JPH05269136A - Ventricle capacity measuring method and measuring catheter - Google Patents
Ventricle capacity measuring method and measuring catheterInfo
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- JPH05269136A JPH05269136A JP4065102A JP6510292A JPH05269136A JP H05269136 A JPH05269136 A JP H05269136A JP 4065102 A JP4065102 A JP 4065102A JP 6510292 A JP6510292 A JP 6510292A JP H05269136 A JPH05269136 A JP H05269136A
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- JP
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- Prior art keywords
- ventricle
- catheter
- measuring
- electrodes
- balloon
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Measuring And Recording Apparatus For Diagnosis (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は、心臓の心室の容積を正
確に測定する方法及びこの測定に用いるカテ−テルに関
する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for accurately measuring the volume of the ventricle of the heart and a catheter used for this measurement.
【０００２】[0002]
【従来の技術】拍動する生体心臓の心室の収縮及び拍出
特性を、心室の内圧や容積との関係から解析しようとす
る試みは古くからなされている。更に近年は、心室の内
圧や容積について、心臓の力学的機能を解析する上で極
めて有効な因子であるとして見直されている。しかし
て、心室の内圧の測定に関しては、近年の医療機器の著
しい進歩により、高精度に連続して測定が可能となって
いる。しかし一方、心室内の血液の容積の測定に関して
は、今まで、エコ−法、アンギオグラフィ法、ＭＲＩ法
等が採用されているが、これらの測定方法は非常に手数
が掛り、また手数を掛けてもその割には精度が上がら
ず、しかも測定装置が高価であるといった問題点があ
る。そして、この心室容積の測定の困難性が、心臓機能
の解析に最大の障害となっていた。2. Description of the Related Art Attempts have been made for a long time to analyze the contraction and ejection characteristics of the ventricle of a pulsating living heart from the relationship with the internal pressure and volume of the ventricle. Furthermore, in recent years, the internal pressure and volume of the ventricle have been re-examined as an extremely effective factor in analyzing the mechanical function of the heart. However, with respect to the measurement of the internal pressure of the ventricle, it has become possible to measure the internal pressure of the ventricle continuously with high accuracy due to the remarkable progress of medical devices in recent years. On the other hand, on the other hand, regarding the measurement of the volume of blood in the ventricle, the eco-method, angiography method, MRI method, etc. have been adopted up to now, but these measurement methods are very troublesome and time-consuming. However, there is a problem in that the accuracy is not improved and the measuring device is expensive. The difficulty in measuring the ventricular volume has been the greatest obstacle to the analysis of heart function.
【０００３】そこで、近年、心室の容積の測定に、コン
ダクタンスカテ−テルシステムを用いる方法が提案され
ている。このコンダクタンスカテ−テルシステムを用い
た測定法は、リアルタイムに連続して心室容積を測定す
ることができる利点があり、今後、医学や医療の現場で
利用され、心臓機能の解析、心臓病の治療方針の決定及
び心臓薬の開発等、医学及び医療の発展に貢献するもの
と期待される。Therefore, in recent years, a method using a conductance catheter system for measuring the volume of the ventricle has been proposed. The measurement method using this conductance catheter system has the advantage that it can continuously measure the ventricular volume in real time, and will be used in the medical and medical fields in the future to analyze heart function and treat heart disease. It is expected to contribute to the development of medicine and medical care, such as policy decisions and development of cardiac drugs.
【０００４】しかし、コンダクタンスカテ−テルシステ
ムを用いた心室容積の測定法には、測定値が測定対象の
心室の形状に影響されて個体差が生じ、正確に測定する
ことが困難であると言う問題点があった。However, in the method of measuring ventricular volume using the conductance catheter system, the measured value is affected by the shape of the ventricle to be measured, causing individual differences, and it is difficult to measure accurately. There was a problem.
【０００５】[0005]
【発明が解決しようとする課題】本発明は、コンダクタ
ンスカテ−テルシステムを用いた心室容積の測定法にお
ける上記の問題点を解消し、心室の形状に影響されるこ
とが少なく、正確に測定できる測定方法、及びその測定
に使用するカテ−テルを提供することを目的とする。DISCLOSURE OF THE INVENTION The present invention solves the above problems in the method of measuring the volume of a ventricle using the conductance catheter system, is less affected by the shape of the ventricle, and can be accurately measured. It is intended to provide a measurement method and a catheter used for the measurement.
