JPH057207U - Blood vessel obturator - Google Patents

Abstract

(57) [Abstract] [Purpose] A blood vessel obstruction device used for such purposes as indwelling in an aneurysm to form a thrombus and preventing blood from flowing into the aneurysm to prevent rupture. It is easy to insert through a catheter and does not protrude from the aneurysm. [Structure] The thin wires 23 of shape memory alloy are entwined in a spherical shape, and in this state, shape memory processing is performed to obtain the blood vessel obturator 21. Next, the blood passage obturator 21 is crushed and reduced in diameter to 1/4 or less. The reduced diameter blood vessel occluding device 21a is inserted into the catheter 29, pushed out by the pusher 31 and inserted into the aneurysm 27 of the blood vessel 25. When inserted into the aneurysm 27, the shape of the aneurysm 27 is filled with the obturator 21 that is warmed by the body temperature and returns to its original shape, and the diameter of the obturator 21 is expanded by four times or more.
Since this blood vessel obstruction device has a short overall length when the diameter is reduced, frictional resistance during insertion is small and it is difficult for the device to protrude from the aneurysm 27.

Description

[Detailed description of the device]

[0001]

[Industrial applications]

  The present invention, for example, is inserted into an aneurysm to fill the inside of the aneurysm and prevent rupture of blood vessels. Blood flow obstruction device.

[0002]

[Prior art]

  For example, when treating an aneurysm, use a guide tube such as a catheter. Insert a vascular obturator into the aneurysm to create a thrombus inside the aneurysm and prevent blood inflow. It prevented the rupture of blood vessels.

[0003]   As an example of such a blood vessel obstruction device, as shown in FIG. A wire rod 3 such as a wire is formed into a coil to form a primary coil 3a. Further, it is known that the secondary coil 3b is formed into a coil shape. In addition, this If necessary, Dacron fibers or the like may be interposed between the wire rods forming the secondary coil 3b. To be done.

[0004]   To insert the blood vessel obstruction device 1 into a blood vessel, as shown in FIGS. A catheter 9 is percutaneously inserted into the blood vessel 5 using a puncture needle to move the blood vessel 5 It is placed in the vicinity of the stenosis 7. Next, insert the blood vessel blocker 1 into the catheter 9, A method of pushing out with a pusher 11 or the like and inserting it into the aneurysm 7 of the blood vessel 5 is To be taken. When the blood vessel obturator 1 is inserted into the catheter 9, the secondary coil 3b Is stretched in the direction of the arrow in FIG. The film 3a is inserted and then inserted.

[0005]   When the blood vessel obturator 1 is thus inserted into the aneurysm 7 of the blood vessel 5, the inserted obturator 1 returns to the state of the secondary coil 3b in the aneurysm 7 by the elastic restoring force. this When a sufficient number of the obturator 1 is inserted by such a procedure, the aneurysm 7 is left inside the obturator 1 The blood inside the aneurysm 7 forms a thrombus, preventing the blood from flowing into the aneurysm. Prevent rupture of 7.

[0006]

[Problems to be solved by the device]

  However, the blood vessel obstruction device 1 including such a coil includes the secondary coil 3b. Entanglement so that when formed, it can fill the space inside the aneurysm 7 Therefore, it is necessary to make the length of the primary coil 3a sufficiently long. Shi Therefore, as shown in FIG. 5, when the secondary coil 3 is inserted into the catheter 9, When b is linearly extended by an external force, the length L of the primary coil 3a is considerably long. Becomes Therefore, it is difficult to insert the catheter 3 into the catheter 9, while the coil 3a is closed. The friction resistance increases when extruding to the outside of the theterl 9, so it can be extruded smoothly. It was not possible to do so, and the patient was sometimes hurt.

