JPH0476708B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a dosing device for an automatic injection device for administering a drug solution to a test animal.

[Conventional technology]

It is equipped with a drive unit that loads a syringe and controls the forward and backward movement of the plunger inserted into the syringe, inhales the drug solution from the drug container into the syringe, and automatically (powers) administers the inhaled drug solution to the test animal. Injection devices are known, and usually a dosing device is connected to this type of automatic injection device for administering a drug solution to a test animal.

FIG. 6 shows a conventional dosing device 60. FIG. The administering device 60 shown in the figure has a pen-shaped structure as a whole, and includes an administration nozzle (generally an oral probe or an intravenous needle) 62 at the tip of a main body 61, and a nozzle switch 63 at a predetermined position of the main body 61. Equipped with. and,
When the nozzle switch 63 is pressed, an automatic injection device (not shown) is activated, and the drug solution is administered to the test animal via the dosing device 60. When the nozzle switch 63 is pressed again, the automatic injection device stops operating. The supply of chemical solutions will also be stopped.

[Problem to be solved by the invention]

However, such a conventional dosing device 60 has the following problems.

First, administering a drug solution to a test animal requires considerable skill, and if you are inexperienced, the dosing nozzle 62 may pierce the esophagus or stomach of the test animal due to the tension resistance of the test animal. , there is a risk of accidentally inserting it into the trachea. On the other hand, it is not uncommon to administer drug solutions using a syringe, but when an operator who is accustomed to operating a syringe operates the above-mentioned dosing device 60, the feeling of operation is very different, making it difficult to handle and ultimately This results in the injury to the test animals mentioned above and the possibility of erroneous administration.

Second, since the dosing device 60 has an integrated electrical control system including the nozzle switch 63 and a drug supply system including the dosing nozzle 62, it is necessary to replace the entire dosing device 60 each time a different drug is to be administered. , is extremely uneconomical.

The present invention solves the problems that exist in the conventional technology, and aims to provide a dosing device for an automatic injection device that is easy to handle and is economical.

[Means to solve the problem]

A dosing device 1 according to the present invention includes a cylindrical main body 2 having a flange 3 at an intermediate position of an outer periphery 2s, a dosing nozzle 4 supported at the front of the main body 2, and a dosing nozzle 4.
A chemical liquid tube 5 communicating with the main body 2 is inserted so as to be displaceable over a predetermined range in the axial direction,
The operating rod section 6 partially protrudes from the rear end of the main body section 2, the elastic member 7 biases the operating rod section 6 in the protruding direction, and the operating rod section 6 opens and closes in response to displacement of the operating rod section 6 to supply a chemical solution. It is characterized by comprising a nozzle switch section 8 for controlling. In this case,
The administration nozzle 4 and the liquid medicine tube 5 can be configured to be detachable from the main body 2 .

[Effect]

According to the dosing device 1 according to the present invention, since the overall shape is similar to a syringe, an operator can hold it in his/her hand like a normal syringe, and the operating rod portion 6 is oriented in the axial direction with respect to the main body portion 2. Because it is displaced to
It can be operated in the same way as a plunger in a regular syringe.

That is, since the operating rod portion 6 protrudes from the rear end of the main body portion 2 and is biased in the protruding direction by the elastic member 7, in the natural state it protrudes to the maximum position and the nozzle switch portion 8 is opened (off). . In this state, the operation of the automatic injection device is stopped, and the supply of the drug solution is stopped. On the other hand, if the operating rod section 6 is pushed against the elasticity of the elastic member 7, the nozzle switch section 8 is closed (turned on). As a result, the automatic injection device is activated and the drug solution is supplied to the dosing nozzle 4. Note that when the pressing operation of the operating rod section 6 is released, the nozzle switch section 8 is opened (off) and the supply of the chemical solution is stopped.

Furthermore, since the dosing nozzle 4 and the drug tube 5 are configured to be detachable from the main body 2, only the drug solution supply system can be replaced.

〔Example〕

Below, preferred embodiments according to the present invention are listed,
This will be explained in detail based on the drawings.

First, regarding the configuration of the dosing device 1 according to the present invention,
This will be explained with reference to FIG. 1 (FIG. 2).

Reference numeral 2 denotes a cylindrical main body portion, and a flange portion 3 is provided at an intermediate position of the outer peripheral portion 2s. On the other hand, a support 11 having the same outer diameter as the main body 2 is attached to the front end of the main body 2 . In this case, as shown in FIG. 4, the support body 11 and the main body portion 2 are configured to be removable, for example, by fitting them into protrusions and recesses. Moreover, the tip of the support body 11 is integrally provided with a nozzle attachment part 11i, and an oral probe (or intravenous injection needle) 12 for administering a drug solution is attached thereto.
The oral probe 12 can be, for example, a flexible probe using Teflon in the middle. Furthermore, a chemical liquid tube 5 is provided on the peripheral surface 11s of the support 11.
The tube 5 communicates with the oral probe 12 via a liquid path 13 provided inside the support 11.

On the other hand, an operating rod portion 6, which partially protrudes from the rear end of the main body portion 2, is inserted into the main body portion 2. The operating rod portion 6 is prevented from coming off from the main body portion 2 by a stopper 6s provided at an intermediate position thereof, and thereby becomes freely displaceable at least in the axial direction over a predetermined range. Further, a coil spring 7c is disposed inside the main body 2 to bias the operating rod 6 in the direction of protruding from the main body 2. On the other hand, a switch holder 14 is fixed inside the main body part 2. The nozzle switch section 8 is constructed by attaching a fixed contact 8p and a movable contact 8q to the switch holder 14, and each contact 8p, 8q is connected to a cord 15 led out to the outside of the main body section 2. The nozzle switch section 8 opens and closes (on and off) in response to the forward and backward movement of the operating rod section 6.
Accordingly, the supply of the drug solution to the oral probe 12 is controlled (supply control or stop control).

