JPH0584337U - In vitro blood circulation circuit - Google Patents

Abstract

(57) [Summary] (Modified) [Constitution] In a circulation circuit for concentrating blood and returning blood to the living body again, an outlet 1a of a reservoir 1 and an inlet 2a of a blood concentrator 2 are provided with a concentration pump 3 interposed. Then, the first tube 7 is used for connection, and a branch portion 7a is provided between the concentrating pump 3 of the tube 7 and the inflow port 2a of the blood concentrator 2 to be branched and connected to the inflow port pressure measuring unit 4. The outlet 2a of the blood concentrator 2 and the inlet 5a of the chamber 5 are connected by a second tube 8, and a recirculation outlet 5b and a living body side outlet 5c are formed in the chamber 5, and a living body side outlet is formed. 5c and living body M are blood return pumps 6
And is connected by the third tube 9. Recirculation outlet 5
b was directly connected to the upper part of the reservoir 1, and an atmosphere opening port 1d was formed above the reservoir 1 to maintain the atmosphere open state even during circulation of blood. [Effect] Concentrated hematocrit that returns blood can be easily estimated based on the measurement value measured by the inflow port measurement unit arranged near the inflow port of the blood concentrator. Therefore, it is widely used for blood collection such as surgery.

Description

[Detailed description of the device]

[0001]

[Industrial applications]

 The present invention collects blood remaining in an artificial cardiopulmonary circuit after bloodless extracorporeal circulation or blood bleeding during a surgical operation in a reservoir to separate impurities in the blood and concentrate the blood. It relates to a circulation circuit that returns blood to the living body again.

[0002]

[Prior art and its problems]

 Recent advances in medical technology are remarkable, and more or less everyone is living to benefit from it.Various types of in vitro blood circulation circuits have been developed, and by measuring the inlet pressure of the blood concentrator. Since the hematocrit on the outlet side of the liquid concentrator is approximately proportional (see Fig. 2), it is possible to measure the inlet pressure of the liquid concentrator to return blood to the living body. Moreover, a circuit that can be easily measured has not yet been developed.

For example, in the conventional example shown in FIG. 3, an outlet 1 a that connects the inlet 2 a of the blood concentrator 2 to the lower end of a reservoir 1 having a blood recovery port 1 b by a tube C 1, and a living body M An outlet 1x connecting the blood return tube C2 is formed, and the blood concentrated by the blood concentrator 2 is returned to the reservoir 1 and repeated for a plurality of times, and the inlet pressure measurement unit 4 near the blood concentrator 2 is formed. The hematocrit is measured by measuring the hematocrit and driving the blood-returning pump 6 with a variable flow rate to return the blood. Although the hematocrit can be measured almost accurately, the blood is returned to the reservoir 1 and sent to the living body M. Since the blood is sent, even if the hematocrit is estimated from the measured value at the inlet pressure measuring unit 4, the blood to be returned is not always the hematocrit described above, and there is a problem.

Further, in another conventional example shown in FIG. 4, an outlet 2b of the blood concentrator 2 and an inlet 1y of the reservoir 1 are connected by a tube C3, and a branch portion C is provided in the tube C3. The blood immediately after being concentrated in the living body M is returned from the branch portion C, but when the blood return pump 6 is driven to return blood, the flow rate thereof causes the flow from the inlet 2a of the blood concentrator 2 to the flow of the reservoir 1. This causes a problem that the pressure up to the inlet 1y fluctuates and the pressure measurement value of the inlet pressure measurement unit 4 does not match the hematocrit.

[0005]

[The purpose of the device]

 In view of the above-mentioned problems, the present invention has made it possible, as a result of the study, to measure the pressure measured by the inlet pressure measuring portion near the inlet of the blood concentrator without being affected by the blood flow rate by the variable flow rate return pump to the living body. Changes only due to changes in hematocrit, and it is possible to grasp the blood hematocrit at the outlet of the hemoconcentrator by the measurement value of the inlet pressure measurement part, and provide an in vitro blood circulation circuit that can return the blood of a predetermined hematocrit. It is intended for that purpose.