[0007]   Further, as shown in FIG. 6, when the obturator 1 is inserted into the aneurysm 7, the insertion procedure is not performed. If it is worse, the primary coil 3a forming the end portion of the coil 1 drops inside the blood vessel 5 outside the aneurysm 7. The blood vessel 5 may be lowered, and a blood clot may be formed in the blood passage of the blood vessel 5. There was a risk that the blood flow inside would stop. Therefore, the doctor in charge inserts the obturator 1. When carrying out the work, carefully proceed while considering the insertion direction of the obturator 1 and the like. It was necessary, which was one reason why the insertion work could not be done quickly.

[0008]   Therefore, the purpose of the present invention is to insert the catheter and to prevent aneurysms. Insertion into the site can be performed quickly and easily, and patients with aneurysms To provide a blood vessel obstruction device that can prevent it from protruding from the part and adversely affecting it is there.

[0009]

[Means for Solving the Problems]

  In order to achieve the above object, the blood vessel obstruction device of the present invention has a shape-memory alloy thin wire formed into a spherical shape. Shape memory processing is performed by intertwining with the The expansion ratio, which is the ratio of the diameter when compressed and the diameter when contracted, is 4 times or more. Is characterized by.

[0010]   Hereinafter, the present invention will be described in more detail.

[0011]   In the present invention, as a material for forming the blood vessel obturator, a material such as TiNi alloy is used. A wire rod made of a shape memory alloy is used. The shape of this wire is round wire, square wire, flat wire. Various things such as lines can be used. The wire diameter of the wire should be 100 μm or less. preferable. This is because if the wire diameter is larger than the above, it becomes difficult to reduce the diameter to a small value. Well Further, the length of the wire is preferably 600 mm or less, more preferably 300 to 600 mm.

[0012]   This shape memory alloy wire rod is rolled up by hand and entangled, and then, In a container like this and keep this condition at 400-500 ℃ for a predetermined time. By restraining aging treatment, it can be memorized in a spherically entangled shape, At low temperatures, it plastically deforms, and when the temperature rises above the transformation point, it becomes a memorized shape. The property of returning can be given. The shape description used in the present invention The transformation point of the alloy is the body temperature so that it can fully restore its shape when placed in a blood vessel. The temperature is preferably lower than that, and more preferably 0 to 20 ° C. Well Further, in the present invention, the spherical shape, which is a shape in which thin wires are entangled, means, for example, a baseball ball. It is not limited to a spherical shape like a ball, but also includes an elliptical spherical shape like a rugby ball. The taste.

[0013]   After the shape memory process is performed in this way, the entangled wire rods are crushed to form, for example, a rod shape. Then, the blood vessel obstruction device of the present invention is obtained by reducing the diameter. In this case, the present invention In the blood vessel obstruction device, the diameter when it is inserted into the body and returned to its shape and the reduced diameter The ratio with the diameter in the state, that is, the expansion ratio, should be 4 times or more. The expansion ratio is above If it is too small, a sufficient blocking effect cannot be obtained, and it is necessary to insert many obturators. It will be important. In addition, the diameter of the blood vessel obstruction device when it is inserted and restored is effective for the affected area. The thickness is preferably about 4 to 10 mm so that it can be effectively blocked.

[0014]   In a preferred embodiment of the present invention, the shape memory is crushed into a predetermined shape to reduce the diameter. The thin alloy wire is covered with a shape-retaining material made of a material that melts in the body. With shape retention material For example, gelatin or the like can be used.

[0015]

[Action]

  The blood vessel obturator of the present invention is a shape memory treatment device in which thin wires of shape memory alloy are entwined in a spherical shape. However, it is crushed and reduced in diameter, so the overall length when diameter is reduced is relatively short. Will be things. Therefore, it can be easily inserted inside a catheter, etc. Easily extrudes by reducing the extrusion resistance when pushing with a pusher etc. Work can be done. In addition, in the conventional obturator consisting of a double coil, Since it is a coil, it is difficult to crush it as it is.