【０００６】[0006]
【課題を解決するための手段】すなわち本発明の一つ
は、複数の電極を埋設したカテ−テルを心室内に挿入
し、１対又は２対以上の電極間に微弱な交流電流を定常
的に流し、残りの電極間を流れる微弱電流のインピ−ダ
ンス変化を継続的に計測して心室容積を測定するコンダ
クタンスカテ−テルシステム測定法において、心室内で
電気絶縁性のバル−ンを膨張させ、その際のバル−ンの
膨張容量と膨張前後の心室容積測定値の差との比を用い
て心室容積測定値を更正することを特徴とする心室容積
測定方法であり、またもう一つは、複数の電極を埋設し
たカテ−テルを心室内に挿入し、１対又は２対以上の電
極間に微弱な交流電流を定常的に流し、残りの電極間で
微弱電流により生じたインピ−ダンス変化を継続的に計
測して心室容積を測定するコンダクタンスカテ−テルシ
ステムに用いるカテ−テルであって、該カテ−テルは電
気絶縁性の膨張自在のバル−ンを有することを特徴とす
る心室容積測定用カテ−テルである。Means for Solving the Problems That is, one of the present invention is to insert a catheter having a plurality of electrodes embedded therein into a ventricle so that a weak alternating current is constantly applied between one pair or two or more pairs of electrodes. In the conductance catheter system measurement method in which the impedance change of the weak current flowing between the remaining electrodes is continuously measured to measure the ventricular volume, the electrically insulating balloon is expanded in the ventricle. , A ventricular volume measurement method characterized in that the ventricular volume measurement value is calibrated using a ratio of the expansion volume of the balloon at that time and the difference between the measurement values of the ventricle volume before and after expansion, and another is , A catheter with a plurality of electrodes embedded therein is inserted into the ventricle, and a weak alternating current is constantly applied between one or more pairs of electrodes, and impedance is generated between the remaining electrodes by the weak current. Ventricular volume is measured by continuously measuring changes That a conductance catheter - catheter used ether system - a ether, the catheter - ether is of electrically insulating inflatable Val - it is ether - ventricular volume measurement catheter characterized by having a down.
【０００７】本発明について詳しく説明する。コンダク
タンスカテ−テルシステムを用いた心室容積の測定法
は、心室内の血液の電気伝導性を利用する測定法であ
る。この方法で用いるカテ-テルは、その先端の心室内
に挿入される部分に複数個の電極が埋設されている。図
３は従来から用いられているカテ-テルの一例を示す斜
視図である。図３において、１は中空のカテ−テルチュ
−ブである。２はカテ−テルの先端、３〜１０はカテ−
テルに埋設された電極であり、この図３の例においては
４対、計８個の電極が埋設されている。それぞれの電極
の配線はカテ−テルの中を通り測定器に接続されてい
る。The present invention will be described in detail. The measuring method of the ventricular volume using the conductance catheter system is a measuring method utilizing the electric conductivity of blood in the ventricle. In the catheter used in this method, a plurality of electrodes are embedded in the part of the tip inserted into the ventricle. FIG. 3 is a perspective view showing an example of a conventionally used catheter. In FIG. 3, reference numeral 1 is a hollow catheter tube. 2 is the tip of the catheter, 3-10 is the catheter
The electrodes are embedded in the tell, and in the example of FIG. 3, four pairs, that is, eight electrodes in total are embedded. The wiring of each electrode is connected to a measuring instrument through a catheter.
【０００８】図３の８個の電極を埋設したカテ−テルの
先端部を大動脈弁から心室に挿入し、心尖部に向かって
導入して心室内に留置する。そして、８個の電極のうち
の両端電極３、１０間に２０ＫＨｚ、３０μＡの微弱電
流を定常的に流す。この定常微弱電流により心室内血液
を媒体として三次元的な電場が形成される。この電場の
変化すなわちコンダクタンス変化を、中間の各隣接電極
間、すなわち４−５間、５−６間、６−７間、７−８
間、８−９間及び９−１０間の５区間で連続的に計測す
る。The tip of the catheter in which the eight electrodes shown in FIG. 3 are embedded is inserted from the aortic valve into the ventricle, introduced toward the apex of the heart, and left in the ventricle. Then, a weak current of 20 KHz and 30 μA is constantly applied between the electrodes 3 and 10 at both ends of the eight electrodes. The steady weak current forms a three-dimensional electric field using blood in the ventricle as a medium. This change in electric field, that is, the change in conductance, is changed between adjacent intermediate electrodes, that is, between 4-5, 5-6, 6-7, and 7-8.
