JPH0564064B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a deodorant using a composite powder composed of a synthetic resin and hydroxyapatite as an active deodorizing substance.

BACKGROUND TECHNOLOGY Many explanations for the causes of body-derived bad odors such as armpit odor, sweat odor, foot odor, hair odor, menstrual odor, etc. are caused by bacterial decomposition of sweat [for example, Labows and Kligman et al. "J.
Soc.Cosmet.Chem., 34. (1982), p. 193]. There are many products on the market to treat these odors, many of which contain antiperspirants, disinfectants, masking agents, adsorbents, and the like. Most antiperspirants that reduce the amount of sweat are astringent aluminum compounds, and aluminum hydroxychloride is commonly used. On the other hand, hexachlorophene and various quaternary ammonium compounds are often used as disinfectants to inhibit the growth of bacteria that cause bad odors. Further, as a masking agent, a substance having a pleasant odor such as eugenol is used.
Currently, these antiperspirants, disinfectants, and masking agents are blended into products alone or in arbitrary combinations.

Problems to be Solved by the Invention Incidentally, antiperspirants have the effect of reducing sweat, which is the source of sweat odor components, but it is impossible from a physiological perspective to completely control sweating. ,
Also, considering its mechanism of action, it has the disadvantage that it cannot control sweat odor that has already occurred.

On the other hand, disinfectants that decompose sweat and inhibit the growth of bacteria that cause bad odors have been pointed out to have safety issues, and have the disadvantage that they cannot be formulated in sufficient concentrations to be effective.

Furthermore, masking agents have the disadvantage that they may mix with sweat odor and generate unpleasant odors.

Therefore, the above-mentioned conventional deodorants containing antiperspirants, disinfectants, and masking agents have a problem in that they are not fully satisfactory in terms of effectiveness, safety, and usability.

Therefore, the present inventors conducted research to solve the problems of the conventional technology, and as a result, it was possible to solve the problems by using a composite powder made of synthetic resin and hydroxyapatite as a deodorizing active substance. This discovery led to the present invention.

Means for Solving the Problems That is, the present invention provides a deodorant using a composite powder made of a synthetic resin and hydroxyapatite as an active deodorizing substance. , external deodorants such as powders, creams, and stickers, as well as
It also includes forms such as shoe soles and household deodorants.

The present invention will be explained in detail below.

Examples of the synthetic resin used as a component of the deodorizing active substance in the present invention include nylon,
Examples include polyvinyl alcohol, polyvinylidene chloride, polyvinyl chloride, polyester, polyacrylonitrile, polyethylene, polypropylene, polycyanide vinylidene, polyurea, polystyrene, polyurethane, polyfluoroethylene, and the like. Preferred are nylon, polyethylene, and polypropylene, and particularly preferred is nylon.

The deodorant according to the present invention is composed of the above-mentioned synthetic resin and hydroxyapatite, and a composite powder is used as the deodorizing active substance, preferably in a concentration of 0.1 to 60% in the deodorant.
% by weight. As other components of the deodorant, any conventionally known components can be blended.

