sheet.

[Explanation of symbols]

 1 hollow fiber 2 warp

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor, Katsu Nodo, Kuraray Co., Ltd. 1621 Sakata, Kurashiki City, Okayama Prefecture

Claims (1)

[Scope of utility model registration request] 1. A hollow fiber sheet in which at least one hollow fiber is used as a weft and is woven and knitted in the form of a warp, and hollow fibers arranged at a density of n / cm are used as p warps. The strength of the warp knitting when weaving with 100 warp threads and 2
A hollow fiber sheet comprising a hollow fiber sheet containing one hollow fiber, and a force for pulling out one hollow fiber in the center is 100 g or less. However, 100 ≧ n ≧
3, 2 ≧ p ≧ 0.2.