, 8-9 and 9-10 are continuously measured.
【０００９】この際、時々刻々変化する心室の容積と計
測されたコンダクタンス値との間には、次式の関係が成
立する。 Ｖ（ｔ）＝Ｃ×ρ×Ｌ2×Ｇ（ｔ）＋Ｖｃ （１） （ただし、式中、Ｖ（ｔ）は時刻ｔにおける心室容積、
Ｃは定数、ρは血液抵抗値、Ｌは電極間距離、Ｇ（ｔ）
は時刻ｔにおけるコンダクタンス、Ｖｃは補正値を表
す。）At this time, the relationship of the following equation is established between the volume of the ventricle and the measured conductance value, which change from moment to moment. V (t) = C × ρ × L 2 × G (t) + Vc (1) (where V (t) is the ventricular volume at time t,
C is a constant, ρ is a blood resistance value, L is a distance between electrodes, and G (t)
Represents a conductance at time t, and Vc represents a correction value. )
【００１０】したがって、心室容積Ｖ（ｔ）は、電極間
距離Ｌを決め、また血液抵抗値ρを実測しておくと、上
式（１）を用いてコンダクタンスの計測値Ｇ（ｔ）から
算出することができる。現在市販されている測定器にお
いては、上式における定数Ｃを予め定め、また実測した
電極間距離Ｌ及び血液抵抗値ρ並びに補正値Ｖｃを入力
しておくと、Ｇ（ｔ）及びＶ（ｔ）が自動的に表示され
るようになっている。Therefore, if the inter-electrode distance L is determined and the blood resistance value ρ is actually measured, the ventricular volume V (t) is calculated from the conductance measured value G (t) using the above equation (1). can do. In a commercially available measuring instrument, if the constant C in the above formula is predetermined and the measured interelectrode distance L, blood resistance value ρ, and correction value Vc are input, G (t) and V (t ) Is automatically displayed.
【００１１】しかして、このコンダクタンスカテ−テル
システム測定法において前述したように問題点がある。
それは上式の定数Ｃが、測定対象である心室の形状によ
り変化し、その個体差によりバラツキがあって、おおよ
そ０．８〜１．２の範囲で変化し、そのため測定精度を
確保することが困難なことである。すなわち、この定数
Ｃについて、個体それぞれの適切な値を決めることがで
きないため、心室容積を正確に測定することが困難であ
った。However, this conductance catheter system measuring method has a problem as described above.
This is because the constant C in the above equation changes depending on the shape of the ventricle to be measured, and there are variations due to individual differences, and changes in the range of approximately 0.8 to 1.2, so that measurement accuracy can be secured. It's difficult. That is, it is difficult to accurately measure the ventricular volume because it is not possible to determine an appropriate value for this constant C for each individual.
【００１２】本発明は、これら問題点を解消した測定法
である。本発明は、従来コンダクタンスカテ−テルシス
テムで使用するカテ−テルに、更に電気絶縁体で形成さ
れた膨張自在のバル−ンを備えたカテ−テルを用いて測
定する。図１は本発明で用いるカテ−テルの一例の斜視
図である。図１において、符号１〜１０は前記図３と同
じである。１１は電気絶縁体で形成された膨張自在のバ
ル−ンである。このバル−ン１１は、カテ−テルの電極
６、電極７間に固定されている。そして、カテ−テル１
の電極６と電極７の間には孔１２があけられており、こ
の孔１２には細い中空チュ−ブが接続され、この中空チ
ュ−ブはカテ−テルの中を通ってその末端は液体ポンプ
に接続されている。なお、容量の大きなバル−ンを取り
付けたい場合は、電極６と電極７の間隔を拡げ大きなバ
ル−ンを固定できるようにするとよい。The present invention is a measuring method which solves these problems. In the present invention, a catheter used in a conventional conductance catheter system is further measured by using a catheter provided with an expandable balloon formed of an electric insulator. FIG. 1 is a perspective view of an example of a catheter used in the present invention. 1, reference numerals 1 to 10 are the same as those in FIG. Reference numeral 11 denotes an expandable balloon formed of an electric insulator. This balloon 11 is fixed between the electrodes 6 and 7 of the cathode. And Caterel 1
A hole 12 is bored between the electrode 6 and the electrode 7 of the same, and a thin hollow tube is connected to the hole 12, and this hollow tube passes through a catheter and its end is a liquid. Connected to pump. In addition, when it is desired to attach a balloon having a large capacity, it is advisable to widen the gap between the electrodes 6 and 7 so that the large balloon can be fixed.