Examples of such ingredients include avocado oil, almond oil, olive oil, grapeseed oil, sesame oil, sasanqua oil, safflower oil, soybean oil, camellia oil, corn oil, rapeseed oil, persic oil, castor oil, Fats and oils such as sunflower oil, cottonseed oil, peanut oil, cacao oil, palm oil, coconut oil, beef tallow, fish oil, hydrogenated oil, turtle oil, pork oil, mink oil, egg yolk oil; spermaceti, ceramics, beeswax,
Waxes such as lanolin, liquid lanolin, carnauba wax, and candelilla wax; hydrocarbons such as liquid paraffin, liquid polyisoptylene, squalane, pristane, petrolatum, paraffin, and ceresin; succinic acid, tartaric acid, citric acid, undecylenic acid, lauric acid, myristic acid, Fatty acids such as palmitic acid, stearic acid, isostearic acid, oleic acid, linoleic acid, ricinoleic acid, behenic acid; ethanol, isopropanol, lauryl alcohol, cetanol, 2-hexyldecanol, stearyl alcohol, isostearyl alcohol,
Alcohols such as oleyl alcohol and lanolin alcohol; polyhydric alcohols such as ethylene glycol, diethylene glycol monoethyl ether, triethylene glycol, polyethylene glycol, propylene glycol, 1,3-butylene glycol, glycerin, and batyl alcohol; glucose, sucrose, and lactose , xylitol, sorbitol, mannitol, maltitol, and other sugars; diisoprobyl adipate, hexyldecyl isostearate, cetyl isooctanoate, oleyl oleate, decyl oleate, lanolin acetate, butyl stearate, isoprobyl myristate, diethyl phthalate, Esters such as hexyl laurate; metal soaps such as aluminum stearate, magnesium stearate, zinc stearate;
Natural water-soluble polymer compounds such as gum arabic, sodium alginate, casein, carrageenan, gum karaya, agar, quince seed, gelatin, dextrin, starch, tragacanth, and pectin; semi-synthetic polymers such as propylene glycol alginate, ethyl cellulose, crystalline cellulose, and methyl cellulose Molecular compounds; synthetic polymer compounds such as carboxyvinyl polymer, polyvinyl methyl ether, methoxyethylene maleic anhydride copolymer; interfaces of dialkyl sulfosuccinates, alkylaryl sulfonates, higher alcohol sulfate ester salts, phosphate ester salts, etc. Activator; Preservatives such as ethyl paraoxybenzoate and methyl paraoxybenzoate; vitamin A, vitamin D, vitamin E,
Vitamins such as vitamin K; Hormones such as estradiol, ethinyl estradiol, cortisone; Red No. 2, Blue No. 1, Red No. 202, Yellow 201
Organic pigments such as No. 204, Green No. 204, and Purple No. 201; Inorganic pigments such as aluminum powder, talc, kaolin, bentonite, mica, titanium mica, Vencara, and calamine; Ultraviolet absorbers such as urocanic acid and siquinosate; Allantoin and Aero powder , anti-inflammatory agents such as fluorocarbon 11, fluorocarbon 12, fluorocarbon 21, fluorocarbon 22, fluorocarbon 113, fluorocarbon 114, fluorocarbon C318, methyl chloride, methylene chloride, isobutane, propellants such as carbon dioxide, purified water, etc. can.

Other additives that can optionally be incorporated into the deodorant according to the invention include, for example, aluminum hydroxychloride, aluminum chloride,
Aluminum sulfate, basic aluminum bromide, aluminum phenolsulfonic acid, tannic acid,
Antiperspirants such as aluminum naphthalene sulfonic acid, basic aluminum iodide, 3,4,4-torclocarbanilide (TCC), benzalkonium chloride, benzethonium chloride, alkyltrimethylammonium chloride, resorcinol, phenol, solevic acid , salicylic acid, bactericides such as hexachlorophene, dia incense, skatole, lemon oil, lavender oil, absolute, diasmine,
Examples include masking agents such as vanillin, benzoin, benzyl acetate, and menthol.

The composite powder consisting of synthetic resin and hydroxyapatite, which is blended as an essential component in the deodorant according to the present invention, can be produced by any method, but the synthetic resin powder is used as the core powder, and the core powder is Preferably, the body is substantially completely coated with hydroxyapatite powder having an average particle size of 1/5 or less of that of the synthetic resin powder.

The ratio of the amount of synthetic resin powder to hydroxyapatite powder used can be arbitrarily changed depending on the product form, and is not particularly limited, but it is preferable that the weight ratio of hydroxyapatite to synthetic resin is 5 to 60%. In addition, the particle size of the synthetic resin powder is
Although not particularly limited, it is preferably about 0.5 to 20 μm when used in a deodorant applied to the skin.

The composite powder incorporated as the deodorant active substance in the deodorant according to the invention can be produced using conventionally known solids or any conventional mixing technique. That is, for example, any mixing machine such as a rotary ball mill, a vibrating ball mill, a planetary ball mill, a sand mill, an attritor, etc. can be used, and the ball-shaped mixing medium of these ball mills can be used to form small particles with an average particle size of 5 mm or less. For example, when using a powder with a diameter of ) is preferable because a composite powder with excellent properties can be obtained.

EXAMPLES Hereinafter, the present invention will be explained in more detail by giving an example of a deodorant using the composite pulverized compound obtained from the synthetic resin hydroxyapatite according to the present invention as a deodorizing active substance. It goes without saying that the scope is not limited to these implementation orders. The test method is as follows.

