JPH05137785A - Balloon infuser - Google Patents

Abstract

PURPOSE:To decrease the grades of balloon infusers by providing a liquid drug flow rate control section between a communicating pipe and the front end of a tube or within the tube at the front end of the tube. CONSTITUTION:The liquid drug flow rate control section 31 which is closed at the front end on a downstream side and is formed of a pipe, etc., having one piece of fine hole is connected between the front end 40 of the tube 32 and the communicating pipe 34 by a connector 30. The flow rate control section 31, the tube 32 and the connector 30 are thermally welded and connected by a sheath part 41 having the inside diameter larger than the outside diameters of the flow rate control section 31 and the tube 32 in such a case. The flow rate control section 31 is otherwise disposed within the tube 30 at the front end 40 of the tube 32. The front end 40 of the tube 32 is thermally welded and molded into the connector 30 in such a case. Further, a filter 42 for removing micromaterials contained in the liquid drug in the balloon 3 may be provided between the pipe 34 and section 31. The flow rate of the flow rate control section 31 is controlled to 20ml/hour.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION The present invention provides a predetermined amount of drug solution in the body,
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a balloon infuser for injecting, and more particularly, to a balloon infuser capable of injecting a drug solution stored under pressure in a balloon into a patient at a constant speed in a short time. ..

[0002]

2. Description of the Related Art Conventionally, as a means for gradually injecting a drug solution such as an antibiotic, an anti-cancer agent or an anesthetic into a blood vessel, a bladder, etc., the drug solution is stored in a balloon made of an elastic material.
There is known a device (Japanese Patent Application Laid-Open No. 2-11160) for continuously injecting a liquid medicine into a human body for a long time by utilizing the contracting force of the liquid. The balloon intruder described in the publication.
Includes a balloon part for accommodating the balun and a chemical liquid outflow assembly mainly having a tube having a flow rate control part composed of a fine hole pipe, and provided in the chemical liquid inflow / outflow part of the balun part. The liquid medicine in the balloon is flown out by piercing the stopper with a liquid medicine injection needle provided at the end of the liquid medicine outflow assembly.

In using the balloon injector, first, the injection needle of a syringe is inserted into the stopper to inject the liquid medicine into the balloon, and when the prescribed amount of the liquid medicine is filled, the needle is closed. Remove from Then, a drug solution injection needle provided at the end of the drug solution outflow assembly is inserted into the stopper to inject the drug solution in the balloon into the patient's body. However, this balloon inuser has a drawback that the liquid medicine leaks from the outer surface of the needle depending on how the needle is inserted into the stopper. Further, this balloon intruder causes the chemical solution to flow out from one end of the outer shaft, which is the support shaft of the balloon provided inside the balloon, so that there is a clearance between the inside of the outer shaft and the outer surface of the inner shaft. However, even if the balloon is completely contracted, a certain amount of drug solution may inevitably remain in the outer shaft, and if the drug solution is expensive such as morphine hydrochloride and anti-cancer drug, there is a lot of residual solution. That is a big financial problem.

The inventors of the present invention have invented a balloon fuser shown in FIG. 11 and FIG. 12 as a balloon fuser which solves these drawbacks and applied for a patent (Japanese Patent Application No. 2-21).
No. 6621). FIG. 11 is an overall explanatory view of the balloon inuser, showing a state in which the communication pipe is not fitted or screwed into the connector of the housing, and FIG. 12 is shown in FIG.
FIG. 9 is an enlarged cross-sectional view showing a state when the balloon of the housing shown in FIG. The balloon intruder of FIGS. 11 and 12 is a chemical liquid outflow assembly d having a balloon portion c formed of a housing 47 for accommodating the balloon 46 and a flow rate control portion 48 for adjusting the flow rate of the chemical liquid. It consists of The balloon 46 includes a rod-shaped inner shaft 50 shown in FIG.
A cylindrical outer shaft 51 slidably mounted on the inner shaft, and the inner shaft.
An inner bearing 52 integrally formed with the inner shaft at one end of the outer shaft 51 opposite to the outer shaft 51, and both shafts so as to cover the inner shaft 50 and the outer shaft 51. A ball 46 made of an elastic material, which is provided outside and has one end closely fixed to the inner shaft 50 and the other end closely fixed to the outer shaft 51. An adapter 53, which is a chemical liquid inlet / outlet portion, is formed at one end of the housing 47, and a chemical liquid passage is formed through the inside of the inner bearing 52.
It communicates with 54. In the chemical liquid passage 54, when the chemical liquid is injected into the balloon 46, the chemical liquid in the balloon is prevented from flowing out, and when the chemical liquid is discharged from the balloon 46, the chemical liquid passage 54 is opened from the open end. A communication pipe 55 provided at the end of the chemical liquid outflow assembly d is inserted, and a check valve 56 having a valve opening is provided.