【００１３】しかして、カテ−テルの先端部を心室内に
導入した後、ポンプを作動させ中空チュ−ブを通して例
えば生理食塩水を送ることにより、随時バル−ン１１を
膨張させることができる。図２はこのバル−ン１１を膨
張させた状態を示している。また、カテ−テルと共にバ
ル−ンを心室に入れるには、カテ−テルの先端部に、電
気絶縁体で形成された膨張自在のバル−ンを紐等で固定
し、このバル−ンに、バル−ン内に生理食塩水を送るた
めの細い中空チュ−ブを取り付けてもよい。After introducing the distal end of the catheter into the ventricle, however, the pump can be operated to feed physiological saline, for example, through the hollow tube to expand the balloon 11 at any time. FIG. 2 shows a state in which the balloon 11 is expanded. In addition, in order to put the balloon together with the catheter into the ventricle, an inflatable balloon formed of an electrical insulator is fixed to the distal end of the catheter with a string or the like, and to this balloon, A thin hollow tube may be fitted for delivering saline into the balloon.
【００１４】本発明においては、上記したバル−ンを有
するカテ−テルを体内に挿入し、複数対の電極を埋設し
たカテ−テル先端部を心室内に導入留置し、両端の電極
間に微弱電流を流し、この微弱電流によって一定の電場
が形成されている心室血液中で、上記のバル−ン内に中
空チュ−ブを通じて、或る量の例えば生理食塩水Ｘｍｌ
を送り出しバル−ンを膨張させる。この際、まず或る程
度バル−ンを膨張させておき、次いでＸｍｌの生理食塩
水を送り、更にバル−ンを膨張させてもよい。In the present invention, the catheter having the above-mentioned balloon is inserted into the body, and the distal end of the catheter in which a plurality of pairs of electrodes are embedded is introduced and left in the ventricle, and the electrodes at both ends are weakly weakened. In the ventricular blood in which a constant electric field is formed by passing a current through the weak current, a certain amount of, for example, Xml of physiological saline is passed through the hollow tube in the balloon.
To inflate the balloon. At this time, the balloon may be inflated to some extent first, and then X ml of physiological saline may be fed to further inflate the balloon.
【００１５】このようにバル−ンを膨張させると、その
バル−ンの膨張容量Ｘｍｌ分だけ血液中に電気的な空洞
が生じ、またこの空洞に対応する容積分Ｘｍｌだけ心室
の血液容積が減少する。このバル−ンを膨張させる前及
び膨張させた後のそれぞれの容積の測定値（読み値）Ｖ
（ｔ）、Ｖ’（ｔ）を読み取り、この両者の読み取り値
の差とバル−ン自体の膨張容積量Ｘｍｌとを対比する。
この対比により、測定対象である心室の形状に適合する
補正定数Ｃｒを求めることができる。そしてここで得た
定数Ｃｒを用いて心室容積を測定することによって、正
確な測定を行うことができる。When the balloon is expanded in this way, an electrical cavity is created in the blood by the expansion volume Xml of the balloon, and the blood volume of the ventricle is reduced by the volume Xml corresponding to this cavity. To do. Measured value (reading value) V of each volume before and after expansion of this balloon
(T) and V '(t) are read, and the difference between the two readings is compared with the expansion volume Xml of the balloon itself.