With the above configuration, the overall shape is similar to that of a syringe, and the operating rod portion 6 can be operated in the same manner as a plunger in a normal syringe.

Next, a liquid drug administration system including an automatic injection device including such an administration device 1 and its peripheral devices will be described with reference to FIG. 3.

21 is an electronic balance section, which is connected to the automatic injection device 20. The automatic injection device 20 has a built-in computer function, and the top panel 22 includes a keyboard 23,
In addition to disposing the display 24, the drive unit 2
5, the plunger 26p is equipped with a syringe 26 whose forward and backward movement is controlled.

On the other hand, a switch 27 is connected to the inlet/outlet 26c of the syringe 26. The switch 27 can be a three-way stopcock or the like, and has the function of selectively connecting the liquid medicine container 28 containing the liquid medicine or the liquid medicine tube 5 connected to the dosing device 1 according to the present invention to the entrance/exit 26c.
Note that the code 15 of the dosing device 1 corresponds to the automatic injection device 20.
Connect to. The automatic injection device 20 also includes a printer 29 for printing out data, if necessary.
Connect.

Next, the overall function and usage method of the automatic injection device 20 including the administering device 1 will be explained.

First, switch the switch 27 to the chemical liquid container 28 side,
The plunger 26p of the syringe 26 is controlled to move in the protruding direction to inhale the medicinal liquid into the syringe 26, and when the inhalation is completed, the switch 27 is switched to the dosing device 1 side.

The operator holds the administration device 1 in his hand H as shown in FIG. 1, and inserts the oral probe 12 into the mouth of the test animal A as shown in FIG.

The dosing device 1 in its natural state has the operating rod portion 6
protrudes to the maximum position as shown in FIG. 1, so the nozzle switch section 8 is opened and no chemical solution is supplied.

On the other hand, from this state, use your thumb C to press the operating rod 6.
If you press it in the same way as a normal syringe,
As shown in FIG. 2, the nozzle switch section 8 closes,
The automatic injection device 20 controls the movement of the plunger 26p in the pushing direction. As a result, the drug solution in the syringe 26 is administered to the test animal A via the switching device 27, the drug solution tube 5, and the oral probe 12.

When the required amount of the drug solution has been administered, the user releases the thumb C from the operating rod section 6 to open the nozzle switch section 8 and stop supplying the drug solution. Thus, the automatic injection device 20 is in the supply state only while the nozzle switch section 8 is closed.

In addition, when changing the drug solution or changing the concentration, it is sufficient to remove the support 11 from the main body 2 and replace it with another support 11, and only the drug solution supply system including the oral probe 12 and the drug solution tube 5 needs to be removed. It is extremely economical because it can be replaced.

Although the embodiments have been described in detail above, the present invention is not limited to these embodiments. For example, the oral probe (administration nozzle) and drug solution tube may be configured so that they can be directly attached to and detached from the main body without using a support. Further, the nozzle switch section may be provided outside the main body section, if necessary. In addition, the detailed structure and shape can be changed arbitrarily without departing from the gist of the present invention.

〔Effect of the invention〕

As described above, the dosing device according to the present invention includes a cylindrical main body having a flange on the outer periphery, a dosing nozzle supported by the main body, a liquid medicine tube communicating with the dosing nozzle, and a liquid medicine tube displaceably inserted into the main body. Since the nozzle switch is provided with an operating rod section, an elastic member that biases the operating rod section, and a nozzle switch section that opens and closes in response to displacement of the operating rod section, the following remarkable effects are achieved.

Since it can be operated in the same manner as a normal syringe, it can be handled easily without any discomfort, improving work efficiency, and further preventing injury to test animals and erroneous administration.

The chemical solution supply system, including the dosing nozzle, etc., is configured to be removable from the main body, which includes the electrical system such as the nozzle switch, so even when changing the chemical solution, it is sufficient to replace only the chemical solution supply system.
It is extremely economical.

[Brief explanation of the drawing]

Fig. 1: A longitudinal cross-sectional view of the dosing device according to the present invention in a drug solution stop state, Fig. 2: A longitudinal cross-sectional view of the dosing device in a drug solution supply state, and Fig. 3: Overall medical solution administration system equipped with the dosing device. System diagram, Fig. 4: A longitudinal cross-sectional view with the administration nozzle side removed from the same administration device, Fig. 5: An explanatory diagram showing the administration nozzle of the same administration device inserted into a test animal, Fig. 6 : External perspective view of a conventional dosing device. In the drawings, 1...Administrator, 2... Main body, 2s
...outer periphery, 3...flange, 4...dosing nozzle, 5
... Chemical liquid tube, 6 ... Operation rod, 7 ... Elastic material, 8 ... Nozzle switch section.

Claims (1)

[Scope of Claims] 1. A cylindrical main body having a flange at an intermediate position on the outer periphery, a dosing nozzle supported at the front of the main body, a liquid medicine tube communicating with the dosing nozzle, and An operating rod portion that is inserted so as to be displaceable over a predetermined range in the axial direction and that partially protrudes from the rear end of the main body, an elastic member that biases the operating rod portion in the protruding direction, and a displacement of the operating rod portion. 1. A dosing device for an automatic injection device, comprising a nozzle switch section that opens and closes in response to the above conditions to control the supply of drug solution. 2. Claim 1, wherein the dosing nozzle and the liquid medicine tube are configured to be detachable from the main body.
The autoinjector dosing device described.