(Deodorization test method) Panel 6 of healthy men who are aware of having armpit odor
A deodorant compounded with a composite powder according to the present invention was tested using the same name. The test product was applied directly to the test subject's armpit only four times, once in the morning and once in the afternoon, for two days. The area under the armpit where it is not applied is used as a control.

Judgment is based on the following five-stage criteria, namely: 0: No underarm odor 1: Slight underarm odor 2: There is a distinct underarm odor. 3: Armpit odor is bad 4: Very strong armpit odor According to.

Example 1 Hydroxyapatite (specific surface area 70.4m ² /
40 g (manufactured by Sumitomo Chemical) and 50 g of nylon (12 nylon balls, average particle size 5 μm, nylon SP-500, manufactured by Nikko Rikagaku Sangyo) were uniformly mixed for 10 minutes at room temperature using a Henschel mixer manufactured by Mitsui Miike Seisakusho FM10B. The mixture was mixed to obtain a composite powder. Next, a deodorizing powder having the following composition was prepared using this composite powder. Ingredient weight% Composite powder 40.0 Talc 60.0 When a deodorization test was conducted using the above powder according to the method described above, it was found that after the start of the test, the underarm odor intensity in the test area was dangerous compared to the control area. rate 5
It decreased by a significant percentage.

Example 2 70 ml of sintered alumina holes with an average diameter of 2 mmφ, 20 g of hydroxyapatite (specific surface area 70.4 m ² /g) and 80 g of nylon (average particle size) were placed in a centrifugal rotating ball mill.
5 μm) and ball milling was performed for 30 minutes.

Using this composite powder, an aerosol deodorizing spray having the following composition was prepared. Ingredient weight% Freon 11 76.8 Freon 12 19.2 Composite powder 1.5 Talc 1.5 Isopropyl myristate 0.5 San-S Ball 70 0.5 In the practical test using this spray, after the test started, as shown in Figure 1, none of the panels The intensity of armpit odor in the test area was significantly reduced compared to the control area with a risk rate of 5%.

When the composite powder of the aerosol deodorant spray of Example 2 was replaced with nylon and hydroxyapatite powder, the changes over time in the axillary odor intensity of the aerosol deodorant spray were as shown in FIGS. 2 and 3, respectively. On the other hand, the change over time in the underarm odor intensity of the aerosol deodorizing spray of Example 2 was as shown in FIG.

Example 3 Hydroxyapatite was added under the same conditions as Example 2.
40g and 60g of nylon were ball milled. Using the obtained composite powder, an aerosol deodorizing spray having the following composition was prepared. Ingredient weight% Freon 11 76.8 Freon 12 19.2 Composite powder 1.0 Talc 2.0 Isopropyl myristate 0.5 Sun-Espol 70 0.5 When we started a practical test using this spray, after the start of the test, the strength of armpit odor in the test area of all panels decreased. There was a significant decrease in the risk rate of 5% compared to the control area.

Example 4 Hydroxyapatite was added under the same conditions as Example 2.
30g and 70g of nylon were subjected to pole mill treatment. A deodorizing powder having the following composition was prepared using the resulting composite powder. Ingredient weight% Composite powder 50.0 Talc 50.0 When a practical use test was conducted using this deodorizing powder, after the start of the test, the underarm odor intensity in all panel test areas was significantly higher than that in the control area with a risk rate of 5%. Diminished.

Example 5 Hydroxyapatite was added under the same conditions as Example 2.
20g and 80g of nylon were ball milled. A deodorizing powder having the following composition was prepared using the produced composite powder. Ingredient weight% Composite powder 30.0 Talc 70.0 With the use of this powder, the intensity of armpit odor decreased over time in all panels, supporting its effectiveness.

[Brief explanation of the drawing]

FIG. 2 is a graph showing the change over time in the intensity of armpit odor in the test area and the control area in an actual use test using the aerosol deodorant spray in which the composite powder in the deodorant spray of Example 2 was replaced with nylon. ,
FIG. 3 is a graph showing the change in armpit odor intensity over time when the composite powder in the deodorant spray of Example 2 is replaced with zinc oxide, and FIG. 1 is a graph showing the effect of the aerosol deodorant spray in Example 2. This is what is shown.

Claims (1)

[Claims] 1. A deodorant characterized by containing a composite powder composed of a synthetic resin and hydroxyapatite as a deodorizing active substance.