From this comparison, the correction constant Cr that matches the shape of the ventricle to be measured can be obtained. Accurate measurement can be performed by measuring the ventricular volume using the constant Cr obtained here.
【００１６】この点について更に詳しく説明する。今、
上記したバル−ンを膨張させる前の測定器の心室容積と
コンダクタンスの測定値（読み値）がそれぞれＶ（ｔ）
及びＧ（ｔ）であり、また、バル−ン内にＸｍｌの生理
食塩水をいれて膨張させた後の測定器の心室容積とコン
ダクタンスの測定値（読み値）がそれぞれＶ'（ｔ）及
びＧ'（ｔ）であったとすると、前述の式から、 Ｖ（ｔ）＝Ｃ×ρ×Ｌ2×Ｇ（ｔ）＋Ｖｃ （１） Ｖ'（ｔ）＝Ｃ×ρ×Ｌ2×Ｇ'（ｔ）＋Ｖｃ （２） である。そして、バル−ン膨張前後の心室容積測定値
（読み値）の差をΔＶ(ｔ)とすると、ΔＶ（ｔ）は、式
（１）、（２）から、 ΔＶ（ｔ）＝Ｖ（ｔ）−Ｖ'（ｔ） ＝（Ｃ×ρ×Ｌ2）（Ｇ（ｔ）−Ｇ'（ｔ）） （３） である。This point will be described in more detail. now,
The measured values (reading values) of the ventricle volume and conductance of the measuring instrument before the balloon is inflated are V (t), respectively.
And G (t), and the measured values (reading values) of the ventricular volume and conductance of the measuring device after the physiological saline of X ml was inflated in the balloon and expanded were V ′ (t) and If G ′ (t), then from the above equation, V (t) = C × ρ × L 2 × G (t) + Vc (1) V ′ (t) = C × ρ × L 2 × G ′ (T) + Vc (2). Then, assuming that the difference between the measured ventricular volume (reading value) before and after balloon expansion is ΔV (t), ΔV (t) can be calculated from Equations (1) and (2) as follows: ΔV (t) = V (t) ) −V ′ (t) = (C × ρ × L 2 ) (G (t) −G ′ (t)) (3).
【００１７】しかして、上記の測定器による読み値Ｖ
（ｔ）とＶ'（ｔ）との差であるΔＶ（ｔ）は、測定器
に予め設定された前述の標準定数Ｃに基づく値である。
ところが実際にはバル−ン膨張容量はＸｍｌであり、こ
のとき定数Ｃは真の定数、即ち前記補正定数Ｃｒとして
置き換えることができる。 Ｘ＝（Ｃｒ×ρ×Ｌ2）〔Ｇ（ｔ）−Ｇ’（ｔ）〕 （４） 前記式（３）、（４）より Ｃｒ／Ｃ＝Ｘ／△Ｖ （５） この更正された定数Ｃｒと元の定数Ｃとの比を用い、こ
れによって、測定器の読み値を更正することにより正確
な心室容積値を得ることができる。Therefore, the reading value V by the above measuring instrument
ΔV (t), which is the difference between (t) and V ′ (t), is a value based on the above-mentioned standard constant C preset in the measuring instrument.
However, the balloon expansion capacity is actually Xml, and the constant C can be replaced by a true constant, that is, the correction constant Cr. X = (Cr × ρ × L 2 ) [G (t) −G ′ (t)] (4) From the formulas (3) and (4), Cr / C = X / ΔV (5) The ratio of the constant Cr and the original constant C is used, which allows an accurate ventricular volume value to be obtained by calibrating the meter reading.