[0016]   Also, when inserted into the body, the diameter of the fine wire expands into a spherical shape, so part of the fine wire There is no need to worry about protruding from the affected area such as an aneurysm. To prevent inconveniences such as blood clots being formed and obstructing blood flow You can

[0017]   Furthermore, in the conventional obturator consisting of double coils, the diameter is reduced to the diameter of the primary coil or less. It is difficult to give it, and even when it is expanded in the body, it is only expanded to the diameter of the secondary coil. On the other hand, in the blood vessel obstruction device of the present invention, the diameter of the crushed and reduced diameter is It is possible to increase the ratio with the diameter when the shape is restored in the body, that is, the expansion ratio to 4 times or more. It is easy, and even if the total length in the reduced diameter state is relatively short, the affected area such as an aneurysm can be effectively treated. Can be occluded.

[0018]   On the other hand, in a preferred embodiment of the present invention, a shape that is crushed into a predetermined shape and reduced in diameter is used. The outer shape of the thin wire of the shape memory alloy was covered with a shape-retaining material made of a material that melts inside the body As a result, when inserting it through the catheter, it makes the slide better and It is possible to prevent the diameter from expanding due to body temperature during insertion. Also inserted into the body Since the shape-retaining material dissolves after being crushed, it does not hinder the expansion of the obturator.

[0019]

【Example】

  FIG. 1 shows an embodiment of the blood vessel obstruction device of the present invention.

[0020]   In this blood vessel obstruction device 21, thin wires 23 of shape memory alloy are rolled and entangled in a spherical shape, Shape memory processing is performed in that state. The thin wire 23 of shape memory alloy has a diameter of 10 Those having a size of 0 μm or less are preferably used. The length of the thin wire 23 is Depending on the diameter of the blood vessel obturator 21 in the open state and the density of the wire material forming the obturator 21. However, it is preferably 600 mm or less, more preferably 300 to 600 mm. It is considered as a degree. The shape of the blood passage obturator 21 in the state where the shape is restored is close to a spherical shape. It is preferable that the diameter is 4 to 10 mm.

[0021]   The blood vessel obturator 21 has a shape close to a sphere as a whole, so that the coil It is possible to secure a sufficient volume even if the total length A is shortened as compared with a blood vessel obturator having a shape. it can.

[0022]   In FIG. 2, the blood vessel obturator 21 is manually operated at a temperature below the transformation point of the shape memory alloy. The blood path obstruction device 21a that is crushed and reduced in diameter is shown. In this case, reduce the diameter The diameter when the shape is memorized is not more than 1/4 of the diameter of the spherical body when the shape is memorized. To do. The blood flow obstruction device 21 is thus crushed and reduced in diameter in the catheter. Inserted in. Since the blood passage obturator 21 has a spherical shape as described above, Even when crushed and reduced in diameter, there is little difference between the total length A when expanding and the total length A'when reducing diameter. Even if the diameter is reduced, the total length A'can be kept short. For this reason, The insertion work can be facilitated. In addition, when reducing the diameter, The diameter B is set so that it can be inserted into the catheter, preferably 0.5 to 3 It is about mm.

[0023]   As a preferred example of the present invention, a shape memory alloy having a wire diameter of 0.08 mm and a length of 300 mm. Using a thin wire consisting of, the shape is entangled to form a spherical body with a diameter of 8 mm. The spherical body was crushed and the diameter was reduced to 1.17 mm. It was possible to restore the shape to a spherical body having a diameter of 8 mm by heating it once. You That is, it was possible to make the expansion ratio 6 times or more.

[0024]   Next, a method of treating an aneurysm using this blood vessel obstruction tool will be described.

[0025]   First, a catheter 29 is percutaneously inserted into the blood vessel 25 using a puncture needle, As shown, the tip of the catheter 29 reaches the aneurysm 27. Next Insert the reduced diameter obturator 21a into the catheter 29, and displace the placement location. The catheter 29 is held by hand so that the aneurysm 27 is removed by the pusher 31. The obturator 21a is pushed in. At this time, since the total length A'of the obturator 21a is short, The insertion resistance is low and the insertion work can be done smoothly. Note that this example In, a coiled guide wire is used as the pusher 31.