[0005]

However, when using such a balloon-in-user, the flow rate control unit 48 for adjusting the flow rate of the drug solution is provided in the connection tool 57 for connecting the venous needle and the arm of the patient. Since the drug solution is injected into the patient's body after being fixed with a bandage or the like, there is a problem that the flow rate of the drug solution is affected by the patient's body temperature. The temperature of the patient's arm depends on the individual difference and the condition of the patient at that time.
In order to manufacture a balloon-in-heater adjusted so that the drug solution is supplied to the patient's body at a desired time since it is different up to ° C, many types of balloon-in-houser are prepared in advance according to the condition. There is a problem to be addressed.

[0006]

The inventors of the present invention have made extensive studies to solve these problems, and as a result, have solved it by installing a flow rate control unit in a drug solution outflow assembly at a position that is not affected by the body temperature of a patient. The present invention has been achieved by finding that That is, according to the present invention, a cylindrical outer shaft, an inner shaft housed in the outer shaft, and an outer shaft of the both shafts are provided so as to cover these both shafts, and one end of the outer shaft is closely fixed to the outer shaft. , A balloon made of an elastic material, the other end of which is closely fixed to the inner shaft, a common chemical liquid passage for injecting and flowing out a chemical liquid which communicates with the inside of the balloon, and an open end of the chemical liquid passage. An adapter of a fitting type or screw type connecting tool is formed in the part,
In addition, when the chemical liquid is injected into the balloon, the chemical liquid is prevented from flowing out into the chemical liquid passage, and when the chemical liquid flows out from the balloon, the communication is inserted from the open end of the chemical liquid passage. A valve part provided with a check valve capable of opening a valve by a pipe, a connector for injecting a drug solution into the body is provided at the rear end of the tube, and a valve is provided at the tip of the tube.
Flow rate for controlling the amount of the chemical liquid in a balloon infusor comprising a chemical liquid outflow assembly provided with a connector that can be fitted or screwed with a communication pipe having a length capable of communicating inside The control unit connects the communication pipe and the
A balloon-in-heater provided inside the tube between the tip of the tube and substantially the tip of the tube. Further, according to the present invention, in the above-mentioned ball-in fuser, a filter for removing minute substances in the chemical liquid is provided between the communication pipe and the end of the flow rate control unit. Is. Further, the present invention is the above-described balloon in- user, in which the flow rate of the chemical liquid in the flow controller is controlled to be at least 20 ml / hour.

FIG. 1 is an explanatory view of an embodiment of the balloon infuser of the present invention, showing the state in which the balloon portion is not connected to the chemical liquid outflow assembly portion, and FIG. 2 is FIG. 3 is an enlarged cross-sectional view of the balloon portion when the balloon is filled with the chemical liquid. FIG. 3 shows the connector of the chemical liquid outflow assembly portion and the luer taper-shaped adapter of the balloon portion shown in FIG. FIG. 4 is an enlarged cross-sectional view, and FIG. 4 shows the connector shown in FIG.
5 is an explanatory view showing a state in which it is inserted into the linear adapter, FIG.
FIG. 6 is an explanatory view of injecting the drug solution in the syringe into the balloon, and is an explanatory view showing a state in which the syringe and the balloon portion are not connected, and FIG. 6 is a drawing of the drug solution in the balloon from the syringe shown in FIG. 7 and 8 are diagrams showing the relationship between the discharge amount of the chemical liquid in the balloon and the discharge amount, and FIGS. 9 and 10 are the vicinity of the connector having the communication pipe of FIG. FIG.

FIG. 1 is an explanatory view of an embodiment of the balloon infusor of the present invention, which is composed of a balloon portion a and a chemical liquid outflow assembly portion b. The balloon portion a is a portion for accommodating the chemical liquid and a drive portion for moving the chemical liquid to the injection site of the human body, and the rod-shaped inner shaft 1
And a cylindrical outer shaft 2 slidably mounted on the inner shaft 1.
And a balun 3 provided outside of these shafts, and an inner bearing 4 formed integrally with the inner shaft 1. An umbrella-shaped member 5 is fixed to one end of the outer shaft 2 and the end opposite to the side covered by the inner shaft 1.