[0006]

[Device configuration]

 The configuration of the present invention comprises a reservoir, a blood concentrator, a concentrating pump, an inlet pressure measurement unit, a chamber, and a blood return pump, and concentrates the reservoir outlet and the blood concentrator inlet. The first tube is connected via a pump, and a branch is provided between the concentrating pump of the first tube and the inflow port of the blood concentrator to make a branch connection with the inflow port pressure measurement unit. The outlet and the inlet of the chamber are connected by a second tube, the chamber forms a recirculation outlet and a living body side outlet, and the living body side outlet and the living body are provided with a blood return pump to form a third It is connected by a tube, the recirculation outlet is directly connected to the upper part of the reservoir, and the atmosphere opening port is formed above the reservoir.

[0006]

[Example of device]

 Hereinafter, the present invention will be described in detail with reference to the drawings of an in vitro blood circulation circuit according to an embodiment.

FIG. 1 is an overall circuit diagram showing an embodiment of an in vitro blood circulation circuit according to the present invention, and FIG. 2 shows a pressure measurement value at an inlet pressure measuring unit and a hematocrit at an outlet of a liquid concentrator. FIG. 3 is a diagram showing an example of the relationship of FIG. 3, FIG. 3 is a conventional example, and FIG. 4 is another conventional example.

The present invention collects blood remaining in an artificial cardiopulmonary circuit after operation such as bloodless extracorporeal circulation or blood bleeding during a surgical operation in a reservoir 1 to separate impurities in the blood, The present invention relates to a circulation circuit for concentrating blood and returning the blood to the living body M again. In an in vitro blood circulation circuit equipped with an inlet pressure measuring unit 4, a chamber 5, and a blood return pump 6 for the living body M, the outlet 1a of the reservoir 1 and the inlet 2a of the blood concentrator 2 are concentrated. The first tube 7 is connected via the pump 3, and a branch portion 7a is provided between the concentration pump 3 of the first tube 7 and the inflow port 2a of the blood concentrator 2 to connect to the inflow port pressure measuring unit 4. It is branched and connected to the outlet 2b of the hemoconcentrator 2 and the chat. The inlet 5a of the valve 5 is connected by the second tube 8 to form a recirculation outlet 5b and a living body side outlet 5c to the chamber 5, and the living body side outlet 5c and the living body M are separated from each other. A variable flow rate blood return pump 6 was interposed and connected by a third tube 9 to directly connect the recirculation circulation outlet 5b and the upper part of the reservoir 1, and an atmosphere opening port 1d was formed above the reservoir 1. This keeps the atmosphere open even during circulation of blood.

That is, the in vitro blood circulation circuit of the present invention includes a reservoir 1, a blood concentrator 2, a concentration pump 3, an inlet pressure measurement unit 4, a chamber 5, a blood return pump 6, and a blood return pump 6, respectively. It comprises a first tube 7, a second tube 8 and a third tube 9 to be connected.

First, blood to be concentrated is injected into a recovery port 1b formed above the reservoir 1 and opened by a suction pump (not shown) such as a roller pump, and the reservoir 1 is provided with a filter 1c. The coarse impurities contained in the interior and solid in advance are filtered, and the filtered blood flows out from the outlet 1a formed at the lower end of the reservoir 1. The flow of the outlet 1a and the blood concentrator 2 is The inlet 2a is connected by a first tube 7 via a concentrating pump 3 such as a roller pump driven at a constant flow rate.

Further, a branching part 7a branched in three is previously provided between the concentration pump 3 of the first tube 7 and the inflow port 2a of the blood concentrator 2, and the branching part 7a is divided into parts. The tip of the branched tube is connected to the inlet pressure measuring unit 4, and the inlet pressure measuring unit 4 measures the pressure value detected by the pressure sensor 4a.

Next, the blood concentrator 2 is an ultrafine fibrous hollow tube made of polypropylene or the like packed in a cylindrical body in a bundle shape. Blood flows in the hollow tube and impurities pass through the tube wall. The blood outlet 2a of the blood concentrator 2 is connected to the inlet 5a of the chamber 5 by the second tube 8.

The chamber 5 has an inflow port 5a connected to one end of the second tube 8 at the upper side, a recirculation outflow port 5b at the lateral side, and a living body side outflow port at the lower side of the chamber 5. 5c is formed, and the living body side outlet 5c is also connected to the third tube 9 connected to the vein of the living body M via a catheter or the like, and the blood is returned to the third tube 9 when returning blood. A blood flow return pump 6 having a variable flow rate to be driven is installed.

The upper part of the chamber 5 and the upper part of the reservoir 1 are directly connected to each other by the recirculation outlet 5b, so that the atmosphere is opened by the atmosphere opening 1d formed in the reservoir 1 even during circulation of blood. It is in communication with the atmosphere of.