[0026]   When the blood tract obturator 21a is pushed out into the aneurysm 27, a thin shape memory alloy is used. The state of the obturator 21 having a substantially spherical shape in which the wire 23 is warmed by the body temperature and returns to its shape. And the inside of the aneurysm 27 is filled. If the aneurysm 27 is large, this The operation is repeated to insert a plurality of obturators 21 to close the aneurysm 27. Blood blockage The tool 21 has a short overall length and is formed into a spherical shape as a whole. Since the thin wires 23 formed are intertwined at random, the obturator 21 or the thin wires 2 3 does not have to worry about hanging in the blood vessel 25, and thrombus can be formed in the flow path of the blood vessel 25. Can be prevented.

[0027]   When the aneurysm 27 is buried in the blood passage obstruction device 21 in this manner, the blood in the aneurysm 27 is Creates a blood clot to prevent the inflow of blood and prevent the aneurysm 27 from rupturing.

[0028]   The outer circumference of the reduced diameter obturator 21a is made of a material such as gelatin that dissolves in the body. It may be covered with a quality shape-retaining material. In this way, the outer shape of the obturator 21a is shaped by the shape-retaining material. When covered with a material, the condition of the reduced diameter obturator 21a can be easily maintained and the catheter It can be easily inserted into the blood vessel 25 and can be inserted during the insertion work into the blood vessel 25. It is possible to prevent the obturator 21a from expanding in diameter in the tether 29.

[0029]   Further, the blood vessel obstruction device of the present invention is not limited to the above-mentioned application for placement in an aneurysm. In order to prevent bleeding in the event of a traffic accident, a treatment to block a specified part of a blood vessel It can also be used as a tool.

[0030]

[Effect of device]

  As described above, according to the vascular obturator of the present invention, the overall length of the obturator is shortened. Since frictional resistance can be reduced, insertion work into the catheter and cutting Pushing out from the tell can be done easily.

[0031]   In addition, by setting the expansion ratio to 4 times or more, the occluding effect when inserted into a blood vessel Can be increased.

[0032]   Also, when the diameter is expanded, the shape is spherical as a whole, and the thin wires are intertwined. Therefore, there is no need to worry that the end of the obturator or the end of the thin wire will protrude outside the affected area, and blood will It is possible to prevent solidification outside the part.

[0033]   Furthermore, if the outer circumference of the reduced diameter obturator is covered with a shape-retaining material that can dissolve in the body, , The reduced shape can be retained to facilitate the insertion work into the catheter. At the same time, it is possible to prevent the obturator from expanding in the course of insertion into the blood vessel. Wear.

[Brief description of drawings]

FIG. 1 is a front view showing an embodiment of the blood vessel obstruction device of the present invention.

FIG. 2 is a front view showing a state in which the blood vessel obstruction device shown in FIG. 1 has a reduced diameter.

FIG. 3 is an explanatory view showing a state in which the blood vessel obstruction device of the present invention is inserted into an aneurysm.

FIG. 4 is a perspective view showing a state in which the conventional blood vessel obturator has returned to its original shape.

FIG. 5 is an explanatory view showing a conventional method for inserting a blood vessel obstruction device into a blood vessel.

FIG. 6 is an illustration showing a state in which the same obturator is inserted into an aneurysm.

[Explanation of symbols]

21 Blood vessel blockers 21a Blood circuit blocker 23 Fine wire of shape memory alloy 25 blood vessels 27 aneurysm 29 catheter 31 Pusher

Claims (2)

[Scope of utility model registration request] 1. A shape memory alloy fine wire is entangled in a spherical shape for shape memory treatment, and the spherical body is crushed to reduce its diameter,
A blood vessel obstruction device characterized in that an expansion ratio, which is a ratio of a diameter when the shape is restored and a diameter when the diameter is reduced, is set to 4 times or more. 2. The thin wire of the shape-memory alloy whose diameter is reduced,
3. A shape-retaining material made of a material that dissolves in the body.
The blood vessel obstruction described.