The balloon 3 has a cylindrical or spherical shape and is provided outside the inner shaft 1 and the outer shaft 2 so as to cover the inner shaft 1 and the outer shaft 2. One end of the ball 3 is attached to the inner shaft 1. The other end is hermetically fixed to the outer shaft 2 by a seal means 6 such as an O-ring. As the balloon 3, various sizes and wall thicknesses can be used according to the amount of drug solution to be injected into the patient, the injection time, etc., and the present invention is not particularly limited. The balloon 3 expands when filled with a chemical solution, and the rectangular balloon has a structure capable of expanding not only in the radial direction but also in the longitudinal direction.

The outer shaft 2 moves in the axial direction with the inner shaft 1 as a guide in association with the movement of the balloon 3, and the relationship between the position and the amount of the chemical liquid remaining in the balloon 3 is constant. Therefore, by providing a scale on the inner shaft 1 or the housing 7, the outflow amount of the chemical liquid can be confirmed. A water pressure resistant filter 8 is provided at one end of the outer shaft 2 and at the end opposite to the side covered by the inner shaft 1. The water pressure resistant filter 8 is a member which plays a role of expelling the air remaining in the balloon 3 to the outside at the time of injecting the chemical liquid, and may be made of polyester, fluororesin or a laminate of these. it can.

Balloon 3 is made of an elastic material, and its material is silicone rubber, butyl rubber, nitrile butadiene rubber, poly-1,4-butadiene, polyisoprene, polyurethane, butadiene styrene copolymer, polystyrene polybutadiene. Elastic polymers or natural rubbers such as hydrogenated substances of block copolymers, mixtures of these polymers,
Alternatively, a processed substance obtained by removing an additive of these substances and then adding a harmless antioxidant to a human body, a laminate or the like can be mentioned.

An inner bearing 4 is formed integrally with the inner shaft 1 at one end of the inner shaft 1 opposite to the outer shaft 2 exterior side. The inner bearing 4 is a short cylindrical member, and a chemical solution inflow / outflow port is formed at an end portion on the inner shaft 1 side. The chemical solution outflow port communicates with the chemical solution passage of the housing 7 through the inside of the inner bearing 4. The housing 7 prevents the ball 3 from being damaged by touching an external sharp object, and when the liquid leaks from the ball 3 due to a defect such as a pinhole of the ball itself, the housing 7 is exposed to the outside. It is a part that functions to seal the chemical liquid so that the chemical liquid does not scatter. An air vent opening 10 is provided at an appropriate location on the housing 7.
It is preferable that the opening 10 is provided with a hydrophobic filter 11 through which air can pass but a drug solution cannot pass.

One end surface of the housing 7 is closed by a cap 12, and the central part of the cap 12 is filled with a chemical solution into the balloon 3 or is injected from the ball 3 into a predetermined location. At this time, a chemical liquid passage 13 is formed which serves as a flow path for the chemical liquid. As shown in FIGS. 2 to 4, a duckbill type check valve 14, a fixed disk 15 and a seal means 16 are provided in the chemical liquid passage 13 from the side of the balloon 3. The duckbill type check valve 14 has a structure in which the closed end of the valve has a sharp shape like a duckbill's beak, and allows the chemical liquid to flow into the balloon 3, but prevents the flow in the opposite direction. Has become. As the check valve 14, in addition to the duck bill type valve, an umbrella valve, a flap valve, a poppet valve, and a baud valve.
For example, a fluorine valve, nylon, polyolefin, polyvinyl chloride, polycarbonate, silicone resin or the like can be used as the valve material. The fixed disk 15 supports the substrate of the check valve 14, and has an opening 17 formed at the center for inflow and outflow of the chemical solution.

An O-ring as a sealing means 16 is disposed in an annular recess 18 formed by a lock adapter 19 which is a connecting tool and a fixed disk 15. The inner diameter of the O-ring is the same as or smaller than the outer diameter of the communication pipe, so that the sealing property when the communication pipe is inserted into the chemical liquid passage 13 is enhanced. The lock adapter 19 is a substantially cylindrical connector having an inner surface formed in a luer taper shape. The lock adapter 19 is fitted in a recess 20 formed in the cap 12. The chemical solution outflow assembly b is provided on the outer periphery of the end of the lock adapter-19.
Is formed with a screw portion 21 for connecting.