【００１８】[0018]
【実施例】複数対の電極を埋設したカテ−テルを心室内
に挿入し、１対又は２対以上の電極間に微弱な交流電流
を定常的に流し、残りの電極間を流れる微弱電流のイン
ピ−ダンス変化を継続的に計測して心室容積を測定する
コンダクタンスカテ−テルシステム測定器として、オラ
ンダレイコム社製のＳＩＧＭＡ５を用いた。この測定器
において、カテ−テルの電極間距離Ｌを定め、また定数
Ｃを定め、更に血液抵抗値ρを実測しておくと、時々刻
々変化するコンダクタンスＧ（ｔ）を検出し、次式 Ｖ（ｔ）＝Ｃ×ρ×Ｌ2×Ｇ（ｔ）＋Ｖｃ （１） に基づいて、実時間でボリュウムＶ（ｔ）を算定し、そ
の値を刻々表示する。EXAMPLE A catheter having a plurality of pairs of electrodes embedded therein is inserted into a ventricle, and a weak AC current is constantly applied between one or more pairs of electrodes, and a weak current flowing between the remaining electrodes is As a conductance catheter system measuring instrument for continuously measuring impedance changes to measure ventricular volume, SIGMA5 manufactured by Reycom Co., Ltd. in the Netherlands was used. In this measuring device, the distance L between the electrodes of the cathode and the electrode is determined, the constant C is determined, and the blood resistance value ρ is measured. Then, the conductance G (t) that changes from moment to moment is detected, and the following formula V (T) = C × ρ × L 2 × G (t) + Vc Based on (1), the volume V (t) is calculated in real time and the value is displayed moment by moment.
【００１９】しかして、本発明においては、上記定数Ｃ
を、的確な値に更正し、正確な心室容積を測定するもの
であるが、この定数Ｃの更正は次のようにして行った。
図２に示すバル−ン付きのカテ−テルを心室に導入し
た。その後バル−ンに生理食塩水入れて膨張させた。こ
の膨張容量は３．５ｍｌであった。また、膨張前後でＳ
ＩＧＭＡ５の測定器の容積値Ｖ（ｔ）が２８．０ｍｌか
ら２３．８ｍｌに変化した。Therefore, in the present invention, the above constant C
Was corrected to an accurate value to measure the accurate ventricular volume, and the constant C was corrected as follows.
The balloon catheter shown in FIG. 2 was introduced into the ventricle. Then, saline was added to the balloon to inflate it. The expansion capacity was 3.5 ml. In addition, before and after expansion S
The volume value V (t) of the measuring instrument of IGMA5 changed from 28.0 ml to 23.8 ml.
【００２０】この容積測定値の差△Ｖ＝２８．０−２
３．８＝４．２、及びＸ＝３．５を、前記（５）式に代
入すると、 Ｃｒ／Ｃ＝３．５／４．２≒０．８３ となる。この数値０．８３を元のＣに乗算すれば、更正
した定数が得られる。また、測定器ＳＩＧＭＡ５に表示
された容積値Ｖ（ｔ）に、０．８３を乗ずれば、更正さ
れた心室の更正値が得られる。更に、この数値をＣに乗
ずる代わりに血液抵抗値ρに乗じ、その値ρ’を設定し
てもよい。This difference in volume measurement value ΔV = 28.0-2
Substituting 3.8 = 4.2 and X = 3.5 into the equation (5), Cr / C = 3.5 / 4.2≈0.83. By multiplying the original C by this numerical value 0.83, a corrected constant can be obtained. Further, by multiplying the volume value V (t) displayed on the measuring device SIGMA5 by 0.83, the corrected value of the calibrated ventricle can be obtained. Further, instead of multiplying this value by C, the blood resistance value ρ may be multiplied and the value ρ ′ may be set.
【００２１】[0021]
【発明の効果】本発明の心室容積測定法を用いると、心
臓の形状個体差による容積測定誤差が簡単に補正でき、
したがって従来のコンダクタンスカテ−テルシステムに
よる測定法の問題点を解消し、心室の形状にもとづく測
定値の誤差の少ない、正確な測定を行うことができる。
また、この方法は従来のコンダクタンスカテ−テルシス
テムのカテ−テルに単に電気絶縁性の膨張可能なバル−
ンを組み合わせて用いればよいので極めて簡単である。
しかして、本発明の測定法及びこの測定に用いるカテ−
テルは、今後の心臓機能を解明し且つ定量化するうえで
大いに役立つものである。By using the ventricular volume measuring method of the present invention, the volume measuring error due to the individual difference in the shape of the heart can be easily corrected,
Therefore, the problem of the conventional measuring method using the conductance catheter system can be solved, and accurate measurement can be performed with little error in the measured value based on the shape of the ventricle.
Also, this method is simply an electrically insulative inflatable balloon to the catheter of the conventional conductance catheter system.
It is very simple because it can be used in combination.