That is, the recovered blood is injected from the recovery port 1b, filtered by the filter 1c of the reservoir 1, flows into the first tube 7 from the outlet 1a, and is sent to the blood concentrator 2 by the concentrating pump 3 having a constant flow rate. The blood that has been collected and concentrated in the blood concentrator 2 is sent from the outlet 2b of the hemoconcentrator 2 to the inside of the chamber 5 through the inlet 5a of the chamber 5 through the second tube 8 and the upper portion of the chamber 5 is recirculated. It is in communication with the atmosphere through the outlet 5b, and flows into the chamber 5 in the form of a drip from the inlet 5a of the chamber 5, and the blood return pump 6 is driven in a state where the target hematocrit is not concentrated. However, blood is overflowed from the recirculation outlet 5b of the chamber 5 and returned to the reservoir 1 and is concentrated by circulating it a plurality of times. Then, for example, hematocrit is estimated along the display of the pressure value in the inlet pressure measurement unit 4 along with the data shown in FIG. 2 which is measured and set in advance, and the blood return pump 6 is driven to drive the living body M. To return blood to.

2 shows the pressure value (mmHg) measured in the vertical direction by the pressure sensor 4a of the inlet pressure measuring unit 4 of the inlet 2a of the blood concentrator 2, and the horizontal direction thereof. 2 shows the hematocrit (Ht%) of the blood at the outlet 2b of the second, for example, when the measured value of the inlet pressure measuring unit 4 is 180 mmHg, the hematocrit at the outlet 2b is about 45%. Therefore, this figure is an example and may vary depending on the measurement conditions.

According to the present invention, by providing the recirculation outlet 5b which communicates the upper side of the chamber 5 and the upper side of the reservoir 1 and the atmospheric air, the chamber 5 can be separated from the inlet 5a of the chamber 5. The pressure in the second tube 8 does not change because it flows in the form of a drip into the No. 5, and therefore, the estimation from the pressure value at the inlet pressure measurement unit 4 becomes a hematocrit in which blood is returned as it is. It is a thing.

[0018]

[Effect of the device]

 The extracorporeal blood circulation circuit of the present invention has the above-mentioned structure, so that the concentrated hematocrit that returns blood can be easily estimated by the measurement value measured by the inflow port measurement unit arranged near the inflow port of the blood concentrator. It is epoch-making because it can be widely used for blood collection in surgical operations and the like, and it has a highly practical and highly significant effect.

[0019]

[Brief description of drawings]

FIG. 1 is an overall circuit diagram showing an embodiment of an in vitro blood circulation circuit according to the present invention.

FIG. 2 is a diagram showing an example of a relationship between a pressure measurement value at an inlet pressure measuring unit and a hematocrit at an outlet of a liquid concentrator.

FIG. 3 is a conventional example.

FIG. 4 shows another conventional example.

[0020]

[Explanation of symbols]

 M Living body 1 Reservoir 1a Reservoir outlet 1b Recovery port 1c Filter 1d Atmosphere opening 2 Hemoconcentrator 2a Hemoconcentrator inlet 2b Hemoconcentrator outlet 2c Filtrate discharge part 3 Concentration pump 4 Inlet pressure measurement part 4a Sensor 5 Chamber 5a Chamber inlet 5b Recirculation outlet 5c Living side outlet 6 Blood return pump 7 First tube 7a Branch 8 Second tube 9 Third tube

Claims (1)

[Scope of utility model registration request] 1. A living body comprising a reservoir, a blood concentrator having a filtrate discharging section, a concentrating pump with a constant flow rate, an inlet pressure measuring section of the blood concentrating apparatus, a chamber, and a blood returning pump for the living body. In the external blood circulation circuit, the outlet of the reservoir and the inlet of the blood concentrator are connected by a first tube via a concentration pump, and the concentration pump of the first tube and the inlet of the blood concentrator are connected. A branch portion is provided between the blood concentrator and the inlet pressure measurement unit, and the outlet of the blood concentrator and the inlet of the chamber are connected by a second tube, and a recirculation outlet and a living body side flow are connected to the chamber. An outlet is formed, and the living body side outlet and the living body are connected to each other by a third tube through a variable flow rate blood return pump, and the recirculation outlet and the upper side of the reservoir are directly connected to each other, and the reservoir By forming an atmosphere opening port above Vitro blood circulation circuit in the circulation of the liquid also and maintains the atmospheric release state.