The chemical liquid outflow assembly b is a lock adapter-
A connector part 30 which is a connecting tool to be connected to 19, a flow rate control part 31 for controlling the amount of chemical liquid, and a chemical liquid injection tube 32.
And a connector 33. One end of the connector part 30 has a check valve when connected to the lock adapter-19.
A communication pipe 34 having a length capable of pushing and opening 14 to communicate with the inside of the balloon 3 is provided. The communication pipe 34 can be made of a synthetic resin such as polycarbonate, polyvinyl chloride, or polyolefin, or a metal such as stainless steel. The communication pipe 34 is fixed to the inner peripheral surface of the connector portion 30. As shown in FIG. 4, the protruding length L of the communication pipe 34 is set to such a length that the duckbill type check valve 14 can be expanded when the connector portion 30 and the lock adapter 19 are connected. .. As a result, the non-return effect of the check valve 14 is forcibly released, and the valve can be removed without using the injection needle.
The chemical liquid filled in the inlet 3 can be discharged. The screw portion 35 on the connector portion side is screwed with the screw portion 21 formed on the lock adapter 19 to connect the balloon portion a and the chemical liquid outflow assembly b. This connection may be made by fitting instead of screwing.

The flow rate control section 31 is a section for controlling the flow rate of the chemical liquid, and is located on the downstream side as proposed in Japanese Patent Application Laid-Open No. 1-135356, Japanese Patent Application Laid-Open No. 2-11160 or Japanese Patent Application Laid-Open No. 3-140163. It is possible to use a pipe having a closed tip and having at least one fine hole, a perforated pipe such as a porous glass pipe, a stainless pipe having a small inner diameter, and a synthetic resin pipe. The flow rate control unit 31 is provided inside the tube 32 between the tip 40 of the tube 32 and the communication pipe 34 or substantially at the tip 40 of the tube 32. When the flow rate control unit 31 is provided between the tip 40 of the tube 32 and the communication pipe 34, for example, the flow rate control unit
As shown in FIG. 9, the reference numeral 31, the tube 32, and the connector 30 are a flow control section 31, a tube 32, and a connector having an outer jacket 41 having an inner diameter larger than the outer diameter of the tube 32. -30 can be heat-welded and molded. In this case, the flow rate control unit 31 is preferably a synthetic resin pipe having a small inner diameter. In addition, the flow rate control unit 31 includes a tube as shown in FIG.
It may be provided inside the tube 32 substantially at the tip 40 of the tube 32. In this case, the tip 40 of the tube 32 is the connector-
It can also be heat-welded and molded into the inside of 30. The flow rate of the chemical solution in the flow rate control unit 31 is preferably controlled to be at least 20 ml / hour. A flow rate of the chemical liquid of less than 20 ml / hour is not preferable because it tends to take time to remove air from the chemical liquid outflow assembly b.

Between the communication pipe 34 and the flow rate control unit 31,
A filter 42 for removing minute substances contained in the chemical liquid in the balloon 3 may be provided. As the filter 42, a fibrous material, a sintered material or the like is used. The tube 32 is made of soft polyvinyl chloride, polypropylene, polyester or the like, and has a luer taper-like connecting member 33 provided at the other end thereof, through which the venous needle or PSV is connected.
Sets etc. are connected. The connection tool 33 may be equipped with a check valve (not shown) for preventing backflow of the drug solution due to venous pressure or the like.

Next, an example of a method of using the balloon infuser of the present invention will be described. To inject the drug solution into the balloon, insert a syringe of a syringe into the drug solution passage as shown in FIGS. 5 and 6, and attach the syringe to the inner surface of the lock adapter 19 in the luer taper shape. It is done by pressing. At this time, the needle base tip of the syringe 22 has a check valve 14
On the entrance side of. The insertion part is wide because the inlet is wide,
The filling pressure becomes smaller as compared with the case of using a conventional injection needle, the injection is facilitated, and the injection operation can be completed in a short time.