Therefore, the measurement method of the present invention and the category used for this measurement
Tell is of great help in elucidating and quantifying future cardiac function.
【図１】本発明のカテ−テルの一例の斜視図FIG. 1 is a perspective view of an example of a catheter of the present invention.
【図２】本発明のカテ−テルのバル−ンを膨張させたと
きの斜視図FIG. 2 is a perspective view when the balloon of the catheter of the present invention is expanded.
【図３】従来のカテ−テルの斜視図FIG. 3 is a perspective view of a conventional catheter.
１ カテ−テルチュ−ブ ２ カテ−テルの先端 ３〜１０ 電極 １１ バル−ン １２ 孔 DESCRIPTION OF SYMBOLS 1 Cathel tube 2 Cattel tip 3-10 Electrode 11 Balloon 12 Hole
Claims (2)
内に挿入し、１対又は２対以上の電極間に微弱な交流電
流を定常的に流し、残りの電極間を流れる微弱電流のイ
ンピ−ダンス変化を継続的に計測して心室容積を測定す
るコンダクタンスカテ−テルシステム測定法において、
心室内で電気絶縁性のバル−ンを膨張させ、その際のバ
ル−ンの膨張容量と膨張前後の心室容積測定値の差との
比を用いて心室容積測定値を更正することを特徴とする
心室容積測定方法。1. A catheter in which a plurality of electrodes are embedded is inserted into a ventricle, and a weak alternating current is constantly applied between one pair or two or more pairs of electrodes, and a weak current flowing between the remaining electrodes. In the conductance catheter system measurement method for measuring the ventricular volume by continuously measuring the impedance change,
It is characterized in that an electrically insulating balloon is expanded in the ventricle, and the measured ventricular volume is calibrated using the ratio of the expansion capacity of the balloon and the difference between the measured ventricular volume before and after expansion. Method for measuring ventricular volume.
内に挿入し、１対又は２対以上の電極間に微弱な交流電
流を定常的に流し、残りの電極間を流れる微弱電流によ
り生じたインピ−ダンス変化を継続的に計測して心室容
積を測定するコンダクタンスカテ−テルシステムに用い
るカテ−テルであって、該カテ−テルは電気絶縁性の膨
張自在のバル−ンを有することを特徴とする心室容積測
定用カテ−テル。2. A catheter in which a plurality of electrodes are embedded is inserted into a ventricle, and a weak alternating current is constantly applied between one or more pairs of electrodes, and a weak current flowing between the remaining electrodes is used. A catheter for use in a conductance catheter system for measuring ventricular volume by continuously measuring the generated impedance change, the catheter having an electrically inflatable balloon. A catheter for measuring ventricular volume, which is characterized by:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP04065102A JP3092027B2 (en) | 1992-03-23 | 1992-03-23 | Ventricular volume measuring method and catheter for measurement |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP04065102A JP3092027B2 (en) | 1992-03-23 | 1992-03-23 | Ventricular volume measuring method and catheter for measurement |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH05269136A true JPH05269136A (en) | 1993-10-19 |
| JP3092027B2 JP3092027B2 (en) | 2000-09-25 |
Family
ID=13277211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP04065102A Expired - Fee Related JP3092027B2 (en) | 1992-03-23 | 1992-03-23 | Ventricular volume measuring method and catheter for measurement |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3092027B2 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003026504A1 (en) | 2001-09-20 | 2003-04-03 | Japan As Represented By President Of National Cardiovascular Center | Automatic, continuous measuring device for a ventricle volume |
| JP2010046512A (en) * | 2003-01-24 | 2010-03-04 | Proteus Biomedical Inc | Method and system for measuring cardiac parameter |
-
1992
- 1992-03-23 JP JP04065102A patent/JP3092027B2/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003026504A1 (en) | 2001-09-20 | 2003-04-03 | Japan As Represented By President Of National Cardiovascular Center | Automatic, continuous measuring device for a ventricle volume |
| JP2010046512A (en) * | 2003-01-24 | 2010-03-04 | Proteus Biomedical Inc | Method and system for measuring cardiac parameter |
Also Published As
| Publication number | Publication date |
|---|---|
| JP3092027B2 (en) | 2000-09-25 |
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