The balloon 3 expands as the chemical is filled. At this time, the internal air remaining in the balloon 3 is expelled to the outside through the water pressure resistant filter 8. Further, as the balloon 3 expands, the outer shaft 2 which is externally mounted on the inner shaft 1 slides in the longitudinal direction and advances along the surface of the housing 7. When the prescribed amount of drug solution is filled, the syringe is pulled out from the lock adapter-19. When the liquid filling is completed,
The umbrella-shaped member 5 and the inner surface of the end portion of the housing 7 are aligned with each other, and the balloon is prevented from bursting due to bending and vibration when the balloon 3 expands. Next, as shown in FIG. 4, the connector portion 30 of the chemical liquid outflow assembly portion b and the inside of the lock adapter-19 are connected. At this time, the communication pipe 34 of the connector portion 30 pushes the check valve 14 wide so that the interior of the balloon 3 and the communication pipe 34 are in communication with each other. After that, after connecting to a PSV set or the like via a connecting tool 33 and performing a predetermined operation such as air bleeding, the drug solution in the balloon 3 is injected into the patient's body while the flow rate is controlled by the flow rate control unit 31. Is done.

[0020]

The present invention is to inject the drug solution in the balloon into the patient by utilizing the contracting force of the balloon which is filled with the drug solution and expanded. Since the flow rate control unit that controls the outflow rate of the drug solution in the balloon is provided close to the housing on the tip side of the drug solution injection tube, the balloon containing the drug solution in a bag such as a pocket of clothing is not provided. It is stored with the housing that contains it. As a result, the flow rate controller does not come into close contact with the body, so the flow rate is not affected by the body temperature and the flow rate is desired at the desired flow rate.
The drug solution in the tank can be drained. Further, since the chemical liquid in the balloon of the present invention is structured to flow out from the end portion of the inner shaft, compared with the conventional balloon infusor in which the chemical liquid flows out from the end portion of the outer shaft, -There is not much liquid remaining in the container. Furthermore, since the connection between the balloon part and the drug solution outflow assembly is fitted or screwed through the check valve provided in the balloon part, the conventional stopper is pierced with the injection needle to allow the drug solution to be injected. Compared with the case of injecting into a balloon, the filling pressure is small and it is easy to inject the drug solution.
There is no leakage of the drug solution inside.

[0021]

EXAMPLES An example of the present invention will be described below with reference to examples.

Example 1 A vulcanized natural rubber tubular body (made by Komine Rubber Co., Ltd.) was mixed with an acetone / hexane mixed solvent (mixing volume ratio 1:
Soxhlet extraction was carried out for 3 hours in 2), and the additives in the natural rubber tubular body were extracted and removed. Then the tubular body
3,5-Trimethyl-2,4,6-tris (3,5-di-t-butyl-4-hydroxybenzyl) benzene (hereinafter referred to as BHT) was mixed with acetone / hexane mixed solvent (mixing volume ratio 1: 2). BHT which is an antioxidant is immersed in the solution (concentration 0.01 g / ml) at a temperature of 25 ° C. for 24 hours,
Was impregnated. After that, the tubular body was washed with ethanol and washed at 25 ° C.
It was dried at a temperature of 12 hours. This treated natural rubber tubular body was incorporated into the balloon infuser shown in FIG.
0 ml of water was charged into the balloon. Next, extra-fine polyvinyl chloride pipe (outer diameter 0.3 mm, inner diameter 0.114 mm, length 20
mm) was attached as shown in FIG. 9, and the water in the balloon was dropped from the venous needle attached to the connector.
FIG. 7 shows the relationship between the discharge time of water in the balloon and the discharge amount at this time.

[0022]

Example 2 The treated natural rubber tubular body obtained in Example 1 was incorporated into a balloon infuser shown in FIG.
Of water was charged into the balloon. Next, extra-fine polyvinyl chloride pipe (outer diameter 0.3 mm, inner diameter 0.13 mm, length 20 mm)
As shown in FIG. 10, the flow rate control unit consisting of was attached, and the water in the balloon was dropped from the vein needle attached to the connector. FIG. 8 shows the relationship between the discharge time of water in the balloon and the discharge amount at this time. As is clear from FIGS. 7 and 8, the water in the balloon was dropped at a substantially constant flow rate.

[0023]

According to the present invention, since the flow rate control unit for controlling the outflow rate of the drug solution in the balloon is provided close to the housing on the tip side of the drug solution injection tube, the flow rate control unit can be used for clothing. It is housed in a bag together with a housing containing a balloon containing a chemical solution. Therefore, the flow rate control unit does not come into close contact with the body, and the drug solution in the balloon can flow out at a desired flow rate without being affected by the body temperature that varies depending on individual differences and health conditions. As a result, it has become possible to manufacture the balloon inusers with a reduced variety. Also,
Since the chemical liquid in the balloon of the present invention is structured to flow out from the end portion of the inner shaft, the residual liquid amount after the chemical liquid in the balloon is discharged is small, and when an expensive chemical is used. Has an economic effect on. Further, since the check valve is provided in the balloon part to fit or screw the balloon part and the drug solution outflow assembly, the conventional stopper is pierced with the injection needle to allow the drug solution to flow. As compared with the case of injecting into the balloon, the filling pressure is small and the injection of the drug solution is easy, and the drug solution in the balloon does not leak from the vicinity of the injection needle.

[Brief description of drawings]

FIG. 1 is an explanatory view of an embodiment of a balloon infusor of the present invention, showing a state in which the balloon portion is not connected to a chemical liquid outflow assembly portion.

FIG. 2 is an enlarged cross-sectional view of a balloon portion when the balloon is filled with a chemical solution.

FIG. 3 is an enlarged cross-sectional view of the connector of the chemical liquid outflow assembly portion and the luer taper-shaped adapter of the balloon portion shown in FIG.

FIG. 4 is an explanatory view showing a state when the connector shown in FIG. 3 is inserted into a luer taper-shaped adapter.

FIG. 5 is an explanatory diagram when injecting the drug solution in the syringe into the balloon, and is an explanatory diagram showing a state in which the syringe and the balloon body are not connected.

FIG. 6 is an explanatory view when the drug solution is filled into the balloon from the syringe shown in FIG.

FIG. 7 is a diagram showing the relationship between the discharge time and the discharge amount of the chemical liquid in the balloon.

FIG. 8 is a diagram showing the relationship between the discharge time and the discharge amount of the chemical liquid in the balloon.

9 is an enlarged cross-sectional view of the vicinity of the connector having the communication pipe of FIG.

10 is an enlarged cross-sectional view of the vicinity of the connector having the communication pipe of FIG.

FIG. 11 is an overall explanatory view of the balloon in-user of Japanese Patent Application No. 2-216621, showing a state where the communication pipe is not fitted or screwed into the connector of the housing.

12 is an enlarged cross-sectional view showing a state when the balloon shown in FIG. 11 is filled with a chemical liquid.

[Explanation of symbols]

 a Balloon part b Chemical liquid outflow assembly part 1 Inner shaft 2 Outer shaft 3 Balloon 7 Housing 14 Check valve 19 Lock adapter-30 Connector part 31 Flow control part 32 Tube 34 Communication pipe

Claims (3)

[Claims] 1. A cylindrical outer shaft, an inner shaft housed inside the outer shaft, and an outer shaft provided so as to cover both shafts, one end of which is closely attached to the outer shaft. , A balloon made of an elastic material, the other end of which is closely fixed to the inner shaft, a common chemical liquid passage for injecting and flowing out a chemical liquid which communicates with the inside of the balloon, and an open end of the chemical liquid passage. An adapter of a fitting type or screw type connecting tool is formed in the portion, and the chemical liquid in the chemical liquid passage is prevented from flowing out during injection of the chemical liquid into the balloon, A valve portion provided with a check valve capable of opening the valve by a communication pipe inserted from the open end of the liquid medicine passage when the liquid medicine flows out of the valve,
A connection tool for injecting a medicinal solution into the body is provided at the rear end of the tube, and a fitting pipe having a length of communication pipe that can communicate with the inside of the balloon is provided at the tip of the tube and can be fitted or screwed. In a balun-in-user comprising a chemical liquid outflow assembly provided with a connector, a flow rate control unit for controlling the chemical liquid amount is provided between the communication pipe and the tip of the tube or a substantial part of the tube. A ball-in fuser having a distal end provided inside the tube. 2. The balloon inuser according to claim 1, wherein a filter for removing minute substances in the chemical liquid is provided between the communication pipe and the end of the flow rate control unit. 3. The flow rate of the chemical liquid in the flow rate control unit is at least 20 ml.
3. The balloon injector according to claim 1 or 2, which is controlled so as to be / hour.